{
  "_id": "6a49f4e17a98a23ad0a34c28",
  "Package": "MRchecks",
  "Title": "Tools for detecting genetic variants whose effect changes with\nage and associated bias",
  "Version": "0.0.0.9000",
  "Authors@R": "person(given = \"Jeremy\",\nfamily = \"Labrecque\",\nrole = c(\"aut\", \"cre\"),\nemail = \"j.labrecque@erasmusmc.nl\",\ncomment = c(ORCID = \"0000-0002-1028-2158\"))",
  "Description": "This package is a collection of tools to detect SNPs whose\neffect varies with age whose. owoeosds sd sd. sdsfw. sdfsers s\nes .",
  "License": "`use_mit_license()`, `use_gpl3_license()` or friends to pick a\nlicense",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "Roxygen": "list(markdown = TRUE)",
  "RoxygenNote": "7.1.1",
  "Config/pak/sysreqs": "cmake make libicu-dev",
  "Repository": "https://mrcieu.r-universe.dev",
  "Date/Publication": "2021-09-15 19:53:17 UTC",
  "RemoteUrl": "https://github.com/jalabrecque/MRchecks",
  "RemoteRef": "HEAD",
  "RemoteSha": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-07-05 05:57:09 UTC",
    "User": "root"
  },
  "Author": "Jeremy Labrecque [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-1028-2158>)",
  "Maintainer": "Jeremy Labrecque <j.labrecque@erasmusmc.nl>",
  "_user": "mrcieu",
  "_type": "src",
  "_file": "MRchecks_0.0.0.9000.tar.gz",
  "_fileid": "https://r2.ropensci.org/7ad22a2c826e57283e87a23971344989678dad182e852d94a023e979adab4499",
  "_filesize": 729003,
  "_sha256": "7ad22a2c826e57283e87a23971344989678dad182e852d94a023e979adab4499",
  "_expires": "2026-10-13T06:08:31.000Z",
  "_created": "2026-07-05T05:57:09.000Z",
  "_published": "2026-07-05T06:08:33.644Z",
  "_jobs": [
    {
      "job": 85197290720,
      "time": 139,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "8088828511"
    },
    {
      "job": 85197290730,
      "time": 136,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "WARNING",
      "artifact": "8088828077"
    },
    {
      "job": 85197290721,
      "time": 119,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "8088886764"
    },
    {
      "job": 85197290722,
      "time": 77,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "WARNING",
      "artifact": "8088892532"
    },
    {
      "job": 85197100774,
      "time": 192,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8088812035"
    },
    {
      "job": 85197290719,
      "time": 149,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "8088829597"
    },
    {
      "job": 85197290729,
      "time": 67,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "8088819855"
    },
    {
      "job": 85197290725,
      "time": 66,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "8088819829"
    },
    {
      "job": 85197290731,
      "time": 64,
      "config": "windows-release",
      "r": "4.6.1",
      "check": "WARNING",
      "artifact": "8088819598"
    }
  ],
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934",
  "_status": "success",
  "_upstream": "https://github.com/jalabrecque/MRchecks",
  "_commit": {
    "id": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
    "author": "Jeremy Labrecque <j.labrecque@erasmusmc.nl>",
    "committer": "GitHub <noreply@github.com>",
    "message": "Update README.md",
    "time": 1631735597
  },
  "_maintainer": {
    "name": "Jeremy Labrecque",
    "email": "j.labrecque@erasmusmc.nl",
    "login": "jalabrecque",
    "description": "Causal inference in epidemiologic studies. More specifically my current interests are in genetic epi, social epi and everything in between.",
    "uuid": 10617433,
    "orcid": "0000-0002-1028-2158"
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 2.10",
      "role": "Depends"
    },
    {
      "package": "mgcv",
      "role": "Imports"
    },
    {
      "package": "magrittr",
      "role": "Imports"
    },
    {
      "package": "dplyr",
      "role": "Imports"
    },
    {
      "package": "itsadug",
      "role": "Imports"
    },
    {
      "package": "AER",
      "role": "Imports"
    },
    {
      "package": "plotfunctions",
      "role": "Imports"
    }
  ],
  "_owner": "jalabrecque",
  "_selfowned": false,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_stars": 2,
  "_contributors": [
    {
      "user": "jalabrecque",
      "count": 35,
      "uuid": 10617433
    }
  ],
  "_userbio": {
    "uuid": 15654827,
    "type": "organization",
    "name": "MRC Integrative Epidemiology Unit",
    "followers": 250
  },
  "_downloads": {
    "count": 0,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/MRchecks"
  },
  "_devurl": "https://github.com/jalabrecque/mrchecks",
  "_searchresults": 0,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/MRchecks.html",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_cranurl": false,
  "_exports": [
    "%>%",
    "SNPxAGE_bias",
    "SNPxAGE_effect",
    "SNPxAGE_model",
    "SNPxAGE_plot"
  ],
  "_datasets": [
    {
      "name": "test_data",
      "title": "",
      "object": "test_data",
      "class": [
        "data.frame"
      ],
      "fields": [
        "age",
        "SNP",
        "y",
        "c"
      ],
      "rows": 10000,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "SNPxAGE_bias",
      "title": "Estimate bias from age-varying genetic effects in Mendelian randomization",
      "topics": [
        "SNPxAGE_bias"
      ]
    },
    {
      "page": "SNPxAGE_effect",
      "title": "Function to estimate the per-allele effect at each age",
      "topics": [
        "SNPxAGE_effect"
      ]
    },
    {
      "page": "SNPxAGE_model",
      "title": "Flexibly modeling the age/phenotype association by genetic variant",
      "topics": [
        "SNPxAGE_model"
      ]
    },
    {
      "page": "SNPxAGE_plot",
      "title": "Function to plot absolute value of pheontype for each genotype",
      "topics": [
        "SNPxAGE_plot"
      ]
    }
  ],
  "_readme": "https://github.com/jalabrecque/MRchecks/raw/HEAD/README.md",
  "_rundeps": [
    "abind",
    "AER",
    "backports",
    "boot",
    "broom",
    "car",
    "carData",
    "cli",
    "colorspace",
    "cowplot",
    "cpp11",
    "Deriv",
    "doBy",
    "dplyr",
    "farver",
    "forecast",
    "Formula",
    "fracdiff",
    "generics",
    "ggplot2",
    "glue",
    "gtable",
    "isoband",
    "itsadug",
    "labeling",
    "lattice",
    "lifecycle",
    "lme4",
    "lmtest",
    "magrittr",
    "MASS",
    "Matrix",
    "MatrixModels",
    "mgcv",
    "minqa",
    "modelr",
    "nlme",
    "nloptr",
    "nnet",
    "numDeriv",
    "pbkrtest",
    "pillar",
    "pkgconfig",
    "plotfunctions",
    "purrr",
    "quantreg",
    "R6",
    "rbibutils",
    "RColorBrewer",
    "Rcpp",
    "RcppArmadillo",
    "RcppEigen",
    "Rdpack",
    "reformulas",
    "rlang",
    "S7",
    "sandwich",
    "scales",
    "SparseM",
    "stringi",
    "stringr",
    "survival",
    "tibble",
    "tidyr",
    "tidyselect",
    "timeDate",
    "urca",
    "utf8",
    "vctrs",
    "viridisLite",
    "withr",
    "zoo"
  ],
  "_score": 2,
  "_indexed": false,
  "_nocasepkg": "mrchecks",
  "_universes": [
    "mrcieu"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.0.0.9000",
      "date": "2026-07-05T05:59:31.000Z",
      "distro": "resolute",
      "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
      "fileid": "https://r2.ropensci.org/d716e3c5f6b4f146a67f97aed42869f03e40f276a705e1aeb1d7e96e10aecc79",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "0.0.0.9000",
      "date": "2026-07-05T05:59:27.000Z",
      "distro": "resolute",
      "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
      "fileid": "https://r2.ropensci.org/4e2b8d75d9e12b8926562be3f84ef81fbcc27e00c4174921ef5c7178a744f952",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.0.0.9000",
      "date": "2026-07-05T06:07:20.000Z",
      "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
      "fileid": "https://r2.ropensci.org/98369143acc62366aa7d36a4ba0deb0a2918d608ca7d2eca10174089236bd3c9",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "0.0.0.9000",
      "date": "2026-07-05T06:08:07.000Z",
      "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
      "fileid": "https://r2.ropensci.org/840711cfa81335b0dcdafbbbdfa834e7544710d0b667e0c36f941d584ff82a22",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "0.0.0.9000",
      "date": "2026-07-05T05:59:51.000Z",
      "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
      "fileid": "https://r2.ropensci.org/fc56cbe1183dddc0ca4147bbe75799e818825dc658d2bf1b4da4fbb046bf0e14",
      "status": "success",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.0.0.9000",
      "date": "2026-07-05T05:58:15.000Z",
      "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
      "fileid": "https://r2.ropensci.org/9c7d93a378fe9acbea8596ebf8c223536f0339d36c4b5a9d55922041652723ec",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "0.0.0.9000",
      "date": "2026-07-05T05:58:16.000Z",
      "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
      "fileid": "https://r2.ropensci.org/cd88583602e1916caf18adf089bc2097c5efb646204136d6a6a692fc03db8363",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "0.0.0.9000",
      "date": "2026-07-05T05:58:13.000Z",
      "commit": "344ae2f7bbc03106c4a8bf9e50999b2e159d0d42",
      "fileid": "https://r2.ropensci.org/b99aa81c05e707e98cb9d4ffaca1f4e108aaa2f06306e2d6ffa4ef42425fa548",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/28731232934"
    }
  ]
}