{"entrez_gene_symbol":"A2M","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"A2M","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"A2M","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"A2M","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"A2M","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AADAT","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AAMP","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AAMP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AAMP","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCA1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCA1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCA1","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCA1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCA1","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCA1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCA4","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCB1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC8","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC8","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCC8","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCC8","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABCC8","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCC8","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC8","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ABCC8","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABCC9","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABCC9","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABCC9","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCC9","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABCD1","MeSH1":"adrenoleukodystrophy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABCG2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCG4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCG5","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABCG8","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"fibrosarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABL1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABL1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABL1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABL1","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABL1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ABL1","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ABL1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACACA","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACACA","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACACA","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACACB","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACACB","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACACB","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"coronavirus infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACE","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACE","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACE","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACE","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"lipodystrophy","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACE","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"picornaviridae infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"proteinuria","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACE","MeSH1":"west nile fever","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACE2","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACHE","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACHE","MeSH1":"dementia, vascular","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"down syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"drug toxicity","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"lewy body disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"urinary retention","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACHE","MeSH1":"xerostomia","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACLY","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACLY","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACPP","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACPP","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACPP","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ACR","MeSH1":"herpesviridae infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACR","MeSH1":"papilloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ACR","MeSH1":"reproductive tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVR1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACVR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ACVR2A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ACVR2B","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ACVR2B","MeSH1":"muscular atrophy","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ACVRL1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"lesch-nyhan syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"leukemia, hairy cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADA","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADA","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADA","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADA","MeSH1":"severe combined immunodeficiency","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADAM10","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADAM10","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM10","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM10","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM10","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM10","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM10","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM15","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM17","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM33","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM33","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM33","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADAM9","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM9","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM9","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAM9","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS13","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS13","MeSH1":"purpura, thrombotic thrombocytopenic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADAMTS4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS4","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS4","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS5","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS5","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADAMTS8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADCY5","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADCYAP1R1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADCYAP1R1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADIPOQ","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADIPOQ","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADIPOQ","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADIPOQ","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADIPOQ","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADIPOQ","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADK","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADK","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADK","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADK","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADM","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADM","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADM","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADNP","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADNP","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADNP","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADNP","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADNP","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADNP","MeSH1":"supranuclear palsy, progressive","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA1","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA1","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"edema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"edema, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"tachycardia, supraventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"tachycardia, ventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA1","MeSH1":"yersinia infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"akathisia, drug-induced","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"anthrax","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2A","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA2B","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADORA3","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"dysuria","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"polyuria","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"prostatitis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"tetralogy of fallot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"urinary calculi","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"urinary retention","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1A","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"tetralogy of fallot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1B","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"tetralogy of fallot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA1D","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"anxiety, separation","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"retinal detachment","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2A","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2B","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRA2C","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"sarcopenia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"tachycardia","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"tachycardia, supraventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"tachycardia, ventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRB1","MeSH1":"ventricular fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"exophthalmos","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"hyperthyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"tachycardia, supraventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"tachycardia, ventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB2","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"urinary calculi","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB2","MeSH1":"ventricular fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB3","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB3","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRB3","MeSH1":"urinary calculi","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ADRB3","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ADRBK1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AFP","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGPAT2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGRN","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGRN","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGRN","MeSH1":"sarcopenia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AGRP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGRP","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGT","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AGTR1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"AGTR1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AGTR1","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"AGTR1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AGTR1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AGTR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGTR2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AGTR2","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AGTR2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AGTR2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AGTR2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AGTR2","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AGTR2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AGXT","MeSH1":"hyperoxaluria","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AGXT","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AHCY","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AHCY","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AHCY","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AHCY","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AHCY","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AHCY","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AHCY","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AHR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AIFM1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AIFM1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"diabetic cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"polycystic ovary syndrome","MeSH2":"Neoplasms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AKR1B1","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKR1C3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AKT1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKT2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AKT2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AKT3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALAS1","MeSH1":"porphyrias","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ALB","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALB","MeSH1":"hypoalbuminemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALB","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALCAM","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALCAM","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALDH1A1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ALDH1A1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"ALDH2","MeSH1":"alcohol-induced disorders, nervous system","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALDH2","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ALK","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ALK","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALK","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX12","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX15","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"ALOX5","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"nasal polyps","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ALOX5","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5AP","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ALOX5AP","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5AP","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5AP","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5AP","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5AP","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ALOX5AP","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALOX5AP","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ALPL","MeSH1":"hypophosphatasia","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AMD1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AMD1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AMHR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AMHR2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AMOT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AMOT","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AMPD1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AMY2A","MeSH1":"exocrine pancreatic insufficiency","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AMY2A","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AMY2A","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ANG","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANGPT2","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANGPTL4","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANPEP","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ANTXR1","MeSH1":"anthrax","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"ANTXR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANXA5","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ANXA5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANXA5","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ANXA5","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AOC3","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"amyloidosis","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APCS","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APEX1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APH1A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APH1A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"aortic valve stenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOA1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APOA2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APOA4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APOB","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APOB","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOB","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"APOB","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOBEC3G","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOBEC3G","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOBEC4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOC3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"APOC3","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APOC3","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOE","MeSH1":"subarachnoid hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APOF","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"amyloidosis","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"down syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"APP","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AQP2","MeSH1":"diabetes insipidus","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"addison disease","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"dermatitis, seborrheic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"fatigue syndrome, chronic","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"hirsutism","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"hypogonadism","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"muscular atrophy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"polycystic ovary syndrome","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"prostatitis","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"sarcopenia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"turner syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AR","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AREG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ARG1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ARG1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ARG1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ARG1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ARG1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ARG1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ARG1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ARG1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ARG2","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ARG2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ARSA","MeSH1":"leukodystrophy, metachromatic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ARSB","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ARSB","MeSH1":"mucopolysaccharidosis vi","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ARSB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ASAH1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ASAH1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ASIC1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ASIC1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ASIC1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ASIC1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ASIC3","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ASIC3","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ASIC3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ASIC3","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ASPH","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ASPH","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ASPH","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATF4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATF4","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATF4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATIC","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATIC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATM","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATM","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATOH1","MeSH1":"hearing loss","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"drug toxicity","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"plant poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP1A1","MeSH1":"pre-eclampsia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP2A2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP2A2","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ATP2A2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"helicobacter infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP4A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ATP4A","MeSH1":"zollinger-ellison syndrome","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ATP7B","MeSH1":"hepatolenticular degeneration","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ATR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKA","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKB","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AURKC","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVP","MeSH1":"diabetes insipidus","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"brain edema","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"hepatorenal syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"hyponatremia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"infertility, male","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"premenstrual syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1A","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"brain edema","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"hepatorenal syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR1B","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"brain edema","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"diabetes insipidus","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR2","MeSH1":"edema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"AVPR2","MeSH1":"edema, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR2","MeSH1":"enuresis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"hepatorenal syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"hyponatremia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR2","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"nephrotic syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"polyuria","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"AVPR2","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AVPR2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"AXL","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"B2M","MeSH1":"amyloidosis","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"B2M","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"B2M","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"B2M","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"B2M","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"B2M","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"B4GALT2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"B4GALT2","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"B4GALT2","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BACE1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BACE1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BACE1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BACE1","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BACE1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BAX","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BAX","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BAX","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BAX","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BAX","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BBOX1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"BBOX1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"BBOX1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCAP31","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BCAT1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCHE","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BCHE","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCHE","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BCHE","MeSH1":"drug toxicity","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BCHE","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCHE","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BCL2","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCL2L1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BCL6","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCL9","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BCR","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BCR","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BCR","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BCR","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BCR","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BCR","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BCR","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"angioedema","MeSH2":"Cardiovascular Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"angioedemas, hereditary","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"capillary leak syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"systemic inflammatory response syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BDKRB2","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BEST1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BGLAP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BGN","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BGN","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC3","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BIRC5","MeSH1":"thymus neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BMP1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BMP1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BMP2","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BMP2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BMP2","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BMP2","MeSH1":"osteonecrosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BMP2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BMP4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BMP7","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BMP7","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BMP7","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BMP7","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BMP7","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BMP7","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BMP7","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BMX","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"bacterial infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"ear diseases","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"eye infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"impetigo","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"intraabdominal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"meningococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BPI","MeSH1":"staphylococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BRAF","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BRAF","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BRAF","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"sarcoma, synovial","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"BRAF","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRAF","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRCA1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BRCA1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BRCA2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRCA2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRD3","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD3","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRD4","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BRS3","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BRS3","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BSCL2","MeSH1":"lipodystrophy","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BSCL2","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BSG","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"BSG","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BST2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BST2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BST2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"agammaglobulinemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"BTK","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"C1S","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C1S","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C3","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C3","MeSH1":"anemia, hemolytic, autoimmune","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"C3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"C3","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"C3","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"C3","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"C3AR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"C5","MeSH1":"antiphospholipid syndrome","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"glomerulonephritis, membranoproliferative","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"guillain-barre syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"hemolytic-uremic syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"C5","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"hereditary sensory and motor neuropathy","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"C5AR1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CA12","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CA2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CA2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CA2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CA2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CA2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CA2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CA2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CA2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CA2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CA9","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CA9","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CA9","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CA9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CA9","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CACNA1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1A","MeSH1":"dementia, vascular","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1B","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"enuresis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"fissure in ano","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"subarachnoid hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"tachycardia, supraventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"CACNA1C","MeSH1":"ventricular fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1D","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1E","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"hemiplegia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA1G","MeSH1":"vertigo","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"complex regional pain syndromes","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"epilepsy, tonic-clonic","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNA2D1","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CACNB3","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CAD","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"dwarfism","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"osteitis deformans","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CALCA","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"cerebral palsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CALCR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CALCR","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CALCR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CALCR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"osteitis deformans","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CALCR","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CALCR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CALCR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALCRL","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CALM1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CALR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAPN1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAPN1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAPN2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAPN2","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAPRIN1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CARD16","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP2","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP2","MeSH1":"optic neuropathy, ischemic","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP3","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP6","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP6","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"hepatitis, viral, human","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP8","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASP9","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASR","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CASR","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CASR","MeSH1":"hyperparathyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CASR","MeSH1":"hypocalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CASR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CASR","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CAT","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAT","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAT","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAT","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAT","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAT","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CAT","MeSH1":"vitiligo","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CBL","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CBL","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CBLB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CBS","MeSH1":"homocystinuria","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCK","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"biliary dyskinesia","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CCKAR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKAR","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CCKBR","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CCKBR","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCKBR","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CCKBR","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"food hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"keratoconjunctivitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL11","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL14","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL14","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL14","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL16","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL17","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL17","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL20","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL22","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL23","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL24","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCL4","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCL5","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNA2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCNB1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNB1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNB1","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNB1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNB1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCNB1","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNB1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCND1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE1","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNE2","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCNG1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"bronchiectasis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR2","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"anaphylaxis","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"gastroenteritis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"keratoconjunctivitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR3","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCR4","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"adrenoleukodystrophy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"hepatitis a","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"herpesviridae infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CCR5","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"rabies","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR5","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCR6","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CCR6","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR6","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR7","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR8","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR8","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR9","MeSH1":"celiac disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR9","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR9","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CCR9","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CCR9","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD14","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD14","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD14","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD14","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD14","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD160","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD160","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD160","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD160","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD163","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD163","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD19","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD1D","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD1D","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD1D","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CD2","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD200","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD200R1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD209","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD209","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD209","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD209","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD209","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"leukemia, hairy cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD22","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD248","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD27","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD27","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD27","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD27","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD274","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD276","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"intraabdominal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD28","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD300LB","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD300LB","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD300LB","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD300LF","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD300LG","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD300LG","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD300LG","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD320","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD33","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CD33","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD33","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD33","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD33","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD34","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"polycystic ovary syndrome","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD36","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD37","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD37","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD38","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD38","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD38","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD38","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD38","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD38","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD38","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"celiac disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"hyperthyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD3E","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"chlamydia infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"gonorrhea","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD4","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"diphtheria","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"tetanus","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40","MeSH1":"whooping cough","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"hyper-igm immunodeficiency syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD40LG","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"alpha 1-antitrypsin deficiency","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"fasciitis, plantar","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CD44","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"tendinopathy","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"tennis elbow","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD44","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CD46","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD46","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD46","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD46","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD47","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD47","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD47","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD47","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD48","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD48","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD48","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD48","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD5","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD52","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"CD55","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD55","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD59","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD59","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD59","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD59","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD6","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"CD63","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD63","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD63","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD63","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD7","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD7","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD7","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD70","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD70","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD70","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD70","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD70","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD70","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD70","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD72","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD74","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD74","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD74","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD74","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD74","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD74","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD74","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD79B","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD79B","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD79B","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD79B","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD79B","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD79B","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD79B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CD80","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CD80","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"liver cirrhosis, biliary","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD80","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD83","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CD86","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CD86","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD86","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CD8A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD8A","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD8A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD8A","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD8A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD8A","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD97","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CD97","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDC25A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDC25B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDC25C","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDC25C","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDC25C","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDC25C","MeSH1":"mouth neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDC25C","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDC25C","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDC25C","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDC7","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDC7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDCP1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH11","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDH11","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH11","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDH11","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDH11","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH11","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH2","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"choroidal neovascularization","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"fibrosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"myopia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDH5","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"uterine cervical dysplasia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK1","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK2","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"eye neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDK4","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK5","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"eye neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK6","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK7","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDK9","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1A","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1B","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1B","MeSH1":"hearing loss","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN1B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"anus neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDKN2A","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CDKN2B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDKN2C","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CDNF","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CDNF","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CEACAM1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEACAM1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CEACAM1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CEACAM5","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEACAM6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEACAM6","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CEACAM6","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CEBPB","MeSH1":"aids dementia complex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEBPB","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEL","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CEL","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CEL","MeSH1":"malabsorption syndromes","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CEL","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CEL","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA1","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA1","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CELA1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA3B","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CELA3B","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CENPE","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CENPE","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CENPE","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CENPE","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CENPE","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CENPE","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CENPE","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CENPE","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CERK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CES2","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CETP","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CETP","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CETP","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CETP","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CETP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CFD","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFD","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CFD","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFH","MeSH1":"glomerulonephritis, membranoproliferative","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFH","MeSH1":"hemolytic-uremic syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFH","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFLAR","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"amino acid metabolism, inborn errors","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CFTR","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"CFTR","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"hemophilia b","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"marfan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"CFTR","MeSH1":"neurofibromatoses","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"pemphigoid, bullous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CFTR","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CGB","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHAT","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHAT","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHAT","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHAT","MeSH1":"essential tremor","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHAT","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHAT","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHDH","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHDH","MeSH1":"movement disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"mouth neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"mouth neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHEK2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHKA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"biliary dyskinesia","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"bradycardia","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"cholangitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"cholecystitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"down syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"enuresis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"fragile x syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"lewy body disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"myopia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"postcholecystectomy syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"sialorrhea","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"supranuclear palsy, progressive","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CHRM1","MeSH1":"xerostomia","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"biliary dyskinesia","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"cholangitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"cholecystitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"enuresis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"postcholecystectomy syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"sialorrhea","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM2","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"biliary dyskinesia","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"cholangitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"cholecystitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"enuresis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"keratoconjunctivitis","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"postcholecystectomy syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"sialorrhea","MeSH2":"Stomatognathic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CHRM3","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM3","MeSH1":"xerostomia","MeSH2":"Stomatognathic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"biliary dyskinesia","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"cholangitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"cholecystitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"enuresis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"postcholecystectomy syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"sialorrhea","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRM4","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRM4","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CHRNA3","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA3","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA3","MeSH1":"leishmaniasis","MeSH2":"Parasitic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNA3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA3","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNA3","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRNA4","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNA6","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNA7","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CHRNB2","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNB4","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CHRNB4","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CHRNB4","MeSH1":"leishmaniasis","MeSH2":"Parasitic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNB4","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CHRNB4","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CHRNB4","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CIITA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCA1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CLCA1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CLCA1","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CLCA1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CLCA1","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CLCA1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CLCN2","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"hypertension, portal","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CLCN2","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"spinal stenosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLCN2","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLDN3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLDN4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLDN4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC12A","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CLEC4M","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC4M","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC4M","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC4M","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC4M","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC4M","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC7A","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC7A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC7A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC9A","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLEC9A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLIP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLIP1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CLU","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLU","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLU","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLU","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CLU","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLU","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CLU","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CLU","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"pemphigus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CMA1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CMKLR1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CMKLR1","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNGB3","MeSH1":"color vision defects","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR1","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"muscle spasticity","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR1","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR2","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNR2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNR2","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CNTFR","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"color vision defects","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"telangiectasis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CNTFR","MeSH1":"usher syndromes","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"ascites","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"central nervous system neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"pleural effusion, malignant","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL18A1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL1A1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL2A1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"COL2A1","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"COL2A1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"COL2A1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"COL2A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL3A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A3","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A3","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A3BP","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COL4A5","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"COL5A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COMT","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COMT","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"COMT","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"COMT","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"COMT","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COMT","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"COPS5","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COPS5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"COQ7","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"COQ7","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CPB2","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CPB2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CPB2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CPB2","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CPB2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CPB2","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CPS1","MeSH1":"hyperammonemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CPT1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"cardiomyopathy, hypertrophic","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CPT1A","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CPT2","MeSH1":"cardiomyopathy, hypertrophic","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CPT2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"anthrax","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"glomerulonephritis, membranoproliferative","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"staphylococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CR1","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRAT","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRAT","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRAT","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CRAT","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CRAT","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRAT","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CREB1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CREB1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHBP","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHBP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CRHR1","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"brain edema","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CRHR1","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRHR1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"anorexia nervosa","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CRHR2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"brain edema","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRHR2","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CRP","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"respiratory distress syndrome, newborn","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CRP","MeSH1":"systemic inflammatory response syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"aspergillosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"cryptococcosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF1R","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"agranulocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"escherichia coli infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"leukopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RA","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF2RB","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CSF3","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CSF3","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"leukopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CSF3R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CSF3R","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSF3R","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CSNK1A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK1D","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK1D","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSNK1D","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSNK1E","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSNK1E","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSNK1G1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK1G2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK1G3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"giant lymph node hyperplasia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSNK2A1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CSPG4","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSPG4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSPG4","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CSPG4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSPG4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CSPG4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTAG1B","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTF1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTF1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTF1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTF1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"proteinuria","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTGF","MeSH1":"tissue adhesions","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CTLA4","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTLA4","MeSH1":"urogenital neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTNNB1","MeSH1":"adenomatous polyposis coli","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CTNNB1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTNNB1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTNNB1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTNNB1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTNNB1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTNNB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTNNB1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTPS1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTPS1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSB","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSC","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSD","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSD","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSD","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSF","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSF","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSF","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSF","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSF","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSF","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSF","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"alpha 1-antitrypsin deficiency","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"disseminated intravascular coagulation","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"pulmonary emphysema","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSG","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSH","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CTSK","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSL1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSL2","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSL2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSL2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CTSS","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CUBN","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CUBN","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CUBN","MeSH1":"anemia, pernicious","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CUBN","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CUBN","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CUBN","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CUBN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CUBN","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"liver cirrhosis, biliary","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCL10","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCL12","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL13","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCL13","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCL16","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL9","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCL9","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"pemphigoid, bullous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"pemphigoid, bullous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR2","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"adrenoleukodystrophy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"hepatitis a","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"herpesviridae infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"rabies","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR4","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CXCR5","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CXCR6","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCR7","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CXCR7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYBA","MeSH1":"granulomatous disease, chronic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYBB","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CYBB","MeSH1":"granulomatous disease, chronic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYBB","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CYBB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYBB","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP11B1","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"endomyocardial fibrosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"hyperaldosteronism","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CYP11B2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP17A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP17A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP17A1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP17A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"gynecomastia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"hypogonadism","MeSH2":"Endocrine System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"puberty, precocious","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"urinary retention","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP19A1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP1A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP1A1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP1A1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP1A1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP1A1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP1A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP1A1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP1A2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP1B1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP1B1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP1B1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP1B1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP1B1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP1B1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP24A1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CYP24A1","MeSH1":"hyperparathyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CYP24A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP24A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP24A1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"CYP24A1","MeSH1":"rickets","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP26A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP26A1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP26A1","MeSH1":"ichthyosis","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP26A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP26A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP26A1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP26A1","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP27B1","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP27B1","MeSH1":"hyperthyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP27B1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP27B1","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP2A6","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP2B6","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP2B6","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP2B6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP2B6","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP2B6","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP2C8","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CYP2C8","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CYP3A4","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP3A4","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYP3A4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CYP51A1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP51A1","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"CYP7A1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP7A1","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP7A1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP7A1","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP7A1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP7A1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYP7B1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYP7B1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYR61","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYR61","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"rhinitis, allergic, perennial","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"sinusitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"CYSLTR1","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DAG1","MeSH1":"cardiomyopathy, dilated","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DAG1","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DAG1","MeSH1":"muscular dystrophies, limb-girdle","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DAG1","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DAO","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DAO","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DAO","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DAO","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DAO","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DAO","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DBC1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"phenylketonurias","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DBH","MeSH1":"spinocerebellar ataxias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DBH","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DCC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DCK","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DCK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DCK","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DCLRE1C","MeSH1":"severe combined immunodeficiency","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DCN","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DCN","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DCN","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DCN","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DCPS","MeSH1":"muscular atrophy, spinal","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DCT","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DCT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDC","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DDC","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDC","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDC","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDC","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DDC","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDC","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DDC","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DDIT4","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DDIT4","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDIT4","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DDIT4","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DDIT4","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDIT4","MeSH1":"pulmonary emphysema","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DDIT4","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DDR2","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DDX5","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DDX5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DDX5","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DDX5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DEAF1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DEFB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DEFB1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DGAT1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DGAT1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DGAT1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DGAT1","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DGAT1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DGAT1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DGAT1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DGAT2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DGAT2","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHFR","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHFR","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHFR","MeSH1":"bacterial infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHFR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHFR","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHFR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHFR","MeSH1":"neuroectodermal tumors, primitive","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"pneumococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHFR","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHFR","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHODH","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHODH","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DHODH","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHODH","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHPS","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DHPS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DIABLO","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DIABLO","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DIABLO","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DIABLO","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DIABLO","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DIABLO","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DKK1","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DKK1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DKK1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DKK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DKK1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DKK2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DKK2","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DKK2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DLC1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DLK1","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DLL4","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DLL4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DLL4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DLL4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DLL4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DLL4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"amino acid metabolism, inborn errors","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"cardiomyopathy, dilated","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"hemophilia b","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"marfan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"muscular dystrophies, limb-girdle","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"DMD","MeSH1":"neurofibromatoses","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"pemphigoid, bullous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DMD","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DMPK","MeSH1":"myotonic dystrophy","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DNASE1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNASE1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DNASE1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNASE1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNASE1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"DNMT1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DNMT1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DNMT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DNMT1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DOT1L","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DOT1L","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DOT1L","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DOT1L","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DOT1L","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DPP4","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DPP4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP4","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP8","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DPP8","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPP9","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"hand-foot syndrome","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYD","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DPYSL2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYSL2","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DPYSL2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DPYSL2","MeSH1":"epilepsy, tonic-clonic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DPYSL2","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYSL2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYSL2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DPYSL2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"dementia, vascular","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"impulse control disorders","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"lesch-nyhan syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD1","MeSH1":"vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"amenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"central nervous system neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"conduct disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"dementia, vascular","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"galactorrhea","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"postoperative nausea and vomiting","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"rett syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD2","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD2","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD3","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"binge-eating disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD3","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD3","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD3","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD3","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD3","MeSH1":"rett syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD3","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD3","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"anorexia nervosa","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD4","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD4","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD4","MeSH1":"rett syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"DRD4","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD4","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"conduct disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"impulse control disorders","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"lesch-nyhan syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DRD5","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"DSG3","MeSH1":"pemphigus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DUSP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DUSP22","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DUT","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DUT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"DYRK1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DYRK1A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DYRK1A","MeSH1":"down syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DYRK1A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DYRK1A","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"DYRK3","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"DYSF","MeSH1":"muscular dystrophies, limb-girdle","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"E2F1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EAF2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EBP","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EBP","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EBP","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EBP","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EBP","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"pre-eclampsia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ECE1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDA","MeSH1":"ectodermal dysplasia","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDIL3","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDIL3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDIL3","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDN1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDN1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDN1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"hepatorenal syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"EDNRA","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"pre-eclampsia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"subarachnoid hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EDNRA","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"vasospasm, intracranial","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRA","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"hepatorenal syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EDNRB","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"pre-eclampsia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"subarachnoid hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EDNRB","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EDNRB","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"leishmaniasis","MeSH2":"Parasitic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"staphylococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF1A1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"ascites","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"leukemia, hairy cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EEF2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"pseudomonas infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EEF2K","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EFNB2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGF","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGF","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGF","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"EGF","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGF","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFL6","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFL7","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFL7","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFL7","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFL7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"neuroectodermal tumors, primitive","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"thymus neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EGFR","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"urogenital neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGFR","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGLN1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGLN2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EGLN3","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EGR1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EIF2AK2","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF2AK2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF2AK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EIF2AK2","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EIF2S1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF4E","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EIF4E","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EIF4E","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EIF5A","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELAC2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"alpha 1-antitrypsin deficiency","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ELANE","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"bronchiectasis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"disseminated intravascular coagulation","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"pulmonary emphysema","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ELANE","MeSH1":"systemic inflammatory response syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ELAVL1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ELOVL6","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"anus neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENG","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENOX2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ENPEP","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ENPEP","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ENPEP","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ENPEP","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ENTPD1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPAS1","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPAS1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPAS1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"ascites","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"EPCAM","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPCAM","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA3","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA3","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHA3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EPHA3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPHA4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHB4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPHX2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHX2","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPHX2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EPO","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPO","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPO","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EPO","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPO","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPO","MeSH1":"thalassemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPO","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"EPOR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"EPOR","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"cerebral hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"friedreich ataxia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"mitochondrial diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EPOR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"anthrax","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"ascites","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ERBB2","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ERBB2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"ERBB2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"coronavirus infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"cytomegalovirus infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"epstein-barr virus infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ERBB2","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"mouth neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ERBB2","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"smallpox","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ERBB2","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB2","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB3","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERBB4","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERCC1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ERN1","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERN1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ERVW-1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ERVW-1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"dermatitis, seborrheic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"gynecomastia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"hirsutism","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"hypogonadism","MeSH2":"Endocrine System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"infertility, male","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"mastodynia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"menorrhagia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"polycystic ovary syndrome","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"premenstrual syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"turner syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ESR1","MeSH1":"vaginitis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ESR2","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESR2","MeSH1":"prostatitis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESRRA","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ESRRB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRB","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRB","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRG","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ESRRG","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EWSR1","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EXOG","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EXOG","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EXOG","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EXOG","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"EXOG","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"EZH2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EZH2","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EZH2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"EZH2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"disseminated intravascular coagulation","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"hemophilia b","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F10","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"thrombophlebitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F10","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F11","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F11","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F11","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F11","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F11R","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F11R","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F11R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F11R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F11R","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F12","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F12","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F12","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F13A1","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F13A1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F13A1","MeSH1":"factor xiii deficiency","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F13A1","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"F13A1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"antithrombin iii deficiency","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"disseminated intravascular coagulation","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"hypoprothrombinemias","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"thrombophlebitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"F2R","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F2R","MeSH1":"intervertebral disc degeneration","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F2R","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F2RL3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"celiac disease","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"disseminated intravascular coagulation","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"pneumococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"von willebrand diseases","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"F3","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F5","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"cerebral hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"disseminated intravascular coagulation","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F7","MeSH1":"hemophilia b","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F7","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F7","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F7","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"amino acid metabolism, inborn errors","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F8","MeSH1":"hemophilia b","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"marfan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"F8","MeSH1":"neurofibromatoses","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"pemphigoid, bullous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"F8","MeSH1":"von willebrand diseases","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F9","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"amino acid metabolism, inborn errors","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"hemophilia b","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F9","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"F9","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"marfan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"F9","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"neurofibromatoses","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"pemphigoid, bullous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"F9","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"dermatitis, seborrheic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAAH","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FABP1","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FABP1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FABP4","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FABP4","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FABP4","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FABP5","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FABP5","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAH","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FANCC","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAP","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"hepatitis, viral, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FAS","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASLG","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASN","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FASN","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FASN","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FBP1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FCAR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCAR","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCAR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCER2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FCER2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCER2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FCER2","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCER2","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FCER2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCER2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCER2","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"anemia, hemolytic, autoimmune","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FCGR1A","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR2A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR2A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCGR2B","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FCGR3A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR3A","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FCGR3A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR3A","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR3A","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCGR3A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FCGR3A","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR3B","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR3B","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FCGR3B","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR3B","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGR3B","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCGR3B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FCGR3B","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FCGRT","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCGRT","MeSH1":"pemphigus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FCRL5","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FDFT1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FFAR1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FFAR1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FFAR1","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FFAR1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FFAR2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FFAR2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FFAR2","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FFAR2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FFAR4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FFAR4","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FFAR4","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"afibrinogenemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGA","MeSH1":"intervertebral disc degeneration","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"menorrhagia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGA","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGA","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGA","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"afibrinogenemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGB","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGB","MeSH1":"intervertebral disc degeneration","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"menorrhagia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGB","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGB","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGB","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF18","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF18","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF2","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGF20","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF20","MeSH1":"esophagitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF20","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF20","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF21","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF21","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF21","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGF21","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF23","MeSH1":"hypophosphatemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGF4","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGF4","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF4","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF5","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF5","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF5","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGF8","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGF8","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"hearing loss","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"dwarfism","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"FGFR3","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"FGFR3","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR3","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR4","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGFR4","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR4","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR4","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR4","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGFR4","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR4","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFR4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGFRL1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFRL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGFRL1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGFRL1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"afibrinogenemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGG","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGG","MeSH1":"intervertebral disc degeneration","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"menorrhagia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGG","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGG","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FGG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGG","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FGL2","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FGR","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGR","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FGR","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FIGF","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FKBP1A","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FKBP4","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP4","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP4","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP4","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP8","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FKBP8","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLI1","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT1","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT1","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"sarcoma, synovial","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT3","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT3","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT3","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT3","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT3","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT3LG","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT4","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT4","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT4","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"sarcoma, synovial","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FLT4","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FLT4","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FN1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"central nervous system neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"progeria","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FNTA","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FOLH1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLH1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"FOLR1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"pituitary neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOLR1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FOXA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FOXO1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FOXP3","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FPR2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FPR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FPR2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FPR2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FPR2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FRMD4A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"hypogonadism","MeSH2":"Endocrine System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"FSHR","MeSH1":"infertility, male","MeSH2":"Male Urogenital Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"FSHR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FSHR","MeSH1":"polycystic ovary syndrome","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FSHR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FST","MeSH1":"glycogen storage disease type ii","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FST","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FURIN","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FYN","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"FYN","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"FYN","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"FZD7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"G6PD","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"G6PD","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"G6PD","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"G6PD","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"G6PD","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"G6PD","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"G6PD","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GAA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAA","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GAA","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GAA","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GAA","MeSH1":"glycogen storage disease type ii","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GAA","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAA","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAA","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAB1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAB1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"muscle spasticity","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"stuttering","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"muscle spasticity","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA2","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"stuttering","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA2","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"muscle spasticity","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA3","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"stuttering","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA3","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRA4","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA4","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA4","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA4","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"down syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"muscle spasticity","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GABRA5","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"stuttering","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRA5","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRB2","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRB2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB2","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB2","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB3","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRB3","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB3","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRB3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB3","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRB3","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GABRD","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GABRG2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GABRG2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAD1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAD1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GAD1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GAD1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAD2","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAD2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAD2","MeSH1":"neuronal ceroid-lipofuscinoses","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAD2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAD2","MeSH1":"stiff-person syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GADD45A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALC","MeSH1":"leukodystrophy, globoid cell","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GALNS","MeSH1":"mucopolysaccharidosis iv","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GALR1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GALR1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GALR1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GALR2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GALR2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR3","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR3","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GALR3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GALR3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAPDH","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAPDH","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAPDH","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GAPDH","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAPDH","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GART","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GART","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"neuroectodermal tumors, primitive","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GART","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAS6","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"adenomatous polyposis coli","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GAST","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GAST","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"GAST","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GAST","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GAST","MeSH1":"zollinger-ellison syndrome","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GATA3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GATA3","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GBA","MeSH1":"gaucher disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GBA","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GBA","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GBA","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GBP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"cerebral hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"GCG","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"hypoglycemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GCG","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCGR","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCGR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCGR","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GCGR","MeSH1":"hypoglycemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GCGR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCGR","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GCH1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCH1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCH1","MeSH1":"phenylketonurias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCK","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCK","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GCK","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCK","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GCK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCK","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GCK","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GCNT1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCNT1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCNT1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCNT1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCNT1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCNT1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCNT1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GCNT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GDE1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GDF1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GDF5","MeSH1":"intervertebral disc degeneration","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GDNF","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GDNF","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GDNF","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GDNF","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GDNF","MeSH1":"multiple system atrophy","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GDNF","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GFRA1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GFRA1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GFRA1","MeSH1":"hearing loss","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GFRA1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GFRA3","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GFRA3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GFRA3","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GH1","MeSH1":"dwarfism","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GH1","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GH1","MeSH1":"muscular atrophy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"dwarfism","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"ectodermal dysplasia","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"infertility, male","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"lipodystrophy","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"noonan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"prader-willi syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GHR","MeSH1":"short bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHR","MeSH1":"turner syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHRH","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRH","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRH","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHRH","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHRH","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHRH","MeSH1":"lipodystrophy","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHRH","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHRH","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"GHRHR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"lipodystrophy","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GHRHR","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHRHR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GHRL","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"anorexia nervosa","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"dwarfism","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"lipodystrophy","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"prader-willi syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"sarcopenia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GHSR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GIP","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GIP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GIPR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GIPR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLA","MeSH1":"fabry disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GLA","MeSH1":"glycogen storage disease type ii","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GLA","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GLG1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLG1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLI1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLI2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLO1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GLP1R","MeSH1":"diabetes, gestational","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GLP1R","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GLP2R","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GLP2R","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GLP2R","MeSH1":"enterocolitis, necrotizing","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GLP2R","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GLP2R","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GLP2R","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GLP2R","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GLP2R","MeSH1":"short bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GMFB","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GNAQ","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNB2L1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNB2L1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNB2L1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNB2L1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNE","MeSH1":"myositis, inclusion body","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRH1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRH1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRH1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRH1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRH1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GNRH1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRH1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRH1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"amenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"fibrocystic breast disease","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"gynecomastia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"mastodynia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"paraphilias","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"puberty, precocious","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GNRHR","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GNRHR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GP1BA","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GP1BA","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GP1BA","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GP1BA","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GP6","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GP6","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GP6","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GP6","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GPA33","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GPAM","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPBAR1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GPBAR1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GPBAR1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GPBAR1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPBAR1","MeSH1":"hypertension, portal","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPBAR1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GPBAR1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GPBAR1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPC3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GPC3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GPNMB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPNMB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GPNMB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GPR119","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPR119","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GPR119","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPR119","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GPR119","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GPR119","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GPR142","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GPR183","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPR3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPR39","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPR39","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GPR55","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GPR55","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRAP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRB2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRB2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRB2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRB2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRB2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIA1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"epilepsy, tonic-clonic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIA1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"essential tremor","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"fragile x syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIA1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIA1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIA1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"muscle spasticity","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"respiratory insufficiency","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIA1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIK1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIK1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIK1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIK1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIK1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIK1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"aids dementia complex","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIN1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIN1","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIN1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"dementia, vascular","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"emotions","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIN1","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"epilepsy, tonic-clonic","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"hypoglycemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIN1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"nystagmus, pathologic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIN1","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GRIN1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"tinnitus","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN2A","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRIN2B","MeSH1":"subarachnoid hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRIN2D","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM2","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM3","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM4","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM4","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM4","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM4","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"dystonia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"fragile x syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"movement disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM5","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM7","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRM7","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM7","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRM7","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GRN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRN","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRN","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GRPR","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSG2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"supranuclear palsy, progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GSK3B","MeSH1":"tularemia","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSN","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GSN","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTA1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTP1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTP1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTP1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GSTP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GSTP1","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GSTP1","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCA2B","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"GUCY2C","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"mucopolysaccharidosis vii","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"GUSB","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HAAO","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HAMP","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HAMP","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HAO2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HAS2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HAVCR1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HAVCR1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HBB","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HBB","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBB","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HBB","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HBB","MeSH1":"thalassemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"enterocolitis, necrotizing","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HBEGF","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCAR2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCAR2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"HCAR2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCAR2","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"HCAR2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCAR2","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HCAR2","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HCAR2","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCAR2","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCAR2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCAR2","MeSH1":"nephrotic syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HCAR2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCAR2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCAR3","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCAR3","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCK","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCK","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCK","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCN1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCN1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCN1","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCN1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCN1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCN1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCN2","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCN2","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCN2","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCN2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCN2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCN2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCN3","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCN3","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCN3","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCN3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCN3","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCN3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCN4","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCN4","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCN4","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCN4","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCN4","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HCN4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"binge-eating disorder","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"narcolepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCRTR1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"narcolepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"HCRTR2","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"adenomatous polyposis coli","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HDAC1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"muscular atrophy, spinal","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"thalassemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC10","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC11","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"adenomatous polyposis coli","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HDAC2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"thalassemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"friedreich ataxia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"muscular atrophy, spinal","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC3","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC4","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC6","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDAC8","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDC","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDC","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDC","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HDC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HDC","MeSH1":"urticaria","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HDGFRP3","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HEXA","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HEXA","MeSH1":"sandhoff disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HEXA","MeSH1":"tay-sachs disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HEXB","MeSH1":"sandhoff disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HFE2","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"lymphedema","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HGF","MeSH1":"thromboangiitis obliterans","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HIF1A","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HLCS","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HLCS","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMBS","MeSH1":"porphyrias","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HMGA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HMGB1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"aneurysm","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"aortic valve stenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HMGCR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HMGCR","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HMGCR","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HMGCR","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HMGCR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HMGCR","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HMGCR","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMGCR","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMMR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMOX1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMOX1","MeSH1":"hyperbilirubinemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMOX1","MeSH1":"jaundice","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMOX1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HMOX1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HMOX1","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPD","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPD","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPD","MeSH1":"tyrosinemias","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HPGD","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HPGD","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPGDS","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPGDS","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPGDS","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPGDS","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPGDS","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPGDS","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPGDS","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPN","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPRT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HPSE","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HR","MeSH1":"hirsutism","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRAS","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRAS","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRAS","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRAS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRAS","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRAS","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"conjunctivitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"otitis media","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"respiratory distress syndrome, newborn","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"rhinitis, allergic, perennial","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"urticaria","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HRH1","MeSH1":"vertigo","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"weight gain","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"helicobacter infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"herpes zoster","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"radiodermatitis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HRH2","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HRH2","MeSH1":"zollinger-ellison syndrome","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HRH3","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"cataplexy","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"fatigue syndrome, chronic","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"narcolepsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"otitis media","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"vertigo","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"HRH3","MeSH1":"weight gain","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"conjunctivitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"respiratory distress syndrome, newborn","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HRH4","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HSD11B2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD11B2","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD17B1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HSD17B1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD17B1","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD17B1","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD17B1","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD17B1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD17B1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD17B2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HSD17B3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD17B3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD3B2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HSD3B2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSD3B2","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HSD3B2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"mouth neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"muscular atrophy, spinal","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"neurofibromatoses","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90AA1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSP90B1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90B1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90B1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HSP90B1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSP90B1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HSPA5","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPA8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HSPB1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPB8","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPD1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPD1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPD1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPD1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPD1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPD1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPE1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPE1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HSPE1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HSPE1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPE1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HSPG2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTN3","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTN3","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTN3","MeSH1":"pseudomonas infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTN3","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"dysuria","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"rett syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1A","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1A","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"HTR1B","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"hypothermia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1B","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1B","MeSH1":"vasospasm, intracranial","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1D","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1D","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1D","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1D","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1D","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR1D","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1D","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR1F","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"anorexia nervosa","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2A","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2A","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2B","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"central nervous system neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2B","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2B","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2B","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2B","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2B","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2C","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"HTR2C","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2C","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2C","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"movement disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"HTR2C","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"premenstrual syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2C","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR2C","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR2C","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR3A","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR3A","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR3A","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR3A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR3A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"postgastrectomy syndromes","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"postoperative nausea and vomiting","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR3A","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR3A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR3A","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR3A","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"postgastrectomy syndromes","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"postoperative nausea and vomiting","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR4","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR4","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR5A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR5A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR5A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR5A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR5A","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR6","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR6","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR6","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR7","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"HTR7","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"HTR7","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HTR7","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTR7","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HTT","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HYAL1","MeSH1":"edema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"HYAL1","MeSH1":"herpesviridae infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"keratoconus","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"papilloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"reproductive tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"HYAL1","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IAPP","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IAPP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"cytomegalovirus infections","MeSH2":"Virus Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"picornaviridae infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"pouchitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICAM1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICAM3","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ICAM5","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICMT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICOS","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICOS","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICOS","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ICOSLG","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICOSLG","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ICOSLG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ID1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ID3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ID4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ID4","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IDH1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IDH2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"encephalitis","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDO1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IDS","MeSH1":"mucopolysaccharidosis ii","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IDUA","MeSH1":"granulomatous disease, chronic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IDUA","MeSH1":"mucopolysaccharidosis i","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNA1","MeSH1":"aids dementia complex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"alopecia areata","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"encephalitis","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"epidermolysis bullosa","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"pemphigus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA1","MeSH1":"vitiligo","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNA2","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNA2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"respiratory distress syndrome, newborn","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR1","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"adrenoleukodystrophy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"coronavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"encephalitis","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"fatigue syndrome, chronic","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"guillain-barre syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"hepatitis a","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"hepatitis d","MeSH2":"Virus Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"hepatitis, viral, human","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"herpes zoster","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"herpesviridae infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"keratoconjunctivitis","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"leukemia, hairy cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"measles","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"otitis","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"penile induration","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"picornaviridae infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"polyradiculoneuropathy, chronic inflammatory demyelinating","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"prostatic diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"reproductive tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"respiratory distress syndrome, newborn","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"stomatitis, aphthous","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"uterine cervical dysplasia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNAR2","MeSH1":"west nile fever","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNB1","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"aids dementia complex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"alopecia areata","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"encephalitis","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"epidermolysis bullosa","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"pemphigus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNG","MeSH1":"vitiligo","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"cryptococcosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"granulomatous disease, chronic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"osteopetrosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNGR1","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IFNLR1","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNLR1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IFNLR1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IFNLR1","MeSH1":"picornaviridae infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"rett syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"central nervous system neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"dwarfism","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IGF1R","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"lipodystrophy","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"myotonic dystrophy","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"neuroectodermal tumors, primitive","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"sarcoma, synovial","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"short bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"thymus neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF1R","MeSH1":"urogenital neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"glycogen storage disease type ii","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGF2R","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGFBP2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IGFBP2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IGFBP2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IGFBP3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IGFBP3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"IGFBP3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGFBP3","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGFBP3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IGFBP3","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IGFBP3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IGFBP5","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IGFBP5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IGFBP5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IKBKB","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IKBKE","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL10RA","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL10RA","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL10RA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10RA","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10RA","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL10RA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL10RA","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL10RA","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL11RA","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL11RA","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL11RA","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL11RA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL11RA","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL12A","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12A","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"IL12B","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"liver cirrhosis, biliary","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL12B","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL12B","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"igg deficiency","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB1","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"igg deficiency","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL12RB2","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"eosinophilic esophagitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL13","MeSH1":"urogenital neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL13RA2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL13RA2","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL15","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL15","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL15RA","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL15RA","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL15RA","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL15RA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL15RA","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL15RA","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL15RA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL15RA","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"polymyalgia rheumatica","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17A","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17F","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17F","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17RA","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17RA","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL17RA","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17RA","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL17RA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL17RB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL17RC","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL17RC","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL17RC","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL18R1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"giant lymph node hyperplasia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1A","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"arthritis, gouty","MeSH2":"Musculoskeletal Diseases","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"IL1B","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"cerebral hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"cryopyrin-associated periodic syndromes","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL1B","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"familial mediterranean fever","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"polymyalgia rheumatica","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"scleritis","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1B","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL1R1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL1R1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"cryopyrin-associated periodic syndromes","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL1R1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R1","MeSH1":"thrombophlebitis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"cardiomyopathy, hypertrophic","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"cryopyrin-associated periodic syndromes","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL1R2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"noonan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL1R2","MeSH1":"thrombophlebitis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1RAP","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1RL1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"intervertebral disc displacement","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL1RN","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"cytomegalovirus infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"uterine cervical dysplasia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL20","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL20","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL20","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL20","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL21R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL22RA1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL22RA1","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL22RA1","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL22RA1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL22RA1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL22RA1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"igg deficiency","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL23A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL23R","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23R","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23R","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL23R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL24","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL24","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL24","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL24","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL24","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL24","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL24","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL24","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL27","MeSH1":"adrenoleukodystrophy","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL27","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL27","MeSH1":"herpes zoster","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL27","MeSH1":"herpesviridae infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL27","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL27","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL27","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL27","MeSH1":"rabies","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"ascites","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"bronchiolitis obliterans","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"brucellosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"chlamydia infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"cytomegalovirus infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"hemorrhagic fevers, viral","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"herpes zoster","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"intraabdominal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL2RA","MeSH1":"leprosy","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL2RA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL2RA","MeSH1":"meningitis, viral","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"osteomyelitis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"prostatitis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"reproductive tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"sinusitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"uterine cervical dysplasia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RA","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RB","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RB","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RB","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL2RB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL2RG","MeSH1":"severe combined immunodeficiency","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL31","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL31","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL31","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL31","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL37","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL3RA","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4","MeSH1":"urogenital neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"urticaria","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL4R","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL5","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL5","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL5","MeSH1":"eosinophilic esophagitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL5","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL5","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL5","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL5","MeSH1":"nasal polyps","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL5RA","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL5RA","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL5RA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL5RA","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"fatigue","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"giant lymph node hyperplasia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL6R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL6R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"cardiomyopathy, hypertrophic","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"giant lymph node hyperplasia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL6R","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"noonan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IL6R","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"urticaria","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL6R","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL7","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL7","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL7","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL7","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL7","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL7R","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL7R","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL7R","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL7R","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL7R","MeSH1":"leukoencephalopathy, progressive multifocal","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL7R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"bronchiolitis obliterans","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL8","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL9","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL9R","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL9R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IL9R","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IL9R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ILK","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ILK","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ILK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ILK","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IMPA1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"hantavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"hemorrhagic fevers, viral","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"herpes zoster","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"pemphigus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"respiratory syncytial virus infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH1","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IMPDH2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IMPDH2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"INHBC","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"INPP5D","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INS","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"INS","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"INS","MeSH1":"dwarfism","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INS","MeSH1":"dwarfism, pituitary","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"INSR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"INSR","MeSH1":"diabetes, gestational","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"diabetic cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"INSR","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"mucopolysaccharidosis i","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"INSR","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IRAK1","MeSH1":"barrett esophagus","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IRAK1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IRAK1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IRAK1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IRAK1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IRAK1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IRAK1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IRAK1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"IRAK4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IRAK4","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IRAK4","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IRAK4","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"IRAK4","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IRAK4","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IRS1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IRS1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IRS1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IRS1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IRS1","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"IRS1","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"IRS1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"IRS2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA1","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA10","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA11","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA11","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA2B","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGA4","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGA4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA4","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA5","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGA6","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA7","MeSH1":"cardiomyopathy, dilated","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA7","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA7","MeSH1":"muscular dystrophies, limb-girdle","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGA7","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA9","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA9","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGA9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAD","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAE","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAE","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAE","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAE","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAE","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAE","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"ITGAL","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAM","MeSH1":"aneurysm","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAM","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAM","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAM","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAM","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAM","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGAM","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAM","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGAV","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGAV","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGAV","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAV","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGAX","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGAX","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB1BP2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGB1BP2","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"aneurysm","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB2","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGB2","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB3","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB3","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB3","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB3","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB5","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB6","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB7","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITGB7","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ITGB7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITK","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ITK","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITK","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ITM2B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAG1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAG1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"JAK1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"JAK2","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"JAK3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JAK3","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"JUN","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"JUN","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUN","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"JUND","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA3","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNA5","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA5","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNA5","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCND2","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCND3","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCND3","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCND3","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCND3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCND3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNH2","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"long qt syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"tachycardia, supraventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNH2","MeSH1":"ventricular fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNIP3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ11","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ11","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ11","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ11","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNJ11","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNJ11","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ11","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ2","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ2","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ3","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNJ5","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNJ8","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNK18","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNK9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNMA1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNMB1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNMB1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNMB1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNMB1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNMB1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNMB1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNMB1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNMB1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNN4","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNN4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNN4","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNN4","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNN4","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNN4","MeSH1":"myotonic dystrophy","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNN4","MeSH1":"narcolepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"tachycardia, supraventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ1","MeSH1":"ventricular fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ2","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KCNQ3","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KCNQ4","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KCNQ5","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KDM1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KDM1A","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KDM1A","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KDM1A","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KDM1A","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KDM1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDM1A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KDR","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KDR","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KDR","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"sarcoma, synovial","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KDR","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KDR","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KDR","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KHK","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIF11","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR2DL3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIR3DL2","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KISS1R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KISS1R","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KISS1R","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"sarcoma, synovial","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KIT","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"KIT","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLB","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLB","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLF5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK1","MeSH1":"angioedemas, hereditary","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KLK1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KLK1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KLK1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK1","MeSH1":"vasospasm, intracranial","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK2","MeSH1":"ichthyosis","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK3","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK3","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"KLK3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK3","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"KLK3","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KLK3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"KLK3","MeSH1":"prostatitis","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KLK7","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK7","MeSH1":"netherton syndrome","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK7","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLK7","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KLRB1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KLRB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KLRC1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"KLRK1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KLRK1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KLRK1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KMO","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KMO","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KNG1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KNG1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KNG1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KPNB1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KRAS","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KRAS","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KRAS","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KRAS","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KRAS","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KRAS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"KRAS","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KRAS","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"KRAS","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KRT1","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KRT19","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KRT19","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KRT6A","MeSH1":"pachyonychia congenita","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"KSR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"KSR1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LAG3","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAMB3","MeSH1":"epidermolysis bullosa","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAMC2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAMC2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAMC2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAMC2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAMC2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAMC2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LAP3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LAT","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCAT","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCAT","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LCK","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LCK","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LCK","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LDLR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LDLR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LDLR","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LDLR","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LDLR","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LDLR","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LDLR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEF1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEP","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEP","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"lipodystrophy","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"LEPR","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LEPR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS1","MeSH1":"endomyocardial fibrosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS1","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LGALS2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"LGALS3","MeSH1":"endomyocardial fibrosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LGALS3","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LGALS9","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LGALS9","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"cerebral hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"hypogonadism","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LHCGR","MeSH1":"infertility, male","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"prostatitis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LHCGR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LIFR","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LIFR","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LILRA4","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LILRB3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LILRB3","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LILRB4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LILRB4","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LILRB4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LILRB4","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LILRB4","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LIMK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LIMK2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LIMK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LINGO1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LINGO1","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LINGO1","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LINGO1","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LIPA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LIPA","MeSH1":"wolman disease","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"LIPE","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LIPF","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LIPF","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LNPEP","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LNPEP","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LNPEP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LOX","MeSH1":"endomyocardial fibrosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LOX","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LOX","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LOXL2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LOXL2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LOXL2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LOXL2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LOXL2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LOXL2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LOXL2","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LPAR1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LPAR1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LPAR1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LPAR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPAR1","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LPAR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPAR3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPAR3","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LPAR5","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"bursitis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LPL","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LPL","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LRP1","MeSH1":"hepatitis, viral, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRP1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LRP1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRP2","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRP2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRP2","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRP5","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LRP5","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LRP5","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRP6","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRP6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRP6","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LRP6","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRRK2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRRK2","MeSH1":"down syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LRRK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LRRK2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LSS","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LSS","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTA4H","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTA4H","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTA4H","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTA4H","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTA4H","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTA4H","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTA4H","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LTB4R","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"subarachnoid hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTB4R","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTBR","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTBR","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTBR","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTBR","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTBR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTBR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTBR","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTBR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTC4S","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTC4S","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"clostridium infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"drug toxicity","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"escherichia coli infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"eye infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"pseudomonas infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"staphylococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LTF","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LY75","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LYN","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"LYN","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"LYN","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"LYZ","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"LYZ","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MADCAM1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MADCAM1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MADCAM1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MADCAM1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAF","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAF","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAF","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAF","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAF","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAG","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAG","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAG","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAGEA1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAGEA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAGEA3","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAGEA4","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAN2B1","MeSH1":"alpha-mannosidosis","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MANF","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MANF","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MAOA","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MAOA","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"friedreich ataxia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MAOA","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOA","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"dementia, vascular","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MAOB","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MAOB","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"friedreich ataxia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"multiple system atrophy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MAOB","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAOB","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAP2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"cardiomyopathy, hypertrophic","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"noonan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"thymus neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"cardiomyopathy, hypertrophic","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"noonan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"thymus neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP2K2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K4","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K4","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K5","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K6","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K7","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP2K7","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP3K1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAP3K1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP3K1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP3K1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP3K1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAP3K12","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP3K5","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP3K5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP3K5","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP3K5","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAP3K8","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP4K4","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP4K4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP4K4","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP4K4","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAP4K4","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPK1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK10","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK10","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK10","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK10","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK10","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK10","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK10","MeSH1":"tissue adhesions","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK11","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK11","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK11","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"carcinoma, transitional cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MAPK14","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK14","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK3","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPK3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK8","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPK8","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPK8","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8","MeSH1":"tissue adhesions","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"hearing loss","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK8IP1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK9","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPK9","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPK9","MeSH1":"tissue adhesions","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPKAPK2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPKAPK2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAPKAPK2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPKAPK5","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MAPT","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAPT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPT","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPT","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAPT","MeSH1":"supranuclear palsy, progressive","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MARCKS","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MARCKS","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MARCKS","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MAS1","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MASP2","MeSH1":"hemolytic-uremic syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MASP2","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MASP2","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MAX","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBD2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBL2","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBL2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBL2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBL2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MBL2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBL2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBOAT4","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBP","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MBP","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBP","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MBP","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MBP","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MBP","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MBP","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MBP","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"urticaria","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC1R","MeSH1":"vitiligo","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC2R","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC2R","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC2R","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MC2R","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MC2R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC2R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MC3R","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC3R","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC3R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MC3R","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC3R","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MC4R","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC5R","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC5R","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MC5R","MeSH1":"dermatitis, seborrheic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC5R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MC5R","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MC5R","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MC5R","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCAM","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MCAM","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MCAM","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MCAM","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCAM","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCHR1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCHR1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCHR1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCHR1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCHR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MCHR1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MCL1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MDK","MeSH1":"optic neuropathy, ischemic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MDM2","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MDM4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MELK","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MELK","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MELK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MEN1","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MEN1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MEN1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MEOX2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MET","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"mouth neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"thromboangiitis obliterans","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MET","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MET","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"METAP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"METAP2","MeSH1":"prader-willi syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MFGE8","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MFGE8","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MFGE8","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MFGE8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MFGE8","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MFI2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MFI2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MGEA5","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MGEA5","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MGLL","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"central nervous system neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MGMT","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIA","MeSH1":"intervertebral disc degeneration","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIA","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIA","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIEN1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MIF","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"MKI67","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MKNK1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MKNK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MLANA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"esophagitis, peptic","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"gastritis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MLNR","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MLYCD","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MLYCD","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MME","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"pre-eclampsia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MME","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMEL1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMEL1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMEL1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"ascites","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"bronchiectasis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"epidermolysis bullosa","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MMP1","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"pterygium","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MMP1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP11","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP11","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP11","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP12","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP12","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP12","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP12","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP13","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP13","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP13","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP13","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP13","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP13","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP13","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP14","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP14","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP14","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP14","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"aneurysm","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"infarction","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP2","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP3","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP8","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP8","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP8","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP8","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP8","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP8","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP8","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MMP8","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"bronchiectasis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"epidermolysis bullosa","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MMP9","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MOGS","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MOGS","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MOGS","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MPL","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MPL","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MPL","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MPL","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MPL","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MPL","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MPL","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MPL","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"MPL","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MPO","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MPO","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MPO","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MPO","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MPO","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MPO","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MRGPRD","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MRGPRX1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MS4A1","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MS4A1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MS4A1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MS4A1","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"opsoclonus-myoclonus syndrome","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"pemphigoid, bullous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"MS4A1","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MS4A1","MeSH1":"wegener granulomatosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"MSLN","MeSH1":"ascites","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSLN","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MST1R","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MST1R","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"muscular atrophy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"muscular dystrophies, limb-girdle","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"muscular dystrophy, facioscapulohumeral","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MSTN","MeSH1":"sarcopenia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"MTF1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTF1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTF1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"movement disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"sleep disorders, circadian rhythm","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1A","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"movement disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"sleep disorders, circadian rhythm","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTNR1B","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTOR","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"central nervous system neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTOR","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"hamartoma syndrome, multiple","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTOR","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"lymphangioleiomyomatosis","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTOR","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"neurofibromatoses","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"MTOR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"MTOR","MeSH1":"staphylococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"streptococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"tuberous sclerosis","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTOR","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTOR","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTRNR2L1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTTP","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTTP","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTTP","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"MTTP","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTTP","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MTTP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MTTP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC16","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MUC16","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUC16","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MUC16","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"MUSK","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MXD1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYB","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYB","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYB","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYB","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYC","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYCN","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYD88","MeSH1":"barrett esophagus","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYD88","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYD88","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYD88","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYD88","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"MYD88","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYD88","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYD88","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYLIP","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"MYLK","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYLK","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"MYO7A","MeSH1":"usher syndromes","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NAGLU","MeSH1":"mucopolysaccharidosis iii","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NAIP","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAIP","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAIP","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAIP","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAMPT","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAMPT","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAMPT","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NAMPT","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAMPT","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAMPT","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NAMPT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"NANS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAM1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCAN","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCEH1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCF1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCF1","MeSH1":"granulomatous disease, chronic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCL","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NCOR2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NCR1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NCR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NCR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NEDD4","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NEK3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NELL1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFATC1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFATC1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFATC1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFATC1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFATC1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFATC1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFATC1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"pulmonary emphysema","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"NFE2L2","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"amyloidosis","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"bronchiolitis obliterans","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"coronavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"dermatitis, seborrheic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"hemolytic-uremic syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"hemorrhagic fevers, viral","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"herpesviridae infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"intervertebral disc degeneration","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NFKB1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NFKB1","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKB1","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NFKBIA","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NFKBIA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGF","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"fatigue syndrome, chronic","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"granulomatous disease, chronic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"motor neuron disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NGFR","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NISCH","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NISCH","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NISCH","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NISCH","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NISCH","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NISCH","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NISCH","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NLE1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NLN","MeSH1":"hypothermia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NLN","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NLN","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NLN","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NMBR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NMBR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NMBR","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NMBR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NMBR","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NMBR","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NME1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NMT1","MeSH1":"aspergillosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NMT1","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NMUR1","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NMUR2","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NMUR2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOG","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOG","MeSH1":"myositis ossificans","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOG","MeSH1":"ossification, heterotopic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOP2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS2","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOS3","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOTCH1","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NOTCH1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOTCH1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOTCH2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH2","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH2","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH3","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOTCH3","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOX1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOX1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NOX1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NOX1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOX1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NOX1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NOX4","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NOX4","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NOX4","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NOX4","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NPBWR1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPC1L1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPC1L1","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NPC1L1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NPFFR2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPFFR2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPFFR2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPHS1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NPR1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"infertility, male","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPR1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPR2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NPR2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPR2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NPR2","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NPRL2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPSR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPSR1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY1R","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY2R","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NPY5R","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY5R","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY5R","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NPY5R","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NPY5R","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR1H2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR1H3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"hypertension, portal","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"liver cirrhosis, biliary","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR1H4","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"addison disease","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"adenoviridae infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"ataxia telangiectasia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"blepharitis","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"brain edema","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"chorioretinitis","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"croup","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"dermatitis, seborrheic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"ear diseases","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"eosinophilic esophagitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"erythema multiforme","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"exophthalmos","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"eye infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"gastroenteritis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"hearing loss","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"hyperthyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"impetigo","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"keratoconjunctivitis","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"liver cirrhosis, biliary","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"melanosis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"meniere disease","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"mucocutaneous lymph node syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"nasal polyps","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"nephrotic syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"otitis","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"otitis externa","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"otitis media","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"polymyalgia rheumatica","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"proctitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"retinal vein occlusion","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"rhinitis, allergic, perennial","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"scleritis","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"serum sickness","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"sinusitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"spasms, infantile","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"stomatitis, aphthous","MeSH2":"Stomatognathic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"tendinopathy","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C1","MeSH1":"weight gain","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C2","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"edema, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"NR3C2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR3C2","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NR4A2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NR4A2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR5A1","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR5A1","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NR5A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NRAS","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NRAS","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NRG1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRG1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRG1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRG1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRG2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRG2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRG2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRG2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRIP1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRIP1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRP1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRTN","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRTN","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRTN","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRTN","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NRTN","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NRTN","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NRTN","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NSUN2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTHL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTN1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTN1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK2","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"ear diseases","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NTRK3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"NUAK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"NUP85","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NXNL1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"NXNL1","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OAT","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OCM","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OCM","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"adenomatous polyposis coli","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"barrett esophagus","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"fecal incontinence","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"hirsutism","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"ODC1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ODC1","MeSH1":"uterine cervical dysplasia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OGFR","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"binge-eating disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"complex regional pain syndromes","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRD1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRD1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"drug toxicity","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"emotions","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRD1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"OPRD1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRD1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRD1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRD1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRD1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"binge-eating disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"complex regional pain syndromes","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"drug toxicity","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"impulse control disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRK1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRK1","MeSH1":"urinary retention","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"sleep disorders, circadian rhythm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRL1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"binge-eating disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"bursitis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"complex regional pain syndromes","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"drug toxicity","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"impulse control disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OPRM1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"urinary retention","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OPRM1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"OSM","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OSTN","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"infertility, male","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"OXTR","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OXTR","MeSH1":"postpartum hemorrhage","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"OXTR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX3","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"P2RX3","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"P2RX3","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"P2RX3","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX3","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"P2RX4","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RX7","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"P2RY1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"P2RY12","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY12","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY12","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY12","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RY12","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY12","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY12","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY12","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY12","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY12","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY12","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY12","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY12","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY12","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P2RY2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"rhinitis, allergic, perennial","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"sinusitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"P2RY2","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P2RY2","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"P4HA1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"carcinoma, renal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HA1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HTM","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HTM","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HTM","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"P4HTM","MeSH1":"postoperative complications","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PABPN1","MeSH1":"muscular dystrophy, oculopharyngeal","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PAGE4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PAH","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PAH","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PAH","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PAH","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PAH","MeSH1":"phenylketonurias","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PAH","MeSH1":"spinocerebellar ataxias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PAK1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PAK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PAK4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PARG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARK2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PARK2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARL","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"supranuclear palsy, progressive","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"weight gain","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PARP2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PASD1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PAX2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PAX2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PAX4","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PAX4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PAX6","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PAX6","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PCDHGC3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PCK1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PCK1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PCNA","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PCSK6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PCSK9","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PCSK9","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PCSK9","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PCSK9","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PCSK9","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDCD1LG2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE10A","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE11A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE1A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE1A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"adenomatous polyposis coli","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"barrett esophagus","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE2A","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE3A","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE3A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PDE3A","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE3A","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE3A","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"thromboangiitis obliterans","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE3A","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE3A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE3A","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4A","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4A","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"dementia, vascular","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4B","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4B","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4C","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4C","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE4D","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE4D","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"adenomatous polyposis coli","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"barrett esophagus","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"carcinoma, transitional cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE5A","MeSH1":"gastroparesis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"hypertension, portal","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE5A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDE5A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE5A","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"binge-eating disorder","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7A","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7B","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE7B","MeSH1":"binge-eating disorder","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7B","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7B","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7B","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDE7B","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7B","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE7B","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDE9A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDE9A","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFA","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFB","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFB","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDGFD","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFD","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFD","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"sarcoma, synovial","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRA","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"osteonecrosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"sarcoma, synovial","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"tennis elbow","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDGFRB","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDHA1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDHA1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDHA1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDHA1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDHA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDHA1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDK1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDK1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDPK1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDPK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDPK1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDX1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDX1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDX1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PDYN","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PDYN","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDYN","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDYN","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PDYN","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PDYN","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PF4","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PFKFB3","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PFKFB3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PFKFB3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PGAP2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"myopia","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PGF","MeSH1":"retinal vein occlusion","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGF","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"amenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"mastodynia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"menorrhagia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"premenstrual syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PGR","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"uterine cervical dysplasia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PGR","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PHB","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PHB","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PHB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PHEX","MeSH1":"hypophosphatemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PI3","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIGR","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3C3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"hamartoma syndrome, multiple","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"staphylococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"streptococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CA","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CB","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CD","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIK3CG","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIKFYVE","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIM1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIM2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM3","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM3","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM3","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIM3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PIM3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PIM3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PIN1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PKD2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PKM","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PKM","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PKM","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PKM","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PKM","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PKM","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PKN1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PKN3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PKN3","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PKN3","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PKN3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PKN3","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PKN3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PKN3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"acute chest syndrome","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G10","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G1B","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G1B","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G1B","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G1B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G1B","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G1B","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"acute chest syndrome","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G2A","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G4A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"acute chest syndrome","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G6","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"acute chest syndrome","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLA2G7","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAC1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAC1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAC1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLAT","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLAT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLAT","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PLAT","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLAU","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"porphyrias","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLAU","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLAU","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PLAU","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLAUR","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLEC","MeSH1":"epidermolysis bullosa","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLEC","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLG","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLG","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLG","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PLG","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLIN3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"thymus neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PLK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PLK2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLK3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLN","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLOD1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLOD1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLOD1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLOD1","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PLXDC1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PMEL","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PMEL","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PMEL","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PMEL","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PMEL","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNLIP","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PNLIP","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PNLIP","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PNLIP","MeSH1":"exocrine pancreatic insufficiency","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PNLIP","MeSH1":"flatulence","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PNLIP","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNLIP","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNLIP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PNLIP","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PNLIP","MeSH1":"steatorrhea","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PNMT","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNMT","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNMT","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PNMT","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"lesch-nyhan syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PNP","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"POLA1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"POLA1","MeSH1":"leukemia, hairy cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"POLA1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"meningitis, aseptic","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"POLA1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLA1","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"POLB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"POLB","MeSH1":"leukemia, hairy cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"meningitis, aseptic","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"POLB","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POLB","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POM121","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"POMC","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PON1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PON1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PON1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PORCN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PORCN","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PORCN","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPAN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPARA","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPARA","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPARA","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPARA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARA","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARD","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"PPARG","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PPARG","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"morphine dependence","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"polycystic ovary syndrome","MeSH2":"Neoplasms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPARG","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPBP","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPBP","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"alopecia areata","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPIA","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPIA","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"bronchiolitis obliterans","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPIA","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"keratoconjunctivitis","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPIA","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"nephrotic syndrome","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPIA","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPIA","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPIA","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPIA","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PPIB","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPIB","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPID","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPID","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPID","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPID","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPID","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPID","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPID","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPM1D","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPP2CA","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPP2CA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPP2CA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPP2CA","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPP2CA","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPP2CA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PPP2CA","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PPT1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRAME","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRAME","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRAME","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRAME","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRAME","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRAME","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRAME","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRCP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PREP","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PREP","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PREP","MeSH1":"celiac disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PREP","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PREP","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PREP","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRF1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRG2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKAA1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKACA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKAG3","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKAR1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCA","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCB","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PRKCD","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCD","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"hyperparathyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCE","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCG","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCH","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCH","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCH","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCH","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCH","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCI","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKCQ","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKD1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKDC","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRKG1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRLHR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRLHR","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRLHR","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRLHR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRLR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRMT5","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRMT5","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRMT5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRNP","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRNP","MeSH1":"creutzfeldt-jakob syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRNP","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRNP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"purpura fulminans","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PROC","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PROC","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PROC","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PROK1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PROK2","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PROK2","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PROKR1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PROM1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PROM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PROS1","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PRPH2","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRPH2","MeSH1":"retinitis pigmentosa","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRSS12","MeSH1":"sarcopenia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PRSS50","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRTN3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PRTN3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRTN3","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PRTN3","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PSCA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PSCA","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PSCA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PSCA","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PSEN1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PSEN2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PSENEN","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PSENEN","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PSIP1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PSIP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PSMD10","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"aids dementia complex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"rhinitis, allergic, perennial","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTAFR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTAFR","MeSH1":"urticaria","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTCH1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTCH1","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"central nervous system neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTEN","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTEN","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTEN","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"eosinophilic esophagitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDR2","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGDS","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGDS","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGDS","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGDS","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGER1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER1","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER1","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"hepatitis, viral, human","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"PTGER1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGER1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER1","MeSH1":"thromboangiitis obliterans","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER1","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER2","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER2","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER2","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER2","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER3","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER3","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER3","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER3","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGER3","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGER4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGES","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGFR","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGFR","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"hypotrichosis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGFR","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGFR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"fetal death","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGIR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"osteonecrosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGIR","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"raynaud disease","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGIR","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"spinal stenosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"thromboangiitis obliterans","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGIR","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGIR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"arthritis, gouty","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"bursitis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"diverticulitis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"ductus arteriosus, patent","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"enterocolitis, necrotizing","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"menorrhagia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"proctitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"tendinopathy","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"tennis elbow","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS1","MeSH1":"vulvodynia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"adenomatous polyposis coli","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"arthritis, gouty","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"barrett esophagus","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"bursitis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"diverticulitis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"ductus arteriosus, patent","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"enterocolitis, necrotizing","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"menorrhagia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"proctitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"tendinopathy","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"tennis elbow","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"urinary bladder, neurogenic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTGS2","MeSH1":"vulvodynia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTGS2","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH","MeSH1":"hyperparathyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH","MeSH1":"hypoparathyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"bone cysts","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"hypocalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"hypoparathyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"osteopetrosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTH1R","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTH1R","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTHLH","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTHLH","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTHLH","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTK2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTK6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTK7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTMA","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTMA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTMA","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTMA","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTMA","MeSH1":"hepatitis, viral, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTMA","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTMA","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTMA","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTMA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTMA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTN","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTN","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTP4A3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTP4A3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"anorexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"capillary leak syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"leishmaniasis","MeSH2":"Parasitic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTPN1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTPN1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"leishmaniasis","MeSH2":"Parasitic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTPN11","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN11","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"leishmaniasis","MeSH2":"Parasitic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"PTPN6","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPN6","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPRC","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PTPRC","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTPRF","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTPRG","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTPRJ","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTPRJ","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTPRJ","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PTPRZ1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PVR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PVR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PVR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PVRL1","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PVRL4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PVRL4","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PVRL4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"PVRL4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PVRL4","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"aneurysm","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"PYGL","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PYGO1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"PYY","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"QARS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"QPCT","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"QPCT","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"QPCT","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"QPCT","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAD51","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RAF1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RAF1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAF1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RALBP1","MeSH1":"hand-foot syndrome","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RALBP1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RAMP1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAPGEF3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RAPGEF3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RARA","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RARA","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RARB","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RARB","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RARB","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARG","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RARG","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARG","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RARG","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RARG","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARG","MeSH1":"pulmonary emphysema","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RARG","MeSH1":"uterine cervical dysplasia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARRES2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARRES3","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RARRES3","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RARRES3","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RARRES3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RARRES3","MeSH1":"respiratory syncytial virus infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RARRES3","MeSH1":"west nile fever","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RASSF1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RASSF1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RB1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RB1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RB1","MeSH1":"hearing loss","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RB1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RBBP9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RBP4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RBP4","MeSH1":"diabetic cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REG3A","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"REG3A","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REG3A","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"REG3A","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"REG3A","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"REG3A","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"REG3A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RELA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RELA","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RELA","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"REN","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"REN","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"REST","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RET","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RET","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RET","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RET","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RET","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RET","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RHD","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RHD","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RHD","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RHD","MeSH1":"rh isoimmunization","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RHD","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"vasospasm, intracranial","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RHOA","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RHOC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RIPK2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RIPK3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RLN1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RLN1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RNASE2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASE2","MeSH1":"paramyxoviridae infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASE2","MeSH1":"respiratory syncytial virus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASE2","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASE3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASEL","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASEL","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASEL","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASEL","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASEL","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNASEL","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNPEP","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RNPEP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROBO1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ROBO4","MeSH1":"anthrax","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROBO4","MeSH1":"edema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROBO4","MeSH1":"hemorrhagic fever, ebola","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROBO4","MeSH1":"marburg virus disease","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ROCK2","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RORA","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RORC","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RPA1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RPA1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPA1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RPA1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPA1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RPA1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RPE65","MeSH1":"color vision defects","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPE65","MeSH1":"leber congenital amaurosis","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RPE65","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RPGRIP1","MeSH1":"leber congenital amaurosis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KA2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KA2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RPS6KB1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RRM1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"osteitis deformans","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"pseudomonas infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RRM1","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RRM2","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RRM2","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RS1","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RSPO1","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RSPO1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RSPO1","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RTN4","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"RTN4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RTN4","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RTN4","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RTN4","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RTN4","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RTN4","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RTN4","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RUNX2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RUNX3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RUNX3","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"RXFP1","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"pre-eclampsia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXFP1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXFP2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXFP2","MeSH1":"obstetric labor complications","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXFP2","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXFP2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RXRA","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRA","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"RXRG","MeSH1":"neutropenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RXRG","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RYK","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RYK","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RYK","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RYK","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"RYR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RYR1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RYR1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RYR1","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RYR1","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"RYR2","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"RYR2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"RYR2","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"RYR2","MeSH1":"tachycardia, ventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S100A10","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"S100A4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S100A4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S100A9","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S100A9","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S100A9","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S100A9","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S100A9","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S100A9","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"S100A9","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S100A9","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"hypotension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"S1PR1","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"polyradiculoneuropathy, chronic inflammatory demyelinating","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"S1PR3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"polyradiculoneuropathy, chronic inflammatory demyelinating","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR3","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR4","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR4","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR4","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"S1PR4","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR4","MeSH1":"polyradiculoneuropathy, chronic inflammatory demyelinating","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR4","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"S1PR5","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"optic neuritis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"polyradiculoneuropathy, chronic inflammatory demyelinating","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"S1PR5","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SAG","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SAG","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SAG","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SAT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCAP","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCARB1","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCARB1","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"dermatitis, seborrheic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCD","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"bronchopulmonary dysplasia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"meconium aspiration syndrome","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"nasal polyps","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"pneumococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"respiratory distress syndrome, newborn","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"respiratory syncytial virus infections","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB1A1","MeSH1":"sinusitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCGB2A2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN10A","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN1A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"epilepsies, myoclonic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN1A","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN1A","MeSH1":"epilepsy, tonic-clonic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN1A","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN1A","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN1A","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN1A","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN1A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN1A","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN3A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN3A","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN3A","MeSH1":"epilepsy, tonic-clonic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN3A","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN3A","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN3A","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN3A","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN3A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN3A","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN5A","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SCN5A","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN5A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN5A","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"epilepsy, tonic-clonic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN5A","MeSH1":"essential tremor","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"intellectual disability","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN5A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN5A","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"tachycardia, supraventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"tachycardia, ventricular","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN5A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN5A","MeSH1":"ventricular fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN9A","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"bursitis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"dysmenorrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"dyspareunia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"SCN9A","MeSH1":"erythromelalgia","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"headache","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"infertility, female","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN9A","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SCN9A","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN9A","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCN9A","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"polyuria","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"stomatitis, aphthous","MeSH2":"Stomatognathic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"tendinopathy","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"tinnitus","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"vertigo","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCN9A","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"bronchiectasis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"edema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"edema, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCNN1A","MeSH1":"xerostomia","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SCTR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCTR","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCTR","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCTR","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SCTR","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCTR","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCTR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SCTR","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCTR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCTR","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SCTR","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SDC1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SDC1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"systemic inflammatory response syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELE","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELL","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELP","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SELPLG","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SELPLG","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SELPLG","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SEMA3A","MeSH1":"urogenital neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SEMA4D","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SEMA4D","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"alpha 1-antitrypsin deficiency","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"anthrax","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"bronchiectasis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"herpesviridae infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"pancreatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"pulmonary emphysema","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPINA1","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA4","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINA4","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINB2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINB2","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINB2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"angina, unstable","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"antithrombin iii deficiency","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"atrial fibrillation","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"diabetic foot","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"disseminated intravascular coagulation","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"pressure ulcer","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"thrombophlebitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINC1","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE1","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE2","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINE2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINF1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINF1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINF1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINF1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPINF2","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SERPINF2","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SERPING1","MeSH1":"angioedema","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPING1","MeSH1":"angioedemas, hereditary","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SERPING1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPING1","MeSH1":"capillary leak syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPING1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPING1","MeSH1":"pulmonary embolism","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SERPING1","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SERPING1","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SFRP1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SFRP2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SGIP1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SGPL1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SGPL1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SGSH","MeSH1":"mucopolysaccharidosis iii","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SH3RF1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SHC1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SHC1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SHH","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SHH","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SHH","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SI","MeSH1":"carbohydrate metabolism, inborn errors","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SIGLEC15","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIGLEC15","MeSH1":"osteopetrosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"emotions","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"opioid-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIGMAR1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIK2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIK2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIK2","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIK2","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIK2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIM2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIRPA","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"mitochondrial encephalomyopathies","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"muscular atrophy","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIRT1","MeSH1":"sarcopenia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SIRT2","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIRT2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIRT2","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIRT2","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIRT2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIRT2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIRT2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SIRT2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLAMF6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLAMF7","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLAMF7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC10A2","MeSH1":"cholelithiasis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC10A2","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC10A2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC10A2","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC10A2","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC10A2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC10A2","MeSH1":"liver cirrhosis, biliary","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC10A2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC11A2","MeSH1":"poisoning","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A1","MeSH1":"edema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC12A1","MeSH1":"edema, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC12A1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC12A1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC12A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC12A1","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"edema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"edema, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC12A2","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A3","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC12A3","MeSH1":"bacterial infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC12A3","MeSH1":"edema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC12A3","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC12A3","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC12A3","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC12A5","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC12A5","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC16A1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC16A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC18A2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC18A2","MeSH1":"dystonia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC18A2","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC18A2","MeSH1":"movement disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC18A2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC18A2","MeSH1":"tourette syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC19A1","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC1A1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC1A2","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC22A12","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"SLC22A12","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC22A12","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC25A10","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC25A10","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC25A4","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC27A4","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC2A4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC2A8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC30A8","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC34A3","MeSH1":"hyperphosphatemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC40A1","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC5A1","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC5A1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC5A2","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC5A2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC5A2","MeSH1":"glucose intolerance","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC5A2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC5A2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC5A5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC5A5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC6A1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A11","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A11","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A11","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A11","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A11","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A11","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A2","MeSH1":"vulvodynia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"premenstrual syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"tobacco use disorder","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A3","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"attention deficit disorder with hyperactivity","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"autistic disorder","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"binge-eating disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"bulimia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"cocaine-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"fibromyalgia","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"hyperprolactinemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"narcolepsy","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"neurotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"premenstrual syndrome","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"restless legs syndrome","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"Withdrawn","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"substance-related disorders","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"tinnitus","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SLC6A4","MeSH1":"vulvodynia","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A5","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A5","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A5","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A7","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A9","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A9","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC6A9","MeSH1":"obsessive-compulsive disorder","MeSH2":"Mental Disorders","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC6A9","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC6A9","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC7A5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"essential tremor","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC8A1","MeSH1":"unverricht-lundborg syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC9A1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC9A1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC9A1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC9A3","MeSH1":"apnea","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SLC9A3","MeSH1":"constipation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC9A3","MeSH1":"edema, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SLC9A3","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC9A3","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC9A3","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLC9A3","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLC9A3","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SLPI","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLPI","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLPI","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SLURP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SMN1","MeSH1":"muscular atrophy, spinal","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SMN2","MeSH1":"muscular atrophy, spinal","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"basal cell nevus syndrome","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SMO","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMO","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMPD1","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SMPD1","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SMPD1","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SMPD1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SMPD1","MeSH1":"niemann-pick diseases","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SMPD1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SNCA","MeSH1":"lewy body disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SNCA","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SNCA","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SNRNP70","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SOAT1","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOAT1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOAT1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOAT1","MeSH1":"dermatitis, seborrheic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOAT1","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"SOAT1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOAT1","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOAT1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOCS1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SOCS1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOCS1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SOCS2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOCS3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOCS5","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOCS6","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOCS7","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"bronchopulmonary dysplasia","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"hepatolenticular degeneration","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"penile induration","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"radiodermatitis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SOD1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"esophagitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD2","MeSH1":"xerostomia","MeSH2":"Stomatognathic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD3","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD3","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD3","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SOD3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOD3","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SORD","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SOST","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SOST","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SOST","MeSH1":"hypophosphatasia","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SOST","MeSH1":"osteogenesis imperfecta","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SOST","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SPG7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SPHK1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SPHK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SPHK1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPHK2","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SPHK2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SPHK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SPHK2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPINK1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SPINK1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SPINK1","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPINK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SPINK5","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPINK5","MeSH1":"netherton syndrome","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPINT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPINT2","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPINT2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPINT2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPON1","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPP1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SPP1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPP1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPP1","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SPP1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPP1","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SPR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SQLE","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SQLE","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SQLE","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"ear diseases","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"fibrosarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SRC","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SRC","MeSH1":"liposarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRC","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"duodenal ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"dysuria","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"hirsutism","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"hypogonadism","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"stomach ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SRD5A1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A2","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SRD5A2","MeSH1":"hypogonadism","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRD5A2","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SRD5A2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SREBF2","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SREBF2","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SREBF2","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SRR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRR","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SRR","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"malignant carcinoid syndrome","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SSTR1","MeSH1":"pituitary neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"malignant carcinoid syndrome","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SSTR2","MeSH1":"pituitary neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR2","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"malignant carcinoid syndrome","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SSTR3","MeSH1":"pituitary neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR4","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"acromegaly","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"carcinoma, merkel cell","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"malignant carcinoid syndrome","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"pituitary acth hypersecretion","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SSTR5","MeSH1":"pituitary neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SSTR5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ST13","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ST13","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ST14","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ST14","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ST14","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAB1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"STAB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"STAT1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"eye diseases","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"STAT3","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"STAT4","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT6","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT6","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STAT6","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STEAP1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STEAP3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STK4","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STK4","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STMN1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STMN1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STMN1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STMN1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"STS","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"STS","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STS","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STS","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"STS","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STS","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"STS","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SULT1E1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SULT1E1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SUMF1","MeSH1":"mucopolysaccharidosis iii","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"bipolar disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"epilepsies, partial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SV2A","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SV2A","MeSH1":"epilepsy, tonic-clonic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"SV2A","MeSH1":"essential tremor","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SV2A","MeSH1":"unverricht-lundborg syndrome","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"celiac disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"uveitis","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"SYK","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"SYVN1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TAAR1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TAAR1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"burkholderia infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"diarrhea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"dyspepsia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"fever","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TACR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"phobic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"postoperative nausea and vomiting","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TACR1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"sleep disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"sleep initiation and maintenance disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"stress disorders, post-traumatic","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"tinnitus","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"colic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"depressive disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"alcoholism","MeSH2":"Substance-Related Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"endometriosis","MeSH2":"Female Urogenital Diseases and Pregnancy Complications","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"nausea","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"schizophrenia","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TACR3","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACSTD2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACSTD2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACSTD2","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TACSTD2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACSTD2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TACSTD2","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TARDBP","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TARDBP","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"myositis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBK1","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"bursitis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"hepatorenal syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"rhinitis, allergic, perennial","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXA2R","MeSH1":"venous insufficiency","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"cerebral infarction","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"colitis","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"mastodynia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"proteinuria","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"urinary calculi","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"vasospasm, intracranial","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TBXAS1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TCF4","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TCF4","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TCIRG1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TCIRG1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TCIRG1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TCIRG1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TCIRG1","MeSH1":"periodontitis","MeSH2":"Stomatognathic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TCN2","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TCN2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TDGF1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TDP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TEK","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TEK","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TEK","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TEK","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TENM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERF1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"anemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TERT","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFF1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TFF1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TFF1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TFF1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TFF3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TFF3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TFF3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TFF3","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"angioedema","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"angioedemas, hereditary","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TFPI","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"hemophilia b","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"hemorrhage","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"pneumococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"pneumonia","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"retinal vein occlusion","MeSH2":"Eye Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TFPI","MeSH1":"von willebrand diseases","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TFRC","MeSH1":"urogenital neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFA","MeSH1":"bronchiolitis obliterans","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFA","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFA","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFA","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"burns","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"endomyocardial fibrosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"sensation disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB3","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB3","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFB3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFB3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"liver diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFBR1","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFBR2","MeSH1":"cataract","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR2","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR2","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TGFBR2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGFBR2","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR2","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR2","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGFBR3","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TGM2","MeSH1":"celiac disease","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGM2","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGM2","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGM2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TGM2","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGM2","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TGM2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TH","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TH","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"blood coagulation disorders","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"disseminated intravascular coagulation","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"intracranial thrombosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THBD","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THBS1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THPO","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THPO","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THPO","MeSH1":"thrombocytosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THPO","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THRA","MeSH1":"arrhythmias, cardiac","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"hyperlipidemias","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"hypertriglyceridemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"metabolic syndrome x","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"THRB","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TIE1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TIE1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TIMP1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TIMP2","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TIMP2","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TIMP2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TIMP3","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TIMP4","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TKT","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR2","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR2","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR2","MeSH1":"leishmaniasis","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR2","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR2","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR2","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TLR2","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"fatigue syndrome, chronic","MeSH2":"Virus Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"TLR3","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR3","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"leishmaniasis","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TLR4","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"burkholderia infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"pseudomonas infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR5","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR6","MeSH1":"anemia, aplastic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR6","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR6","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TLR6","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"barrett esophagus","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"coronavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"streptococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR7","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"herpes simplex","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR8","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"food hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"TLR9","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"malaria","MeSH2":"Parasitic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"myasthenia gravis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TLR9","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMEFF2","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TMPRSS15","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TMPRSS15","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TMPRSS6","MeSH1":"anemia, sickle cell","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TMPRSS6","MeSH1":"hemochromatosis","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMPRSS6","MeSH1":"thalassemia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"bronchiectasis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"bronchitis, chronic","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"corneal ulcer","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"emphysema","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"epidermolysis bullosa","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"motor neuron disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"postthrombotic syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TMSB4X","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNC","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFAIP6","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFAIP8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF10A","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10A","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10A","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10A","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10A","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF10B","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF11A","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF11A","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF11B","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF12A","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF13C","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF13C","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF13C","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF13C","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF18","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF18","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"arthritis, psoriatic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"behcet syndrome","MeSH2":"Stomatognathic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"carcinoma, neuroendocrine","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"cardiomyopathy, hypertrophic","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"cerebral hemorrhage","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"fibrosis","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"gliosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"hepatitis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"ileus","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"leiomyoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"liver cirrhosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"mucositis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"noonan syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"pulmonary edema","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"reperfusion injury","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"retinal diseases","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"spondylitis, ankylosing","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF1A","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF21","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF4","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF4","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF4","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF4","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF4","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF8","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNFRSF8","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF8","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF8","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNFRSF8","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNFRSF8","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNFRSF8","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF9","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF9","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF9","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFRSF9","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF9","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF9","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFRSF9","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFRSF9","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF10","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFSF10","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF10","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFSF10","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF10","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF10","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF10","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF10","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"bone diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"bone diseases, metabolic","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"hypercalcemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNFSF11","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFSF13","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"glomerulonephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"iga deficiency","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"igg deficiency","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"lupus nephritis","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"purpura, thrombocytopenic, idiopathic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"sjogren's syndrome","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"vasculitis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF13B","MeSH1":"wegener granulomatosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFSF14","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF14","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF15","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF15","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF15","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF4","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF4","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF4","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TNFSF4","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TNFSF8","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNFSF8","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNKS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNKS2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNNC1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TNNC1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TNPO1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TNPO1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"anus neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"nasopharyngeal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"neuroectodermal tumors, primitive","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"thymoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"tissue adhesions","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP1","MeSH1":"vaginal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"bacterial infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"bone neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"eye neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"hodgkin disease","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"multiple sclerosis, chronic progressive","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"multiple sclerosis, relapsing-remitting","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"mycoses","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"neuroblastoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"peptic ulcer","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"respiratory tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"testicular neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2A","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TOP2A","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TOP2B","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2B","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOP2B","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOR1A","MeSH1":"dystonia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TOR1A","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"hearing loss","MeSH2":"Otorhinolaryngologic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"leukoplakia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"li-fraumeni syndrome","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"mouth neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"skin neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"vitiligo","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TP53","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TPBG","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"malignant carcinoid syndrome","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPH1","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TPP1","MeSH1":"neuronal ceroid-lipofuscinoses","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TPP2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"candidiasis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"conjunctivitis, allergic","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"coronary thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"gastrointestinal diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"rhinitis, allergic, perennial","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"skin diseases, infectious","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TPSAB1","MeSH1":"staphylococcal infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"barrett esophagus","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRAF6","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TREM1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TREM1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TREM1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TREM1","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TREM1","MeSH1":"shock, traumatic","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TREM2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TREM2","MeSH1":"metabolic diseases","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TREM2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"amnesia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"dementia, vascular","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"dyskinesias","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"memory disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRHR","MeSH1":"spinocerebellar ataxias","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TRIM37","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRIM63","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"respiratory tract diseases","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPA1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPC5","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPC5","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPM7","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPM7","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPM7","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPM7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPM7","MeSH1":"retinal artery occlusion","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"leiomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPM8","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"cluster headache","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"cough","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"crohn disease","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TRPV1","MeSH1":"eczema","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TRPV1","MeSH1":"gastroesophageal reflux","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"migraine disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TRPV1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TRPV1","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TRPV1","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TRPV1","MeSH1":"neuroma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TRPV1","MeSH1":"pain, postoperative","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"pruritus","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"rhinitis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"rhinitis, allergic, seasonal","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"spasm","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"tendinopathy","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"urinary incontinence","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV1","MeSH1":"xerophthalmia","MeSH2":"Eye Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV3","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV3","MeSH1":"musculoskeletal pain","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV3","MeSH1":"neuralgia","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV3","MeSH1":"neuralgia, postherpetic","MeSH2":"Nervous System Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV3","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TRPV3","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV3","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPV4","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV4","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV4","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV4","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TRPV4","MeSH1":"pulmonary edema","MeSH2":"Respiratory Tract Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV6","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV6","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TRPV6","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TRPV6","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TSG101","MeSH1":"hemorrhagic fever, ebola","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSG101","MeSH1":"hepatitis b","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSG101","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSG101","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSG101","MeSH1":"influenza, human","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSHR","MeSH1":"goiter","MeSH2":"Endocrine System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSHR","MeSH1":"hyperthyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSHR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TSHR","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TSLP","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TSLP","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"anxiety","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"anxiety disorders","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"depression","MeSH2":"Behavior and Behavior Mechanisms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"epilepsy","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"irritable bowel syndrome","MeSH2":"Digestive System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"panic disorder","MeSH2":"Mental Disorders","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TSPO","MeSH1":"psychotic disorders","MeSH2":"Mental Disorders","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TTK","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TTR","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TTR","MeSH1":"amyloidosis","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Registered","approved":true}
{"entrez_gene_symbol":"TTR","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TTR","MeSH1":"diabetic cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TUB","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TUBB3","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TULP1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TULP2","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TUSC2","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TXN","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"autoimmune diseases","MeSH2":"Immune System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYK2","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"TYMP","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Pre-registration","approved":false}
{"entrez_gene_symbol":"TYMP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"arthritis, juvenile rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"hepatitis c","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"keratosis, actinic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"lymphoma, t-cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"neuroectodermal tumors, primitive","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"osteoarthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"osteosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"Withdrawn","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"sarcoma, ewing","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYMS","MeSH1":"urethral neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"TYMS","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYR","MeSH1":"hiv infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYR","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"TYR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYR","MeSH1":"papillomavirus infections","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYR","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"TYRO3","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"TYRP1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"TYRP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UBA1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UBA6","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"UBE3A","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"UCHL5","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UCN3","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UCP2","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UCP2","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UCP2","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UCP2","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UGCG","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UGCG","MeSH1":"fabry disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UGCG","MeSH1":"gaucher disease","MeSH2":"Nervous System Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"UGCG","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"UGCG","MeSH1":"sandhoff disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UGCG","MeSH1":"tay-sachs disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UHRF1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UMPS","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"UPK1A","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UPK1B","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UPK2","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"UPP1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UPP1","MeSH1":"virus diseases","MeSH2":"Virus Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP14","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"USP14","MeSH1":"cystic fibrosis","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP14","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP14","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP14","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"USP14","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"USP19","MeSH1":"cachexia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"USP21","MeSH1":"alzheimer disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP21","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP33","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP34","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"USP47","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"USP7","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP7","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"USP7","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"USP8","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UTRN","MeSH1":"cardiomyopathy, dilated","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"UTRN","MeSH1":"muscular dystrophies","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"UTRN","MeSH1":"muscular dystrophies, limb-girdle","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"UTRN","MeSH1":"muscular dystrophy, duchenne","MeSH2":"Musculoskeletal Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UTS2R","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"UTS2R","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UTS2R","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UTS2R","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"UTS2R","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UTS2R","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UTS2R","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UTS2R","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"UVRAG","MeSH1":"wounds and injuries","MeSH2":"Wounds and Injuries","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VASH1","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VAT1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VCAM1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VDAC2","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDAC2","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDAC3","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDAC3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"acne vulgaris","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VDR","MeSH1":"alopecia","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"colitis, ulcerative","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"dermatitis, atopic","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"dermatitis, contact","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"diabetes mellitus, type 1","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"hyperparathyroidism","MeSH2":"Endocrine System Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VDR","MeSH1":"hyperphosphatemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"ichthyosis","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VDR","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"immunologic deficiency syndromes","MeSH2":"Immune System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"infertility, male","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"inflammatory bowel diseases","MeSH2":"Digestive System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"keratosis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VDR","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"lupus erythematosus, cutaneous","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"menstruation disturbances","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"musculoskeletal diseases","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VDR","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"prostatic diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"proteinuria","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VDR","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"renal osteodystrophy","MeSH2":"Musculoskeletal Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VDR","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"tissue adhesions","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"urinary bladder, overactive","MeSH2":"Male Urogenital Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"urinary tract infections","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VDR","MeSH1":"vitamin d deficiency","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"abnormalities, multiple","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"adrenal gland neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"amyotrophic lateral sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"ascites","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"atherosclerosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"carcinoid tumor","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"cardiomyopathies","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"coronary restenosis","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"dementia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"diabetes complications","MeSH2":"Endocrine System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"diabetic nephropathies","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"diabetic neuropathies","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"diabetic retinopathy","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"leukemia, mast-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"macular edema","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"mastocytosis","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"myocardial infarction","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"myopia","MeSH2":"Eye Diseases","drug_phase":"Pre-registration","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"neurofibromatoses","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"parkinson disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"peripheral vascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Registered","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"polycystic kidney diseases","MeSH2":"Male Urogenital Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"psoriasis","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"renal insufficiency","MeSH2":"Male Urogenital Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"retinal vein occlusion","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFA","MeSH1":"rhabdomyosarcoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"rosacea","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"sarcoma, kaposi","MeSH2":"Virus Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"scleroderma, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"skin diseases","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"soft tissue neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"spinal cord injuries","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"thromboangiitis obliterans","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"thyroid neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"ulcer","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"urinary bladder neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFA","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VEGFB","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFB","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFB","MeSH1":"diabetes mellitus, type 2","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFB","MeSH1":"ischemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFB","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFB","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFB","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"lymphedema","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VEGFC","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VHL","MeSH1":"von hippel-lindau disease","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIM","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VIMP","MeSH1":"obesity","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIP","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIP","MeSH1":"infection","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIP","MeSH1":"sepsis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"acute lung injury","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"erectile dysfunction","MeSH2":"Male Urogenital Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VIPR1","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"hypertension, pulmonary","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"radiation injuries","MeSH2":"Wounds and Injuries","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"respiratory distress syndrome, adult","MeSH2":"Respiratory Tract Diseases","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"sarcoidosis","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"sexual dysfunction, physiological","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR1","MeSH1":"thrombocytopenia","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR2","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VIPR2","MeSH1":"hypertension","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VIPR2","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VIPR2","MeSH1":"pulmonary disease, chronic obstructive","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VKORC1","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VKORC1","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VKORC1","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"VLDLR","MeSH1":"hypercholesterolemia","MeSH2":"Nutritional and Metabolic Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VSIG1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VTCN1","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"VTCN1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VTCN1","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VTCN1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VWF","MeSH1":"acute coronary syndrome","MeSH2":"Cardiovascular Diseases","drug_phase":"Suspended","approved":false}
{"entrez_gene_symbol":"VWF","MeSH1":"brain ischemia","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VWF","MeSH1":"craniocerebral trauma","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"VWF","MeSH1":"hemophilia a","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"VWF","MeSH1":"purpura, thrombotic thrombocytopenic","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VWF","MeSH1":"thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VWF","MeSH1":"venous thrombosis","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"VWF","MeSH1":"von willebrand diseases","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"WAS","MeSH1":"wiskott-aldrich syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"anus neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"endometrial neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"esophageal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"sarcoma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WEE1","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"WFDC1","MeSH1":"prostatic hyperplasia","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"WFDC1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"WRN","MeSH1":"werner syndrome","MeSH2":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"gastrointestinal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"hematologic neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"leukemia","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"lung neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"mesothelioma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"small cell lung carcinoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"WT1","MeSH1":"stomach neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XAF1","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XAF1","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XAF1","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XAF1","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XCL1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XDH","MeSH1":"angina pectoris","MeSH2":"Cardiovascular Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XDH","MeSH1":"arthritis, gouty","MeSH2":"Musculoskeletal Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"XDH","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XDH","MeSH1":"cardiovascular diseases","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"XDH","MeSH1":"fatty liver","MeSH2":"Digestive System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XDH","MeSH1":"heart failure","MeSH2":"Cardiovascular Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"XDH","MeSH1":"hyperuricemia","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"XDH","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XDH","MeSH1":"urogenital abnormalities","MeSH2":"Male Urogenital Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"biliary tract neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"colorectal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"fallopian tube neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"glaucoma","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"huntington disease","MeSH2":"Nervous System Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"kidney neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"liver neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"lymphoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"lymphoma, b-cell","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"neoplasms, basal cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"neoplasms, squamous cell","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"nervous system diseases","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"ocular motility disorders","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"pain","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"peritoneal neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase III Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XIAP","MeSH1":"uterine cervical neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XPA","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"XPO1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"XPO1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"XPO1","MeSH1":"lymphoma, non-hodgkin","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"XPO1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"XPO1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"XPO1","MeSH1":"tuberculosis","MeSH2":"Bacterial Infections and Mycoses","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"XPO1","MeSH1":"waldenstrom macroglobulinemia","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"YBX1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"brain neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"breast neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"carcinoma, non-small-cell lung","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"head and neck neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"hypereosinophilic syndrome","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"leukemia, lymphoid","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"YES1","MeSH1":"leukemia, myeloid, acute","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"leukemia, myelomonocytic, chronic","MeSH2":"Neoplasms","drug_phase":"Launched","approved":true}
{"entrez_gene_symbol":"YES1","MeSH1":"macular degeneration","MeSH2":"Eye Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"melanoma","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"multiple myeloma","MeSH2":"Neoplasms","drug_phase":"Phase I Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"myelodysplastic syndromes","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"pancreatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"polycythemia vera","MeSH2":"Hemic and Lymphatic Diseases","drug_phase":"Phase II Clinical Trial","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"prostatic neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"YES1","MeSH1":"wet macular degeneration","MeSH2":"Eye Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"YME1L1","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"YWHAG","MeSH1":"idiopathic pulmonary fibrosis","MeSH2":"Respiratory Tract Diseases","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"YWHAH","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"arthritis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"arthritis, rheumatoid","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"asthma","MeSH2":"Respiratory Tract Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"hypersensitivity","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"immune system diseases","MeSH2":"Immune System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"inflammation","MeSH2":"Pathological Conditions, Signs and Symptoms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"lupus erythematosus, systemic","MeSH2":"Skin and Connective Tissue Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"multiple sclerosis","MeSH2":"Nervous System Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZAP70","MeSH1":"osteoporosis","MeSH2":"Musculoskeletal Diseases","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZBTB17","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"No Development Reported","approved":false}
{"entrez_gene_symbol":"ZP3","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Discontinued","approved":false}
{"entrez_gene_symbol":"ZP3","MeSH1":"ovarian neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}
{"entrez_gene_symbol":"ZYX","MeSH1":"neoplasms","MeSH2":"Neoplasms","drug_phase":"Preclinical","approved":false}