Package: MRBEE
Type: Package
Title: Mendelian Randomization using Bias-Corrected Estimating Equation
        and Iterative Pleiotropy Testing
Version: 1.0.0
Authors@R: 
    c(person("Noah", "Lorincz-Comi", email = "njl96@case.edu", role = c("aut", "cre"),
      comment = c(ORCID = "0000-0002-0517-2499")),
      person("Yihe", "Yang", email = "yxy1234@case.edu", role = c("aut"),
      comment = c(ORCID = "0000-0001-6563-3579")))
Description: This package performs multivariate Mendelian
        randomization. It is characterized by the removal of
        measurement error bias caused by the estimation error of GWAS
        effect size estimates using an unbiased estimating function in
        measurement error analysis. It also utilizes a pleiotropy test
        to dynamically detect and remove potential pleiotropy, making
        the causal effect robust to pleiotropy.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Depends: R (>= 4.1.0),
Imports: MASS, data.table, FDRestimation, Matrix
RoxygenNote: 7.3.3
LazyDataCompression: xz
Suggests: testthat (>= 3.0.0)
Repository: https://mrcieu.r-universe.dev
Date/Publication: 2026-05-16 02:35:38 UTC
RemoteUrl: https://github.com/noahlorinczcomi/MRBEE
RemoteRef: HEAD
RemoteSha: 07c060cac5e8c831dc3adfa2b9f8b1f4fdb04db3
NeedsCompilation: no
Packaged: 2026-06-15 10:56:22 UTC; root
Author: Noah Lorincz-Comi [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-0517-2499>),
  Yihe Yang [aut] (ORCID: <https://orcid.org/0000-0001-6563-3579>)
Maintainer: Noah Lorincz-Comi <njl96@case.edu>