{ "_id": "6abe336f99f7aa8c6aa53a02", "Type": "Package", "Package": "ColliderBias", "Title": "Adjust collider bias and weak instrument bias in Mendelian\nRandomisation", "Version": "1.0.1", "Author": "Frank Dudbridge, Siyang Cai", "Maintainer": "Frank Dudbridge , Siyang\nCai ", "Description": "This package provides adjustment for collider bias and\nweak instrument bias in association statistics in the context\nof a genome-wide association study for a subsequent event,\nusing CWLS (Corrected Weighted Least Squares), MR-RAPS and\nSlope Hunter. An estimation of true causal effect between\ndisease progression and an exposure of interest can be computed\nusing generalised instrument effect regression with CWBLS\n(Corrected Weighted Bivariate Least Squares).", "License": "GPL-3", "URL": "https://github.com/SiyangCai/ColliderBias", "BugReports": "https://github.com/SiyangCai/ColliderBias/issues/", "Remotes": [ "Osmahmoud/SlopeHunter" ], "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.3.2", "Config/pak/sysreqs": "cmake make libicu-dev libuv1-dev libssl-dev", "Repository": "https://mrcieu.r-universe.dev", "Date/Publication": "2024-11-01 14:28:04 UTC", "RemoteUrl": "https://github.com/SiyangCai/ColliderBias", "RemoteRef": "HEAD", "RemoteSha": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "NeedsCompilation": "no", "Packaged": { "Date": "2026-10-01 10:14:34 UTC", "User": "root" }, "_user": "mrcieu", "_type": "src", "_file": "ColliderBias_1.0.1.tar.gz", "_fileid": "https://r2.ropensci.org/f353b629a7f5e3e820f5d643db03fc9d3056fd76fa4f7a5bdb544ad794642e77", "_filesize": 333228, "_sha256": "f353b629a7f5e3e820f5d643db03fc9d3056fd76fa4f7a5bdb544ad794642e77", "_expires": "2027-01-09T10:18:21.000Z", "_created": "2026-10-01T10:14:34.000Z", "_published": "2026-10-01T10:18:23.484Z", "_jobs": [ { "job": 110322424265, "time": 192, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "11154755894" }, { "job": 110322424604, "time": 162, "config": "linux-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "11154447119" }, { "job": 110322424351, "time": 117, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "11154351656" }, { "job": 110322424331, "time": 83, "config": "macos-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "11153664830" }, { "job": 110321109814, "time": 223, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "11154670925" }, { "job": 110322424195, "time": 133, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "11154247787" }, { "job": 110322424257, "time": 64, "config": "windows-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "11153649745" }, { "job": 110322424367, "time": 67, "config": "windows-oldrel-x86_64", "r": "4.5.3", "check": "OK", "artifact": "11153699524" }, { "job": 110322424286, "time": 79, "config": "windows-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "11154755549" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236", "_status": "success", "_upstream": "https://github.com/SiyangCai/ColliderBias", "_commit": { "id": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "author": "Siyang Cai <84019623+SiyangCai@users.noreply.github.com>", "committer": "GitHub ", "message": "Update README.md", "time": 1730471284 }, "_maintainer": { "name": "Frank Dudbridge", "email": "sc814@leicester.ac.uk", "login": "fdudbridge", "description": "", "uuid": 26600572 }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 3.5", "role": "Depends" }, { "package": "boot", "role": "Imports" }, { "package": "mr.raps", "role": "Imports" }, { "package": "SlopeHunter", "role": "Imports" } ], "_owner": "siyangcai", "_selfowned": false, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 2, "_contributors": [ { "user": "remlapmot", "count": 21, "uuid": 3777473 }, { "user": "siyangcai", "count": 21, "uuid": 84019623 } ], "_userbio": { "uuid": 15654827, "type": "organization", "name": "MRC Integrative Epidemiology Unit", "followers": 257 }, "_downloads": { "count": 0, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/ColliderBias" }, "_devurl": "https://github.com/siyangcai/colliderbias", "_searchresults": 1, "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/ColliderBias.html", "extra/contents.json", "extra/manual.pdf", "extra/readme.html", "extra/readme.md" ], "_cranurl": false, "_exports": [ "CWBLS", "methodCB" ], "_datasets": [ { "name": "testData", "title": "Sample simulated genome-wide association study (GWAS) summary statisitcs for analysis.", "object": "testData", "class": [ "data.frame" ], "fields": [ "xbeta", "xse", "dbeta", "dse", "ybeta", "yse" ], "rows": 10000, "table": true, "tojson": true } ], "_help": [ { "page": "CWBLS", "title": "Estimate true causal effect in bivariate Mendelian randomization to adjust for collider bias and weak instrument bias.", "topics": [ "CWBLS" ] }, { "page": "methodCB", "title": "Adjust association statistics for collider bias and weak instrument bias in Mendelian randomization.", "topics": [ "methodCB" ] }, { "page": "testData", "title": "Sample simulated genome-wide association study (GWAS) summary statisitcs for analysis.", "topics": [ "testData" ] } ], "_readme": "https://github.com/SiyangCai/ColliderBias/raw/HEAD/README.md", "_rundeps": [ "askpass", "base64enc", "boot", "bslib", "cachem", "cli", "cpp11", "crosstalk", "crul", "curl", "data.table", "digest", "dplyr", "evaluate", "farver", "fastmap", "fontawesome", "fs", "generics", "ggplot2", "ggrepel", "glue", "gridExtra", "gtable", "highr", "htmltools", "htmlwidgets", "httpcode", "httr", "ieugwasr", "isoband", "jquerylib", "jsonlite", "knitr", "labeling", "later", "lazyeval", "lifecycle", "magrittr", "mclust", "memoise", "mime", "mr.raps", "nortest", "openssl", "otel", "pillar", "pkgconfig", "plotly", "plyr", "promises", "purrr", "R6", "rappdirs", "RColorBrewer", "Rcpp", "rlang", "rmarkdown", "rootSolve", "rsnps", "S7", "sass", "scales", "SlopeHunter", "stringi", "stringr", "sys", "tibble", "tidyr", "tidyselect", "tinytex", "triebeard", "urltools", "utf8", "vctrs", "viridisLite", "withr", "xfun", "yaml" ], "_score": 2, "_indexed": false, "_nocasepkg": "colliderbias", "_universes": [ "mrcieu" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "1.0.1", "date": "2026-10-01T10:17:54.000Z", "distro": "resolute", "commit": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "fileid": "https://r2.ropensci.org/007c4e7ecad4d2ab3bbc39967f0ecbdd79957aa9f8daefead4e600e27b28aebf", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236" }, { "r": "4.6.1", "os": "linux", "version": "1.0.1", "date": "2026-10-01T10:17:24.000Z", "distro": "resolute", "commit": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "fileid": "https://r2.ropensci.org/2d84d702267a5cf6a43081913d8cdc2c825279413d8364767a9eccff9f7a362c", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236" }, { "r": "4.5.3", "os": "mac", "version": "1.0.1", "date": "2026-10-01T10:16:44.000Z", "commit": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "fileid": "https://r2.ropensci.org/978daa2f3b71d0df7df76c091506cd63eb5a9772d1746eb4438cc073eceb8eea", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236" }, { "r": "4.6.1", "os": "mac", "version": "1.0.1", "date": "2026-10-01T10:16:12.000Z", "commit": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "fileid": "https://r2.ropensci.org/c88f98eb77ea6971fc0d6deefd0f4c82f591fb00e1955fe1b7c28365963948b5", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236" }, { "r": "4.6.0", "os": "wasm", "version": "1.0.1", "date": "2026-10-01T10:17:06.000Z", "commit": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "fileid": "https://r2.ropensci.org/5857e0926fb52a2e837647c6812fd1d20e690eee02d70be48f07b39582cb403a", "status": "success", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236" }, { "r": "4.7.0", "os": "win", "version": "1.0.1", "date": "2026-10-01T10:15:45.000Z", "commit": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "fileid": "https://r2.ropensci.org/443bd2e691d399334f3f88ec7542f7dd2f3e0d824d2dc9cf20f7da91c0c39052", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236" }, { "r": "4.5.3", "os": "win", "version": "1.0.1", "date": "2026-10-01T10:15:47.000Z", "commit": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "fileid": "https://r2.ropensci.org/6697db7381f0f49fea6cee23b2a3d4f87c1a7ca3f7248ad6200cf0f12fbdb07e", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236" }, { "r": "4.6.1", "os": "win", "version": "1.0.1", "date": "2026-10-01T10:15:58.000Z", "commit": "66606d074c5cfd5263a0e2234ceb0a88fc9fdbc1", "fileid": "https://r2.ropensci.org/8eaa537fe8e3268e596847b56e34e3d29d3c5b89949b77bc66500eb146552a9e", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/36847483236" } ] }