Package: TwoSampleMR
Title: Two Sample MR Functions and Interface to MRC Integrative
        Epidemiology Unit OpenGWAS Database
Version: 0.7.9
Authors@R: c(
    person("Gibran", "Hemani", , "g.hemani@bristol.ac.uk", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0003-0920-1055")),
    person("Philip", "Haycock", , "philip.haycock@bristol.ac.uk", role = "aut",
           comment = c(ORCID = "0000-0001-5001-3350")),
    person("Jie", "Zheng", , "Jie.Zheng@bristol.ac.uk", role = "aut",
           comment = c(ORCID = "0000-0002-6623-6839")),
    person("Tom", "Gaunt", , "Tom.Gaunt@bristol.ac.uk", role = "aut",
           comment = c(ORCID = "0000-0003-0924-3247")),
    person("Ben", "Elsworth", , "Ben.Elsworth@bristol.ac.uk", role = "aut",
           comment = c(ORCID = "0000-0001-7328-4233")),
    person("Tom", "Palmer", , "remlapmot@hotmail.com", role = "aut",
           comment = c(ORCID = "0000-0003-4655-4511")),
    person("Marina", "Vabistsevits", role = "ctb",
           comment = c(ORCID = "0000-0003-1121-6790"))
  )
Description: A package for performing Mendelian randomization using
        GWAS summary data. It uses the IEU OpenGWAS database
        <https://opengwas.io> to automatically obtain data, and a wide
        range of methods to run the analysis.
License: MIT + file LICENSE
URL: https://github.com/MRCIEU/TwoSampleMR,
        https://mrcieu.github.io/TwoSampleMR/
BugReports: https://github.com/MRCIEU/TwoSampleMR/issues/
Depends: R (>= 4.1.0)
Imports: cli, cowplot, data.table, dplyr, ggplot2 (>= 3.4.0), glmnet,
        gridExtra, gtable, ieugwasr (>= 1.1.0), jsonlite, knitr,
        lattice, magrittr, MASS, MRMix, MRPRESSO, pbapply, psych,
        RadialMR, rmarkdown, tidyr
Suggests: Cairo, car, markdown, MendelianRandomization, meta, mr.raps,
        MRInstruments, randomForest, testthat
VignetteBuilder: knitr
Remotes: gqi/MRMix, mrcieu/MRInstruments, MRPRESSO=rondolab/MR-PRESSO,
        qingyuanzhao/mr.raps, WSpiller/RadialMR
Config/roxygen2/markdown: TRUE
Config/roxygen2/version: 8.0.0
Encoding: UTF-8
Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libssl-dev
Repository: https://mrcieu.r-universe.dev
Date/Publication: 2026-06-24 09:35:06 UTC
RemoteUrl: https://github.com/MRCIEU/TwoSampleMR
RemoteRef: HEAD
RemoteSha: 3d119f20d6fc164b0c7f710f5590fee9580f2c7b
NeedsCompilation: no
Packaged: 2026-06-24 10:27:38 UTC; root
Author: Gibran Hemani [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-0920-1055>),
  Philip Haycock [aut] (ORCID: <https://orcid.org/0000-0001-5001-3350>),
  Jie Zheng [aut] (ORCID: <https://orcid.org/0000-0002-6623-6839>),
  Tom Gaunt [aut] (ORCID: <https://orcid.org/0000-0003-0924-3247>),
  Ben Elsworth [aut] (ORCID: <https://orcid.org/0000-0001-7328-4233>),
  Tom Palmer [aut] (ORCID: <https://orcid.org/0000-0003-4655-4511>),
  Marina Vabistsevits [ctb] (ORCID:
    <https://orcid.org/0000-0003-1121-6790>)
Maintainer: Gibran Hemani <g.hemani@bristol.ac.uk>