{ "_id": "6ac20365773a0037682c087c", "Type": "Package", "Package": "mrbayes", "Title": "Bayesian Summary Data Models for Mendelian Randomization Studies", "Version": "0.5.3.9000", "Authors@R": "c(\nperson(\"Okezie\", \"Uche-Ikonne\", , \"okezieikonne@gmail.com\", role = \"aut\",\ncomment = c(ORCID = \"0000-0002-8461-8099\")),\nperson(\"Frank\", \"Dondelinger\", , \"f.dondelinger@lancaster.ac.uk\", role = \"aut\",\ncomment = c(ORCID = \"0000-0003-1816-6300\")),\nperson(\"Tom\", \"Palmer\", , \"remlapmot@hotmail.com\", role = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0000-0003-4655-4511\"))\n)", "Description": "Bayesian estimation of inverse variance weighted (IVW),\nBurgess et al. (2013) , and MR-Egger,\nBowden et al. (2015) , summary data\nmodels for Mendelian randomization analyses.", "License": "GPL-3", "URL": "https://github.com/okezie94/mrbayes,\nhttps://okezie94.github.io/mrbayes/,\nhttps://mrcieu.r-universe.dev/mrbayes", "BugReports": "https://github.com/okezie94/mrbayes/issues", "Biarch": "true", "Config/roxygen2/markdown": "TRUE", "Config/roxygen2/version": "8.1.0", "Encoding": "UTF-8", "LazyData": "true", "SystemRequirements": "GNU make", "Config/pak/sysreqs": "cmake make libuv1-dev libssl-dev libx11-dev\nzlib1g-dev", "Repository": "https://mrcieu.r-universe.dev", "Date/Publication": "2026-10-04 06:17:12 UTC", "RemoteUrl": "https://github.com/okezie94/mrbayes", "RemoteRef": "HEAD", "RemoteSha": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-10-04 07:15:03 UTC", "User": "root" }, "Author": "Okezie Uche-Ikonne [aut] (ORCID:\n),\nFrank Dondelinger [aut] (ORCID:\n),\nTom Palmer [aut, cre] (ORCID: )", "Maintainer": "Tom Palmer ", "_user": "mrcieu", "_type": "src", "_file": "mrbayes_0.5.3.9000.tar.gz", "_fileid": "https://r2.ropensci.org/7f43dbc5fdffa51b4ca322db7f7aed7d69aad3bba2ab048e0cd1d8a45ccf714e", "_filesize": 203700, "_sha256": "7f43dbc5fdffa51b4ca322db7f7aed7d69aad3bba2ab048e0cd1d8a45ccf714e", "_expires": "2027-01-12T07:42:28.000Z", "_created": "2026-10-04T07:15:03.000Z", "_published": "2026-10-04T07:42:29.825Z", "_jobs": [ { "job": 111386110327, "time": 364, "config": "linux-devel-arm64", "r": "4.7.0", "check": "OK", "artifact": "11296967362" }, { "job": 111386110350, "time": 397, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "11296613384" }, { "job": 111386110351, "time": 383, "config": "linux-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "11297136823" }, { "job": 111386110338, "time": 450, "config": "linux-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "11297112057" }, { "job": 111386110344, "time": 439, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "11296644110" }, { "job": 111386110339, "time": 623, "config": "macos-oldrel-x86_64", "r": "4.5.3", "check": "OK", "artifact": "11296424196" }, { "job": 111386110315, "time": 344, "config": "macos-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "11297057809" }, { "job": 111386110354, "time": 645, "config": "macos-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "11297420827" }, { "job": 111384923802, "time": 482, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "11296602743" }, { "job": 111386110309, "time": 301, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "11296717936" }, { "job": 111386110365, "time": 472, "config": "windows-devel-arm64", "r": "4.7.0", "check": "OK", "artifact": "11297037431" }, { "job": 111386110342, "time": 578, "config": "windows-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "11296308805" }, { "job": 111386110360, "time": 625, "config": "windows-oldrel-x86_64", "r": "4.5.3", "check": "OK", "artifact": "11296433555" }, { "job": 111386110377, "time": 468, "config": "windows-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "11296762958" }, { "job": 111386110345, "time": 589, "config": "windows-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "11296479995" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749", "_status": "success", "_upstream": "https://github.com/okezie94/mrbayes", "_commit": { "id": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "author": "Tom Palmer ", "committer": "Tom Palmer ", "message": "Add build recipe\n", "time": 1791094632 }, "_maintainer": { "name": "Tom Palmer", "email": "remlapmot@hotmail.com", "login": "remlapmot", "orcid": "0000-0003-4655-4511", "description": "Averaging statistician ... ", "uuid": 3777473 }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 4.3.0", "role": "Depends" }, { "package": "BH", "version": ">= 1.66.0", "role": "LinkingTo" }, { "package": "Rcpp", "version": ">= 0.12.0", "role": "LinkingTo" }, { "package": "RcppEigen", "version": ">= 0.3.3.3.0", "role": "LinkingTo" }, { "package": "RcppParallel", "version": ">= 5.0.1", "role": "LinkingTo" }, { "package": "rstan", "version": ">= 2.18.1", "role": "LinkingTo" }, { "package": "StanHeaders", "version": ">= 2.18.0", "role": "LinkingTo" }, { "package": "DescTools", "role": "Imports" }, { "package": "methods", "role": "Imports" }, { "package": "Rcpp", "version": ">= 0.12.0", "role": "Imports" }, { "package": "RcppParallel", "version": ">= 5.0.1", "role": "Imports" }, { "package": "rstan", "version": ">= 2.18.1", "role": "Imports" }, { "package": "rstantools", "version": ">= 2.4.0", "role": "Imports" }, { "package": "MendelianRandomization", "role": "Suggests" }, { "package": "rjags", "version": ">= 4-9", "role": "Suggests" }, { "package": "testthat", "role": "Suggests" } ], "_owner": "okezie94", "_selfowned": true, "_usedby": 0, "_updates": [ { "week": "2025-48", "n": 1 }, { "week": "2025-49", "n": 1 }, { "week": "2026-12", "n": 7 }, { "week": "2026-18", "n": 7 }, { "week": "2026-19", "n": 8 }, { "week": "2026-20", "n": 6 }, { "week": "2026-21", "n": 3 }, { "week": "2026-22", "n": 8 }, { "week": "2026-26", "n": 3 }, { "week": "2026-28", "n": 17 }, { "week": "2026-31", "n": 1 }, { "week": "2026-32", "n": 3 }, { "week": "2026-35", "n": 1 }, { "week": "2026-40", "n": 2 } ], "_tags": [ { "name": "v0.5.3", "date": "2026-07-08" } ], "_stars": 5, "_contributors": [ { "user": "remlapmot", "count": 472, "uuid": 3777473 }, { "user": "okezie94", "count": 57, "uuid": 42736755 }, { "user": "olivroy", "count": 1, "uuid": 52606734 } ], "_userbio": { "uuid": 15654827, "type": "organization", "name": "MRC Integrative Epidemiology Unit", "followers": 257 }, "_downloads": { "count": 449, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/mrbayes" }, "_mentions": 48, "_devurl": "https://github.com/okezie94/mrbayes", "_pkgdown": "https://okezie94.github.io/mrbayes/", "_searchresults": 9, "_topics": [ "onetbb", "cpp" ], "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/manual.pdf", "extra/mrbayes.html", "extra/NEWS.html", "extra/NEWS.txt", "extra/readme.html", "extra/readme.md" ], "_homeurl": "https://github.com/okezie94/mrbayes", "_realowner": "okezie94", "_cranurl": true, "_releases": [ { "version": "0.1.0", "date": "2019-09-04" }, { "version": "0.2.0", "date": "2020-05-28" }, { "version": "0.3.0", "date": "2021-04-01" }, { "version": "0.4.0", "date": "2021-07-13" }, { "version": "0.5.0", "date": "2021-09-21" }, { "version": "0.5.1", "date": "2021-10-02" }, { "version": "0.5.2", "date": "2024-08-19" }, { "version": "0.5.3", "date": "2026-07-08" } ], "_exports": [ "mr_egger_rjags", "mr_egger_stan", "mr_format", "mr_ivw_rjags", "mr_ivw_stan", "mr_radialegger_rjags", "mr_radialegger_stan", "mrinput_mr_format", "mvmr_egger_rjags", "mvmr_egger_stan", "mvmr_format", "mvmr_ivw_rjags", "mvmr_ivw_stan" ], "_datasets": [ { "name": "bmi_insulin", "title": "Dataset from Richmond et al. 2017 investigating the association of BMI on insulin resistance", "object": "bmi_insulin", "class": [ "data.frame", "mr_format" ], "fields": [ "rsid", "beta.exposure", "beta.outcome", "se.exposure", "se.outcome" ], "rows": 14, "table": true, "tojson": true }, { "name": "dodata", "title": "Dataset from Do et al., Nat Gen, 2013 containing summary level data on associations of genotypes with lipid traits and the risk of coronary heart diseases", "object": "dodata", "class": [ "data.frame" ], "fields": [ "rsid", "a1", "a2", "chr", "pos", "ldlcbeta", "hdlcbeta", "tgbeta", "chdbeta", "ldlcp2", "hdlcp2", "tgp2", "chdp2", "ldlcz", "ldlcse", "hdlcz", "hdlcse", "tgz", "tgse", "chdz", "chdse" ], "rows": 185, "table": true, "tojson": true } ], "_help": [ { "page": "mrbayes-package", "title": "mrbayes: Bayesian implementation of the IVW and MR-Egger models for two-sample Mendelian randomization analyses", "topics": [ "mrbayes-package", "mrbayes" ] }, { "page": "bmi_insulin", "title": "Dataset from Richmond et al. 2017 investigating the association of BMI on insulin resistance", "topics": [ "bmi_insulin" ] }, { "page": "dodata", "title": "Dataset from Do et al., Nat Gen, 2013 containing summary level data on associations of genotypes with lipid traits and the risk of coronary heart diseases", "topics": [ "dodata" ] }, { "page": "mr_egger_rjags", "title": "Bayesian implementation of the MR-Egger multivariate model with choice of prior distributions fitted using JAGS.", "topics": [ "mr_egger_rjags" ] }, { "page": "mr_egger_stan", "title": "Bayesian inverse variance weighted model with a choice of prior distributions fitted using Stan", "topics": [ "mr_egger_stan" ] }, { "page": "mr_format", "title": "Organises the summary level data for use in the Bayesian MR functions", "topics": [ "mr_format" ] }, { "page": "mr_ivw_rjags", "title": "Bayesian inverse variance weighted model with a choice of prior distributions fitted using JAGS.", "topics": [ "mr_ivw_rjags" ] }, { "page": "mr_ivw_stan", "title": "Bayesian inverse variance weighted model with a choice of prior distributions fitted using RStan.", "topics": [ "mr_ivw_stan" ] }, { "page": "mr_radialegger_rjags", "title": "Bayesian radial MR-Egger model with a choice of prior distributions fitted using JAGS.", "topics": [ "mr_radialegger_rjags" ] }, { "page": "mr_radialegger_stan", "title": "Bayesian inverse variance weighted model with a choice of prior distributions fitted using RStan.", "topics": [ "mr_radialegger_stan" ] }, { "page": "mrinput_mr_format", "title": "Convert an object of class MRInput from the MendelianRandomization package to the mrbayes mr_format class", "topics": [ "mrinput_mr_format" ] }, { "page": "mvmr_egger_rjags", "title": "Bayesian implementation of the MVMR-Egger model with choice of prior distributions fitted using JAGS.", "topics": [ "mvmr_egger_rjags" ] }, { "page": "mvmr_egger_stan", "title": "Bayesian implementation of the MVMR-Egger model with choice of prior distributions fitted using RStan.", "topics": [ "mvmr_egger_stan" ] }, { "page": "mvmr_format", "title": "Organises the summary level data for use in the Bayesian MR functions", "topics": [ "mvmr_format" ] }, { "page": "mvmr_ivw_rjags", "title": "Bayesian multivariate inverse variance weighted model with a choice of prior distributions fitted using JAGS.", "topics": [ "mvmr_ivw_rjags" ] }, { "page": "mvmr_ivw_stan", "title": "Bayesian multivariate inverse variance weighted model with a choice of prior distributions fitted using RStan.", "topics": [ "mvmr_ivw_stan" ] } ], "_readme": "https://github.com/okezie94/mrbayes/raw/HEAD/README.md", "_rundeps": [ "abind", "askpass", "backports", "BH", "bit", "bit64", "boot", "callr", "cellranger", "checkmate", "class", "cli", "clipr", "cpp11", "crayon", "curl", "data.table", "desc", "DescTools", "distributional", "e1071", "Exact", "expm", "farver", "forcats", "fs", "generics", "ggplot2", "gld", "glue", "gridExtra", "gtable", "haven", "hms", "httr", "inline", "isoband", "jsonlite", "labeling", "lattice", "lifecycle", "lmom", "loo", "magrittr", "MASS", "Matrix", "matrixStats", "mime", "mvtnorm", "numDeriv", "openssl", "otel", "pillar", "pkgbuild", "pkgconfig", "posterior", "prettyunits", "processx", "progress", "proxy", "ps", "QuickJSR", "R6", "RColorBrewer", "Rcpp", "RcppEigen", "RcppParallel", "readr", "readxl", "rematch", "rlang", "rootSolve", "rstan", "rstantools", "rstudioapi", "S7", "scales", "StanHeaders", "sys", "tensorA", "tibble", "tidyselect", "tzdb", "utf8", "vctrs", "viridisLite", "vroom", "withr" ], "_sysdeps": [ { "shlib": "libtbb", "package": "libtbb12", "headers": "libtbb-dev", "source": "onetbb", "version": "2022.3.0-2", "name": "onetbb", "homepage": "https://uxlfoundation.github.io/oneTBB/", "description": "parallelism library for C++ - runtime files" }, { "shlib": "libstdc++", "package": "libstdc++6", "source": "gcc", "version": "16-20260322-1ubuntu1", "name": "c++", "homepage": "http://gcc.gnu.org/", "description": "GNU Standard C++ Library v3" } ], "_score": 5.845098040014257, "_indexed": true, "_nocasepkg": "mrbayes", "_universes": [ "mrcieu", "remlapmot", "okezie94" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "0.5.3.9000", "date": "2026-10-04T07:20:34.000Z", "distro": "resolute", "arch": "aarch64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/abe74931da343583a49e34297caef6a27017d0a134c38b647a2654b66a879776", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.7.0", "os": "linux", "version": "0.5.3.9000", "date": "2026-10-04T07:20:59.000Z", "distro": "resolute", "arch": "x86_64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/f8b8516231c3ed2b7691013fb2ed4451f562f017a098e0b267b47a924f01d2ed", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.6.1", "os": "linux", "version": "0.5.3.9000", "date": "2026-10-04T07:20:42.000Z", "distro": "resolute", "arch": "aarch64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/9fb33ade3439c09f43b55e229372d4ef3d00595f260df2d5fff39596fc001cb0", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.6.1", "os": "linux", "version": "0.5.3.9000", "date": "2026-10-04T07:21:04.000Z", "distro": "resolute", "arch": "x86_64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/d69b880875c77388fcadaee533ba29a2c3137bfc7e30ed05269b9f15ab6c93b3", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.5.3", "os": "mac", "version": "0.5.3.9000", "date": "2026-10-04T07:27:30.000Z", "arch": "aarch64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/ee410dbf15fb15a5b56757f97bcfe588ec266dc6671c972e776e0f41089c6909", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.5.3", "os": "mac", "version": "0.5.3.9000", "date": "2026-10-04T07:33:00.000Z", "arch": "x86_64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/db672480039ef9ef3ee1da23c4b792955e5331d9286f0f4a7b0065f7117822c9", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.6.1", "os": "mac", "version": "0.5.3.9000", "date": "2026-10-04T07:27:00.000Z", "arch": "aarch64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/66b13d0535f151a7d5fa9383c0a2643cdd335e469ce07d50fd070d80d8913dc4", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.6.1", "os": "mac", "version": "0.5.3.9000", "date": "2026-10-04T07:35:01.000Z", "arch": "x86_64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/77b96efcba5ce5cac5748f431c2d162049a87f01c64c1333cf6ece58b30fc29e", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.6.0", "os": "wasm", "version": "0.5.3.9000", "date": "2026-10-04T07:20:56.000Z", "arch": "emscripten", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/63efb86834370f73dce8ec78a3939d3e4743dcce77bdc3dbe94e58b22fb27d7a", "status": "success", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.7.0", "os": "win", "version": "0.5.3.9000", "date": "2026-10-04T07:22:04.000Z", "arch": "aarch64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/641df15d4d5720362306534bf25af4a7e10730d8f7098ca26f2ae6944b2f24c8", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.7.0", "os": "win", "version": "0.5.3.9000", "date": "2026-10-04T07:19:53.000Z", "arch": "x86_64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/700d539c2f5ff91d3890b50eb71fc5d9d7fa786c45ebfa71a5b444bf1f33123b", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.5.3", "os": "win", "version": "0.5.3.9000", "date": "2026-10-04T07:20:00.000Z", "arch": "x86_64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/c96e651b247d3410bc1fffd324eab4bd306220a748c9f07280eaf5e5cab66ced", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.6.1", "os": "win", "version": "0.5.3.9000", "date": "2026-10-04T07:22:18.000Z", "arch": "aarch64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/6a4ed04b11f0167330a2a87f20ca4e3db7f4f769ac0600074b5c802c8fba73cc", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" }, { "r": "4.6.1", "os": "win", "version": "0.5.3.9000", "date": "2026-10-04T07:20:06.000Z", "arch": "x86_64", "commit": "369a5d4599e7f6f64b03840bdbfef8973c8aca70", "fileid": "https://r2.ropensci.org/d55dbaf6f7a73c63a86c25fa75f80fdc32955518d37d76899f7dc6128e4e15f9", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/37184964749" } ] }