Package: MRCorge 0.1.0

Wenmin Zhang

MRCorge: Mendelian Randomization based on the core gene hypothesis for polygenic exposures

This package performs Mendelian Randomization (MR) analyses based on the core gene hypothesis for polygenic exposures. MR CORGE identifies a small number of putative core instruments that are more likely to affect genes with a direct biological role in an exposure and obtains causal effect estimates based on these instruments, thereby reducing the risk of horizontal pleiotropy.

Authors:Wenmin Zhang [aut, cre], Tianyuan Lu [aut]

MRCorge_0.1.0.tar.gz
MRCorge_0.1.0.zip(r-4.5)MRCorge_0.1.0.zip(r-4.4)MRCorge_0.1.0.zip(r-4.3)
MRCorge_0.1.0.tgz(r-4.5-any)MRCorge_0.1.0.tgz(r-4.4-any)MRCorge_0.1.0.tgz(r-4.3-any)
MRCorge_0.1.0.tar.gz(r-4.5-noble)MRCorge_0.1.0.tar.gz(r-4.4-noble)
MRCorge_0.1.0.tgz(r-4.4-emscripten)MRCorge_0.1.0.tgz(r-4.3-emscripten)
MRCorge.pdf |MRCorge.html✨
MRCorge/json (API)

# Install 'MRCorge' in R:
install.packages('MRCorge', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/zhwm/mrcorge/issues

Pkgdown site:https://zhwm.github.io

On CRAN:

Conda:

3.60 score 2 stars 4 scripts 3 exports 116 dependencies

Last updated 5 months agofrom:f2464f6e07. Checks:1 OK, 7 WARNING. Indexed: no.

TargetResultLatest binary
Doc / VignettesOKFeb 19 2025
R-4.5-winWARNINGFeb 19 2025
R-4.5-macWARNINGFeb 19 2025
R-4.5-linuxWARNINGFeb 19 2025
R-4.4-winWARNINGFeb 19 2025
R-4.4-macWARNINGFeb 19 2025
R-4.3-winWARNINGFeb 19 2025
R-4.3-macWARNINGFeb 19 2025

Exports:mrcorgeplot_mrcorgeQstatistic

Dependencies:askpassbase64encbitbit64bootbslibcachemclicliprcodetoolscolorspaceCompQuadFormcowplotcpp11crayoncrosstalkcurldata.tabledigestdplyrevaluatefansifarverfastmapfontawesomeforeachfsgenericsggplot2glmnetglueGPArotationgridExtragtablehighrhmshtmltoolshtmlwidgetshttrieugwasrisobanditeratorsjquerylibjsonliteknitrlabelinglaterlatticelazyevallifecyclelme4magrittrMASSmathjaxrMatrixmemoisemetametadatmetaformgcvmimeminqamnormtmr.rapsMRMixMRPRESSOmunsellnlmenloptrnortestnumDerivopensslpbapplypillarpkgconfigplotlyplyrprettyunitsprogresspromisespsychpurrrR6RadialMRrappdirsrbibutilsRColorBrewerRcppRcppEigenRdpackreadrreformulasreshape2rlangrmarkdownsassscalesshapestringistringrsurvivalsystibbletidyrtidyselecttinytexTwoSampleMRtzdbutf8vctrsviridisLitevroomwithrxfunxml2yaml

Negative control example: HDL->CAD

Rendered fromHDL_CAD.Rmdusingknitr::rmarkdownon Feb 19 2025.

Last update: 2024-07-17
Started: 2024-07-17