{
  "_id": "6aa7bbf8089bafb098cf4dd8",
  "Package": "iGasso",
  "Type": "Package",
  "Encoding": "UTF-8",
  "Title": "Statistical Tests and Utilities for Genetic Association",
  "Version": "1.6.2",
  "Date": "2026-7-16",
  "Description": "A collection of statistical tests for genetic association\nstudies and summary data based Mendelian randomization.",
  "License": "GPL (>= 2)",
  "LazyLoad": "yes",
  "Config/roxygen2/version": "8.0.0",
  "Authors@R": "c(person(given = c(\"Dr.\", \"Kai\"),\nfamily = \"Wang\",\nrole = \"aut\",\nemail = \"kai-wang@uiowa.edu\"),\nperson(given = \"Kai\",\nfamily = \"Wang\",\nrole = \"cre\",\nemail = \"kai-wang@uiowa.edu\"))",
  "LazyData": "true",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-09-14 09:12:12 UTC",
    "User": "root"
  },
  "Author": "Dr. Kai Wang [aut], Kai Wang [cre]",
  "Maintainer": "Kai Wang <kai-wang@uiowa.edu>",
  "Config/pak/sysreqs": "cmake make",
  "Repository": "https://mrcieu.r-universe.dev",
  "Date/Publication": "2026-07-16 14:40:02 UTC",
  "RemoteUrl": "https://github.com/cran/iGasso",
  "RemoteRef": "HEAD",
  "RemoteSha": "43695c19248d434dd894766bcfc086e9aa3ab833",
  "_user": "mrcieu",
  "_type": "src",
  "_file": "iGasso_1.6.2.tar.gz",
  "_fileid": "https://r2.ropensci.org/56d7d525fb4221076af154f8881392002b9320e827c496acb40c6f38255ddadf",
  "_filesize": 517768,
  "_sha256": "56d7d525fb4221076af154f8881392002b9320e827c496acb40c6f38255ddadf",
  "_expires": "2026-12-23T09:18:46.000Z",
  "_created": "2026-09-14T09:12:12.000Z",
  "_published": "2026-10-14T08:39:07.083Z",
  "_jobs": [
    {
      "job": 103920347707,
      "time": 145,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "10340413991"
    },
    {
      "job": 103920347798,
      "time": 138,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10339793535"
    },
    {
      "job": 103920347846,
      "time": 105,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "10340327851"
    },
    {
      "job": 103920347747,
      "time": 66,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10340299658"
    },
    {
      "job": 103919411275,
      "time": 198,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10340468355"
    },
    {
      "job": 103920347741,
      "time": 135,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "10340029644"
    },
    {
      "job": 103920347789,
      "time": 84,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "10340307467"
    },
    {
      "job": 103920347814,
      "time": 87,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "10340184169"
    },
    {
      "job": 103920347763,
      "time": 89,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10340692735"
    }
  ],
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374",
  "_status": "success",
  "_upstream": "https://github.com/cran/iGasso",
  "_commit": {
    "id": "43695c19248d434dd894766bcfc086e9aa3ab833",
    "author": "Kai Wang <kai-wang@uiowa.edu>",
    "committer": "cran-robot <csardi.gabor+cran@gmail.com>",
    "message": "version 1.6.2\n",
    "time": 1784212802
  },
  "_maintainer": {
    "name": "Kai Wang",
    "email": "kai-wang@uiowa.edu"
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "lattice",
      "role": "Depends"
    },
    {
      "package": "CompQuadForm",
      "role": "Depends"
    },
    {
      "package": "MASS",
      "role": "Depends"
    },
    {
      "package": "MBESS",
      "role": "Depends"
    },
    {
      "package": "R",
      "version": ">= 3.5",
      "role": "Depends"
    }
  ],
  "_owner": "cran",
  "_selfowned": false,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2026-29",
      "n": 1
    }
  ],
  "_tags": [
    {
      "name": "1.6.2",
      "date": "2026-07-16"
    }
  ],
  "_stars": 0,
  "_userbio": {
    "uuid": 15654827,
    "type": "organization",
    "name": "MRC Integrative Epidemiology Unit",
    "followers": 255
  },
  "_downloads": {
    "count": 262,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/iGasso"
  },
  "_mentions": 1,
  "_searchresults": 6,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/iGasso.html",
    "extra/manual.pdf",
    "manual.pdf"
  ],
  "_realowner": "cran",
  "_cranurl": false,
  "_releases": [
    {
      "version": "1.0",
      "date": "2012-01-07"
    },
    {
      "version": "1.1",
      "date": "2012-08-21"
    },
    {
      "version": "1.1-1",
      "date": "2013-02-05"
    },
    {
      "version": "1.2",
      "date": "2014-06-18"
    },
    {
      "version": "1.3",
      "date": "2016-02-01"
    },
    {
      "version": "1.4",
      "date": "2016-06-04"
    },
    {
      "version": "1.6",
      "date": "2023-08-08"
    },
    {
      "version": "1.6.1",
      "date": "2024-03-12"
    },
    {
      "version": "1.6.2",
      "date": "2026-07-16"
    }
  ],
  "_exports": [
    "genome.plot",
    "h2_snp",
    "KAT_coin",
    "mBAplot",
    "MFree.test",
    "MR_het_test",
    "SKATplus",
    "SMR_interval",
    "tarq",
    "tssmr",
    "VSTF.test",
    "vvplot"
  ],
  "_datasets": [
    {
      "name": "bmi.cad",
      "title": "Effect of Body Mass Index (BMI) on Coronary Artery Disease (CAD)",
      "object": "bmi.cad",
      "class": [
        "data.table",
        "data.frame"
      ],
      "fields": [
        "SNP",
        "CHR.selection",
        "POS.selection",
        "other_allele.selection",
        "effect_allele.selection",
        "Frq.selection",
        "Rsq.selection",
        "beta.selection",
        "se.selection",
        "pval.selection",
        "eaf.selection",
        "id.selection",
        "effect_allele.exposure",
        "other_allele.exposure",
        "beta.exposure",
        "eaf.exposure",
        "se.exposure",
        "pval.exposure",
        "samplesize.exposure",
        "id.exposure",
        "effect_allele.outcome",
        "other_allele.outcome",
        "beta.outcome",
        "eaf.outcome",
        "id.outcome",
        "position.outcome",
        "reference_allele.outcome",
        "se.outcome",
        "pval.outcome",
        "n_cases_(stage2).outcome",
        "n_controls_(stage2).outcome",
        "het_pvalue_(stage2).outcome",
        "model(stage2).outcome",
        "Fisher_Pvalue.outcome",
        "N.outcome",
        "log_odds.outcome",
        "log_odds_se.outcome",
        "het_pvalue.outcome",
        "model.outcome",
        "InverseVariance_Pvalue.outcome",
        "samplesize.outcome",
        "mr_keep"
      ],
      "rows": 1119,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "iGasso-package",
      "title": "Statistical Tests and utilities for Genetic Association",
      "topics": [
        "iGasso-package",
        "iGasso"
      ]
    },
    {
      "page": "bmi.cad",
      "title": "Effect of Body Mass Index (BMI) on Coronary Artery Disease (CAD)",
      "topics": [
        "bmi.cad"
      ]
    },
    {
      "page": "genome.plot",
      "title": "Genome-wide Plot of a Variable",
      "topics": [
        "genome.plot"
      ]
    },
    {
      "page": "h2_snp",
      "title": "An exact method for SNP-heritability estimation using GWAS summary statistics",
      "topics": [
        "h2_snp"
      ]
    },
    {
      "page": "KAT_coin",
      "title": "Conditional Inference for the Kernel Association Test (KAT)",
      "topics": [
        "KAT_coin"
      ]
    },
    {
      "page": "mBAplot",
      "title": "Modified Bland-Altman plot for checking genetic homogeneity between two samples",
      "topics": [
        "mBAplot"
      ]
    },
    {
      "page": "MFree.test",
      "title": "Model-free Association Tests",
      "topics": [
        "MFree.test"
      ]
    },
    {
      "page": "MR_het_test",
      "title": "Test of Heterogeneity in MR using Principal Components",
      "topics": [
        "MR_het_test"
      ]
    },
    {
      "page": "SKATplus",
      "title": "A Gene- or Pathway-Based Test of Association 'SKATlus' provides enhanced power over SKAT by properly estimating the null distribution of SKAT.",
      "topics": [
        "SKATplus"
      ]
    },
    {
      "page": "SMR_interval",
      "title": "Interval Estimates for Summary Data Mendelian Randomization Analysis in the Presence of Winner's Curse",
      "topics": [
        "SMR_interval"
      ]
    },
    {
      "page": "tarq",
      "title": "An Accurate Normalization Method for High Throughput Sequencing Data",
      "topics": [
        "tarq"
      ]
    },
    {
      "page": "tssmr",
      "title": "Two-stage least squares estimator for two-sample summary statistics MR",
      "topics": [
        "tssmr"
      ]
    },
    {
      "page": "VSTF.test",
      "title": "Association Tests for Rare Variants Based on Variance-Stabilizing Transformation",
      "topics": [
        "VSTF.test"
      ]
    },
    {
      "page": "vvplot",
      "title": "V-V plot for checking genetic homogeneity between two samples",
      "topics": [
        "vvplot"
      ]
    }
  ],
  "_rundeps": [
    "abind",
    "arm",
    "BH",
    "boot",
    "cli",
    "coda",
    "CompQuadForm",
    "digest",
    "lattice",
    "lavaan",
    "lifecycle",
    "lme4",
    "MASS",
    "Matrix",
    "MBESS",
    "mi",
    "minqa",
    "mnormt",
    "mvtnorm",
    "nlme",
    "nloptr",
    "numDeriv",
    "OpenMx",
    "pbivnorm",
    "quadprog",
    "rbibutils",
    "Rcpp",
    "RcppEigen",
    "RcppParallel",
    "Rdpack",
    "reformulas",
    "rlang",
    "rpf",
    "sem",
    "semTools",
    "StanHeaders"
  ],
  "_score": 1,
  "_indexed": false,
  "_nocasepkg": "igasso",
  "_universes": [
    "mrcieu"
  ],
  "_indexurl": "https://cran.r-universe.dev/iGasso",
  "_progress_url": "https://github.com/r-universe/mrcieu/actions/runs/38536584416",
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.6.2",
      "date": "2026-09-14T09:14:37.000Z",
      "distro": "resolute",
      "commit": "43695c19248d434dd894766bcfc086e9aa3ab833",
      "fileid": "https://r2.ropensci.org/f139450be659f15d8422f5a03bd3b18452813350d50e082ea20bf2bf79a1237f",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.6.2",
      "date": "2026-09-14T09:14:32.000Z",
      "distro": "resolute",
      "commit": "43695c19248d434dd894766bcfc086e9aa3ab833",
      "fileid": "https://r2.ropensci.org/b0b92595eaa44e9cb74bf29fbf2346681ddc5a63e4eac862d8fb017cfd0d6005",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.6.2",
      "date": "2026-09-14T09:15:28.000Z",
      "commit": "43695c19248d434dd894766bcfc086e9aa3ab833",
      "fileid": "https://r2.ropensci.org/394d738748dfc2f6976f771b9f0b5f998904e4a55d0088d7c2580864a4195c80",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.6.2",
      "date": "2026-09-14T09:18:14.000Z",
      "commit": "43695c19248d434dd894766bcfc086e9aa3ab833",
      "fileid": "https://r2.ropensci.org/62aa128db27cefef92e5211294659744137b311b2bb67f6594aff9d60a365e0b",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.6.2",
      "date": "2026-09-14T09:14:40.000Z",
      "commit": "43695c19248d434dd894766bcfc086e9aa3ab833",
      "fileid": "https://r2.ropensci.org/43d12ea6f6b4870413bb5349e7c0fdd10b9c2f77bf5cf2cc6826cb0dfdba371c",
      "status": "success",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.6.2",
      "date": "2026-09-14T09:13:33.000Z",
      "commit": "43695c19248d434dd894766bcfc086e9aa3ab833",
      "fileid": "https://r2.ropensci.org/6c4baf2f1f8dc78566943d057f8f366bbe0ad85b2a4c874621b55c8b9e688bc9",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.6.2",
      "date": "2026-09-14T09:13:37.000Z",
      "commit": "43695c19248d434dd894766bcfc086e9aa3ab833",
      "fileid": "https://r2.ropensci.org/a7aed8ec16f62687eb8a19e773f036f89ac8802d61421906955d2b9437c51a5d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.6.2",
      "date": "2026-09-14T09:13:38.000Z",
      "commit": "43695c19248d434dd894766bcfc086e9aa3ab833",
      "fileid": "https://r2.ropensci.org/75afb6aa4234c8feef3fabf3039be405010d515aea0454daa4fbdf8408420164",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/34826353374"
    }
  ]
}