Package: MRCorge
Title: Mendelian Randomization based on the core gene hypothesis for
        polygenic exposures
Version: 0.1.0
Authors@R: 
    c(person(given = "Wenmin", 
           family = "Zhang", 
           role = c("aut", "cre"), 
           email = "wenmin.zhang@mail.mcgill.ca"),
      person(given = "Tianyuan",
           family = "Lu",
           role = c("aut"),
           email = "tianyuan.lu@wisc.edu"))
Description: This package performs Mendelian Randomization (MR)
        analyses based on the core gene hypothesis for polygenic
        exposures. MR CORGE identifies a small number of putative core
        instruments that are more likely to affect genes with a direct
        biological role in an exposure and obtains causal effect
        estimates based on these instruments, thereby reducing the risk
        of horizontal pleiotropy.
Depends: R (>= 3.5.0)
Imports: ggplot2, TwoSampleMR
License: CC-BY-NC-ND 4.0
URL: https://github.com/zhwm/MRCORGE, https://zhwm.github.io/MRCorge/
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.1
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
Remotes: MRCIEU/TwoSampleMR
Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libssl-dev
Repository: https://mrcieu.r-universe.dev
Date/Publication: 2024-10-19 19:11:47 UTC
RemoteUrl: https://github.com/zhwm/MRCorge
RemoteRef: HEAD
RemoteSha: f2464f6e0709da135cce7d258baf723ec247f14c
NeedsCompilation: no
Packaged: 2026-06-24 10:42:11 UTC; root
Author: Wenmin Zhang [aut, cre],
  Tianyuan Lu [aut]
Maintainer: Wenmin Zhang <wenmin.zhang@mail.mcgill.ca>