{
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  "Package": "MRCorge",
  "Title": "Mendelian Randomization based on the core gene hypothesis for\npolygenic exposures",
  "Version": "0.1.0",
  "Authors@R": "c(person(given = \"Wenmin\",\nfamily = \"Zhang\",\nrole = c(\"aut\", \"cre\"),\nemail = \"wenmin.zhang@mail.mcgill.ca\"),\nperson(given = \"Tianyuan\",\nfamily = \"Lu\",\nrole = c(\"aut\"),\nemail = \"tianyuan.lu@wisc.edu\"))",
  "Description": "This package performs Mendelian Randomization (MR)\nanalyses based on the core gene hypothesis for polygenic\nexposures. MR CORGE identifies a small number of putative core\ninstruments that are more likely to affect genes with a direct\nbiological role in an exposure and obtains causal effect\nestimates based on these instruments, thereby reducing the risk\nof horizontal pleiotropy.",
  "License": "CC-BY-NC-ND 4.0",
  "URL": "https://github.com/zhwm/MRCORGE, https://zhwm.github.io/MRCorge/",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "RoxygenNote": "7.3.1",
  "VignetteBuilder": "knitr",
  "Remotes": [
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  "Config/pak/sysreqs": "cmake make libicu-dev libuv1-dev libssl-dev",
  "Repository": "https://mrcieu.r-universe.dev",
  "Date/Publication": "2024-10-19 19:11:47 UTC",
  "RemoteUrl": "https://github.com/zhwm/MRCorge",
  "RemoteRef": "HEAD",
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  "Packaged": {
    "Date": "2026-05-15 16:21:36 UTC",
    "User": "root"
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  "Author": "Wenmin Zhang [aut, cre],\nTianyuan Lu [aut]",
  "Maintainer": "Wenmin Zhang <wenmin.zhang@mail.mcgill.ca>",
  "MD5sum": "95e8a954ff309effa364063b3774cb5e",
  "_user": "mrcieu",
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