{
  "_id": "6a1d3e001d7bb097a0a4015e",
  "Package": "winnerscurse",
  "Type": "Package",
  "Title": "Winner's Curse Adjustment Methods for Summary Statistics from\nGenome-Wide Association Studies",
  "Version": "0.1.1",
  "Authors@R": "person(\"Amanda\", \"Forde\", email = \"a.forde21@universityofgalway.ie\",\nrole = c(\"aut\", \"cre\"),  comment = c(ORCID = \"0000-0002-7940-3413\"))",
  "Description": "Designed to provide users with easy access to published\nmethods which aim to correct for Winner's Curse using only\nsummary statistics from genome-wide association studies. With\nmerely estimates of effect size and associated standard error\nfor each genetic variant, users are able to implement these\nmethods to obtain more accurate estimates of the true effect\nsizes. These methods can be applied to data from both\nquantitative and binary traits.",
  "License": "MIT + file LICENSE",
  "URL": "https://amandaforde.github.io/winnerscurse/",
  "Encoding": "UTF-8",
  "RoxygenNote": "7.2.3",
  "VignetteBuilder": "knitr",
  "Repository": "https://mrcieu.r-universe.dev",
  "Date/Publication": "2024-03-07 12:08:54 UTC",
  "RemoteUrl": "https://github.com/amandaforde/winnerscurse",
  "RemoteRef": "HEAD",
  "RemoteSha": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-06-01 08:03:55 UTC",
    "User": "root"
  },
  "Author": "Amanda Forde [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-7940-3413>)",
  "Maintainer": "Amanda Forde <a.forde21@universityofgalway.ie>",
  "MD5sum": "dd16c76efc62f968dc6eeb2bdc8d6b03",
  "_user": "mrcieu",
  "_type": "src",
  "_file": "winnerscurse_0.1.1.tar.gz",
  "_fileid": "5ad7d75939c08a2bc519916ba8c18d998eea5809acaf197e975cc373aaa19e14",
  "_filesize": 206166,
  "_sha256": "5ad7d75939c08a2bc519916ba8c18d998eea5809acaf197e975cc373aaa19e14",
  "_created": "2026-06-01T08:03:55.000Z",
  "_published": "2026-06-01T08:08:32.717Z",
  "_distro": "noble",
  "_jobs": [
    {
      "job": 78810632254,
      "time": 238,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7326375960"
    },
    {
      "job": 78810632291,
      "time": 236,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7326375406"
    },
    {
      "job": 78810632258,
      "time": 161,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7326350903"
    },
    {
      "job": 78810632438,
      "time": 226,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7326371548"
    },
    {
      "job": 78809893740,
      "time": 295,
      "config": "source",
      "r": "4.6.0",
      "check": "ERROR",
      "artifact": "7326299603"
    },
    {
      "job": 78810632224,
      "time": 112,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7326335939"
    },
    {
      "job": 78810632240,
      "time": 143,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7326345496"
    },
    {
      "job": 78810632353,
      "time": 218,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7326369466"
    },
    {
      "job": 78810632325,
      "time": 206,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7326365587"
    }
  ],
  "_buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253",
  "_status": "failure",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/amandaforde/winnerscurse",
  "_commit": {
    "id": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
    "author": "GenDataSci025 <GenDataSci025@NUIG-7CN1P53.uds.nuigalway.ie>",
    "committer": "GenDataSci025 <GenDataSci025@NUIG-7CN1P53.uds.nuigalway.ie>",
    "message": "minor adjust UMVCUE 5/3\n",
    "time": 1709813334
  },
  "_maintainer": {
    "name": "Amanda Forde",
    "email": "a.forde21@universityofgalway.ie",
    "orcid": "0000-0002-7940-3413"
  },
  "_registered": true,
  "_dependencies": [
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "dplyr",
      "role": "Imports"
    },
    {
      "package": "scam",
      "role": "Imports"
    },
    {
      "package": "mgcv",
      "role": "Imports"
    },
    {
      "package": "testthat",
      "role": "Suggests"
    },
    {
      "package": "knitr",
      "version": ">= 1.34",
      "role": "Suggests"
    },
    {
      "package": "markdown",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "version": ">= 2.11",
      "role": "Suggests"
    },
    {
      "package": "RColorBrewer",
      "role": "Suggests"
    },
    {
      "package": "ggplot2",
      "role": "Suggests"
    }
  ],
  "_owner": "amandaforde",
  "_selfowned": false,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_stars": 5,
  "_contributors": [
    {
      "user": "amandaforde",
      "count": 147,
      "uuid": 71341197
    }
  ],
  "_userbio": {
    "uuid": 15654827,
    "type": "organization",
    "name": "MRC Integrative Epidemiology Unit"
  },
  "_downloads": {
    "count": 0,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/winnerscurse"
  },
  "_devurl": "https://github.com/amandaforde/winnerscurse",
  "_pkgdown": "https://amandaforde.github.io/winnerscurse/",
  "_searchresults": 4,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/readme.html",
    "extra/readme.md",
    "extra/winnerscurse.html",
    "manual.pdf"
  ],
  "_cranurl": false,
  "_exports": [
    "BR_ss",
    "cl_interval",
    "conditional_likelihood",
    "condlike_rep",
    "empirical_bayes",
    "FDR_IQT",
    "MSE_minimizer",
    "se_adjust",
    "sim_stats",
    "UMVCUE"
  ],
  "_help": [
    {
      "page": "winnerscurse-package",
      "title": "winnerscurse: Winner's Curse Adjustment Methods for Summary Statistics from Genome-Wide Association Studies",
      "topics": [
        "winnerscurse-package",
        "winnerscurse"
      ]
    },
    {
      "page": "BR_ss",
      "title": "Bootstrap method for use with discovery GWAS",
      "topics": [
        "BR_ss"
      ]
    },
    {
      "page": "cl_interval",
      "title": "Confidence interval associated with discovery GWAS conditional likelihood methods",
      "topics": [
        "cl_interval"
      ]
    },
    {
      "page": "conditional_likelihood",
      "title": "Conditional likelihood methods for use with discovery GWAS",
      "topics": [
        "conditional_likelihood"
      ]
    },
    {
      "page": "condlike_rep",
      "title": "Conditional likelihood method for use with discovery and replication GWASs",
      "topics": [
        "condlike_rep"
      ]
    },
    {
      "page": "empirical_bayes",
      "title": "Empirical Bayes method for use with discovery GWAS",
      "topics": [
        "empirical_bayes"
      ]
    },
    {
      "page": "FDR_IQT",
      "title": "FDR IQT method for use with discovery GWAS",
      "topics": [
        "FDR_IQT"
      ]
    },
    {
      "page": "MSE_minimizer",
      "title": "MSE minimization method for use with discovery and replication GWASs",
      "topics": [
        "MSE_minimizer"
      ]
    },
    {
      "page": "se_adjust",
      "title": "Standard errors of adjusted discovery GWAS estimates via parametric bootstrap",
      "topics": [
        "se_adjust"
      ]
    },
    {
      "page": "sim_stats",
      "title": "Simulating GWAS summary statistics",
      "topics": [
        "sim_stats"
      ]
    },
    {
      "page": "UMVCUE",
      "title": "UMVCUE method for use with discovery and replication GWASs",
      "topics": [
        "UMVCUE"
      ]
    }
  ],
  "_readme": "https://github.com/amandaforde/winnerscurse/raw/HEAD/README.md",
  "_rundeps": [
    "cli",
    "dplyr",
    "generics",
    "glue",
    "lattice",
    "lifecycle",
    "magrittr",
    "Matrix",
    "mgcv",
    "nlme",
    "pillar",
    "pkgconfig",
    "R6",
    "rlang",
    "scam",
    "tibble",
    "tidyselect",
    "utf8",
    "vctrs",
    "withr"
  ],
  "_score": 2.3979400086720375,
  "_indexed": false,
  "_nocasepkg": "winnerscurse",
  "_universes": [
    "mrcieu"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.1.1",
      "date": "2026-06-01T08:06:00.000Z",
      "distro": "noble",
      "commit": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
      "fileid": "899760904806a73d7def74924cf65574609308d72bd25345aa66253a649dd660",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "0.1.1",
      "date": "2026-06-01T08:06:00.000Z",
      "distro": "noble",
      "commit": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
      "fileid": "628953a6f8e53fca75bd1bf4f3844762511fd6b7701f3786f89e4f78e1197252",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.1.1",
      "date": "2026-06-01T08:05:19.000Z",
      "commit": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
      "fileid": "4b51b521e60effa5cbb3cea7d1b09d43f8862559525247eb5f00cad5468fa9eb",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "0.1.1",
      "date": "2026-06-01T08:05:53.000Z",
      "commit": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
      "fileid": "3fd2e5d969e90735ca5da6a3f658e6178643604e0c057b2e9a448d6dbf9819b1",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "0.1.1",
      "date": "2026-06-01T08:06:02.000Z",
      "commit": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
      "fileid": "4c443724671f451d84fe72381505b144fda27e6c2148b9ba6df4c9412f87f267",
      "status": "success",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.1.1",
      "date": "2026-06-01T08:05:04.000Z",
      "commit": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
      "fileid": "5029e8b61996d972409fa606273eee11d9bafcd2204913f99b5da60ea83b616e",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "0.1.1",
      "date": "2026-06-01T08:05:22.000Z",
      "commit": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
      "fileid": "0155084158644687f3b4a5e83a118a87cc712d28125e4d815c650f38a79fefb7",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "0.1.1",
      "date": "2026-06-01T08:05:06.000Z",
      "commit": "2ed00bb119a5445e6a2985c0b6bf37a3068b9560",
      "fileid": "b60f8e48d8c363bb33436743c2b74593d46e584ad36a3ae125579e508e5b0e96",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/mrcieu/actions/runs/26742552253"
    }
  ]
}