{ "_id": "6a226cc9cd65a98ecbd471da", "Package": "MRchecks", "Title": "Tools for detecting genetic variants whose effect changes with\nage and associated bias", "Version": "0.0.0.9000", "Authors@R": "person(given = \"Jeremy\",\nfamily = \"Labrecque\",\nrole = c(\"aut\", \"cre\"),\nemail = \"j.labrecque@erasmusmc.nl\",\ncomment = c(ORCID = \"0000-0002-1028-2158\"))", "Description": "This package is a collection of tools to detect SNPs whose\neffect varies with age whose. owoeosds sd sd. sdsfw. sdfsers s\nes .", "License": "`use_mit_license()`, `use_gpl3_license()` or friends to pick a\nlicense", "Encoding": "UTF-8", "LazyData": "true", "Roxygen": "list(markdown = TRUE)", "RoxygenNote": "7.1.1", "Config/pak/sysreqs": "cmake make libicu-dev", "Repository": "https://mrcieu.r-universe.dev", "Date/Publication": "2021-09-15 19:53:17 UTC", "RemoteUrl": "https://github.com/jalabrecque/MRchecks", "RemoteRef": "HEAD", "RemoteSha": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-05 06:26:58 UTC", "User": "root" }, "Author": "Jeremy Labrecque [aut, cre] (ORCID:\n)", "Maintainer": "Jeremy Labrecque ", "MD5sum": "2be0c512274d2e101cf7bd097e8ce0da", "_user": "mrcieu", "_type": "src", "_file": "MRchecks_0.0.0.9000.tar.gz", "_fileid": "d5242b81435f9f96fad0909398b28591f96048e79b545c720e1a69b1ef7f8b04", "_filesize": 726543, "_sha256": "d5242b81435f9f96fad0909398b28591f96048e79b545c720e1a69b1ef7f8b04", "_created": "2026-06-05T06:26:58.000Z", "_published": "2026-06-05T06:29:29.578Z", "_distro": "noble", "_jobs": [ { "job": 79675837083, "time": 123, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "WARNING", "artifact": "7430241462" }, { "job": 79675837092, "time": 125, "config": "linux-release-x86_64", "r": "4.6.0", "check": "WARNING", "artifact": "7430241658" }, { "job": 79675837093, "time": 111, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "WARNING", "artifact": "7430238685" }, { "job": 79675837094, "time": 121, "config": "macos-release-arm64", "r": "4.6.0", "check": "WARNING", "artifact": "7430240804" }, { "job": 79675530939, "time": 162, "config": "source", "r": "4.6.0", "check": "OK", "artifact": "7430213526" }, { "job": 79675837065, "time": 112, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "7430239047" }, { "job": 79675837104, "time": 74, "config": "windows-devel", "r": "4.7.0", "check": "WARNING", "artifact": "7430230531" }, { "job": 79675837127, "time": 63, "config": "windows-oldrel", "r": "4.5.3", "check": "WARNING", "artifact": "7430227870" }, { "job": 79675837091, "time": 80, "config": "windows-release", "r": "4.6.0", "check": "WARNING", "artifact": "7430231918" } ], "_buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/jalabrecque/MRchecks", "_commit": { "id": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "author": "Jeremy Labrecque ", "committer": "GitHub ", "message": "Update README.md", "time": 1631735597 }, "_maintainer": { "name": "Jeremy Labrecque", "email": "j.labrecque@erasmusmc.nl", "login": "jalabrecque", "description": "Causal inference in epidemiologic studies. More specifically my current interests are in genetic epi, social epi and everything in between.", "uuid": 10617433, "orcid": "0000-0002-1028-2158" }, "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 2.10", "role": "Depends" }, { "package": "mgcv", "role": "Imports" }, { "package": "magrittr", "role": "Imports" }, { "package": "dplyr", "role": "Imports" }, { "package": "itsadug", "role": "Imports" }, { "package": "AER", "role": "Imports" }, { "package": "plotfunctions", "role": "Imports" } ], "_owner": "jalabrecque", "_selfowned": false, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 2, "_contributors": [ { "user": "jalabrecque", "count": 35, "uuid": 10617433 } ], "_userbio": { "uuid": 15654827, "type": "organization", "name": "MRC Integrative Epidemiology Unit" }, "_downloads": { "count": 0, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/MRchecks" }, "_devurl": "https://github.com/jalabrecque/mrchecks", "_searchresults": 0, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/MRchecks.html", "extra/readme.html", "extra/readme.md", "manual.pdf" ], "_cranurl": false, "_exports": [ "%>%", "SNPxAGE_bias", "SNPxAGE_effect", "SNPxAGE_model", "SNPxAGE_plot" ], "_datasets": [ { "name": "test_data", "title": "", "object": "test_data", "class": [ "data.frame" ], "fields": [ "age", "SNP", "y", "c" ], "rows": 10000, "table": true, "tojson": true } ], "_help": [ { "page": "SNPxAGE_bias", "title": "Estimate bias from age-varying genetic effects in Mendelian randomization", "topics": [ "SNPxAGE_bias" ] }, { "page": "SNPxAGE_effect", "title": "Function to estimate the per-allele effect at each age", "topics": [ "SNPxAGE_effect" ] }, { "page": "SNPxAGE_model", "title": "Flexibly modeling the age/phenotype association by genetic variant", "topics": [ "SNPxAGE_model" ] }, { "page": "SNPxAGE_plot", "title": "Function to plot absolute value of pheontype for each genotype", "topics": [ "SNPxAGE_plot" ] } ], "_readme": "https://github.com/jalabrecque/MRchecks/raw/HEAD/README.md", "_rundeps": [ "abind", "AER", "backports", "boot", "broom", "car", "carData", "cli", "colorspace", "cowplot", "cpp11", "Deriv", "doBy", "dplyr", "farver", "forecast", "Formula", "fracdiff", "generics", "ggplot2", "glue", "gtable", "isoband", "itsadug", "labeling", "lattice", "lifecycle", "lme4", "lmtest", "magrittr", "MASS", "Matrix", "MatrixModels", "mgcv", "microbenchmark", "minqa", "modelr", "nlme", "nloptr", "nnet", "numDeriv", "pbkrtest", "pillar", "pkgconfig", "plotfunctions", "purrr", "quantreg", "R6", "rbibutils", "RColorBrewer", "Rcpp", "RcppArmadillo", "RcppEigen", "Rdpack", "reformulas", "rlang", "S7", "sandwich", "scales", "SparseM", "stringi", "stringr", "survival", "tibble", "tidyr", "tidyselect", "timeDate", "urca", "utf8", "vctrs", "viridisLite", "withr", "zoo" ], "_score": 2, "_indexed": false, "_nocasepkg": "mrchecks", "_universes": [ "mrcieu" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "0.0.0.9000", "date": "2026-06-05T06:29:05.000Z", "distro": "noble", "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "fileid": "a7054c8ef19d88643ebc5e965b9c55e8fca6ff3c3855ffee481184a20ec1500a", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673" }, { "r": "4.6.0", "os": "linux", "version": "0.0.0.9000", "date": "2026-06-05T06:29:03.000Z", "distro": "noble", "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "fileid": "2084f10d334ada4ea111f300ec72ad6208c7a67bd3e4121ef54ea042b8687ad0", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673" }, { "r": "4.5.3", "os": "mac", "version": "0.0.0.9000", "date": "2026-06-05T06:28:52.000Z", "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "fileid": "6884b936b22527dfcdab5ed52e03705381671813026f0287406ff954c233f882", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673" }, { "r": "4.6.0", "os": "mac", "version": "0.0.0.9000", "date": "2026-06-05T06:28:58.000Z", "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "fileid": "8cb86870fd4b31ed5e175a9aeb1525719b34f850452eb0e1734da0180fad78a5", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673" }, { "r": "4.6.0", "os": "wasm", "version": "0.0.0.9000", "date": "2026-06-05T06:29:03.000Z", "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "fileid": "4438f050737c7390e3195a3184447b1bb6b5eddd99b7883bd1b9e9642523c48a", "status": "success", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673" }, { "r": "4.7.0", "os": "win", "version": "0.0.0.9000", "date": "2026-06-05T06:28:12.000Z", "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "fileid": "e1ef9682ea51d0269d7d56b0dd06e9b8aeb4b4356597477b1bd1f29b59c54441", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673" }, { "r": "4.5.3", "os": "win", "version": "0.0.0.9000", "date": "2026-06-05T06:28:01.000Z", "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "fileid": "b36628f41999cd0ca06b7f6706ea60d5b67c49803a293af893c8db2435ddbcbb", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673" }, { "r": "4.6.0", "os": "win", "version": "0.0.0.9000", "date": "2026-06-05T06:28:18.000Z", "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42", "fileid": "1e1736ed760185bce5032a7c58a2aaadcee0f4b9c168458aa78500d5704a44e7", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26999187673" } ] }