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title: 'MRAPSS: The MRAPSS package implement the MR-APPSS approach to test for the
  causal effect of an exposure on a outcome disease.'
version: 0.0.0.9000
doi: 10.32614/CRAN.package.MRAPSS
abstract: The MRAPSS package implement the MR-APPSS approach to test for the causal
  effects between an exposure and a outcome disease. The MR-APPSS is a unified approach
  to Mendelian Randomization accounting for polygenicity, pleiotropy and sample structure
  using genome-wide summary statistics. Specifically, MR-APPSS uses a background-foreground
  model to characterize both SNP-exposure effects and SNP-outcome effects estimates,
  where the background model accounts for confounding from genetic correlation and
  sample structure and the foreground model captures the valid signal for causal inference.
authors:
- family-names: HU
  given-names: Xianghong
  email: maxhu@ust.hk
  orcid: https://orcid.org/0000-0001-5260-3936
repository: https://mrcieu.r-universe.dev
commit: ad5827e4f121f26a0ec63874c2f2b395ff7debf9
contact:
- family-names: HU
  given-names: Xianghong
  email: maxhu@ust.hk
  orcid: https://orcid.org/0000-0001-5260-3936