Package: MRAID
Type: Package
Title: MRAID(Mendelian Randomization with Automated Instrument
        Determination)
Version: 1.0
Date: 2021-06-05
Author: Zhongshang Yuan and Lu Liu
Maintainer: Zhongshang Yuan <yuanzhongshang@sdu.edu.cn>
Description: MRAID is an R package for efficient statistical inference
        of two-sample Mendelian Randomization. MRAID takes GWAS summary
        statistics as inputs to estimate causal effects of one trait on
        another.  MRAID is able to model an initial set of candidate
        SNP instruments that are in high LD with each other and perform
        automated instrument selection to identify suitable SNPs to
        serve as instrumental variables. MRAID simultaneously accounts
        for both uncorrelated and correlated horizontal pleiotropy,
        relies on a scalable sampling-based inference algorithm to
        perform numerical integration, circumventing the difficulty in
        likelihood function, leading to calibrated p-values that enable
        reasonably large-scale exposure screening.
License: GPL-3
Imports: Rcpp (>= 1.0.6)
LinkingTo: Rcpp, RcppArmadillo, RcppDist
RoxygenNote: 7.1.1
NeedsCompilation: yes
Packaged: 2026-05-28 06:00:59 UTC; root
Repository: https://mrcieu.r-universe.dev
Date/Publication: 2023-02-12 13:19:48 UTC
RemoteUrl: https://github.com/yuanzhongshang/MRAID
RemoteRef: HEAD
RemoteSha: 87692470047baeb0061f48c7f316fe11c6fcdad7