{"pvalue":0.375,"sign":-1,"group":"AB1: Infectious diseases","label":"Actinomycosis","text":"Phenotype: Actinomycosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.375
N cases: 93
N controls: 332343"}
{"pvalue":0.0506,"sign":1,"group":"AB1: Infectious diseases","label":"Amoebiasis","text":"Phenotype: Amoebiasis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0506
N cases: 149
N controls: 336396"}
{"pvalue":0.112,"sign":1,"group":"AB1: Infectious diseases","label":"Anogenital herpesviral [herpes simplex] infection","text":"Phenotype: Anogenital herpesviral [herpes simplex] infection
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.112
N cases: 1812
N controls: 366340"}
{"pvalue":0.287,"sign":-1,"group":"AB1: Infectious diseases","label":"Aspergillosis","text":"Phenotype: Aspergillosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.287
N cases: 194
N controls: 369098"}
{"pvalue":0.0352,"sign":-1,"group":"AB1: Infectious diseases","label":"Atypical virus infections of central nervous system","text":"Phenotype: Atypical virus infections of central nervous system
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0352
N cases: 260
N controls: 375157"}
{"pvalue":0.0113,"sign":1,"group":"AB1: Infectious diseases","label":"Bacterial, viral and other infectious agents","text":"Phenotype: Bacterial, viral and other infectious agents
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0113
N cases: 2591
N controls: 374686"}
{"pvalue":0.0157,"sign":-1,"group":"AB1: Infectious diseases","label":"Bacterial infection, other or unspecified","text":"Phenotype: Bacterial infection, other or unspecified
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0157
N cases: 18576
N controls: 332343"}
{"pvalue":0.656,"sign":1,"group":"AB1: Infectious diseases","label":"Other bacterial intestinal infections","text":"Phenotype: Other bacterial intestinal infections
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.656
N cases: 5631
N controls: 336396"}
{"pvalue":0.606,"sign":-1,"group":"AB1: Infectious diseases","label":"Candidiasis","text":"Phenotype: Candidiasis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.606
N cases: 3974
N controls: 369098"}
{"pvalue":0.697,"sign":-1,"group":"AB1: Infectious diseases","label":"Other sexually transmitted chlamydial diseases","text":"Phenotype: Other sexually transmitted chlamydial diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.697
N cases: 2011
N controls: 366340"}
{"pvalue":0.0636,"sign":1,"group":"AB1: Infectious diseases","label":"Cholera","text":"Phenotype: Cholera
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0636
N cases: 1290
N controls: 336396"}
{"pvalue":0.425,"sign":-1,"group":"AB1: Infectious diseases","label":"Dermatophytosis","text":"Phenotype: Dermatophytosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.425
N cases: 3554
N controls: 369098"}
{"pvalue":0.0693,"sign":1,"group":"AB1: Infectious diseases","label":"Early syphilis","text":"Phenotype: Early syphilis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0693
N cases: 286
N controls: 366340"}
{"pvalue":0.35,"sign":1,"group":"AB1: Infectious diseases","label":"Infectious mononucleosis","text":"Phenotype: Infectious mononucleosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.35
N cases: 2353
N controls: 367472"}
{"pvalue":0.396,"sign":-1,"group":"AB1: Infectious diseases","label":"Enterobiasis","text":"Phenotype: Enterobiasis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.396
N cases: 98
N controls: 376807"}
{"pvalue":0.518,"sign":1,"group":"AB1: Infectious diseases","label":"Erysipelas","text":"Phenotype: Erysipelas
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.518
N cases: 20470
N controls: 332343"}
{"pvalue":0.717,"sign":-1,"group":"AB1: Infectious diseases","label":"Diarrhoea and gastroenteritis of presumed infectious origin","text":"Phenotype: Diarrhoea and gastroenteritis of presumed infectious origin
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.717
N cases: 29401
N controls: 336396"}
{"pvalue":0.319,"sign":-1,"group":"AB1: Infectious diseases","label":"Gonococcal infection","text":"Phenotype: Gonococcal infection
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.319
N cases: 878
N controls: 366340"}
{"pvalue":0.972,"sign":-1,"group":"AB1: Infectious diseases","label":"Helminthiases","text":"Phenotype: Helminthiases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.972
N cases: 470
N controls: 376807"}
{"pvalue":0.275,"sign":-1,"group":"AB1: Infectious diseases","label":"Acute hepatitis A","text":"Phenotype: Acute hepatitis A
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.275
N cases: 118
N controls: 375134"}
{"pvalue":0.184,"sign":1,"group":"AB1: Infectious diseases","label":"Acute hepatitis B","text":"Phenotype: Acute hepatitis B
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.184
N cases: 110
N controls: 375134"}
{"pvalue":0.136,"sign":1,"group":"AB1: Infectious diseases","label":"Herpesviral [herpes simplex] infections","text":"Phenotype: Herpesviral [herpes simplex] infections
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.136
N cases: 3374
N controls: 362997"}
{"pvalue":0.168,"sign":1,"group":"AB1: Infectious diseases","label":"Unspecified human immunodeficiency virus [HIV] disease","text":"Phenotype: Unspecified human immunodeficiency virus [HIV] disease
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.168
N cases: 245
N controls: 376773"}
{"pvalue":0.755,"sign":-1,"group":"AB1: Infectious diseases","label":"Intestinal infectious diseases","text":"Phenotype: Intestinal infectious diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.755
N cases: 40881
N controls: 336396"}
{"pvalue":0.503,"sign":-1,"group":"AB1: Infectious diseases","label":"Late syphilis","text":"Phenotype: Late syphilis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.503
N cases: 347
N controls: 366340"}
{"pvalue":0.342,"sign":1,"group":"AB1: Infectious diseases","label":"Listeriosis","text":"Phenotype: Listeriosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.342
N cases: 117
N controls: 332343"}
{"pvalue":0.29,"sign":-1,"group":"AB1: Infectious diseases","label":"Malaria","text":"Phenotype: Malaria
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.29
N cases: 129
N controls: 376614"}
{"pvalue":0.119,"sign":-1,"group":"AB1: Infectious diseases","label":"Measles","text":"Phenotype: Measles
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.119
N cases: 319
N controls: 362997"}
{"pvalue":0.499,"sign":-1,"group":"AB1: Infectious diseases","label":"Meningococcal infection","text":"Phenotype: Meningococcal infection
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.499
N cases: 215
N controls: 332343"}
{"pvalue":0.386,"sign":1,"group":"AB1: Infectious diseases","label":"Mumps","text":"Phenotype: Mumps
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.386
N cases: 744
N controls: 367472"}
{"pvalue":0.388,"sign":-1,"group":"AB1: Infectious diseases","label":"Mycoses","text":"Phenotype: Mycoses
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.388
N cases: 8179
N controls: 369098"}
{"pvalue":0.388,"sign":-1,"group":"AB1: Infectious diseases","label":"Other bacterial diseases","text":"Phenotype: Other bacterial diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.388
N cases: 44934
N controls: 332343"}
{"pvalue":0.742,"sign":-1,"group":"AB1: Infectious diseases","label":"Other bacterial agents as the cause of diseases classified to other chapters","text":"Phenotype: Other bacterial agents as the cause of diseases classified to other chapters
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.742
N cases: 259
N controls: 374686"}
{"pvalue":0.602,"sign":-1,"group":"AB1: Infectious diseases","label":"Other cestode infections","text":"Phenotype: Other cestode infections
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.602
N cases: 94
N controls: 376807"}
{"pvalue":0.387,"sign":1,"group":"AB1: Infectious diseases","label":"Other diseases caused by chlamydiae","text":"Phenotype: Other diseases caused by chlamydiae
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.387
N cases: 314
N controls: 376963"}
{"pvalue":0.238,"sign":1,"group":"AB1: Infectious diseases","label":"Human immunodeficiency virus [HIV] disease resulting in other conditions","text":"Phenotype: Human immunodeficiency virus [HIV] disease resulting in other conditions
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.238
N cases: 459
N controls: 376773"}
{"pvalue":0.924,"sign":-1,"group":"AB1: Infectious diseases","label":"Other infectious diseases","text":"Phenotype: Other infectious diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.924
N cases: 2347
N controls: 374930"}
{"pvalue":0.32,"sign":1,"group":"AB1: Infectious diseases","label":"Infection due to other mycobacteria","text":"Phenotype: Infection due to other mycobacteria
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.32
N cases: 395
N controls: 332343"}
{"pvalue":0.564,"sign":-1,"group":"AB1: Infectious diseases","label":"Other protozoal intestinal diseases","text":"Phenotype: Other protozoal intestinal diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.564
N cases: 336
N controls: 336396"}
{"pvalue":0.134,"sign":-1,"group":"AB1: Infectious diseases","label":"Other septicaemia","text":"Phenotype: Other septicaemia
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.134
N cases: 12301
N controls: 332343"}
{"pvalue":0.0404,"sign":1,"group":"AB1: Infectious diseases","label":"Other spirochaetal diseases","text":"Phenotype: Other spirochaetal diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0404
N cases: 2292
N controls: 374985"}
{"pvalue":0.464,"sign":-1,"group":"AB1: Infectious diseases","label":"Other superficial mycoses","text":"Phenotype: Other superficial mycoses
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.464
N cases: 491
N controls: 369098"}
{"pvalue":0.99,"sign":1,"group":"AB1: Infectious diseases","label":"Other viral diseases","text":"Phenotype: Other viral diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.99
N cases: 9805
N controls: 367472"}
{"pvalue":0.218,"sign":1,"group":"AB1: Infectious diseases","label":"Unspecified parasitic disease","text":"Phenotype: Unspecified parasitic disease
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.218
N cases: 223
N controls: 375759"}
{"pvalue":0.923,"sign":-1,"group":"AB1: Infectious diseases","label":"Pediculosis, acariasis and other infestations","text":"Phenotype: Pediculosis, acariasis and other infestations
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.923
N cases: 1518
N controls: 375759"}
{"pvalue":0.676,"sign":1,"group":"AB1: Infectious diseases","label":"Pediculosis and phthiriasis","text":"Phenotype: Pediculosis and phthiriasis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.676
N cases: 81
N controls: 375759"}
{"pvalue":0.958,"sign":-1,"group":"AB1: Infectious diseases","label":"Pneumocystosis","text":"Phenotype: Pneumocystosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.958
N cases: 353
N controls: 376614"}
{"pvalue":0.0187,"sign":-1,"group":"AB1: Infectious diseases","label":"Acute poliomyelitis","text":"Phenotype: Acute poliomyelitis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0187
N cases: 369
N controls: 375157"}
{"pvalue":0.688,"sign":-1,"group":"AB1: Infectious diseases","label":"Protozoal diseases","text":"Phenotype: Protozoal diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.688
N cases: 663
N controls: 376614"}
{"pvalue":0.669,"sign":-1,"group":"AB1: Infectious diseases","label":"Respiratory tuberculosis, bacteriologically and histologically confirmed","text":"Phenotype: Respiratory tuberculosis, bacteriologically and histologically confirmed
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.669
N cases: 543
N controls: 374845"}
{"pvalue":0.8,"sign":-1,"group":"AB1: Infectious diseases","label":"Respiratory tuberculosis, not confirmed bacteriologically or histologically","text":"Phenotype: Respiratory tuberculosis, not confirmed bacteriologically or histologically
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.8
N cases: 1329
N controls: 374845"}
{"pvalue":0.565,"sign":1,"group":"AB1: Infectious diseases","label":"Rubella [German measles]","text":"Phenotype: Rubella [German measles]
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.565
N cases: 955
N controls: 362997"}
{"pvalue":0.597,"sign":-1,"group":"AB1: Infectious diseases","label":"Other salmonella infections","text":"Phenotype: Other salmonella infections
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.597
N cases: 1046
N controls: 336396"}
{"pvalue":0.248,"sign":-1,"group":"AB1: Infectious diseases","label":"Scabies","text":"Phenotype: Scabies
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.248
N cases: 1105
N controls: 375759"}
{"pvalue":0.36,"sign":-1,"group":"AB1: Infectious diseases","label":"Scarlet fever","text":"Phenotype: Scarlet fever
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.36
N cases: 186
N controls: 332343"}
{"pvalue":0.745,"sign":1,"group":"AB1: Infectious diseases","label":"Sequelae of other and unspecified infectious and parasitic diseases","text":"Phenotype: Sequelae of other and unspecified infectious and parasitic diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.745
N cases: 1624
N controls: 374884"}
{"pvalue":0.486,"sign":-1,"group":"AB1: Infectious diseases","label":"Sequelae of poliomyelitis","text":"Phenotype: Sequelae of poliomyelitis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.486
N cases: 204
N controls: 374884"}
{"pvalue":0.548,"sign":1,"group":"AB1: Infectious diseases","label":"Sequelae of tuberculosis","text":"Phenotype: Sequelae of tuberculosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.548
N cases: 569
N controls: 374884"}
{"pvalue":0.664,"sign":1,"group":"AB1: Infectious diseases","label":"Sequelae of infectious and parasitic diseases","text":"Phenotype: Sequelae of infectious and parasitic diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.664
N cases: 2393
N controls: 374884"}
{"pvalue":0.294,"sign":-1,"group":"AB1: Infectious diseases","label":"Infections with a predominantly sexual mode of transmission","text":"Phenotype: Infections with a predominantly sexual mode of transmission
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.294
N cases: 10937
N controls: 366340"}
{"pvalue":0.0285,"sign":-1,"group":"AB1: Infectious diseases","label":"Other predominantly sexually transmitted diseases, not elsewhere classified","text":"Phenotype: Other predominantly sexually transmitted diseases, not elsewhere classified
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0285
N cases: 5753
N controls: 366340"}
{"pvalue":0.302,"sign":-1,"group":"AB1: Infectious diseases","label":"Shigellosis","text":"Phenotype: Shigellosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.302
N cases: 83
N controls: 336396"}
{"pvalue":0.75,"sign":-1,"group":"AB1: Infectious diseases","label":"Streptococcal septicaemia","text":"Phenotype: Streptococcal septicaemia
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.75
N cases: 2348
N controls: 332343"}
{"pvalue":0.866,"sign":-1,"group":"AB1: Infectious diseases","label":"Streptococcus and staphylococcus as the cause of diseases classified to other chapters","text":"Phenotype: Streptococcus and staphylococcus as the cause of diseases classified to other chapters
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.866
N cases: 151
N controls: 374686"}
{"pvalue":0.552,"sign":1,"group":"AB1: Infectious diseases","label":"Syphilis","text":"Phenotype: Syphilis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.552
N cases: 662
N controls: 366340"}
{"pvalue":0.296,"sign":-1,"group":"AB1: Infectious diseases","label":"Tick-borne viral encephalitis","text":"Phenotype: Tick-borne viral encephalitis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.296
N cases: 82
N controls: 375157"}
{"pvalue":0.877,"sign":1,"group":"AB1: Infectious diseases","label":"Toxoplasmosis","text":"Phenotype: Toxoplasmosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.877
N cases: 154
N controls: 376614"}
{"pvalue":0.33,"sign":-1,"group":"AB1: Infectious diseases","label":"Trichomoniasis","text":"Phenotype: Trichomoniasis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.33
N cases: 219
N controls: 366340"}
{"pvalue":0.712,"sign":-1,"group":"AB1: Infectious diseases","label":"Tuberculosis","text":"Phenotype: Tuberculosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.712
N cases: 2432
N controls: 374845"}
{"pvalue":0.603,"sign":1,"group":"AB1: Infectious diseases","label":"Tuberculosis of other organs","text":"Phenotype: Tuberculosis of other organs
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.603
N cases: 676
N controls: 374845"}
{"pvalue":0.829,"sign":-1,"group":"AB1: Infectious diseases","label":"Tularaemia","text":"Phenotype: Tularaemia
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.829
N cases: 298
N controls: 376827"}
{"pvalue":0.346,"sign":1,"group":"AB1: Infectious diseases","label":"Typhoid and paratyphoid fevers","text":"Phenotype: Typhoid and paratyphoid fevers
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.346
N cases: 114
N controls: 336396"}
{"pvalue":0.691,"sign":-1,"group":"AB1: Infectious diseases","label":"Varicella [chickenpox]","text":"Phenotype: Varicella [chickenpox]
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.691
N cases: 1289
N controls: 362997"}
{"pvalue":0.862,"sign":1,"group":"AB1: Infectious diseases","label":"Viral conjunctivitis","text":"Phenotype: Viral conjunctivitis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.862
N cases: 556
N controls: 367472"}
{"pvalue":0.0153,"sign":-1,"group":"AB1: Infectious diseases","label":"Viral infections of the central nervous system","text":"Phenotype: Viral infections of the central nervous system
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0153
N cases: 2120
N controls: 375157"}
{"pvalue":0.0338,"sign":-1,"group":"AB1: Infectious diseases","label":"Viral encephalitis, not elsewhere classified/unspecified","text":"Phenotype: Viral encephalitis, not elsewhere classified/unspecified
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0338
N cases: 536
N controls: 375157"}
{"pvalue":0.493,"sign":-1,"group":"AB1: Infectious diseases","label":"Viral haemorrhagic fevers, not elsewhere classified/unspecified","text":"Phenotype: Viral haemorrhagic fevers, not elsewhere classified/unspecified
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.493
N cases: 2166
N controls: 374565"}
{"pvalue":0.975,"sign":-1,"group":"AB1: Infectious diseases","label":"Viral hepatitis","text":"Phenotype: Viral hepatitis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.975
N cases: 2143
N controls: 375134"}
{"pvalue":0.995,"sign":1,"group":"AB1: Infectious diseases","label":"Viral agents as the cause of diseases classified to other chapters","text":"Phenotype: Viral agents as the cause of diseases classified to other chapters
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.995
N cases: 535
N controls: 374686"}
{"pvalue":0.128,"sign":-1,"group":"AB1: Infectious diseases","label":"Viral meningitis","text":"Phenotype: Viral meningitis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.128
N cases: 1012
N controls: 375157"}
{"pvalue":0.431,"sign":-1,"group":"AB1: Infectious diseases","label":"Other viral diseases, not elsewhere classified","text":"Phenotype: Other viral diseases, not elsewhere classified
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.431
N cases: 5864
N controls: 367472"}
{"pvalue":0.0564,"sign":-1,"group":"AB1: Infectious diseases","label":"Viral and other specified intestinal infections","text":"Phenotype: Viral and other specified intestinal infections
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0564
N cases: 7613
N controls: 336396"}
{"pvalue":0.161,"sign":1,"group":"AB1: Infectious diseases","label":"Viral infections characterized by skin and mucous membrane lesions","text":"Phenotype: Viral infections characterized by skin and mucous membrane lesions
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.161
N cases: 14280
N controls: 362997"}
{"pvalue":0.716,"sign":-1,"group":"AB1: Infectious diseases","label":"Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified","text":"Phenotype: Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.716
N cases: 1009
N controls: 362997"}
{"pvalue":0.278,"sign":1,"group":"AB1: Infectious diseases","label":"Viral warts","text":"Phenotype: Viral warts
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.278
N cases: 2940
N controls: 362997"}
{"pvalue":0.627,"sign":-1,"group":"AB1: Infectious diseases","label":"Viral infections of central nervous system, not elsewhere classified/unspecified","text":"Phenotype: Viral infections of central nervous system, not elsewhere classified/unspecified
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.627
N cases: 310
N controls: 375157"}
{"pvalue":0.144,"sign":1,"group":"AB1: Infectious diseases","label":"Whooping cough","text":"Phenotype: Whooping cough
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.144
N cases: 147
N controls: 332343"}
{"pvalue":0.896,"sign":1,"group":"AB1: Infectious diseases","label":"Certain zoonotic bacterial diseases","text":"Phenotype: Certain zoonotic bacterial diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.896
N cases: 450
N controls: 376827"}
{"pvalue":0.427,"sign":1,"group":"AB1: Infectious diseases","label":"Zoster [herpes zoster]","text":"Phenotype: Zoster [herpes zoster]
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.427
N cases: 4973
N controls: 362997"}
{"pvalue":0.0186,"sign":1,"group":"K11: Digestive system diseases","label":"Hernia of abdominal wall","text":"Phenotype: Hernia of abdominal wall
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0186
N cases: 15338
N controls: 361939"}
{"pvalue":0.484,"sign":1,"group":"K11: Digestive system diseases","label":"Hernia of abdominal wall, postoperative","text":"Phenotype: Hernia of abdominal wall, postoperative
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.484
N cases: 5775
N controls: 210314"}
{"pvalue":0.344,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute drug-induced interstitial lung disorder","text":"Phenotype: Acute drug-induced interstitial lung disorder
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.344
N cases: 192
N controls: 377085"}
{"pvalue":0.755,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Alcohol withdrawal state with delirium ","text":"Phenotype: Alcohol withdrawal state with delirium
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.755
N cases: 2058
N controls: 375219"}
{"pvalue":0.373,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Allergic contact dermatitis due to drugs in contact with skin","text":"Phenotype: Allergic contact dermatitis due to drugs in contact with skin
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.373
N cases: 574
N controls: 376703"}
{"pvalue":0.625,"sign":-1,"group":"K11: Digestive system diseases","label":"Acute appendicitis, with complications","text":"Phenotype: Acute appendicitis, with complications
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.625
N cases: 6747
N controls: 346283"}
{"pvalue":0.0172,"sign":1,"group":"K11: Digestive system diseases","label":"Acute appendicitis, no complications","text":"Phenotype: Acute appendicitis, no complications
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0172
N cases: 21998
N controls: 346283"}
{"pvalue":0.279,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Alcohol use disorder, ICD-based","text":"Phenotype: Alcohol use disorder, ICD-based
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.279
N cases: 15715
N controls: 361562"}
{"pvalue":0.69,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Autoimmune hyperthyroidism","text":"Phenotype: Autoimmune hyperthyroidism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.69
N cases: 1828
N controls: 279855"}
{"pvalue":0.745,"sign":1,"group":"AB1: Infectious diseases","label":"Other specified/unspecified bacterial intestinal infections","text":"Phenotype: Other specified/unspecified bacterial intestinal infections
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.745
N cases: 1749
N controls: 371656"}
{"pvalue":0.122,"sign":1,"group":"AB1: Infectious diseases","label":"Campylobacter enteritis","text":"Phenotype: Campylobacter enteritis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.122
N cases: 701
N controls: 371656"}
{"pvalue":0.883,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Adrenal gland","text":"Phenotype: Benign neoplasm: Adrenal gland
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.883
N cases: 1790
N controls: 375487"}
{"pvalue":0.885,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Anus and anal canal","text":"Phenotype: Benign neoplasm: Anus and anal canal
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.885
N cases: 726
N controls: 376551"}
{"pvalue":0.641,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Appendix","text":"Phenotype: Benign neoplasm: Appendix
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.641
N cases: 251
N controls: 377026"}
{"pvalue":0.55,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Ascending colon","text":"Phenotype: Benign neoplasm: Ascending colon
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.55
N cases: 3177
N controls: 374100"}
{"pvalue":0.705,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Bladder","text":"Phenotype: Benign neoplasm: Bladder
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.705
N cases: 239
N controls: 377038"}
{"pvalue":0.572,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of bone and articular cartilage","text":"Phenotype: Benign neoplasm of bone and articular cartilage
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.572
N cases: 2335
N controls: 374942"}
{"pvalue":0.71,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Bone and articular cartilage, unspecified","text":"Phenotype: Benign neoplasm: Bone and articular cartilage, unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.71
N cases: 192
N controls: 377085"}
{"pvalue":0.496,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Long bones of lower limb","text":"Phenotype: Benign neoplasm: Long bones of lower limb
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.496
N cases: 837
N controls: 376440"}
{"pvalue":0.246,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Lower jaw bone","text":"Phenotype: Benign neoplasm: Lower jaw bone
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.246
N cases: 114
N controls: 377163"}
{"pvalue":0.0275,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Scapula and long bones of upper limb","text":"Phenotype: Benign neoplasm: Scapula and long bones of upper limb
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.0275
N cases: 254
N controls: 377023"}
{"pvalue":0.662,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Short bones of lower limb","text":"Phenotype: Benign neoplasm: Short bones of lower limb
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.662
N cases: 262
N controls: 377015"}
{"pvalue":0.372,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Short bones of upper limb","text":"Phenotype: Benign neoplasm: Short bones of upper limb
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.372
N cases: 397
N controls: 376880"}
{"pvalue":0.0764,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Bones of skull and face","text":"Phenotype: Benign neoplasm: Bones of skull and face
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.0764
N cases: 234
N controls: 377043"}
{"pvalue":0.155,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of brain and other parts of central nervous system","text":"Phenotype: Benign neoplasm of brain and other parts of central nervous system
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.155
N cases: 1751
N controls: 375526"}
{"pvalue":0.767,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Brain, infratentorial","text":"Phenotype: Benign neoplasm: Brain, infratentorial
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.767
N cases: 145
N controls: 377132"}
{"pvalue":0.828,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Brain, unspecified","text":"Phenotype: Benign neoplasm: Brain, unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.828
N cases: 157
N controls: 377120"}
{"pvalue":0.3,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Brain, supratentorial","text":"Phenotype: Benign neoplasm: Brain, supratentorial
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.3
N cases: 419
N controls: 376858"}
{"pvalue":0.884,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of breast","text":"Phenotype: Benign neoplasm of breast
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.884
N cases: 3574
N controls: 207296"}
{"pvalue":0.127,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Bronchus and lung","text":"Phenotype: Benign neoplasm: Bronchus and lung
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.127
N cases: 331
N controls: 376946"}
{"pvalue":0.247,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Caecum","text":"Phenotype: Benign neoplasm: Caecum
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.247
N cases: 2463
N controls: 374814"}
{"pvalue":0.226,"sign":-1,"group":"CD2: Neoplasms","label":"Other benign neoplasm of uterus: Cervix uteri","text":"Phenotype: Other benign neoplasm of uterus: Cervix uteri
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.226
N cases: 146
N controls: 210724"}
{"pvalue":0.61,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Choroid","text":"Phenotype: Benign neoplasm: Choroid
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.61
N cases: 1324
N controls: 375953"}
{"pvalue":0.867,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Central nervous system, other parts/unspecified","text":"Phenotype: Benign neoplasm: Central nervous system, other parts/unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.867
N cases: 90
N controls: 377187"}
{"pvalue":0.18,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Colon","text":"Phenotype: Benign neoplasm: Colon
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.18
N cases: 16445
N controls: 360832"}
{"pvalue":0.75,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Colon, unspecified","text":"Phenotype: Benign neoplasm: Colon, unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.75
N cases: 7013
N controls: 370264"}
{"pvalue":0.554,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of colon, rectum, anus and anal canal","text":"Phenotype: Benign neoplasm of colon, rectum, anus and anal canal
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.554
N cases: 20336
N controls: 356941"}
{"pvalue":0.236,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Conjunctiva","text":"Phenotype: Benign neoplasm: Conjunctiva
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.236
N cases: 824
N controls: 376453"}
{"pvalue":0.638,"sign":-1,"group":"CD2: Neoplasms","label":"Other benign neoplasms of connective and other soft tissue","text":"Phenotype: Other benign neoplasms of connective and other soft tissue
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.638
N cases: 2857
N controls: 374420"}
{"pvalue":0.865,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Connective and other soft tissue of thorax","text":"Phenotype: Benign neoplasm: Connective and other soft tissue of thorax
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.865
N cases: 115
N controls: 377162"}
{"pvalue":0.62,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Connective and other soft tissue of trunk, unspecified","text":"Phenotype: Benign neoplasm: Connective and other soft tissue of trunk, unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.62
N cases: 163
N controls: 377114"}
{"pvalue":0.641,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder","text":"Phenotype: Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.641
N cases: 1156
N controls: 376121"}
{"pvalue":0.736,"sign":1,"group":"CD2: Neoplasms","label":"Other benign neoplasm of uterus: Corpus uteri","text":"Phenotype: Other benign neoplasm of uterus: Corpus uteri
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.736
N cases: 177
N controls: 210693"}
{"pvalue":0.328,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Cranial nerves","text":"Phenotype: Benign neoplasm: Cranial nerves
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.328
N cases: 710
N controls: 376567"}
{"pvalue":0.206,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Descending colon","text":"Phenotype: Benign neoplasm: Descending colon
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.206
N cases: 1571
N controls: 375706"}
{"pvalue":0.692,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Ill-defined sites within the digestive system","text":"Phenotype: Benign neoplasm: Ill-defined sites within the digestive system
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.692
N cases: 146
N controls: 377131"}
{"pvalue":0.983,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Duodenum","text":"Phenotype: Benign neoplasm: Duodenum
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.983
N cases: 627
N controls: 376650"}
{"pvalue":0.0556,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Middle ear, nasal cavity and accessory sinuses","text":"Phenotype: Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.0556
N cases: 1046
N controls: 376231"}
{"pvalue":0.341,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of middle ear and respiratory system","text":"Phenotype: Benign neoplasm of middle ear and respiratory system
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.341
N cases: 2271
N controls: 375006"}
{"pvalue":0.336,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Endocrine gland, other/unspecified","text":"Phenotype: Benign neoplasm: Endocrine gland, other/unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.336
N cases: 93
N controls: 377184"}
{"pvalue":0.243,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of other and unspecified endocrine glands","text":"Phenotype: Benign neoplasm of other and unspecified endocrine glands
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.243
N cases: 3544
N controls: 373733"}
{"pvalue":0.508,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Endocrine pancreas","text":"Phenotype: Benign neoplasm: Endocrine pancreas
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.508
N cases: 135
N controls: 377142"}
{"pvalue":0.384,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Epididymis","text":"Phenotype: Benign neoplasm: Epididymis
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.384
N cases: 85
N controls: 166322"}
{"pvalue":0.527,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of eye and adnexa","text":"Phenotype: Benign neoplasm of eye and adnexa
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.527
N cases: 2555
N controls: 374722"}
{"pvalue":0.789,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of other and unspecified female genital organs","text":"Phenotype: Benign neoplasm of other and unspecified female genital organs
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.789
N cases: 1151
N controls: 209719"}
{"pvalue":0.274,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Floor of mouth","text":"Phenotype: Benign neoplasm: Floor of mouth
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.274
N cases: 91
N controls: 377186"}
{"pvalue":0.0657,"sign":1,"group":"CD2: Neoplasms","label":"Haemangioma and lymphangioma, any site","text":"Phenotype: Haemangioma and lymphangioma, any site
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.0657
N cases: 2488
N controls: 374789"}
{"pvalue":0.00651,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Heart","text":"Phenotype: Benign neoplasm: Heart
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.00651
N cases: 81
N controls: 377196"}
{"pvalue":0.039,"sign":1,"group":"CD2: Neoplasms","label":"Haemangioma, any site","text":"Phenotype: Haemangioma, any site
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.039
N cases: 2292
N controls: 374985"}
{"pvalue":0.319,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Hypopharynx","text":"Phenotype: Benign neoplasm: Hypopharynx
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.319
N cases: 117
N controls: 377160"}
{"pvalue":0.157,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of other and unspecified intrathoracic organs","text":"Phenotype: Benign neoplasm of other and unspecified intrathoracic organs
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.157
N cases: 280
N controls: 376997"}
{"pvalue":0.654,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Kidney","text":"Phenotype: Benign neoplasm: Kidney
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.654
N cases: 801
N controls: 376476"}
{"pvalue":0.337,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Larynx","text":"Phenotype: Benign neoplasm: Larynx
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.337
N cases: 887
N controls: 376390"}
{"pvalue":0.745,"sign":-1,"group":"CD2: Neoplasms","label":"Leiomyoma of uterus","text":"Phenotype: Leiomyoma of uterus
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.745
N cases: 31661
N controls: 179209"}
{"pvalue":0.187,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Lip","text":"Phenotype: Benign neoplasm: Lip
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.187
N cases: 589
N controls: 376688"}
{"pvalue":0.815,"sign":-1,"group":"CD2: Neoplasms","label":"Benign lipomatous neoplasm","text":"Phenotype: Benign lipomatous neoplasm
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.815
N cases: 9431
N controls: 367846"}
{"pvalue":0.255,"sign":-1,"group":"CD2: Neoplasms","label":"Benign lipomatous neoplasm of other sites/unspecified","text":"Phenotype: Benign lipomatous neoplasm of other sites/unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.255
N cases: 2576
N controls: 374701"}
{"pvalue":0.772,"sign":1,"group":"CD2: Neoplasms","label":"Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck","text":"Phenotype: Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.772
N cases: 1745
N controls: 375532"}
{"pvalue":0.613,"sign":-1,"group":"CD2: Neoplasms","label":"Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs","text":"Phenotype: Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.613
N cases: 2159
N controls: 375118"}
{"pvalue":0.859,"sign":-1,"group":"CD2: Neoplasms","label":"Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites","text":"Phenotype: Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.859
N cases: 183
N controls: 377094"}
{"pvalue":0.784,"sign":-1,"group":"CD2: Neoplasms","label":"Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk","text":"Phenotype: Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.784
N cases: 3754
N controls: 373523"}
{"pvalue":0.952,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Liver/bile ducts","text":"Phenotype: Benign neoplasm: Liver/bile ducts
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.952
N cases: 551
N controls: 376726"}
{"pvalue":0.875,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Liver","text":"Phenotype: Benign neoplasm: Liver
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.875
N cases: 491
N controls: 376786"}
{"pvalue":0.644,"sign":-1,"group":"CD2: Neoplasms","label":"Lymphangioma, anys site","text":"Phenotype: Lymphangioma, anys site
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.644
N cases: 210
N controls: 377067"}
{"pvalue":0.285,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of male genital organs","text":"Phenotype: Benign neoplasm of male genital organs
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.285
N cases: 540
N controls: 165867"}
{"pvalue":0.701,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Mediastinum","text":"Phenotype: Benign neoplasm: Mediastinum
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.701
N cases: 86
N controls: 377191"}
{"pvalue":0.283,"sign":-1,"group":"CD2: Neoplasms","label":"Melanocytic naevi of ear and external auricular canal","text":"Phenotype: Melanocytic naevi of ear and external auricular canal
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.283
N cases: 143
N controls: 377134"}
{"pvalue":0.765,"sign":1,"group":"CD2: Neoplasms","label":"Melanocytic naevi of eyelid, including canthus","text":"Phenotype: Melanocytic naevi of eyelid, including canthus
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.765
N cases: 223
N controls: 377054"}
{"pvalue":0.922,"sign":1,"group":"CD2: Neoplasms","label":"Melanocytic naevi of other and unspecified parts of face","text":"Phenotype: Melanocytic naevi of other and unspecified parts of face
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.922
N cases: 1574
N controls: 375703"}
{"pvalue":0.666,"sign":1,"group":"CD2: Neoplasms","label":"Melanocytic naevi","text":"Phenotype: Melanocytic naevi
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.666
N cases: 8900
N controls: 368377"}
{"pvalue":0.701,"sign":-1,"group":"CD2: Neoplasms","label":"Melanocytic naevi of lip","text":"Phenotype: Melanocytic naevi of lip
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.701
N cases: 224
N controls: 377053"}
{"pvalue":0.859,"sign":1,"group":"CD2: Neoplasms","label":"Melanocytic naevi of lower limb, including hip","text":"Phenotype: Melanocytic naevi of lower limb, including hip
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.859
N cases: 1108
N controls: 376169"}
{"pvalue":0.316,"sign":-1,"group":"CD2: Neoplasms","label":"Melanocytic naevi, other sites/unspecified","text":"Phenotype: Melanocytic naevi, other sites/unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.316
N cases: 1992
N controls: 375285"}
{"pvalue":0.185,"sign":1,"group":"CD2: Neoplasms","label":"Melanocytic naevi of scalp and neck","text":"Phenotype: Melanocytic naevi of scalp and neck
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.185
N cases: 598
N controls: 376679"}
{"pvalue":0.788,"sign":-1,"group":"CD2: Neoplasms","label":"Melanocytic naevi of trunk","text":"Phenotype: Melanocytic naevi of trunk
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.788
N cases: 3295
N controls: 373982"}
{"pvalue":0.555,"sign":-1,"group":"CD2: Neoplasms","label":"Melanocytic naevi of upper limb, including shoulder","text":"Phenotype: Melanocytic naevi of upper limb, including shoulder
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.555
N cases: 573
N controls: 376704"}
{"pvalue":0.376,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Cerebral meninges","text":"Phenotype: Benign neoplasm: Cerebral meninges
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.376
N cases: 2382
N controls: 374895"}
{"pvalue":0.412,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of meninges","text":"Phenotype: Benign neoplasm of meninges
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.412
N cases: 2655
N controls: 374622"}
{"pvalue":0.521,"sign":1,"group":"CD2: Neoplasms","label":"Beningn neoplasm: Meninges, unspecified","text":"Phenotype: Beningn neoplasm: Meninges, unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.521
N cases: 400
N controls: 376877"}
{"pvalue":0.856,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Spinal meninges","text":"Phenotype: Benign neoplasm: Spinal meninges
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.856
N cases: 242
N controls: 377035"}
{"pvalue":0.78,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Other and unspecified parts of mouth","text":"Phenotype: Benign neoplasm: Other and unspecified parts of mouth
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.78
N cases: 920
N controls: 376357"}
{"pvalue":0.682,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of mouth and pharynx","text":"Phenotype: Benign neoplasm of mouth and pharynx
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.682
N cases: 3216
N controls: 374061"}
{"pvalue":0.279,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Nasopharynx","text":"Phenotype: Benign neoplasm: Nasopharynx
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.279
N cases: 224
N controls: 377053"}
{"pvalue":0.359,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Other/unspecified site","text":"Phenotype: Benign neoplasm: Other/unspecified site
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.359
N cases: 424
N controls: 376853"}
{"pvalue":0.682,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Oesophagus","text":"Phenotype: Benign neoplasm: Oesophagus
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.682
N cases: 295
N controls: 376982"}
{"pvalue":0.685,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Orbit, unspecified","text":"Phenotype: Benign neoplasm: Orbit, unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.685
N cases: 150
N controls: 377127"}
{"pvalue":0.623,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Other parts of oropharynx","text":"Phenotype: Benign neoplasm: Other parts of oropharynx
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.623
N cases: 225
N controls: 377052"}
{"pvalue":0.0579,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of other and ill-defined parts of digestive system","text":"Phenotype: Benign neoplasm of other and ill-defined parts of digestive system
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.0579
N cases: 5062
N controls: 372215"}
{"pvalue":0.464,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of other and unspecified sites","text":"Phenotype: Benign neoplasm of other and unspecified sites
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.464
N cases: 866
N controls: 376411"}
{"pvalue":0.888,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of ovary","text":"Phenotype: Benign neoplasm of ovary
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.888
N cases: 5308
N controls: 205562"}
{"pvalue":0.456,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Pancreas","text":"Phenotype: Benign neoplasm: Pancreas
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.456
N cases: 549
N controls: 376728"}
{"pvalue":0.0391,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Parathyroid gland","text":"Phenotype: Benign neoplasm: Parathyroid gland
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.0391
N cases: 274
N controls: 377003"}
{"pvalue":0.535,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Parotid gland","text":"Phenotype: Benign neoplasm: Parotid gland
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.535
N cases: 2144
N controls: 375133"}
{"pvalue":0.375,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Pelvic bones, sacrum and coccyx","text":"Phenotype: Benign neoplasm: Pelvic bones, sacrum and coccyx
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.375
N cases: 80
N controls: 377197"}
{"pvalue":0.84,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Peripheral nerves and autonomic nervous system","text":"Phenotype: Benign neoplasm: Peripheral nerves and autonomic nervous system
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.84
N cases: 386
N controls: 376891"}
{"pvalue":0.991,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Pharynx, unspecified","text":"Phenotype: Benign neoplasm: Pharynx, unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.991
N cases: 182
N controls: 377095"}
{"pvalue":0.213,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Pituitary gland, craniopharyngeal duct","text":"Phenotype: Benign neoplasm: Pituitary gland, craniopharyngeal duct
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.213
N cases: 1402
N controls: 375875"}
{"pvalue":0.231,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Prostate","text":"Phenotype: Benign neoplasm: Prostate
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.231
N cases: 171
N controls: 166236"}
{"pvalue":0.403,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Rectosigmoid junction","text":"Phenotype: Benign neoplasm: Rectosigmoid junction
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.403
N cases: 982
N controls: 376295"}
{"pvalue":0.763,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Rectum/anal canal icd-9","text":"Phenotype: Benign neoplasm: Rectum/anal canal icd-9
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.763
N cases: 290
N controls: 376987"}
{"pvalue":0.647,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Rectum, anus and anal canal","text":"Phenotype: Benign neoplasm: Rectum, anus and anal canal
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.647
N cases: 5613
N controls: 371664"}
{"pvalue":0.704,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Rectum","text":"Phenotype: Benign neoplasm: Rectum
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.704
N cases: 4776
N controls: 372501"}
{"pvalue":0.885,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Retina","text":"Phenotype: Benign neoplasm: Retina
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.885
N cases: 125
N controls: 377152"}
{"pvalue":0.697,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of soft tissue of retroperitoneum and peritoneum","text":"Phenotype: Benign neoplasm of soft tissue of retroperitoneum and peritoneum
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.697
N cases: 138
N controls: 377139"}
{"pvalue":0.375,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of major salivary glands","text":"Phenotype: Benign neoplasm of major salivary glands
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.375
N cases: 2785
N controls: 374492"}
{"pvalue":0.253,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: salivary glands, exclude unknown (D119)","text":"Phenotype: Benign neoplasm: salivary glands, exclude unknown (D119)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.253
N cases: 2415
N controls: 374862"}
{"pvalue":0.492,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: other/unspecified salivary gland","text":"Phenotype: Benign neoplasm: other/unspecified salivary gland
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.492
N cases: 756
N controls: 376521"}
{"pvalue":0.349,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Scrotum","text":"Phenotype: Benign neoplasm: Scrotum
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.349
N cases: 99
N controls: 166308"}
{"pvalue":0.0461,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Sigmoid colon","text":"Phenotype: Benign neoplasm: Sigmoid colon
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.0461
N cases: 4876
N controls: 372401"}
{"pvalue":0.572,"sign":-1,"group":"CD2: Neoplasms","label":"Other benign neoplasms of skin","text":"Phenotype: Other benign neoplasms of skin
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.572
N cases: 12341
N controls: 364936"}
{"pvalue":0.936,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Small intestine","text":"Phenotype: Benign neoplasm: Small intestine
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.936
N cases: 1031
N controls: 376246"}
{"pvalue":0.493,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Other and unspecified parts of small intestine","text":"Phenotype: Benign neoplasm: Other and unspecified parts of small intestine
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.493
N cases: 427
N controls: 376850"}
{"pvalue":0.501,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Spinal cord","text":"Phenotype: Benign neoplasm: Spinal cord
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.501
N cases: 355
N controls: 376922"}
{"pvalue":0.0179,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Stomach","text":"Phenotype: Benign neoplasm: Stomach
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.0179
N cases: 2658
N controls: 374619"}
{"pvalue":0.0793,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Testis","text":"Phenotype: Benign neoplasm: Testis
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.0793
N cases: 108
N controls: 166299"}
{"pvalue":0.769,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm of thyroid gland","text":"Phenotype: Benign neoplasm of thyroid gland
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.769
N cases: 875
N controls: 376402"}
{"pvalue":0.708,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Tongue","text":"Phenotype: Benign neoplasm: Tongue
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.708
N cases: 720
N controls: 376557"}
{"pvalue":0.205,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Tonsil","text":"Phenotype: Benign neoplasm: Tonsil
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.205
N cases: 281
N controls: 376996"}
{"pvalue":0.708,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Transverse colon","text":"Phenotype: Benign neoplasm: Transverse colon
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.708
N cases: 2404
N controls: 374873"}
{"pvalue":0.302,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm of urinary organs","text":"Phenotype: Benign neoplasm of urinary organs
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.302
N cases: 1165
N controls: 376112"}
{"pvalue":0.0537,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Uterine tubes and ligaments","text":"Phenotype: Benign neoplasm: Uterine tubes and ligaments
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.0537
N cases: 163
N controls: 210707"}
{"pvalue":0.195,"sign":-1,"group":"CD2: Neoplasms","label":"Other benign neoplasm of uterus: Other parts/unspecified","text":"Phenotype: Other benign neoplasm of uterus: Other parts/unspecified
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.195
N cases: 1160
N controls: 209710"}
{"pvalue":0.236,"sign":-1,"group":"CD2: Neoplasms","label":"Other benign neoplasms of uterus","text":"Phenotype: Other benign neoplasms of uterus
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.236
N cases: 1477
N controls: 209393"}
{"pvalue":0.701,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Vulva","text":"Phenotype: Benign neoplasm: Vulva
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.701
N cases: 550
N controls: 210320"}
{"pvalue":0.423,"sign":-1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Vagina","text":"Phenotype: Benign neoplasm: Vagina
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.423
N cases: 325
N controls: 210545"}
{"pvalue":0.451,"sign":1,"group":"CD2: Neoplasms","label":"Benign neoplasm: Eye, unspecified (controls excluding all cancers)","text":"Phenotype: Benign neoplasm: Eye, unspecified (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.451
N cases: 113
N controls: 299881"}
{"pvalue":0.954,"sign":1,"group":"CD2: Neoplasms","label":"Follicular lymphoma (controls excluding all cancers)","text":"Phenotype: Follicular lymphoma (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.954
N cases: 1081
N controls: 299952"}
{"pvalue":0.962,"sign":1,"group":"CD2: Neoplasms","label":"Follicular lymphoma","text":"Phenotype: Follicular lymphoma
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.962
N cases: 1081
N controls: 376196"}
{"pvalue":0.23,"sign":1,"group":"CD2: Neoplasms","label":"Hodgkin lymphoma (controls excluding all cancers)","text":"Phenotype: Hodgkin lymphoma (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.23
N cases: 780
N controls: 299952"}
{"pvalue":0.25,"sign":1,"group":"CD2: Neoplasms","label":"Hodgkin lymphoma","text":"Phenotype: Hodgkin lymphoma
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.25
N cases: 780
N controls: 376497"}
{"pvalue":0.556,"sign":-1,"group":"CD2: Neoplasms","label":"Malignant immunoproliferative diseases (controls excluding all cancers)","text":"Phenotype: Malignant immunoproliferative diseases (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.556
N cases: 223
N controls: 299952"}
{"pvalue":0.0328,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ, bladder (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ, bladder (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.0328
N cases: 654
N controls: 287130"}
{"pvalue":0.0723,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of breast (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of breast (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.0723
N cases: 278
N controls: 167052"}
{"pvalue":0.882,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of breast, intraductal (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of breast, intraductal (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.882
N cases: 2219
N controls: 167070"}
{"pvalue":0.447,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of breast, lobular (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of breast, lobular (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.447
N cases: 167
N controls: 167176"}
{"pvalue":0.341,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of cervix uteri (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of cervix uteri (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.341
N cases: 2236
N controls: 165401"}
{"pvalue":0.477,"sign":-1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of colon (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of colon (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.477
N cases: 124
N controls: 287092"}
{"pvalue":0.528,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of endometrium (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of endometrium (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.528
N cases: 106
N controls: 167161"}
{"pvalue":0.583,"sign":-1,"group":"CD2: Neoplasms","label":"Melanoma in situ (controls excluding all cancers)","text":"Phenotype: Melanoma in situ (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.583
N cases: 887
N controls: 286876"}
{"pvalue":0.309,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of prostate (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of prostate (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.309
N cases: 141
N controls: 119882"}
{"pvalue":0.0641,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of rectum (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of rectum (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.0641
N cases: 81
N controls: 287104"}
{"pvalue":0.516,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of skin (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of skin (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.516
N cases: 1911
N controls: 286158"}
{"pvalue":0.13,"sign":1,"group":"CD2: Neoplasms","label":"Carcinoma in situ of vulva (controls excluding all cancers)","text":"Phenotype: Carcinoma in situ of vulva (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.13
N cases: 155
N controls: 167097"}
{"pvalue":0.78,"sign":1,"group":"CD2: Neoplasms","label":"Leukaemia of unspecified cell type (controls excluding all cancers)","text":"Phenotype: Leukaemia of unspecified cell type (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.78
N cases: 220
N controls: 299952"}
{"pvalue":0.813,"sign":1,"group":"CD2: Neoplasms","label":"Leukaemia of unspecified cell type","text":"Phenotype: Leukaemia of unspecified cell type
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.813
N cases: 220
N controls: 377057"}
{"pvalue":0.583,"sign":1,"group":"CD2: Neoplasms","label":"Lymphoid leukaemia (controls excluding all cancers)","text":"Phenotype: Lymphoid leukaemia (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.583
N cases: 1493
N controls: 299952"}
{"pvalue":0.328,"sign":1,"group":"CD2: Neoplasms","label":"Multiple myeloma and malignant plasma cell neoplasms (controls excluding all cancers)","text":"Phenotype: Multiple myeloma and malignant plasma cell neoplasms (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.328
N cases: 1249
N controls: 299952"}
{"pvalue":0.209,"sign":1,"group":"CD2: Neoplasms","label":"Myeloid leukaemia (controls excluding all cancers)","text":"Phenotype: Myeloid leukaemia (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.209
N cases: 674
N controls: 299952"}
{"pvalue":0.221,"sign":1,"group":"CD2: Neoplasms","label":"Myeloid leukaemia","text":"Phenotype: Myeloid leukaemia
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.221
N cases: 674
N controls: 376603"}
{"pvalue":0.293,"sign":-1,"group":"CD2: Neoplasms","label":"Non-follicular lymphoma (controls excluding all cancers)","text":"Phenotype: Non-follicular lymphoma (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.293
N cases: 2602
N controls: 299952"}
{"pvalue":0.238,"sign":-1,"group":"CD2: Neoplasms","label":"Non-follicular lymphoma","text":"Phenotype: Non-follicular lymphoma
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.238
N cases: 2602
N controls: 374675"}
{"pvalue":0.73,"sign":-1,"group":"CD2: Neoplasms","label":"Other and unspecified types of non-Hodgkin lymphoma (controls excluding all cancers)","text":"Phenotype: Other and unspecified types of non-Hodgkin lymphoma (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.73
N cases: 1088
N controls: 299952"}
{"pvalue":0.765,"sign":-1,"group":"CD2: Neoplasms","label":"Other and unspecified types of non-Hodgkin lymphoma","text":"Phenotype: Other and unspecified types of non-Hodgkin lymphoma
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.765
N cases: 1088
N controls: 287137"}
{"pvalue":0.944,"sign":1,"group":"CD2: Neoplasms","label":"Primary_lymphoid and hematopoietic malignant neoplasms (controls excluding all cancers)","text":"Phenotype: Primary_lymphoid and hematopoietic malignant neoplasms (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.944
N cases: 7519
N controls: 299952"}
{"pvalue":0.977,"sign":-1,"group":"CD2: Neoplasms","label":"Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue (controls excluding all cancers)","text":"Phenotype: Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.977
N cases: 248
N controls: 299952"}
{"pvalue":0.365,"sign":-1,"group":"CD2: Neoplasms","label":"Mature T/NK-cell lymphomas (controls excluding all cancers)","text":"Phenotype: Mature T/NK-cell lymphomas (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: -1
p-value: 0.365
N cases: 335
N controls: 299952"}
{"pvalue":0.526,"sign":1,"group":"CD2: Neoplasms","label":"Melanoma of uvea (controls excluding all cancers)","text":"Phenotype: Melanoma of uvea (controls excluding all cancers)
Category: CD2: Neoplasms
rsID: rs2228145-C
Direction: 1
p-value: 0.526
N cases: 242
N controls: 299884"}
{"pvalue":0.585,"sign":-1,"group":"AB1: Infectious diseases","label":"Enterocolitis due to Clostridium difficile","text":"Phenotype: Enterocolitis due to Clostridium difficile
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.585
N cases: 3118
N controls: 371656"}
{"pvalue":0.718,"sign":-1,"group":"AB1: Infectious diseases","label":"Other/unspecified cytomegaloviral diseases","text":"Phenotype: Other/unspecified cytomegaloviral diseases
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.718
N cases: 451
N controls: 376730"}
{"pvalue":0.505,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Acquired haemolytic anaemia","text":"Phenotype: Acquired haemolytic anaemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.505
N cases: 606
N controls: 376439"}
{"pvalue":0.534,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified acquired haemolytic anaemias","text":"Phenotype: Other and unspecified acquired haemolytic anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.534
N cases: 241
N controls: 376439"}
{"pvalue":0.37,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Acquired pure red cell aplasia [erythroblastopenia]","text":"Phenotype: Acquired pure red cell aplasia [erythroblastopenia]
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.37
N cases: 126
N controls: 362319"}
{"pvalue":0.816,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Acute posthaemorrhagic anaemia","text":"Phenotype: Acute posthaemorrhagic anaemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.816
N cases: 976
N controls: 362319"}
{"pvalue":0.171,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Agranulocytosis","text":"Phenotype: Agranulocytosis
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.171
N cases: 3234
N controls: 370400"}
{"pvalue":0.702,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other autoimmune haemolytic anaemias","text":"Phenotype: Other autoimmune haemolytic anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.702
N cases: 280
N controls: 376439"}
{"pvalue":0.163,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Allergic purpura","text":"Phenotype: Allergic purpura
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.163
N cases: 856
N controls: 371504"}
{"pvalue":0.152,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Vitamin B12 deficiency anaemia","text":"Phenotype: Vitamin B12 deficiency anaemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.152
N cases: 3351
N controls: 360528"}
{"pvalue":0.0103,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Folate deficiency anaemia","text":"Phenotype: Folate deficiency anaemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0103
N cases: 178
N controls: 360528"}
{"pvalue":0.274,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Anaemias","text":"Phenotype: Anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.274
N cases: 27371
N controls: 88536"}
{"pvalue":0.157,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Anaemia in chronic diseases classified elsewhere","text":"Phenotype: Anaemia in chronic diseases classified elsewhere
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.157
N cases: 585
N controls: 362319"}
{"pvalue":0.542,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Iron deficiency anaemia secondary to blood loss (chronic)","text":"Phenotype: Iron deficiency anaemia secondary to blood loss (chronic)
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.542
N cases: 4852
N controls: 360528"}
{"pvalue":0.987,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Iron deficiency anaemia","text":"Phenotype: Iron deficiency anaemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.987
N cases: 13689
N controls: 360528"}
{"pvalue":0.714,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified iron deficiency","text":"Phenotype: Other and unspecified iron deficiency
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.714
N cases: 10208
N controls: 360528"}
{"pvalue":0.0641,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified anaemias","text":"Phenotype: Other and unspecified anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0641
N cases: 13600
N controls: 362319"}
{"pvalue":0.358,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified diseases of blood and blood-forming organs","text":"Phenotype: Other and unspecified diseases of blood and blood-forming organs
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.358
N cases: 633
N controls: 370400"}
{"pvalue":0.696,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other diseases of blood and blood-forming organs","text":"Phenotype: Other diseases of blood and blood-forming organs
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.696
N cases: 6877
N controls: 370400"}
{"pvalue":0.0423,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Chronic Coagulation defects","text":"Phenotype: Chronic Coagulation defects
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0423
N cases: 626
N controls: 376651"}
{"pvalue":0.0367,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified coagulation defects","text":"Phenotype: Other and unspecified coagulation defects
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0367
N cases: 1217
N controls: 371504"}
{"pvalue":0.475,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Coagulation defects, purpura and other haemorrhagic conditions","text":"Phenotype: Coagulation defects, purpura and other haemorrhagic conditions
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.475
N cases: 5773
N controls: 371504"}
{"pvalue":0.606,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other coagulation defects","text":"Phenotype: Other coagulation defects
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.606
N cases: 1904
N controls: 371504"}
{"pvalue":0.894,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Combined immunodeficiencies","text":"Phenotype: Combined immunodeficiencies
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.894
N cases: 305
N controls: 371255"}
{"pvalue":0.7,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Defects in the complement system","text":"Phenotype: Defects in the complement system
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.7
N cases: 171
N controls: 371255"}
{"pvalue":0.679,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Common variable immunodeficiency","text":"Phenotype: Common variable immunodeficiency
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.679
N cases: 171
N controls: 371255"}
{"pvalue":0.549,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other or unspecified common variable immunodeficiency","text":"Phenotype: Other or unspecified common variable immunodeficiency
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.549
N cases: 90
N controls: 371255"}
{"pvalue":0.863,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Selective deficiency of immunoglobulin G [IgG] subclasses","text":"Phenotype: Selective deficiency of immunoglobulin G [IgG] subclasses
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.863
N cases: 183
N controls: 371255"}
{"pvalue":0.853,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Selective deficiency of immunoglobulin A [IgA]y","text":"Phenotype: Selective deficiency of immunoglobulin A [IgA]y
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.853
N cases: 112
N controls: 371255"}
{"pvalue":0.484,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Disseminated intravascular coagulation [defibrination syndrome]","text":"Phenotype: Disseminated intravascular coagulation [defibrination syndrome]
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.484
N cases: 83
N controls: 371504"}
{"pvalue":0.42,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Familial erythrocytosis","text":"Phenotype: Familial erythrocytosis
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.42
N cases: 141
N controls: 370400"}
{"pvalue":0.21,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Haemolytic anaemias","text":"Phenotype: Haemolytic anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.21
N cases: 838
N controls: 376439"}
{"pvalue":0.0265,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Haemorrhagic disorder due to circulating anticoagulants","text":"Phenotype: Haemorrhagic disorder due to circulating anticoagulants
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0265
N cases: 267
N controls: 371504"}
{"pvalue":0.82,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified haemorrhagic conditions","text":"Phenotype: Other and unspecified haemorrhagic conditions
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.82
N cases: 404
N controls: 371504"}
{"pvalue":0.917,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other hereditary haemolytic anaemias","text":"Phenotype: Other hereditary haemolytic anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.917
N cases: 140
N controls: 376439"}
{"pvalue":0.564,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Hereditary hypogammaglobulinemia","text":"Phenotype: Hereditary hypogammaglobulinemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.564
N cases: 99
N controls: 371255"}
{"pvalue":0.156,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Hereditary deficiency of other clotting factors","text":"Phenotype: Hereditary deficiency of other clotting factors
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.156
N cases: 216
N controls: 371504"}
{"pvalue":0.163,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Hypersplenism","text":"Phenotype: Hypersplenism
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.163
N cases: 105
N controls: 370400"}
{"pvalue":0.245,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Immunodeficiency with predominantly antibody defects","text":"Phenotype: Immunodeficiency with predominantly antibody defects
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.245
N cases: 711
N controls: 371255"}
{"pvalue":0.0815,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified immunodeficiencies with predominantly antibody defects","text":"Phenotype: Other and unspecified immunodeficiencies with predominantly antibody defects
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0815
N cases: 336
N controls: 371255"}
{"pvalue":0.706,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Immunodeficiencies","text":"Phenotype: Immunodeficiencies
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.706
N cases: 1350
N controls: 375927"}
{"pvalue":0.721,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other or unspecified immunodeficiency","text":"Phenotype: Other or unspecified immunodeficiency
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.721
N cases: 97
N controls: 371255"}
{"pvalue":0.609,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other immunodeficiencies","text":"Phenotype: Other immunodeficiencies
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.609
N cases: 285
N controls: 371255"}
{"pvalue":0.982,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Certain disorders involving the immune mechanism","text":"Phenotype: Certain disorders involving the immune mechanism
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.982
N cases: 6022
N controls: 371255"}
{"pvalue":0.516,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Infarction of spleen","text":"Phenotype: Infarction of spleen
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.516
N cases: 123
N controls: 370400"}
{"pvalue":0.352,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Idiopathic thrombocytopenic purpura","text":"Phenotype: Idiopathic thrombocytopenic purpura
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.352
N cases: 810
N controls: 371504"}
{"pvalue":0.726,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Kela reimbursement Agammaglobulinemia (D80-84)","text":"Phenotype: Kela reimbursement Agammaglobulinemia (D80-84)
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.726
N cases: 202
N controls: 371255"}
{"pvalue":0.648,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Nezelof syndrome","text":"Phenotype: Nezelof syndrome
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.648
N cases: 125
N controls: 371255"}
{"pvalue":0.302,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Nonhereditary hypogammaglobulinemia","text":"Phenotype: Nonhereditary hypogammaglobulinemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.302
N cases: 279
N controls: 371255"}
{"pvalue":0.696,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other nutritional anaemias","text":"Phenotype: Other nutritional anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.696
N cases: 283
N controls: 360528"}
{"pvalue":0.552,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue","text":"Phenotype: Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.552
N cases: 86
N controls: 370400"}
{"pvalue":0.561,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified aplastic anaemias","text":"Phenotype: Other and unspecified aplastic anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.561
N cases: 288
N controls: 362319"}
{"pvalue":0.346,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other diseases of blood and blood-forming organs","text":"Phenotype: Other diseases of blood and blood-forming organs
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.346
N cases: 1892
N controls: 370400"}
{"pvalue":0.612,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other disorders of white blood cells","text":"Phenotype: Other disorders of white blood cells
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.612
N cases: 1483
N controls: 370400"}
{"pvalue":0.74,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other nonthrombocytopenic purpura","text":"Phenotype: Other nonthrombocytopenic purpura
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.74
N cases: 214
N controls: 371504"}
{"pvalue":0.785,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other primary thrombocytopenia","text":"Phenotype: Other primary thrombocytopenia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.785
N cases: 88
N controls: 371504"}
{"pvalue":0.561,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Purpura and other haemorrhagic conditions","text":"Phenotype: Purpura and other haemorrhagic conditions
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.561
N cases: 3900
N controls: 371504"}
{"pvalue":0.824,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Qualitative platelet defects","text":"Phenotype: Qualitative platelet defects
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.824
N cases: 112
N controls: 371504"}
{"pvalue":0.321,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Sarcoidosis","text":"Phenotype: Sarcoidosis
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.321
N cases: 4041
N controls: 371255"}
{"pvalue":0.39,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Severe combined immunodeficiency [SCID] with reticular dysgenesis","text":"Phenotype: Severe combined immunodeficiency [SCID] with reticular dysgenesis
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.39
N cases: 82
N controls: 371255"}
{"pvalue":0.574,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Secondary polycythaemia","text":"Phenotype: Secondary polycythaemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.574
N cases: 608
N controls: 370400"}
{"pvalue":0.834,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Secondary thrombocytopenia","text":"Phenotype: Secondary thrombocytopenia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.834
N cases: 298
N controls: 371504"}
{"pvalue":0.561,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Hereditary sideroblastic anaemia","text":"Phenotype: Hereditary sideroblastic anaemia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.561
N cases: 103
N controls: 362319"}
{"pvalue":0.403,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Other sideroblastic anaemias","text":"Phenotype: Other sideroblastic anaemias
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.403
N cases: 102
N controls: 362319"}
{"pvalue":0.0572,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Diseases of spleen","text":"Phenotype: Diseases of spleen
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0572
N cases: 397
N controls: 370400"}
{"pvalue":0.106,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified diseases of spleen","text":"Phenotype: Other and unspecified diseases of spleen
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.106
N cases: 92
N controls: 370400"}
{"pvalue":0.801,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Thrombocytopenia, unspecified","text":"Phenotype: Thrombocytopenia, unspecified
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.801
N cases: 1869
N controls: 371504"}
{"pvalue":0.0274,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Von Willebrand disease","text":"Phenotype: Von Willebrand disease
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0274
N cases: 336
N controls: 371504"}
{"pvalue":0.877,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Other and unspecified disorders of white blood cells","text":"Phenotype: Other and unspecified disorders of white blood cells
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.877
N cases: 1077
N controls: 370400"}
{"pvalue":0.601,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Drug-induced adrenocortical insufficiency","text":"Phenotype: Drug-induced adrenocortical insufficiency
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.601
N cases: 403
N controls: 376874"}
{"pvalue":0.348,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Drug-induced cataract","text":"Phenotype: Drug-induced cataract
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.348
N cases: 621
N controls: 376656"}
{"pvalue":0.232,"sign":1,"group":"G6: Nervous system diseases","label":"Drug-induced dystonia","text":"Phenotype: Drug-induced dystonia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.232
N cases: 86
N controls: 377191"}
{"pvalue":0.851,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Drug-induced gout","text":"Phenotype: Drug-induced gout
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.851
N cases: 121
N controls: 377156"}
{"pvalue":0.889,"sign":1,"group":"G6: Nervous system diseases","label":"Drug-induced headache, not elsewhere classified","text":"Phenotype: Drug-induced headache, not elsewhere classified
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.889
N cases: 132
N controls: 377145"}
{"pvalue":0.21,"sign":-1,"group":"D3: Blood and blood-forming organ diseases","label":"Drug-induced neutropenia","text":"Phenotype: Drug-induced neutropenia
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.21
N cases: 1978
N controls: 375299"}
{"pvalue":0.99,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Drug-induced osteoporosis","text":"Phenotype: Drug-induced osteoporosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.99
N cases: 289
N controls: 376988"}
{"pvalue":0.647,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Drug-induced systemic lupus erythematosus","text":"Phenotype: Drug-induced systemic lupus erythematosus
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.647
N cases: 191
N controls: 377086"}
{"pvalue":0.368,"sign":-1,"group":"G6: Nervous system diseases","label":"Drug-induced tremor","text":"Phenotype: Drug-induced tremor
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.368
N cases: 151
N controls: 377126"}
{"pvalue":0.948,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Dry age-related macular degeneration (includes geographic atrophy)","text":"Phenotype: Dry age-related macular degeneration (includes geographic atrophy)
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.948
N cases: 6065
N controls: 251042"}
{"pvalue":0.409,"sign":-1,"group":"K11: Digestive system diseases","label":"Duodenal ulcer - Unspecified as acute or chronic, without haemorrhage or perforation, drug-induced","text":"Phenotype: Duodenal ulcer - Unspecified as acute or chronic, without haemorrhage or perforation, drug-induced
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.409
N cases: 106
N controls: 377171"}
{"pvalue":0.678,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Acidosis","text":"Phenotype: Acidosis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.678
N cases: 479
N controls: 324150"}
{"pvalue":0.639,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Acromegaly and pituitary gigantism","text":"Phenotype: Acromegaly and pituitary gigantism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.639
N cases: 183
N controls: 361988"}
{"pvalue":0.85,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Adrenocortical insufficiency","text":"Phenotype: Adrenocortical insufficiency
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.85
N cases: 923
N controls: 361988"}
{"pvalue":0.405,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other adrenocortical overactivity","text":"Phenotype: Other adrenocortical overactivity
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.405
N cases: 146
N controls: 361988"}
{"pvalue":0.424,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Adrenomedullary hyperfunction","text":"Phenotype: Adrenomedullary hyperfunction
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.424
N cases: 80
N controls: 361988"}
{"pvalue":0.336,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of adrenal gland, other and/or unspecified","text":"Phenotype: Disorders of adrenal gland, other and/or unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.336
N cases: 129
N controls: 361988"}
{"pvalue":0.29,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Adrenogenital disorders","text":"Phenotype: Adrenogenital disorders
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.29
N cases: 127
N controls: 361988"}
{"pvalue":0.0817,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other disorders of amino-acid metabolism","text":"Phenotype: Other disorders of amino-acid metabolism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0817
N cases: 127
N controls: 324150"}
{"pvalue":0.151,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Amyloidosis, other/unspecified","text":"Phenotype: Amyloidosis, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.151
N cases: 413
N controls: 324150"}
{"pvalue":0.388,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Secondary systemic amyloidosis","text":"Phenotype: Secondary systemic amyloidosis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.388
N cases: 88
N controls: 324150"}
{"pvalue":0.743,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Syndrome of inappropriate secretion of antidiuretic hormone","text":"Phenotype: Syndrome of inappropriate secretion of antidiuretic hormone
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.743
N cases: 119
N controls: 361988"}
{"pvalue":0.406,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of aromatic amino-acid metabolism","text":"Phenotype: Disorders of aromatic amino-acid metabolism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.406
N cases: 93
N controls: 324150"}
{"pvalue":0.206,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other disorders of carbohydrate metabolism","text":"Phenotype: Other disorders of carbohydrate metabolism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.206
N cases: 127
N controls: 324150"}
{"pvalue":0.922,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorder of carbohydrate metabolism, other/unspecified","text":"Phenotype: Disorder of carbohydrate metabolism, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.922
N cases: 84
N controls: 324150"}
{"pvalue":0.0114,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Carcinoid syndrome","text":"Phenotype: Carcinoid syndrome
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0114
N cases: 249
N controls: 361988"}
{"pvalue":0.885,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Congenital iodine-deficiency syndrome/hypothyroidism","text":"Phenotype: Congenital iodine-deficiency syndrome/hypothyroidism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.885
N cases: 877
N controls: 320703"}
{"pvalue":0.679,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Cushing syndrome","text":"Phenotype: Cushing syndrome
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.679
N cases: 293
N controls: 361988"}
{"pvalue":0.503,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Delayed puberty","text":"Phenotype: Delayed puberty
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.503
N cases: 213
N controls: 361988"}
{"pvalue":0.983,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Diabetes insipidus","text":"Phenotype: Diabetes insipidus
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.983
N cases: 245
N controls: 361988"}
{"pvalue":0.374,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of puberty","text":"Phenotype: Disorders of puberty
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.374
N cases: 412
N controls: 361988"}
{"pvalue":0.127,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 1 diabetes with coma","text":"Phenotype: Type 1 diabetes with coma
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.127
N cases: 2050
N controls: 308280"}
{"pvalue":0.274,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 1 diabetes with ketoacidosis","text":"Phenotype: Type 1 diabetes with ketoacidosis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.274
N cases: 2102
N controls: 308280"}
{"pvalue":0.264,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 1 diabetes with other specified/multiple/unspecified complications","text":"Phenotype: Type 1 diabetes with other specified/multiple/unspecified complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.264
N cases: 6234
N controls: 308280"}
{"pvalue":0.359,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 1 diabetes with neurological complications","text":"Phenotype: Type 1 diabetes with neurological complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.359
N cases: 1077
N controls: 308280"}
{"pvalue":0.0875,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 1 diabetes with ophthalmic complications","text":"Phenotype: Type 1 diabetes with ophthalmic complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0875
N cases: 5202
N controls: 308280"}
{"pvalue":0.808,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 1 diabetes with peripheral circulatory complications","text":"Phenotype: Type 1 diabetes with peripheral circulatory complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.808
N cases: 669
N controls: 308280"}
{"pvalue":0.556,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 1 diabetes with renal complications","text":"Phenotype: Type 1 diabetes with renal complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.556
N cases: 1579
N controls: 308280"}
{"pvalue":0.718,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 2 diabetes with coma","text":"Phenotype: Type 2 diabetes with coma
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.718
N cases: 4709
N controls: 308280"}
{"pvalue":0.873,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 2 diabetes with ketoacidosis","text":"Phenotype: Type 2 diabetes with ketoacidosis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.873
N cases: 657
N controls: 308280"}
{"pvalue":0.00625,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 2 diabetes with other specified/multiple/unspecified complications","text":"Phenotype: Type 2 diabetes with other specified/multiple/unspecified complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00625
N cases: 46373
N controls: 308280"}
{"pvalue":0.631,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 2 diabetes with neurological complications","text":"Phenotype: Type 2 diabetes with neurological complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.631
N cases: 1894
N controls: 308280"}
{"pvalue":0.0314,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 2 diabetes with ophthalmic complications","text":"Phenotype: Type 2 diabetes with ophthalmic complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0314
N cases: 4172
N controls: 308280"}
{"pvalue":0.136,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 2 diabetes with peripheral circulatory complications","text":"Phenotype: Type 2 diabetes with peripheral circulatory complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.136
N cases: 2179
N controls: 308280"}
{"pvalue":0.601,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Type 2 diabetes with renal complications","text":"Phenotype: Type 2 diabetes with renal complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.601
N cases: 2684
N controls: 308280"}
{"pvalue":0.536,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified diabetes with coma","text":"Phenotype: Unspecified diabetes with coma
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.536
N cases: 158
N controls: 308280"}
{"pvalue":0.214,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified diabetes","text":"Phenotype: Unspecified diabetes
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.214
N cases: 7455
N controls: 308280"}
{"pvalue":0.816,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified diabetes with ketoacidosis","text":"Phenotype: Unspecified diabetes with ketoacidosis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.816
N cases: 259
N controls: 308280"}
{"pvalue":0.928,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified diabetes with multiple/unspecified complications","text":"Phenotype: Unspecified diabetes with multiple/unspecified complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.928
N cases: 1039
N controls: 308280"}
{"pvalue":0.981,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified diabetes with neurological complications","text":"Phenotype: Unspecified diabetes with neurological complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.981
N cases: 104
N controls: 308280"}
{"pvalue":0.35,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified diabetes without complications","text":"Phenotype: Unspecified diabetes without complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.35
N cases: 2855
N controls: 308280"}
{"pvalue":0.329,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified diabetes with ophthalmic complications","text":"Phenotype: Unspecified diabetes with ophthalmic complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.329
N cases: 88
N controls: 308280"}
{"pvalue":0.981,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified diabetes with other specified complications","text":"Phenotype: Unspecified diabetes with other specified complications
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.981
N cases: 138
N controls: 308280"}
{"pvalue":0.881,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other endocrine disorders","text":"Phenotype: Other endocrine disorders
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.881
N cases: 1576
N controls: 361988"}
{"pvalue":0.124,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Endocrine disorders, other/unspecified","text":"Phenotype: Endocrine disorders, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.124
N cases: 588
N controls: 361988"}
{"pvalue":0.679,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of other endocrine glands","text":"Phenotype: Disorders of other endocrine glands
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.679
N cases: 15289
N controls: 361988"}
{"pvalue":0.908,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Postprocedural endocrine and metabolic disorders, not elsewhere classified","text":"Phenotype: Postprocedural endocrine and metabolic disorders, not elsewhere classified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.908
N cases: 3383
N controls: 324150"}
{"pvalue":0.665,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Iron deficiency","text":"Phenotype: Iron deficiency
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.665
N cases: 340
N controls: 354812"}
{"pvalue":0.463,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Familial hypercholesterolemia","text":"Phenotype: Familial hypercholesterolemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.463
N cases: 4965
N controls: 324150"}
{"pvalue":0.222,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Familial hypercholesterolemia, with ischemic heart disease","text":"Phenotype: Familial hypercholesterolemia, with ischemic heart disease
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.222
N cases: 2757
N controls: 313533"}
{"pvalue":0.97,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other disorders of fluid, electrolyte and acid-base balance","text":"Phenotype: Other disorders of fluid, electrolyte and acid-base balance
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.97
N cases: 9694
N controls: 324150"}
{"pvalue":0.158,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other disorders of electrolyte and fluid balance, not elsewhere classified","text":"Phenotype: Other disorders of electrolyte and fluid balance, not elsewhere classified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.158
N cases: 226
N controls: 324150"}
{"pvalue":0.431,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Gilbert syndrome","text":"Phenotype: Gilbert syndrome
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.431
N cases: 180
N controls: 324150"}
{"pvalue":0.231,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other disorders of glucose regulation and pancreatic internal secretion","text":"Phenotype: Other disorders of glucose regulation and pancreatic internal secretion
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.231
N cases: 2583
N controls: 374694"}
{"pvalue":0.634,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Nontoxic diffuse goitre","text":"Phenotype: Nontoxic diffuse goitre
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.634
N cases: 838
N controls: 320703"}
{"pvalue":0.19,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Nontoxic multinodular goitre","text":"Phenotype: Nontoxic multinodular goitre
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.19
N cases: 6149
N controls: 320703"}
{"pvalue":0.413,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other and/or unspecified nontoxic goitre","text":"Phenotype: Other and/or unspecified nontoxic goitre
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.413
N cases: 2334
N controls: 320703"}
{"pvalue":0.722,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Nontoxic single thyroid nodule","text":"Phenotype: Nontoxic single thyroid nodule
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.722
N cases: 2027
N controls: 320703"}
{"pvalue":0.565,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Graves ophthalmopathy, strict","text":"Phenotype: Graves ophthalmopathy, strict
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.565
N cases: 561
N controls: 376716"}
{"pvalue":0.882,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Graves disease, strict definition","text":"Phenotype: Graves disease, strict definition
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.882
N cases: 2836
N controls: 374441"}
{"pvalue":0.337,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperaldosteronism","text":"Phenotype: Hyperaldosteronism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.337
N cases: 690
N controls: 361988"}
{"pvalue":0.0271,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Pure hypercholesterolaemia","text":"Phenotype: Pure hypercholesterolaemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0271
N cases: 25928
N controls: 324150"}
{"pvalue":0.681,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Pure hyperglyceridaemia","text":"Phenotype: Pure hyperglyceridaemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.681
N cases: 565
N controls: 324150"}
{"pvalue":0.788,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperkalaemia","text":"Phenotype: Hyperkalaemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.788
N cases: 1455
N controls: 324150"}
{"pvalue":0.261,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Mixed hyperlipidaemia","text":"Phenotype: Mixed hyperlipidaemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.261
N cases: 1084
N controls: 324150"}
{"pvalue":0.786,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperlipidaemia, other/unspecified","text":"Phenotype: Hyperlipidaemia, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.786
N cases: 12304
N controls: 324150"}
{"pvalue":0.0503,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperosmolality and hypernatraemia","text":"Phenotype: Hyperosmolality and hypernatraemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0503
N cases: 328
N controls: 324150"}
{"pvalue":0.0617,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperparathyroidism","text":"Phenotype: Hyperparathyroidism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0617
N cases: 5590
N controls: 361988"}
{"pvalue":0.439,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperfunction of pituitary gland","text":"Phenotype: Hyperfunction of pituitary gland
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.439
N cases: 1460
N controls: 361988"}
{"pvalue":0.836,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperprolactinaemia, drug-induced","text":"Phenotype: Hyperprolactinaemia, drug-induced
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.836
N cases: 160
N controls: 377117"}
{"pvalue":0.386,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperprolactinaemia","text":"Phenotype: Hyperprolactinaemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.386
N cases: 1014
N controls: 361988"}
{"pvalue":0.18,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease","text":"Phenotype: Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.18
N cases: 116
N controls: 324150"}
{"pvalue":0.753,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Nondiabetic hypoglycaemic coma","text":"Phenotype: Nondiabetic hypoglycaemic coma
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.753
N cases: 122
N controls: 374694"}
{"pvalue":0.00846,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Drug-induced hypoglycaemia without coma","text":"Phenotype: Drug-induced hypoglycaemia without coma
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00846
N cases: 445
N controls: 374694"}
{"pvalue":0.149,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hypokalaemia","text":"Phenotype: Hypokalaemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.149
N cases: 3278
N controls: 324150"}
{"pvalue":0.407,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hypo-osmolality and hyponatraemia","text":"Phenotype: Hypo-osmolality and hyponatraemia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.407
N cases: 5137
N controls: 324150"}
{"pvalue":0.451,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hypoparathyroidism","text":"Phenotype: Hypoparathyroidism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.451
N cases: 899
N controls: 361988"}
{"pvalue":0.139,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hypopituitarism","text":"Phenotype: Hypopituitarism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.139
N cases: 1902
N controls: 361988"}
{"pvalue":0.955,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hypothyroidism, autoimmune, DX-based","text":"Phenotype: Hypothyroidism, autoimmune, DX-based
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.955
N cases: 92
N controls: 376788"}
{"pvalue":0.166,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hypothyroidism, strict autoimmune","text":"Phenotype: Hypothyroidism, strict autoimmune
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.166
N cases: 40926
N controls: 274069"}
{"pvalue":0.33,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Postinfectious hypothyroidism","text":"Phenotype: Postinfectious hypothyroidism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.33
N cases: 158
N controls: 320703"}
{"pvalue":0.611,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hypothyroidism due to medicaments and other exogenous substances","text":"Phenotype: Hypothyroidism due to medicaments and other exogenous substances
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.611
N cases: 258
N controls: 320703"}
{"pvalue":0.434,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of iron metabolism","text":"Phenotype: Disorders of iron metabolism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.434
N cases: 324
N controls: 324150"}
{"pvalue":0.37,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Lactose intolerance, other/unspecified","text":"Phenotype: Lactose intolerance, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.37
N cases: 691
N controls: 324150"}
{"pvalue":0.0253,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of lipoprotein metabolism and other lipidaemias","text":"Phenotype: Disorders of lipoprotein metabolism and other lipidaemias
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0253
N cases: 37742
N controls: 324150"}
{"pvalue":0.803,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorder of lipoprotein metabolism, unspecified","text":"Phenotype: Disorder of lipoprotein metabolism, unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.803
N cases: 3989
N controls: 324150"}
{"pvalue":0.534,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Localized adiposity","text":"Phenotype: Localized adiposity
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.534
N cases: 132
N controls: 355786"}
{"pvalue":0.949,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Malnutrition","text":"Phenotype: Malnutrition
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.949
N cases: 469
N controls: 376808"}
{"pvalue":0.0391,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Metabolic disorders","text":"Phenotype: Metabolic disorders
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0391
N cases: 53127
N controls: 324150"}
{"pvalue":0.313,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of magnesium metabolism","text":"Phenotype: Disorders of magnesium metabolism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.313
N cases: 154
N controls: 324150"}
{"pvalue":0.615,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of mineral metabolism","text":"Phenotype: Disorders of mineral metabolism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.615
N cases: 2215
N controls: 324150"}
{"pvalue":0.111,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Nontoxic goitre/thyroid nodule","text":"Phenotype: Nontoxic goitre/thyroid nodule
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.111
N cases: 9485
N controls: 367792"}
{"pvalue":0.476,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Other specified/unspecified nutritional deficiencies","text":"Phenotype: Other specified/unspecified nutritional deficiencies
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.476
N cases: 205
N controls: 354812"}
{"pvalue":0.85,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Obesity due to excess calories","text":"Phenotype: Obesity due to excess calories
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.85
N cases: 15045
N controls: 355902"}
{"pvalue":0.145,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Drug-induced obesity","text":"Phenotype: Drug-induced obesity
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.145
N cases: 240
N controls: 355902"}
{"pvalue":0.56,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Obesity","text":"Phenotype: Obesity
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.56
N cases: 21375
N controls: 355786"}
{"pvalue":0.355,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Obesity, other/unspecified","text":"Phenotype: Obesity, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.355
N cases: 11025
N controls: 355902"}
{"pvalue":0.477,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Extreme obesity with alveolar hypoventilation","text":"Phenotype: Extreme obesity with alveolar hypoventilation
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.477
N cases: 1064
N controls: 355902"}
{"pvalue":0.0724,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Ovarian dysfunction","text":"Phenotype: Ovarian dysfunction
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0724
N cases: 2010
N controls: 200581"}
{"pvalue":0.447,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Ovarian dysfunction, other/unspecified","text":"Phenotype: Ovarian dysfunction, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.447
N cases: 127
N controls: 200581"}
{"pvalue":0.51,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Primary ovarian failure","text":"Phenotype: Primary ovarian failure
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.51
N cases: 469
N controls: 200581"}
{"pvalue":0.27,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorder of pancreatic internal secretion, other and/or unspecified","text":"Phenotype: Disorder of pancreatic internal secretion, other and/or unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.27
N cases: 188
N controls: 374694"}
{"pvalue":0.489,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of parathyroid gland, other and/or unspecified","text":"Phenotype: Disorders of parathyroid gland, other and/or unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.489
N cases: 193
N controls: 361988"}
{"pvalue":0.203,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of parathyroid gland","text":"Phenotype: Disorders of parathyroid gland
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.203
N cases: 6362
N controls: 361988"}
{"pvalue":0.0378,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Polycystic ovarian syndrome, broad definition","text":"Phenotype: Polycystic ovarian syndrome, broad definition
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0378
N cases: 3205
N controls: 204492"}
{"pvalue":0.0488,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Polycystic ovarian syndrome, consortium definition","text":"Phenotype: Polycystic ovarian syndrome, consortium definition
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0488
N cases: 31548
N controls: 179322"}
{"pvalue":0.0365,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Polycystic ovarian syndrome","text":"Phenotype: Polycystic ovarian syndrome
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0365
N cases: 1424
N controls: 200581"}
{"pvalue":0.0157,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of phosphorus metabolism and phosphatases","text":"Phenotype: Disorders of phosphorus metabolism and phosphatases
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0157
N cases: 109
N controls: 324150"}
{"pvalue":0.596,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of pituitary gland, other and/or unspecified","text":"Phenotype: Disorders of pituitary gland, other and/or unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.596
N cases: 148
N controls: 361988"}
{"pvalue":0.471,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of plasma-protein metabolism, not elsewhere classified","text":"Phenotype: Disorders of plasma-protein metabolism, not elsewhere classified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.471
N cases: 176
N controls: 324150"}
{"pvalue":0.0893,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of porphyrin and bilirubin metabolism","text":"Phenotype: Disorders of porphyrin and bilirubin metabolism
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0893
N cases: 284
N controls: 324150"}
{"pvalue":0.817,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Precocious central puberty","text":"Phenotype: Precocious central puberty
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.817
N cases: 171
N controls: 361988"}
{"pvalue":0.591,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Precocious puberty","text":"Phenotype: Precocious puberty
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.591
N cases: 123
N controls: 361988"}
{"pvalue":0.169,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Protein-energy malnutrition of moderate and mild degree","text":"Phenotype: Protein-energy malnutrition of moderate and mild degree
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.169
N cases: 193
N controls: 376808"}
{"pvalue":0.439,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Unspecified protein-energy malnutrition","text":"Phenotype: Unspecified protein-energy malnutrition
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.439
N cases: 116
N controls: 376808"}
{"pvalue":0.116,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of puberty, other/unspecified","text":"Phenotype: Disorders of puberty, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.116
N cases: 105
N controls: 361988"}
{"pvalue":0.584,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Short stature, not elsewhere classified","text":"Phenotype: Short stature, not elsewhere classified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.584
N cases: 611
N controls: 361988"}
{"pvalue":0.476,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of sphingolipid metabolism and other lipid storage disorders","text":"Phenotype: Disorders of sphingolipid metabolism and other lipid storage disorders
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.476
N cases: 98
N controls: 324150"}
{"pvalue":0.11,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Constitutional tall stature","text":"Phenotype: Constitutional tall stature
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.11
N cases: 126
N controls: 361988"}
{"pvalue":0.3,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Testicular dysfunction, other/unspecified","text":"Phenotype: Testicular dysfunction, other/unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.3
N cases: 91
N controls: 161407"}
{"pvalue":0.129,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Testicular hypofunction","text":"Phenotype: Testicular hypofunction
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.129
N cases: 667
N controls: 161407"}
{"pvalue":0.554,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Thiamine deficiency","text":"Phenotype: Thiamine deficiency
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.554
N cases: 137
N controls: 354812"}
{"pvalue":0.582,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorders of the thyroid gland","text":"Phenotype: Disorders of the thyroid gland
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.582
N cases: 56574
N controls: 320703"}
{"pvalue":0.167,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Acute thyroiditis","text":"Phenotype: Acute thyroiditis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.167
N cases: 109
N controls: 320703"}
{"pvalue":0.886,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Autoimmune thyroiditis","text":"Phenotype: Autoimmune thyroiditis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.886
N cases: 489
N controls: 320703"}
{"pvalue":0.0646,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Chronic thyroiditis","text":"Phenotype: Chronic thyroiditis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0646
N cases: 108
N controls: 320703"}
{"pvalue":0.0669,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Thyroiditis, unspecified","text":"Phenotype: Thyroiditis, unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0669
N cases: 403
N controls: 320703"}
{"pvalue":0.766,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Subacute thyroiditis","text":"Phenotype: Subacute thyroiditis
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.766
N cases: 742
N controls: 320703"}
{"pvalue":0.898,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Disorder of thyroid, unspecified","text":"Phenotype: Disorder of thyroid, unspecified
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.898
N cases: 286
N controls: 320703"}
{"pvalue":0.0482,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Thyrotoxicosis factitia","text":"Phenotype: Thyrotoxicosis factitia
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0482
N cases: 87
N controls: 369104"}
{"pvalue":0.624,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Thyrotoxicosis with diffuse goitre","text":"Phenotype: Thyrotoxicosis with diffuse goitre
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.624
N cases: 4462
N controls: 320703"}
{"pvalue":0.362,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Thyrotoxicosis with toxic multinodular goitre","text":"Phenotype: Thyrotoxicosis with toxic multinodular goitre
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.362
N cases: 1600
N controls: 369104"}
{"pvalue":0.437,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Thyrotoxicosis with toxic single thyroid nodule","text":"Phenotype: Thyrotoxicosis with toxic single thyroid nodule
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.437
N cases: 232
N controls: 369104"}
{"pvalue":0.245,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Vitamin A deficiency","text":"Phenotype: Vitamin A deficiency
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.245
N cases: 120
N controls: 354812"}
{"pvalue":0.525,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Deficiency of other B group vitamins","text":"Phenotype: Deficiency of other B group vitamins
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.525
N cases: 599
N controls: 354812"}
{"pvalue":0.00056,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Vitamin D deficiency","text":"Phenotype: Vitamin D deficiency
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.000562
N cases: 426
N controls: 354812"}
{"pvalue":0.0576,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Volume depletion","text":"Phenotype: Volume depletion
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0576
N cases: 2676
N controls: 324150"}
{"pvalue":0.0333,"sign":1,"group":"G6: Nervous system diseases","label":"Epileptic seizures related to drugs","text":"Phenotype: Epileptic seizures related to drugs
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0333
N cases: 91
N controls: 377186"}
{"pvalue":0.383,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Erectile dysfunction","text":"Phenotype: Erectile dysfunction
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.383
N cases: 2205
N controls: 164104"}
{"pvalue":0.0447,"sign":1,"group":"D3: Blood and blood-forming organ diseases","label":"Eosinophilic disease (BM)","text":"Phenotype: Eosinophilic disease (BM)
Category: D3: Blood and blood-forming organ diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0447
N cases: 398
N controls: 212144"}
{"pvalue":0.127,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Disturbance of activity and attention","text":"Phenotype: Disturbance of activity and attention
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.127
N cases: 2340
N controls: 371117"}
{"pvalue":0.736,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Agoraphobia","text":"Phenotype: Agoraphobia
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.736
N cases: 890
N controls: 337577"}
{"pvalue":0.842,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Acute alcohol intoxication","text":"Phenotype: Acute alcohol intoxication
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.842
N cases: 8957
N controls: 353355"}
{"pvalue":0.405,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Alcohol dependence","text":"Phenotype: Alcohol dependence
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.405
N cases: 9876
N controls: 353355"}
{"pvalue":0.3,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"All anxiety disorders","text":"Phenotype: All anxiety disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.3
N cases: 24662
N controls: 337577"}
{"pvalue":0.699,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Dementia in Alzheimer disease","text":"Phenotype: Dementia in Alzheimer disease
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.699
N cases: 5422
N controls: 356660"}
{"pvalue":0.235,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Anankastic personality disorder","text":"Phenotype: Anankastic personality disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.235
N cases: 1032
N controls: 366637"}
{"pvalue":0.487,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Anorexia (incl.atypical)","text":"Phenotype: Anorexia (incl.atypical)
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.487
N cases: 1897
N controls: 366876"}
{"pvalue":0.711,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Other anxiety disorders","text":"Phenotype: Other anxiety disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.711
N cases: 16887
N controls: 337577"}
{"pvalue":0.665,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Anxious personality disorder","text":"Phenotype: Anxious personality disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.665
N cases: 534
N controls: 366637"}
{"pvalue":0.96,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Behavioural syndromes associated with physiological disturbances and physical factors","text":"Phenotype: Behavioural syndromes associated with physiological disturbances and physical factors
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.96
N cases: 10401
N controls: 366876"}
{"pvalue":0.356,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Behavioural and emotional disorders with onset usually occurring in childhood and adolescence","text":"Phenotype: Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.356
N cases: 6160
N controls: 371117"}
{"pvalue":0.185,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Bipolar affective disorders","text":"Phenotype: Bipolar affective disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.185
N cases: 7006
N controls: 329192"}
{"pvalue":0.175,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Bulimia nervosa (incl. atypical)","text":"Phenotype: Bulimia nervosa (incl. atypical)
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.175
N cases: 1028
N controls: 366876"}
{"pvalue":0.299,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mental and behavioural disorders due to cannabinoids","text":"Phenotype: Mental and behavioural disorders due to cannabinoids
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.299
N cases: 939
N controls: 370672"}
{"pvalue":0.00432,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Delirium, not induced by alcohol and other psychoactive substances","text":"Phenotype: Delirium, not induced by alcohol and other psychoactive substances
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.00432
N cases: 3039
N controls: 356660"}
{"pvalue":0.331,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Persistent delusional disorders","text":"Phenotype: Persistent delusional disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.331
N cases: 2418
N controls: 364160"}
{"pvalue":0.107,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Dementia","text":"Phenotype: Dementia
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.107
N cases: 16499
N controls: 356660"}
{"pvalue":0.0572,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Dementia, including avohilmo","text":"Phenotype: Dementia, including avohilmo
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.0572
N cases: 17901
N controls: 359376"}
{"pvalue":0.0742,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Dementia in other diseases classified elsewhere","text":"Phenotype: Dementia in other diseases classified elsewhere
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.0742
N cases: 1157
N controls: 356660"}
{"pvalue":0.0189,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Unspecified dementia","text":"Phenotype: Unspecified dementia
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.0189
N cases: 3994
N controls: 356660"}
{"pvalue":0.882,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Dependent personality disorder","text":"Phenotype: Dependent personality disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.882
N cases: 610
N controls: 366637"}
{"pvalue":0.918,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Depression","text":"Phenotype: Depression
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.918
N cases: 43280
N controls: 329192"}
{"pvalue":0.593,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Depression or dysthymia","text":"Phenotype: Depression or dysthymia
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.593
N cases: 48847
N controls: 225483"}
{"pvalue":0.734,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Psychotic depression","text":"Phenotype: Psychotic depression
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.734
N cases: 1938
N controls: 228968"}
{"pvalue":0.687,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Recurrent or chronic depression","text":"Phenotype: Recurrent or chronic depression
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.687
N cases: 17227
N controls: 228647"}
{"pvalue":0.762,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Dissocial personality disorder","text":"Phenotype: Dissocial personality disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.762
N cases: 467
N controls: 366637"}
{"pvalue":0.193,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Dissociative [conversion] disorders","text":"Phenotype: Dissociative [conversion] disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.193
N cases: 1145
N controls: 337577"}
{"pvalue":0.184,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Other eating disorders","text":"Phenotype: Other eating disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.184
N cases: 1551
N controls: 366876"}
{"pvalue":0.462,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Emotional disorders and disorders of social functioning with onset specific to childhood","text":"Phenotype: Emotional disorders and disorders of social functioning with onset specific to childhood
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.462
N cases: 1620
N controls: 371117"}
{"pvalue":0.561,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Emotionally unstable personality disorder","text":"Phenotype: Emotionally unstable personality disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.561
N cases: 4183
N controls: 366637"}
{"pvalue":0.735,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Generalized anxiety disorder","text":"Phenotype: Generalized anxiety disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.735
N cases: 4666
N controls: 337577"}
{"pvalue":0.358,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Gender identity disorders","text":"Phenotype: Gender identity disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.358
N cases: 318
N controls: 366637"}
{"pvalue":0.49,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Habit and impulse disorders","text":"Phenotype: Habit and impulse disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.49
N cases: 459
N controls: 366637"}
{"pvalue":0.197,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mental and behavioural disorders due to hallucinogens","text":"Phenotype: Mental and behavioural disorders due to hallucinogens
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.197
N cases: 152
N controls: 370672"}
{"pvalue":0.495,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Histrionic personality disorder","text":"Phenotype: Histrionic personality disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.495
N cases: 142
N controls: 366637"}
{"pvalue":0.0116,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Hyperkinetic disorders (excl. ADHD)","text":"Phenotype: Hyperkinetic disorders (excl. ADHD)
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.0116
N cases: 462
N controls: 371117"}
{"pvalue":0.389,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Hypersomnia","text":"Phenotype: Hypersomnia
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.389
N cases: 373
N controls: 371145"}
{"pvalue":0.0336,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Insomnia","text":"Phenotype: Insomnia
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.0336
N cases: 4214
N controls: 371145"}
{"pvalue":0.402,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Kela-code for severe mental illness","text":"Phenotype: Kela-code for severe mental illness
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.402
N cases: 15451
N controls: 360114"}
{"pvalue":0.807,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Kela-code for behavioural disturbances in mental retardation","text":"Phenotype: Kela-code for behavioural disturbances in mental retardation
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.807
N cases: 225
N controls: 376064"}
{"pvalue":0.636,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Manic episode","text":"Phenotype: Manic episode
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.636
N cases: 934
N controls: 329192"}
{"pvalue":0.422,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mental disorders, not otherwise specified","text":"Phenotype: Mental disorders, not otherwise specified
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.422
N cases: 2631
N controls: 360114"}
{"pvalue":0.758,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Other mental disorders due to brain damage and dysfunction and to physical disease","text":"Phenotype: Other mental disorders due to brain damage and dysfunction and to physical disease
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.758
N cases: 3023
N controls: 356660"}
{"pvalue":0.535,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mild mental retardation","text":"Phenotype: Mild mental retardation
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.535
N cases: 733
N controls: 376064"}
{"pvalue":0.34,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mixed specific developmental disorders","text":"Phenotype: Mixed specific developmental disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.34
N cases: 595
N controls: 373484"}
{"pvalue":0.985,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mixed and other personality disorders","text":"Phenotype: Mixed and other personality disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.985
N cases: 2619
N controls: 366637"}
{"pvalue":0.986,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Moderate mental retardation","text":"Phenotype: Moderate mental retardation
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.986
N cases: 172
N controls: 376064"}
{"pvalue":0.574,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Mood [affective] disorders","text":"Phenotype: Mood [affective] disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.574
N cases: 48085
N controls: 329192"}
{"pvalue":0.504,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Other and unspecified mood [affective] disorders","text":"Phenotype: Other and unspecified mood [affective] disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.504
N cases: 2210
N controls: 329192"}
{"pvalue":0.372,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Other neurotic disorders","text":"Phenotype: Other neurotic disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.372
N cases: 1533
N controls: 337577"}
{"pvalue":0.591,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Obsessive-compulsive disorder","text":"Phenotype: Obsessive-compulsive disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.591
N cases: 1962
N controls: 337577"}
{"pvalue":0.516,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mental and behavioural disorders due to opioids","text":"Phenotype: Mental and behavioural disorders due to opioids
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.516
N cases: 1108
N controls: 370672"}
{"pvalue":0.716,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances","text":"Phenotype: Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.716
N cases: 2299
N controls: 370672"}
{"pvalue":0.315,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Other specified and unspecified personality disorders","text":"Phenotype: Other specified and unspecified personality disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.315
N cases: 3004
N controls: 366637"}
{"pvalue":0.922,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Other and unspecified mental retardation","text":"Phenotype: Other and unspecified mental retardation
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.922
N cases: 421
N controls: 376064"}
{"pvalue":0.162,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Panic disorder","text":"Phenotype: Panic disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.162
N cases: 4801
N controls: 337577"}
{"pvalue":0.475,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Paranoid personality disorder","text":"Phenotype: Paranoid personality disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.475
N cases: 559
N controls: 366637"}
{"pvalue":0.216,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Personality and behavioural disorders due to brain disease, damage and dysfunction","text":"Phenotype: Personality and behavioural disorders due to brain disease, damage and dysfunction
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.216
N cases: 417
N controls: 356660"}
{"pvalue":0.395,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Persistent mood disorders","text":"Phenotype: Persistent mood disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.395
N cases: 6756
N controls: 329192"}
{"pvalue":0.469,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Enduring personality changes","text":"Phenotype: Enduring personality changes
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.469
N cases: 115
N controls: 366637"}
{"pvalue":0.123,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Other and unspecified disorders of adult personality and behaviour","text":"Phenotype: Other and unspecified disorders of adult personality and behaviour
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.123
N cases: 162
N controls: 366637"}
{"pvalue":0.483,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Pervasive developmental disorders excl. Autism + Asperger","text":"Phenotype: Pervasive developmental disorders excl. Autism + Asperger
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.483
N cases: 289
N controls: 373484"}
{"pvalue":0.612,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Phobic anxiety disorders","text":"Phenotype: Phobic anxiety disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.612
N cases: 4303
N controls: 337577"}
{"pvalue":0.041,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Unspecified behavioural syndromes associated with physiological disturbances and physical factors +Physiological and behavioural factors associated with disorders of diseases classified elsewhere","text":"Phenotype: Unspecified behavioural syndromes associated with physiological disturbances and physical factors +Physiological and behavioural factors associated with disorders of diseases classified elsewhere
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.041
N cases: 471
N controls: 366876"}
{"pvalue":0.28,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Disorders of psychological development","text":"Phenotype: Disorders of psychological development
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.28
N cases: 3793
N controls: 373484"}
{"pvalue":0.554,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Other and unspecified disorders of psychological development","text":"Phenotype: Other and unspecified disorders of psychological development
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.554
N cases: 290
N controls: 373484"}
{"pvalue":0.801,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Other and unspecified nonorganic psychotic disorders","text":"Phenotype: Other and unspecified nonorganic psychotic disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.801
N cases: 7508
N controls: 364160"}
{"pvalue":0.376,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Acute and transient psychotic disorders","text":"Phenotype: Acute and transient psychotic disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.376
N cases: 4255
N controls: 364160"}
{"pvalue":0.304,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Post-traumatic stress disorder","text":"Phenotype: Post-traumatic stress disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.304
N cases: 2282
N controls: 337577"}
{"pvalue":0.272,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Schizoaffective disorder","text":"Phenotype: Schizoaffective disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.272
N cases: 2742
N controls: 364160"}
{"pvalue":0.519,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Schizotypal disorder","text":"Phenotype: Schizotypal disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.519
N cases: 798
N controls: 364160"}
{"pvalue":0.714,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Schizoid personality disorder","text":"Phenotype: Schizoid personality disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.714
N cases: 550
N controls: 366637"}
{"pvalue":0.493,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Specific development disorders of scholastic skills","text":"Phenotype: Specific development disorders of scholastic skills
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.493
N cases: 1148
N controls: 373484"}
{"pvalue":0.86,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Schizophrenia","text":"Phenotype: Schizophrenia
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.86
N cases: 6515
N controls: 364160"}
{"pvalue":0.292,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mental and behavioural disorders due to sedatives or hypnotics","text":"Phenotype: Mental and behavioural disorders due to sedatives or hypnotics
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.292
N cases: 2103
N controls: 370672"}
{"pvalue":0.156,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Sexual dysfunction","text":"Phenotype: Sexual dysfunction
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.156
N cases: 326
N controls: 366876"}
{"pvalue":0.684,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Sleep disorders, other/unspecified","text":"Phenotype: Sleep disorders, other/unspecified
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.684
N cases: 779
N controls: 371145"}
{"pvalue":0.83,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Disorder of the sleep-wake schedule","text":"Phenotype: Disorder of the sleep-wake schedule
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.83
N cases: 410
N controls: 371145"}
{"pvalue":0.402,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Social phobias","text":"Phenotype: Social phobias
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.402
N cases: 2482
N controls: 337577"}
{"pvalue":0.467,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Somatoform disorder","text":"Phenotype: Somatoform disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.467
N cases: 5164
N controls: 337577"}
{"pvalue":0.838,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Specific development disorders of speech and language","text":"Phenotype: Specific development disorders of speech and language
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.838
N cases: 1648
N controls: 373484"}
{"pvalue":0.261,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Mental and behavioural disorders due to use of other stimulants, including caffeine","text":"Phenotype: Mental and behavioural disorders due to use of other stimulants, including caffeine
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.261
N cases: 856
N controls: 370672"}
{"pvalue":0.89,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Other reaction to severe stress, and adjustment disorders","text":"Phenotype: Other reaction to severe stress, and adjustment disorders
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.89
N cases: 13913
N controls: 337577"}
{"pvalue":0.206,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Substance use, excluding alcohol","text":"Phenotype: Substance use, excluding alcohol
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.206
N cases: 6605
N controls: 353355"}
{"pvalue":0.358,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Unspecified organic or symptomatic mental disorder","text":"Phenotype: Unspecified organic or symptomatic mental disorder
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.358
N cases: 97
N controls: 356660"}
{"pvalue":0.173,"sign":-1,"group":"F5: Mental and behavioural disorders","label":"Vascular dementia","text":"Phenotype: Vascular dementia
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: -1
p-value: 0.173
N cases: 2335
N controls: 360778"}
{"pvalue":0.128,"sign":1,"group":"G6: Nervous system diseases","label":"Focal epilepsy","text":"Phenotype: Focal epilepsy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.128
N cases: 6842
N controls: 365537"}
{"pvalue":0.237,"sign":1,"group":"G6: Nervous system diseases","label":"Focal epilepsy, mode (most common among epilepsy diagnosis)","text":"Phenotype: Focal epilepsy, mode (most common among epilepsy diagnosis)
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.237
N cases: 1260
N controls: 365537"}
{"pvalue":0.0599,"sign":1,"group":"G6: Nervous system diseases","label":"Focal epilepsy, strict definition","text":"Phenotype: Focal epilepsy, strict definition
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0599
N cases: 6213
N controls: 365534"}
{"pvalue":0.00013,"sign":-1,"group":"I9: Circulatory system diseases","label":"Diseases of arteries, arterioles and capillaries (FINNGEN)","text":"Phenotype: Diseases of arteries, arterioles and capillaries (FINNGEN)
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.000129
N cases: 22224
N controls: 191924"}
{"pvalue":0.274,"sign":-1,"group":"G6: Nervous system diseases","label":"Alzheimer’s disease, wide definition","text":"Phenotype: Alzheimer’s disease, wide definition
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.274
N cases: 13393
N controls: 363884"}
{"pvalue":0.727,"sign":1,"group":"G6: Nervous system diseases","label":"Degeneration of the brain due to alcohol","text":"Phenotype: Degeneration of the brain due to alcohol
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.727
N cases: 592
N controls: 366632"}
{"pvalue":0.928,"sign":1,"group":"G6: Nervous system diseases","label":"Alcohol induced polyneuropathy","text":"Phenotype: Alcohol induced polyneuropathy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.928
N cases: 249
N controls: 370790"}
{"pvalue":0.543,"sign":1,"group":"G6: Nervous system diseases","label":"Motor neuron disease","text":"Phenotype: Motor neuron disease
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.543
N cases: 483
N controls: 170667"}
{"pvalue":0.725,"sign":-1,"group":"G6: Nervous system diseases","label":"Alzheimer disease","text":"Phenotype: Alzheimer disease
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.725
N cases: 9301
N controls: 367976"}
{"pvalue":0.414,"sign":-1,"group":"G6: Nervous system diseases","label":"Anoxic brain damage","text":"Phenotype: Anoxic brain damage
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.414
N cases: 368
N controls: 350251"}
{"pvalue":0.0134,"sign":-1,"group":"G6: Nervous system diseases","label":"Circumscribed brain atrophy","text":"Phenotype: Circumscribed brain atrophy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0134
N cases: 467
N controls: 366632"}
{"pvalue":0.722,"sign":-1,"group":"G6: Nervous system diseases","label":"Atypical facial pain","text":"Phenotype: Atypical facial pain
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.722
N cases: 1372
N controls: 330377"}
{"pvalue":0.9,"sign":1,"group":"G6: Nervous system diseases","label":"Autonomic disorders","text":"Phenotype: Autonomic disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.9
N cases: 549
N controls: 350251"}
{"pvalue":0.0903,"sign":-1,"group":"G6: Nervous system diseases","label":"Other degenerative diseases of the basal ganglia","text":"Phenotype: Other degenerative diseases of the basal ganglia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0903
N cases: 296
N controls: 367444"}
{"pvalue":0.466,"sign":-1,"group":"G6: Nervous system diseases","label":"Bell's palsy","text":"Phenotype: Bell's palsy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.466
N cases: 3453
N controls: 330377"}
{"pvalue":0.21,"sign":-1,"group":"G6: Nervous system diseases","label":"Benign intracranial hypertension","text":"Phenotype: Benign intracranial hypertension
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.21
N cases: 231
N controls: 350251"}
{"pvalue":0.31,"sign":1,"group":"G6: Nervous system diseases","label":"Brachial plexus disorders","text":"Phenotype: Brachial plexus disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.31
N cases: 2757
N controls: 330377"}
{"pvalue":0.0131,"sign":1,"group":"G6: Nervous system diseases","label":"Carpal tunnel syndrome","text":"Phenotype: Carpal tunnel syndrome
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0131
N cases: 22426
N controls: 330377"}
{"pvalue":0.444,"sign":1,"group":"G6: Nervous system diseases","label":"Cauda equina syndrome","text":"Phenotype: Cauda equina syndrome
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.444
N cases: 290
N controls: 373780"}
{"pvalue":0.89,"sign":1,"group":"G6: Nervous system diseases","label":"Causalgia","text":"Phenotype: Causalgia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.89
N cases: 438
N controls: 330377"}
{"pvalue":0.0953,"sign":-1,"group":"G6: Nervous system diseases","label":"Cerebral cysts","text":"Phenotype: Cerebral cysts
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0953
N cases: 1567
N controls: 350251"}
{"pvalue":0.682,"sign":1,"group":"G6: Nervous system diseases","label":"Cervical root disorders","text":"Phenotype: Cervical root disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.682
N cases: 190
N controls: 330377"}
{"pvalue":0.14,"sign":-1,"group":"G6: Nervous system diseases","label":"Cluster headache, strict, including avohilmo","text":"Phenotype: Cluster headache, strict, including avohilmo
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.14
N cases: 1297
N controls: 375980"}
{"pvalue":0.0828,"sign":-1,"group":"G6: Nervous system diseases","label":"Cluster headache, wide","text":"Phenotype: Cluster headache, wide
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0828
N cases: 1107
N controls: 287837"}
{"pvalue":0.81,"sign":1,"group":"G6: Nervous system diseases","label":"Intracranial and intraspinal abscess and granuloma","text":"Phenotype: Intracranial and intraspinal abscess and granuloma
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.81
N cases: 283
N controls: 374844"}
{"pvalue":0.668,"sign":-1,"group":"G6: Nervous system diseases","label":"Other disorders of central nervous system","text":"Phenotype: Other disorders of central nervous system
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.668
N cases: 285
N controls: 350251"}
{"pvalue":0.63,"sign":-1,"group":"G6: Nervous system diseases","label":"Cerebral palsy and other paralytic syndromes","text":"Phenotype: Cerebral palsy and other paralytic syndromes
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.63
N cases: 3497
N controls: 373780"}
{"pvalue":0.16,"sign":-1,"group":"G6: Nervous system diseases","label":"Cerebral palsy","text":"Phenotype: Cerebral palsy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.16
N cases: 482
N controls: 373780"}
{"pvalue":0.791,"sign":-1,"group":"G6: Nervous system diseases","label":"Other and unspecified degenerative diseases of nervous system","text":"Phenotype: Other and unspecified degenerative diseases of nervous system
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.791
N cases: 545
N controls: 366632"}
{"pvalue":0.757,"sign":1,"group":"G6: Nervous system diseases","label":"Senile degeneration of the brain, not elsewhere classified","text":"Phenotype: Senile degeneration of the brain, not elsewhere classified
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.757
N cases: 107
N controls: 366632"}
{"pvalue":0.348,"sign":-1,"group":"G6: Nervous system diseases","label":"Disorders of brain, other and unspecified","text":"Phenotype: Disorders of brain, other and unspecified
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.348
N cases: 266
N controls: 350251"}
{"pvalue":0.788,"sign":1,"group":"G6: Nervous system diseases","label":"Disorders of other and unspecified cranial nerves","text":"Phenotype: Disorders of other and unspecified cranial nerves
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.788
N cases: 142
N controls: 330377"}
{"pvalue":0.796,"sign":1,"group":"G6: Nervous system diseases","label":"Other acute disseminated demyelination","text":"Phenotype: Other acute disseminated demyelination
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.796
N cases: 277
N controls: 374678"}
{"pvalue":0.795,"sign":1,"group":"G6: Nervous system diseases","label":"Drug-induced polyneuropathy","text":"Phenotype: Drug-induced polyneuropathy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.795
N cases: 208
N controls: 370790"}
{"pvalue":0.164,"sign":1,"group":"G6: Nervous system diseases","label":"Dystonia","text":"Phenotype: Dystonia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.164
N cases: 1500
N controls: 367444"}
{"pvalue":0.288,"sign":-1,"group":"G6: Nervous system diseases","label":"Encephalopathy","text":"Phenotype: Encephalopathy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.288
N cases: 249
N controls: 350251"}
{"pvalue":0.581,"sign":-1,"group":"G6: Nervous system diseases","label":"Other encephalitis","text":"Phenotype: Other encephalitis
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.581
N cases: 705
N controls: 374844"}
{"pvalue":0.00722,"sign":1,"group":"G6: Nervous system diseases","label":"Episodal and paroxysmal disorders","text":"Phenotype: Episodal and paroxysmal disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00722
N cases: 89440
N controls: 287837"}
{"pvalue":0.0254,"sign":1,"group":"G6: Nervous system diseases","label":"Epilepsy","text":"Phenotype: Epilepsy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0254
N cases: 11740
N controls: 287837"}
{"pvalue":0.0566,"sign":1,"group":"G6: Nervous system diseases","label":"Other facial nerve disorders","text":"Phenotype: Other facial nerve disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0566
N cases: 756
N controls: 330377"}
{"pvalue":0.314,"sign":1,"group":"G6: Nervous system diseases","label":"Lesion of lateral popliteal nerve","text":"Phenotype: Lesion of lateral popliteal nerve
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.314
N cases: 1288
N controls: 330377"}
{"pvalue":0.0217,"sign":1,"group":"G6: Nervous system diseases","label":"Lesion of femoral nerve","text":"Phenotype: Lesion of femoral nerve
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0217
N cases: 208
N controls: 330377"}
{"pvalue":0.872,"sign":1,"group":"G6: Nervous system diseases","label":"Lesion of medial popliteal nerve","text":"Phenotype: Lesion of medial popliteal nerve
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.872
N cases: 92
N controls: 330377"}
{"pvalue":0.741,"sign":-1,"group":"G6: Nervous system diseases","label":"Guillain-Barre syndrome","text":"Phenotype: Guillain-Barre syndrome
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.741
N cases: 415
N controls: 370790"}
{"pvalue":0.846,"sign":-1,"group":"G6: Nervous system diseases","label":"Communicating hydrocephalus","text":"Phenotype: Communicating hydrocephalus
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.846
N cases: 488
N controls: 375610"}
{"pvalue":0.163,"sign":1,"group":"G6: Nervous system diseases","label":"Hydrocephalus in other diseases","text":"Phenotype: Hydrocephalus in other diseases
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.163
N cases: 145
N controls: 375610"}
{"pvalue":0.805,"sign":-1,"group":"G6: Nervous system diseases","label":"Normal-pressure hydrocephalus","text":"Phenotype: Normal-pressure hydrocephalus
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.805
N cases: 767
N controls: 375610"}
{"pvalue":0.898,"sign":1,"group":"G6: Nervous system diseases","label":"Obstructive hydrocephalus","text":"Phenotype: Obstructive hydrocephalus
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.898
N cases: 369
N controls: 375610"}
{"pvalue":0.792,"sign":1,"group":"G6: Nervous system diseases","label":"Other and unspecified hydrocephalus","text":"Phenotype: Other and unspecified hydrocephalus
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.792
N cases: 393
N controls: 375610"}
{"pvalue":0.00827,"sign":1,"group":"G6: Nervous system diseases","label":"Other headache syndromes","text":"Phenotype: Other headache syndromes
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00827
N cases: 15851
N controls: 287837"}
{"pvalue":0.227,"sign":1,"group":"G6: Nervous system diseases","label":"Hemiplegia","text":"Phenotype: Hemiplegia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.227
N cases: 1537
N controls: 373780"}
{"pvalue":0.643,"sign":1,"group":"G6: Nervous system diseases","label":"Hereditary ataxia","text":"Phenotype: Hereditary ataxia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.643
N cases: 339
N controls: 376185"}
{"pvalue":0.622,"sign":-1,"group":"G6: Nervous system diseases","label":"Hereditary motor and sensory neuropathy","text":"Phenotype: Hereditary motor and sensory neuropathy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.622
N cases: 218
N controls: 370790"}
{"pvalue":0.266,"sign":1,"group":"G6: Nervous system diseases","label":"Other and unspecified neuropathies","text":"Phenotype: Other and unspecified neuropathies
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.266
N cases: 112
N controls: 370790"}
{"pvalue":0.384,"sign":-1,"group":"G6: Nervous system diseases","label":"Horner syndrome","text":"Phenotype: Horner syndrome
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.384
N cases: 309
N controls: 376728"}
{"pvalue":0.631,"sign":1,"group":"G6: Nervous system diseases","label":"Hydrocephalus","text":"Phenotype: Hydrocephalus
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.631
N cases: 1667
N controls: 350251"}
{"pvalue":0.644,"sign":-1,"group":"G6: Nervous system diseases","label":"Intercostal neuropathy","text":"Phenotype: Intercostal neuropathy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.644
N cases: 207
N controls: 330377"}
{"pvalue":0.155,"sign":1,"group":"G6: Nervous system diseases","label":"Idiopathic peripheral autonomic neuropathy","text":"Phenotype: Idiopathic peripheral autonomic neuropathy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.155
N cases: 89
N controls: 376728"}
{"pvalue":0.723,"sign":-1,"group":"G6: Nervous system diseases","label":"Lumbosacral plexus disorders","text":"Phenotype: Lumbosacral plexus disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.723
N cases: 88
N controls: 330377"}
{"pvalue":0.843,"sign":-1,"group":"G6: Nervous system diseases","label":"Lumbosacral root disorders, not elsewhere classified","text":"Phenotype: Lumbosacral root disorders, not elsewhere classified
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.843
N cases: 353
N controls: 330377"}
{"pvalue":0.0525,"sign":1,"group":"G6: Nervous system diseases","label":"Other lesions of median nerve","text":"Phenotype: Other lesions of median nerve
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0525
N cases: 732
N controls: 330377"}
{"pvalue":0.629,"sign":1,"group":"G6: Nervous system diseases","label":"Bacterial meningitis","text":"Phenotype: Bacterial meningitis
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.629
N cases: 971
N controls: 374844"}
{"pvalue":0.809,"sign":-1,"group":"G6: Nervous system diseases","label":"Other meningitis","text":"Phenotype: Other meningitis
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.809
N cases: 411
N controls: 374844"}
{"pvalue":0.447,"sign":-1,"group":"G6: Nervous system diseases","label":"Viral meningitis","text":"Phenotype: Viral meningitis
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.447
N cases: 102
N controls: 374844"}
{"pvalue":0.11,"sign":-1,"group":"G6: Nervous system diseases","label":"Meralgia paraesthetica","text":"Phenotype: Meralgia paraesthetica
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.11
N cases: 849
N controls: 330377"}
{"pvalue":0.00178,"sign":1,"group":"G6: Nervous system diseases","label":"Migraine","text":"Phenotype: Migraine
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00178
N cases: 18477
N controls: 287837"}
{"pvalue":0.626,"sign":1,"group":"G6: Nervous system diseases","label":"Migraine without aura, drug-induced","text":"Phenotype: Migraine without aura, drug-induced
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.626
N cases: 321
N controls: 376956"}
{"pvalue":0.133,"sign":1,"group":"G6: Nervous system diseases","label":"Migraine without aura","text":"Phenotype: Migraine without aura
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.133
N cases: 6730
N controls: 287837"}
{"pvalue":0.183,"sign":1,"group":"G6: Nervous system diseases","label":"Migraine without aura and triptan purchases","text":"Phenotype: Migraine without aura and triptan purchases
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.183
N cases: 4989
N controls: 337890"}
{"pvalue":0.916,"sign":1,"group":"G6: Nervous system diseases","label":"Migraine with aura, drug-induced","text":"Phenotype: Migraine with aura, drug-induced
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.916
N cases: 307
N controls: 376970"}
{"pvalue":0.00909,"sign":1,"group":"G6: Nervous system diseases","label":"Migraine with aura","text":"Phenotype: Migraine with aura
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00909
N cases: 7917
N controls: 287837"}
{"pvalue":0.229,"sign":1,"group":"G6: Nervous system diseases","label":"Migraine with aura and triptan purchases","text":"Phenotype: Migraine with aura and triptan purchases
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.229
N cases: 4503
N controls: 337890"}
{"pvalue":0.555,"sign":1,"group":"G6: Nervous system diseases","label":"Mitochondrial myopathy","text":"Phenotype: Mitochondrial myopathy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.555
N cases: 98
N controls: 373848"}
{"pvalue":0.768,"sign":-1,"group":"G6: Nervous system diseases","label":"Other and unspecified mononeuropathies of lower limb","text":"Phenotype: Other and unspecified mononeuropathies of lower limb
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.768
N cases: 778
N controls: 330377"}
{"pvalue":0.851,"sign":1,"group":"G6: Nervous system diseases","label":"Other and unspecified mononeuropathies of upper limb","text":"Phenotype: Other and unspecified mononeuropathies of upper limb
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.851
N cases: 798
N controls: 330377"}
{"pvalue":0.602,"sign":-1,"group":"G6: Nervous system diseases","label":"Other and unspecified mononeuropathies, also in other diseases","text":"Phenotype: Other and unspecified mononeuropathies, also in other diseases
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.602
N cases: 874
N controls: 330377"}
{"pvalue":0.252,"sign":-1,"group":"G6: Nervous system diseases","label":"Monoplegia","text":"Phenotype: Monoplegia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.252
N cases: 385
N controls: 373780"}
{"pvalue":0.865,"sign":1,"group":"G6: Nervous system diseases","label":"MS-disease / Multiple Sclerosis","text":"Phenotype: MS-disease / Multiple Sclerosis
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.865
N cases: 2182
N controls: 373987"}
{"pvalue":0.453,"sign":1,"group":"G6: Nervous system diseases","label":"Other and unspecified primary disorders of muscles","text":"Phenotype: Other and unspecified primary disorders of muscles
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.453
N cases: 195
N controls: 373848"}
{"pvalue":0.636,"sign":-1,"group":"G6: Nervous system diseases","label":"Muscular dystrophy","text":"Phenotype: Muscular dystrophy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.636
N cases: 210
N controls: 373848"}
{"pvalue":0.412,"sign":1,"group":"G6: Nervous system diseases","label":"Myasthenia gravis","text":"Phenotype: Myasthenia gravis
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.412
N cases: 426
N controls: 373848"}
{"pvalue":0.506,"sign":-1,"group":"G6: Nervous system diseases","label":"Disorders of myoneural junction and muscle in diseases classified elsewhere","text":"Phenotype: Disorders of myoneural junction and muscle in diseases classified elsewhere
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.506
N cases: 200
N controls: 373848"}
{"pvalue":0.428,"sign":1,"group":"G6: Nervous system diseases","label":"Diseases of the myoneural junction and muscle","text":"Phenotype: Diseases of the myoneural junction and muscle
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.428
N cases: 3429
N controls: 373848"}
{"pvalue":0.894,"sign":1,"group":"G6: Nervous system diseases","label":"Other and unspecified myoneural disorders","text":"Phenotype: Other and unspecified myoneural disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.894
N cases: 98
N controls: 373848"}
{"pvalue":0.607,"sign":1,"group":"G6: Nervous system diseases","label":"Other and unspecified myopathies","text":"Phenotype: Other and unspecified myopathies
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.607
N cases: 2313
N controls: 373848"}
{"pvalue":0.319,"sign":1,"group":"G6: Nervous system diseases","label":"Myotonic disorders","text":"Phenotype: Myotonic disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.319
N cases: 206
N controls: 373848"}
{"pvalue":0.142,"sign":1,"group":"G6: Nervous system diseases","label":"Narcolepsy and cataplexy","text":"Phenotype: Narcolepsy and cataplexy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.142
N cases: 176
N controls: 287837"}
{"pvalue":0.169,"sign":1,"group":"G6: Nervous system diseases","label":"Nerve, nerve root and plexus disorders","text":"Phenotype: Nerve, nerve root and plexus disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.169
N cases: 46900
N controls: 330377"}
{"pvalue":0.777,"sign":-1,"group":"G6: Nervous system diseases","label":"Systemic atrophies primarily affecting the central nervous system","text":"Phenotype: Systemic atrophies primarily affecting the central nervous system
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.777
N cases: 1092
N controls: 376185"}
{"pvalue":0.781,"sign":-1,"group":"G6: Nervous system diseases","label":"Inflammatory diseases of the central nervous system","text":"Phenotype: Inflammatory diseases of the central nervous system
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.781
N cases: 2433
N controls: 374844"}
{"pvalue":0.535,"sign":1,"group":"G6: Nervous system diseases","label":"Other disorders of nervous system","text":"Phenotype: Other disorders of nervous system
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.535
N cases: 1754
N controls: 350251"}
{"pvalue":0.736,"sign":1,"group":"G6: Nervous system diseases","label":"Other demyelinating diseases of the central nervous system","text":"Phenotype: Other demyelinating diseases of the central nervous system
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.736
N cases: 1029
N controls: 374678"}
{"pvalue":0.913,"sign":-1,"group":"G6: Nervous system diseases","label":"Other neurological diseases","text":"Phenotype: Other neurological diseases
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.913
N cases: 27026
N controls: 350251"}
{"pvalue":0.289,"sign":-1,"group":"G6: Nervous system diseases","label":"Other and unspecified paralytic syndromes","text":"Phenotype: Other and unspecified paralytic syndromes
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.289
N cases: 359
N controls: 373780"}
{"pvalue":0.135,"sign":-1,"group":"G6: Nervous system diseases","label":"Paraplegia, diplegia of upper limbs","text":"Phenotype: Paraplegia, diplegia of upper limbs
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.135
N cases: 594
N controls: 373780"}
{"pvalue":0.123,"sign":-1,"group":"G6: Nervous system diseases","label":"Parkinson's disease","text":"Phenotype: Parkinson's disease
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.123
N cases: 4235
N controls: 373042"}
{"pvalue":0.0205,"sign":1,"group":"G6: Nervous system diseases","label":"Other disorders of peripheral nervous system","text":"Phenotype: Other disorders of peripheral nervous system
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0205
N cases: 143
N controls: 370790"}
{"pvalue":0.17,"sign":-1,"group":"G6: Nervous system diseases","label":"Lesion of plantar nerve","text":"Phenotype: Lesion of plantar nerve
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.17
N cases: 1784
N controls: 330377"}
{"pvalue":0.602,"sign":-1,"group":"G6: Nervous system diseases","label":"Other and unspecified polyneuropathies, also in other diseases","text":"Phenotype: Other and unspecified polyneuropathies, also in other diseases
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.602
N cases: 5553
N controls: 370790"}
{"pvalue":0.37,"sign":1,"group":"G6: Nervous system diseases","label":"Postprocedural disorders of nervous system","text":"Phenotype: Postprocedural disorders of nervous system
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.37
N cases: 2146
N controls: 350251"}
{"pvalue":0.225,"sign":-1,"group":"G6: Nervous system diseases","label":"Postviral fatigue syndrome","text":"Phenotype: Postviral fatigue syndrome
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.225
N cases: 169
N controls: 350251"}
{"pvalue":0.587,"sign":1,"group":"G6: Nervous system diseases","label":"Postzoster neuralgia","text":"Phenotype: Postzoster neuralgia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.587
N cases: 313
N controls: 330377"}
{"pvalue":0.211,"sign":-1,"group":"G6: Nervous system diseases","label":"Lesion of radial nerve","text":"Phenotype: Lesion of radial nerve
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.211
N cases: 1033
N controls: 330377"}
{"pvalue":0.178,"sign":1,"group":"G6: Nervous system diseases","label":"Other and unspecified nerve root and plexus disorders, also in other diseases","text":"Phenotype: Other and unspecified nerve root and plexus disorders, also in other diseases
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.178
N cases: 5294
N controls: 330377"}
{"pvalue":0.667,"sign":-1,"group":"G6: Nervous system diseases","label":"Lesion of sciatic nerve","text":"Phenotype: Lesion of sciatic nerve
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.667
N cases: 1367
N controls: 330377"}
{"pvalue":0.597,"sign":1,"group":"G6: Nervous system diseases","label":"Sleep apnoea","text":"Phenotype: Sleep apnoea
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.597
N cases: 38998
N controls: 336659"}
{"pvalue":0.453,"sign":1,"group":"G6: Nervous system diseases","label":"Sleep apnoea, including avohilmo","text":"Phenotype: Sleep apnoea, including avohilmo
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.453
N cases: 41704
N controls: 335573"}
{"pvalue":0.657,"sign":1,"group":"G6: Nervous system diseases","label":"Other sleep disorders","text":"Phenotype: Other sleep disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.657
N cases: 3219
N controls: 287837"}
{"pvalue":0.897,"sign":-1,"group":"G6: Nervous system diseases","label":"Other and unspecified spinal muscular atrophies","text":"Phenotype: Other and unspecified spinal muscular atrophies
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.897
N cases: 219
N controls: 376185"}
{"pvalue":0.706,"sign":1,"group":"G6: Nervous system diseases","label":"Other diseases of spinal cord","text":"Phenotype: Other diseases of spinal cord
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.706
N cases: 804
N controls: 350251"}
{"pvalue":0.791,"sign":-1,"group":"G6: Nervous system diseases","label":"Status epilepticus","text":"Phenotype: Status epilepticus
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.791
N cases: 1023
N controls: 287837"}
{"pvalue":0.0642,"sign":-1,"group":"G6: Nervous system diseases","label":"Tarsal tunnel syndrome","text":"Phenotype: Tarsal tunnel syndrome
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0642
N cases: 251
N controls: 330377"}
{"pvalue":0.168,"sign":-1,"group":"G6: Nervous system diseases","label":"Tetraplegia","text":"Phenotype: Tetraplegia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.168
N cases: 182
N controls: 373780"}
{"pvalue":0.722,"sign":1,"group":"G6: Nervous system diseases","label":"Trigeminal neuralgia","text":"Phenotype: Trigeminal neuralgia
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.722
N cases: 1599
N controls: 330377"}
{"pvalue":0.739,"sign":1,"group":"G6: Nervous system diseases","label":"Other and unspecified trigeminal disorders","text":"Phenotype: Other and unspecified trigeminal disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.739
N cases: 409
N controls: 330377"}
{"pvalue":0.562,"sign":1,"group":"G6: Nervous system diseases","label":"Lesion of ulnar nerve","text":"Phenotype: Lesion of ulnar nerve
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.562
N cases: 4151
N controls: 330377"}
{"pvalue":0.486,"sign":-1,"group":"G6: Nervous system diseases","label":"Extrapyramidal and movement disorders","text":"Phenotype: Extrapyramidal and movement disorders
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.486
N cases: 9833
N controls: 367444"}
{"pvalue":0.978,"sign":-1,"group":"G6: Nervous system diseases","label":"Other extrapyramidal and movement disorders in other diseases","text":"Phenotype: Other extrapyramidal and movement disorders in other diseases
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.978
N cases: 4594
N controls: 367444"}
{"pvalue":0.492,"sign":-1,"group":"G6: Nervous system diseases","label":"Generalized epilepsy","text":"Phenotype: Generalized epilepsy
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.492
N cases: 1298
N controls: 365534"}
{"pvalue":0.445,"sign":1,"group":"G6: Nervous system diseases","label":"Generalized epilepsy, mode (most common among epilepsy diagnosis)","text":"Phenotype: Generalized epilepsy, mode (most common among epilepsy diagnosis)
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.445
N cases: 2235
N controls: 365537"}
{"pvalue":0.227,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Generalized skin eruption due to drugs and medicaments","text":"Phenotype: Generalized skin eruption due to drugs and medicaments
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.227
N cases: 1051
N controls: 376226"}
{"pvalue":0.938,"sign":1,"group":"G6: Nervous system diseases","label":"Generalized epilepsy, strict definition","text":"Phenotype: Generalized epilepsy, strict definition
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.938
N cases: 669
N controls: 365534"}
{"pvalue":0.575,"sign":1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Graves ophthalmopathy","text":"Phenotype: Graves ophthalmopathy
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.575
N cases: 643
N controls: 376634"}
{"pvalue":0.00016,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Allergic conjunctivitis","text":"Phenotype: Allergic conjunctivitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.000155
N cases: 20958
N controls: 356319"}
{"pvalue":0.975,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Amblyopia ex anopsia","text":"Phenotype: Amblyopia ex anopsia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.975
N cases: 1046
N controls: 360091"}
{"pvalue":0.902,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Age-related macular degeneration (whether dry or wet)","text":"Phenotype: Age-related macular degeneration (whether dry or wet)
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.902
N cases: 8913
N controls: 348936"}
{"pvalue":0.963,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Anisometropia and aniseikonia","text":"Phenotype: Anisometropia and aniseikonia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.963
N cases: 793
N controls: 361237"}
{"pvalue":0.519,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Anomalies of pupillary function","text":"Phenotype: Anomalies of pupillary function
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.519
N cases: 509
N controls: 373254"}
{"pvalue":0.877,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Aphakia","text":"Phenotype: Aphakia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.877
N cases: 471
N controls: 312864"}
{"pvalue":0.132,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Astigmatism","text":"Phenotype: Astigmatism
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.132
N cases: 1502
N controls: 361237"}
{"pvalue":0.905,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Background retinopathy and retinal vascular changes","text":"Phenotype: Background retinopathy and retinal vascular changes
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.905
N cases: 533
N controls: 344569"}
{"pvalue":0.507,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other and unspecified disorders of binocular movement","text":"Phenotype: Other and unspecified disorders of binocular movement
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.507
N cases: 135
N controls: 361237"}
{"pvalue":0.747,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of binocular movement","text":"Phenotype: Other disorders of binocular movement
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.747
N cases: 581
N controls: 361237"}
{"pvalue":0.135,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of binocular vision","text":"Phenotype: Other disorders of binocular vision
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.135
N cases: 327
N controls: 360091"}
{"pvalue":0.634,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Blepharochalasis","text":"Phenotype: Blepharochalasis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.634
N cases: 8547
N controls: 344684"}
{"pvalue":0.762,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Visual impairment including blindness (binocular or monocular)","text":"Phenotype: Visual impairment including blindness (binocular or monocular)
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.762
N cases: 1882
N controls: 360091"}
{"pvalue":0.224,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Blindness, monocular","text":"Phenotype: Blindness, monocular
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.224
N cases: 223
N controls: 360091"}
{"pvalue":0.112,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Bullous keratopathy","text":"Phenotype: Bullous keratopathy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.112
N cases: 200
N controls: 357814"}
{"pvalue":0.405,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other cataract","text":"Phenotype: Other cataract
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.405
N cases: 17699
N controls: 312864"}
{"pvalue":0.317,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Senile cataract","text":"Phenotype: Senile cataract
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.317
N cases: 59522
N controls: 312864"}
{"pvalue":0.281,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Central retinal artery occlusion","text":"Phenotype: Central retinal artery occlusion
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.281
N cases: 546
N controls: 344569"}
{"pvalue":0.332,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Chalazion","text":"Phenotype: Chalazion
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.332
N cases: 3389
N controls: 344684"}
{"pvalue":0.849,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Choroidal haemorrhage and rupture","text":"Phenotype: Choroidal haemorrhage and rupture
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.849
N cases: 80
N controls: 344569"}
{"pvalue":0.864,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Chorioretinal inflammation","text":"Phenotype: Chorioretinal inflammation
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.864
N cases: 761
N controls: 344569"}
{"pvalue":0.0918,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other specified and unspecified disorders of choroid","text":"Phenotype: Other specified and unspecified disorders of choroid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0918
N cases: 95
N controls: 344569"}
{"pvalue":0.126,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of choroid","text":"Phenotype: Other disorders of choroid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.126
N cases: 358
N controls: 344569"}
{"pvalue":0.72,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Disorders of choroid and retina","text":"Phenotype: Disorders of choroid and retina
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.72
N cases: 32708
N controls: 344569"}
{"pvalue":0.213,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Chorioretinal scars","text":"Phenotype: Chorioretinal scars
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.213
N cases: 82
N controls: 344569"}
{"pvalue":0.238,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"conjunctival haemorrhage","text":"Phenotype: conjunctival haemorrhage
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.238
N cases: 1861
N controls: 345122"}
{"pvalue":0.407,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other specified and unspecified disorders of conjunctiva","text":"Phenotype: Other specified and unspecified disorders of conjunctiva
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.407
N cases: 219
N controls: 345122"}
{"pvalue":0.684,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"conjunctival degenerations and deposits","text":"Phenotype: conjunctival degenerations and deposits
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.684
N cases: 575
N controls: 345122"}
{"pvalue":0.0172,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Conjunctivitis (acute, non atopic)","text":"Phenotype: Conjunctivitis (acute, non atopic)
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0172
N cases: 8907
N controls: 345122"}
{"pvalue":0.0199,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Atopic conjunctivitis","text":"Phenotype: Atopic conjunctivitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0199
N cases: 1211
N controls: 345122"}
{"pvalue":0.0291,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Chronic conjunctivitis","text":"Phenotype: Chronic conjunctivitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0291
N cases: 782
N controls: 345122"}
{"pvalue":0.00005,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Conjunctivitis","text":"Phenotype: Conjunctivitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 4.58e-05
N cases: 28895
N controls: 345122"}
{"pvalue":0.943,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other conjunctival vascular disorders and cysts","text":"Phenotype: Other conjunctival vascular disorders and cysts
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.943
N cases: 585
N controls: 345122"}
{"pvalue":0.253,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Convergence insufficiency and excess","text":"Phenotype: Convergence insufficiency and excess
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.253
N cases: 342
N controls: 361237"}
{"pvalue":0.0454,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Convergent concomitant strabismus","text":"Phenotype: Convergent concomitant strabismus
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0454
N cases: 1690
N controls: 361237"}
{"pvalue":0.947,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Keratoconus","text":"Phenotype: Keratoconus
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.947
N cases: 625
N controls: 357814"}
{"pvalue":0.359,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Corneal degeneration","text":"Phenotype: Corneal degeneration
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.359
N cases: 297
N controls: 357814"}
{"pvalue":0.111,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other and unspecified corneal deformities and disorders","text":"Phenotype: Other and unspecified corneal deformities and disorders
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.111
N cases: 832
N controls: 357814"}
{"pvalue":0.594,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other corneal oedema","text":"Phenotype: Other corneal oedema
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.594
N cases: 164
N controls: 357814"}
{"pvalue":0.0548,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of cornea","text":"Phenotype: Other disorders of cornea
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0548
N cases: 2510
N controls: 357814"}
{"pvalue":0.593,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Corneal scars and opacities","text":"Phenotype: Corneal scars and opacities
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.593
N cases: 616
N controls: 357814"}
{"pvalue":0.177,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Corneal pigmentations and deposits","text":"Phenotype: Corneal pigmentations and deposits
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.177
N cases: 102
N controls: 357814"}
{"pvalue":0.571,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Corneal ulcer","text":"Phenotype: Corneal ulcer
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.571
N cases: 5476
N controls: 357814"}
{"pvalue":0.621,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Colour vision deficiencies","text":"Phenotype: Colour vision deficiencies
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.621
N cases: 109
N controls: 360091"}
{"pvalue":0.534,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Dacryoadenitis","text":"Phenotype: Dacryoadenitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.534
N cases: 198
N controls: 344684"}
{"pvalue":0.639,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Degenerative myopia","text":"Phenotype: Degenerative myopia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.639
N cases: 161
N controls: 361552"}
{"pvalue":0.0805,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Diplopia","text":"Phenotype: Diplopia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0805
N cases: 3700
N controls: 360091"}
{"pvalue":0.419,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other specified and unspecified disorders of lens","text":"Phenotype: Other specified and unspecified disorders of lens
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.419
N cases: 215
N controls: 312864"}
{"pvalue":0.0015,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Divergent concomitant strabismus","text":"Phenotype: Divergent concomitant strabismus
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0015
N cases: 2289
N controls: 361237"}
{"pvalue":0.654,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Ectropion of eyelid","text":"Phenotype: Ectropion of eyelid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.654
N cases: 1059
N controls: 344684"}
{"pvalue":0.691,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Entropion and trichiasis of eyelid","text":"Phenotype: Entropion and trichiasis of eyelid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.691
N cases: 2305
N controls: 344684"}
{"pvalue":0.719,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Epiphora","text":"Phenotype: Epiphora
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.719
N cases: 535
N controls: 344684"}
{"pvalue":0.0355,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Episcleritis","text":"Phenotype: Episcleritis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0355
N cases: 1392
N controls: 357814"}
{"pvalue":0.624,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Exophthalmic conditions","text":"Phenotype: Exophthalmic conditions
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.624
N cases: 283
N controls: 344684"}
{"pvalue":0.829,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other specified and unspecified disorders of eye and adnexa","text":"Phenotype: Other specified and unspecified disorders of eye and adnexa
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.829
N cases: 1074
N controls: 373254"}
{"pvalue":0.398,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of eyelid","text":"Phenotype: Other disorders of eyelid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.398
N cases: 14347
N controls: 344684"}
{"pvalue":0.987,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other disorders affecting eyelid function","text":"Phenotype: Other disorders affecting eyelid function
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.987
N cases: 191
N controls: 344684"}
{"pvalue":0.279,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other inflammation of eyelid","text":"Phenotype: Other inflammation of eyelid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.279
N cases: 3332
N controls: 344684"}
{"pvalue":0.228,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Disorders of eyelid in diseases classified elsewhere","text":"Phenotype: Disorders of eyelid in diseases classified elsewhere
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.228
N cases: 890
N controls: 344684"}
{"pvalue":0.0268,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other specified and unspecified disorders of eyelid","text":"Phenotype: Other specified and unspecified disorders of eyelid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0268
N cases: 318
N controls: 344684"}
{"pvalue":0.975,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of eye and adnexa","text":"Phenotype: Other disorders of eye and adnexa
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.975
N cases: 4023
N controls: 373254"}
{"pvalue":0.00689,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Primary angle-closure glaucoma","text":"Phenotype: Primary angle-closure glaucoma
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00689
N cases: 1199
N controls: 358375"}
{"pvalue":0.596,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other and unspecified glaucoma","text":"Phenotype: Other and unspecified glaucoma
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.596
N cases: 1638
N controls: 358375"}
{"pvalue":0.966,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Glaucoma","text":"Phenotype: Glaucoma
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.966
N cases: 18902
N controls: 358375"}
{"pvalue":0.377,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Juvenile Open Angle Glaucoma","text":"Phenotype: Juvenile Open Angle Glaucoma
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.377
N cases: 151
N controls: 377126"}
{"pvalue":0.467,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Use of antiglaucoma preparations and miotics","text":"Phenotype: Use of antiglaucoma preparations and miotics
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.467
N cases: 2349
N controls: 358375"}
{"pvalue":0.297,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Normotensive glaucoma","text":"Phenotype: Normotensive glaucoma
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.297
N cases: 2085
N controls: 358375"}
{"pvalue":0.55,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Primary open-angle glaucoma, strict","text":"Phenotype: Primary open-angle glaucoma, strict
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.55
N cases: 7756
N controls: 358375"}
{"pvalue":0.149,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Glaucoma, exfoliation","text":"Phenotype: Glaucoma, exfoliation
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.149
N cases: 3125
N controls: 358375"}
{"pvalue":0.661,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Glaucoma secondary to eye inflammation","text":"Phenotype: Glaucoma secondary to eye inflammation
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.661
N cases: 211
N controls: 358375"}
{"pvalue":0.421,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Glaucoma secondary to eye trauma","text":"Phenotype: Glaucoma secondary to eye trauma
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.421
N cases: 166
N controls: 358375"}
{"pvalue":0.246,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Glaucoma suspect","text":"Phenotype: Glaucoma suspect
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.246
N cases: 10758
N controls: 358375"}
{"pvalue":0.81,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Degenerative conditions of globe","text":"Phenotype: Degenerative conditions of globe
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.81
N cases: 151
N controls: 361552"}
{"pvalue":0.987,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Disorders of globe","text":"Phenotype: Disorders of globe
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.987
N cases: 651
N controls: 361552"}
{"pvalue":0.263,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Hereditary retinal dystrophy","text":"Phenotype: Hereditary retinal dystrophy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.263
N cases: 380
N controls: 344569"}
{"pvalue":0.162,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Herpesviral keratitis and keratoconjunctivitis","text":"Phenotype: Herpesviral keratitis and keratoconjunctivitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.162
N cases: 1145
N controls: 357814"}
{"pvalue":0.863,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Heterophoria","text":"Phenotype: Heterophoria
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.863
N cases: 2233
N controls: 361237"}
{"pvalue":0.534,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Hordeolum and other deep inflammation of eyelid","text":"Phenotype: Hordeolum and other deep inflammation of eyelid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.534
N cases: 1320
N controls: 344684"}
{"pvalue":0.578,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Hypermetropia","text":"Phenotype: Hypermetropia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.578
N cases: 1734
N controls: 361237"}
{"pvalue":0.592,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Intermittent heterotropia","text":"Phenotype: Intermittent heterotropia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.592
N cases: 1617
N controls: 361237"}
{"pvalue":0.62,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Internuclear ophthalmoplegia","text":"Phenotype: Internuclear ophthalmoplegia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.62
N cases: 93
N controls: 361237"}
{"pvalue":0.432,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Acute and subacute iridocyclitis","text":"Phenotype: Acute and subacute iridocyclitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.432
N cases: 6166
N controls: 357814"}
{"pvalue":0.0993,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Chronic iridocyclitis","text":"Phenotype: Chronic iridocyclitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0993
N cases: 1401
N controls: 357814"}
{"pvalue":0.429,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Anterior Iridocyclitis","text":"Phenotype: Anterior Iridocyclitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.429
N cases: 6536
N controls: 370741"}
{"pvalue":0.449,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Iridocyclitis","text":"Phenotype: Iridocyclitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.449
N cases: 7306
N controls: 357814"}
{"pvalue":0.675,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Iridocyclitis in diseases classified elsewhere","text":"Phenotype: Iridocyclitis in diseases classified elsewhere
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.675
N cases: 422
N controls: 357814"}
{"pvalue":0.31,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other and unspecified iridocyclitis","text":"Phenotype: Other and unspecified iridocyclitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.31
N cases: 1069
N controls: 357814"}
{"pvalue":0.0571,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other specified and unspecified disorders of iris and ciliary body","text":"Phenotype: Other specified and unspecified disorders of iris and ciliary body
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0571
N cases: 99
N controls: 357814"}
{"pvalue":0.261,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Keratitis","text":"Phenotype: Keratitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.261
N cases: 11611
N controls: 357814"}
{"pvalue":0.459,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Keratitis and keratoconjunctivitis in other diseases classified elsewhere","text":"Phenotype: Keratitis and keratoconjunctivitis in other diseases classified elsewhere
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.459
N cases: 967
N controls: 357814"}
{"pvalue":0.276,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other keratitis","text":"Phenotype: Other keratitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.276
N cases: 3169
N controls: 357814"}
{"pvalue":0.0436,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Hereditary corneal dystrophies","text":"Phenotype: Hereditary corneal dystrophies
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0436
N cases: 725
N controls: 357814"}
{"pvalue":0.763,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Disorders of lacrimal system","text":"Phenotype: Disorders of lacrimal system
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.763
N cases: 13326
N controls: 344684"}
{"pvalue":0.247,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Inflammation of lacrimal passages (acute and unspecified)","text":"Phenotype: Inflammation of lacrimal passages (acute and unspecified)
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.247
N cases: 435
N controls: 344684"}
{"pvalue":0.147,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Inflammation of lacrimal passages (chronic)","text":"Phenotype: Inflammation of lacrimal passages (chronic)
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.147
N cases: 434
N controls: 344684"}
{"pvalue":0.453,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Lagophthalmos","text":"Phenotype: Lagophthalmos
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.453
N cases: 281
N controls: 344684"}
{"pvalue":0.725,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Dislocation of lens","text":"Phenotype: Dislocation of lens
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.725
N cases: 417
N controls: 312864"}
{"pvalue":0.807,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Disorders of eyelid, lacrimal system and orbit","text":"Phenotype: Disorders of eyelid, lacrimal system and orbit
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.807
N cases: 32593
N controls: 344684"}
{"pvalue":0.929,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Degeneration of macula and posterior pole","text":"Phenotype: Degeneration of macula and posterior pole
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.929
N cases: 15137
N controls: 344569"}
{"pvalue":0.89,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Mild or no visual impairment, binocular","text":"Phenotype: Mild or no visual impairment, binocular
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.89
N cases: 120
N controls: 360091"}
{"pvalue":0.606,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Moderate visual impairment, binocular","text":"Phenotype: Moderate visual impairment, binocular
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.606
N cases: 840
N controls: 360091"}
{"pvalue":0.773,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Moderate visual impairment, monocular","text":"Phenotype: Moderate visual impairment, monocular
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.773
N cases: 98
N controls: 360091"}
{"pvalue":0.957,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Myopia","text":"Phenotype: Myopia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.957
N cases: 3534
N controls: 361237"}
{"pvalue":0.43,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Nystagmus and other irregular eye movements","text":"Phenotype: Nystagmus and other irregular eye movements
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.43
N cases: 346
N controls: 373254"}
{"pvalue":0.157,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Disorders of ocular muscles, binocular movement, accommodation and refraction","text":"Phenotype: Disorders of ocular muscles, binocular movement, accommodation and refraction
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.157
N cases: 16040
N controls: 361237"}
{"pvalue":0.621,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Ocular pain","text":"Phenotype: Ocular pain
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.621
N cases: 2121
N controls: 373254"}
{"pvalue":0.535,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Optic atrophy","text":"Phenotype: Optic atrophy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.535
N cases: 430
N controls: 374574"}
{"pvalue":0.0655,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of optic disc","text":"Phenotype: Other disorders of optic disc
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0655
N cases: 292
N controls: 374574"}
{"pvalue":0.181,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Disorders of optic nerve and visual pathways","text":"Phenotype: Disorders of optic nerve and visual pathways
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.181
N cases: 2703
N controls: 374574"}
{"pvalue":0.0483,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Disorders of optic nerve, not elsewhere classified","text":"Phenotype: Disorders of optic nerve, not elsewhere classified
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0483
N cases: 504
N controls: 374574"}
{"pvalue":0.735,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Optic neuritis","text":"Phenotype: Optic neuritis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.735
N cases: 1202
N controls: 374574"}
{"pvalue":0.17,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of optic [2nd] nerve and visual pathways","text":"Phenotype: Other disorders of optic [2nd] nerve and visual pathways
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.17
N cases: 1631
N controls: 374574"}
{"pvalue":0.27,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Disorders of orbit","text":"Phenotype: Disorders of orbit
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.27
N cases: 1199
N controls: 344684"}
{"pvalue":0.809,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Acute inflammation of orbit","text":"Phenotype: Acute inflammation of orbit
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.809
N cases: 167
N controls: 344684"}
{"pvalue":0.252,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other and unspecified disorders of orbit","text":"Phenotype: Other and unspecified disorders of orbit
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.252
N cases: 117
N controls: 344684"}
{"pvalue":0.314,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other endophthalmitis","text":"Phenotype: Other endophthalmitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.314
N cases: 136
N controls: 361552"}
{"pvalue":0.661,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of conjunctiva","text":"Phenotype: Other disorders of conjunctiva
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.661
N cases: 3927
N controls: 345122"}
{"pvalue":0.486,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other disorders of iris and ciliary body","text":"Phenotype: Other disorders of iris and ciliary body
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.486
N cases: 670
N controls: 357814"}
{"pvalue":0.374,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other retinal artery occlusion","text":"Phenotype: Other retinal artery occlusion
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.374
N cases: 569
N controls: 344569"}
{"pvalue":0.715,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Papilloedema, unspecified","text":"Phenotype: Papilloedema, unspecified
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.715
N cases: 545
N controls: 374574"}
{"pvalue":0.043,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Third [oculomotor] nerve palsy","text":"Phenotype: Third [oculomotor] nerve palsy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.043
N cases: 460
N controls: 361237"}
{"pvalue":0.564,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Fourth [trochlear] nerve palsy","text":"Phenotype: Fourth [trochlear] nerve palsy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.564
N cases: 571
N controls: 361237"}
{"pvalue":0.622,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Sixth [abducent] nerve palsy","text":"Phenotype: Sixth [abducent] nerve palsy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.622
N cases: 810
N controls: 361237"}
{"pvalue":0.236,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Paralytic strabismus","text":"Phenotype: Paralytic strabismus
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.236
N cases: 1905
N controls: 361237"}
{"pvalue":0.553,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other or unspecified paralytic strabismus","text":"Phenotype: Other or unspecified paralytic strabismus
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.553
N cases: 177
N controls: 361237"}
{"pvalue":0.547,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Peripheral retinal degeneration","text":"Phenotype: Peripheral retinal degeneration
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.547
N cases: 810
N controls: 344569"}
{"pvalue":0.297,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Presbyopia","text":"Phenotype: Presbyopia
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.297
N cases: 1327
N controls: 361237"}
{"pvalue":0.506,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other proliferative retinopathy","text":"Phenotype: Other proliferative retinopathy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.506
N cases: 122
N controls: 344569"}
{"pvalue":0.189,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Pterygium","text":"Phenotype: Pterygium
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.189
N cases: 718
N controls: 345122"}
{"pvalue":0.278,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Ptosis of eyelid","text":"Phenotype: Ptosis of eyelid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.278
N cases: 2807
N controls: 344684"}
{"pvalue":0.22,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Purulent endophthalmitis","text":"Phenotype: Purulent endophthalmitis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.22
N cases: 140
N controls: 361552"}
{"pvalue":0.946,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Disorders of refraction and accommodation","text":"Phenotype: Disorders of refraction and accommodation
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.946
N cases: 7737
N controls: 361237"}
{"pvalue":0.0704,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Retinal haemorrhage","text":"Phenotype: Retinal haemorrhage
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0704
N cases: 569
N controls: 344569"}
{"pvalue":0.0686,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Retinal breaks without detachment","text":"Phenotype: Retinal breaks without detachment
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0686
N cases: 4390
N controls: 344569"}
{"pvalue":0.557,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Retinal detachment with retinal break","text":"Phenotype: Retinal detachment with retinal break
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.557
N cases: 3712
N controls: 344569"}
{"pvalue":0.154,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Retinal detachments and breaks","text":"Phenotype: Retinal detachments and breaks
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.154
N cases: 11230
N controls: 344569"}
{"pvalue":0.781,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other, unspecified and serous retinal detachments","text":"Phenotype: Other, unspecified and serous retinal detachments
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.781
N cases: 765
N controls: 344569"}
{"pvalue":0.402,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Traction detachment of retina","text":"Phenotype: Traction detachment of retina
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.402
N cases: 223
N controls: 344569"}
{"pvalue":0.438,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other retinal disorders","text":"Phenotype: Other retinal disorders
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.438
N cases: 23610
N controls: 344569"}
{"pvalue":0.0172,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other specified and unspecified retinal disorders","text":"Phenotype: Other specified and unspecified retinal disorders
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0172
N cases: 847
N controls: 344569"}
{"pvalue":0.968,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Separation of retinal layers (serosa)","text":"Phenotype: Separation of retinal layers (serosa)
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.968
N cases: 1068
N controls: 344569"}
{"pvalue":0.421,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Retinal vascular disorders","text":"Phenotype: Retinal vascular disorders
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.421
N cases: 3447
N controls: 344569"}
{"pvalue":0.337,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Retinoschisis and retinal cysts","text":"Phenotype: Retinoschisis and retinal cysts
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.337
N cases: 579
N controls: 344569"}
{"pvalue":0.183,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Diabetic background retinopathy","text":"Phenotype: Diabetic background retinopathy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.183
N cases: 4011
N controls: 344569"}
{"pvalue":0.407,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Severe diabetic background retinopathy","text":"Phenotype: Severe diabetic background retinopathy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.407
N cases: 816
N controls: 344569"}
{"pvalue":0.225,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Diabetic retinopathy","text":"Phenotype: Diabetic retinopathy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.225
N cases: 6818
N controls: 344569"}
{"pvalue":0.15,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other diabetic retinopathy","text":"Phenotype: Other diabetic retinopathy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.15
N cases: 1912
N controls: 344569"}
{"pvalue":0.895,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Proliferative diabetic retinopathy","text":"Phenotype: Proliferative diabetic retinopathy
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.895
N cases: 2468
N controls: 344569"}
{"pvalue":0.487,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Retinopathy of prematurity","text":"Phenotype: Retinopathy of prematurity
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.487
N cases: 87
N controls: 344569"}
{"pvalue":0.5,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Retinal vascular occlusion","text":"Phenotype: Retinal vascular occlusion
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.5
N cases: 3342
N controls: 344569"}
{"pvalue":0.0814,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Retrobulbar neuritis in diseases classified elsewhere","text":"Phenotype: Retrobulbar neuritis in diseases classified elsewhere
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0814
N cases: 95
N controls: 374574"}
{"pvalue":0.834,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Disorders of sclera, cornea, iris and ciliary body","text":"Phenotype: Disorders of sclera, cornea, iris and ciliary body
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.834
N cases: 19463
N controls: 357814"}
{"pvalue":0.607,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Scleritis","text":"Phenotype: Scleritis
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.607
N cases: 290
N controls: 357814"}
{"pvalue":0.675,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Severe visual impairment, binocular","text":"Phenotype: Severe visual impairment, binocular
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.675
N cases: 122
N controls: 360091"}
{"pvalue":0.221,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Severe visual impairment, monocular","text":"Phenotype: Severe visual impairment, monocular
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.221
N cases: 180
N controls: 360091"}
{"pvalue":0.795,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Stenosis and insufficiency of lacrimal passages","text":"Phenotype: Stenosis and insufficiency of lacrimal passages
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.795
N cases: 2653
N controls: 344684"}
{"pvalue":0.0329,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Other specified and unspecified strabismus","text":"Phenotype: Other specified and unspecified strabismus
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0329
N cases: 275
N controls: 361237"}
{"pvalue":0.105,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other strabismus","text":"Phenotype: Other strabismus
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.105
N cases: 7179
N controls: 361237"}
{"pvalue":0.883,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Hyphaema and other vascular disorders of iris and ciliary body","text":"Phenotype: Hyphaema and other vascular disorders of iris and ciliary body
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.883
N cases: 467
N controls: 357814"}
{"pvalue":0.908,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Vertical strabismus","text":"Phenotype: Vertical strabismus
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.908
N cases: 873
N controls: 361237"}
{"pvalue":0.213,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other and unspecified visual disturbances","text":"Phenotype: Other and unspecified visual disturbances
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.213
N cases: 2382
N controls: 360091"}
{"pvalue":0.688,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Visual field defects","text":"Phenotype: Visual field defects
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.688
N cases: 2373
N controls: 360091"}
{"pvalue":0.456,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Blindness or visual impairment, binocular","text":"Phenotype: Blindness or visual impairment, binocular
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.456
N cases: 117
N controls: 360091"}
{"pvalue":0.148,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Visual disturbances","text":"Phenotype: Visual disturbances
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.148
N cases: 15707
N controls: 360091"}
{"pvalue":0.602,"sign":1,"group":"H7: Eye and adnexa diseases","label":"Subjective visual disturbances","text":"Phenotype: Subjective visual disturbances
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.602
N cases: 7313
N controls: 360091"}
{"pvalue":0.538,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Disorders of vitreous body","text":"Phenotype: Disorders of vitreous body
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.538
N cases: 15177
N controls: 361552"}
{"pvalue":0.278,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Crystalline deposits in vitreous body","text":"Phenotype: Crystalline deposits in vitreous body
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.278
N cases: 202
N controls: 361552"}
{"pvalue":0.122,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other vitreous opacities","text":"Phenotype: Other vitreous opacities
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.122
N cases: 993
N controls: 361552"}
{"pvalue":0.797,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Other and unspecified disorders of vitreous body","text":"Phenotype: Other and unspecified disorders of vitreous body
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.797
N cases: 12004
N controls: 361552"}
{"pvalue":0.286,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Xanthelasma of eyelid","text":"Phenotype: Xanthelasma of eyelid
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.286
N cases: 228
N controls: 344684"}
{"pvalue":0.229,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Other abnormal auditory perceptions","text":"Phenotype: Other abnormal auditory perceptions
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.229
N cases: 261
N controls: 331736"}
{"pvalue":0.415,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Benign paroxysmal vertigo","text":"Phenotype: Benign paroxysmal vertigo
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.415
N cases: 8280
N controls: 359094"}
{"pvalue":0.519,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Impacted cerumen","text":"Phenotype: Impacted cerumen
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.519
N cases: 2253
N controls: 367005"}
{"pvalue":0.404,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Cholesteatoma of middle ear","text":"Phenotype: Cholesteatoma of middle ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.404
N cases: 1447
N controls: 352571"}
{"pvalue":0.356,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Chronic suppurative otitis media","text":"Phenotype: Chronic suppurative otitis media
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.356
N cases: 2101
N controls: 352571"}
{"pvalue":0.961,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Discontinuity and dislocation of ear ossicles","text":"Phenotype: Discontinuity and dislocation of ear ossicles
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.961
N cases: 126
N controls: 352571"}
{"pvalue":0.674,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Other disorders of Eustachian tube","text":"Phenotype: Other disorders of Eustachian tube
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.674
N cases: 686
N controls: 352571"}
{"pvalue":0.312,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Eustachian salpingitis and obstruction","text":"Phenotype: Eustachian salpingitis and obstruction
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.312
N cases: 2425
N controls: 352571"}
{"pvalue":0.716,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Abscess of external ear","text":"Phenotype: Abscess of external ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.716
N cases: 375
N controls: 367005"}
{"pvalue":0.89,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Cellulitis of external ear","text":"Phenotype: Cellulitis of external ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.89
N cases: 307
N controls: 367005"}
{"pvalue":0.789,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Cholesteatoma of external ear","text":"Phenotype: Cholesteatoma of external ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.789
N cases: 157
N controls: 367005"}
{"pvalue":0.195,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Disorder of external ear, unspecified","text":"Phenotype: Disorder of external ear, unspecified
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.195
N cases: 770
N controls: 367005"}
{"pvalue":0.39,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Other specified disorders of external ear","text":"Phenotype: Other specified disorders of external ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.39
N cases: 923
N controls: 367005"}
{"pvalue":0.113,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Diseases of external ear","text":"Phenotype: Diseases of external ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.113
N cases: 10272
N controls: 367005"}
{"pvalue":0.546,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Other infective otitis externa","text":"Phenotype: Other infective otitis externa
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.546
N cases: 1621
N controls: 367005"}
{"pvalue":0.2,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Otitis externa, unspecified","text":"Phenotype: Otitis externa, unspecified
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.2
N cases: 2934
N controls: 367005"}
{"pvalue":0.298,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Acute otitis externa, noninfective","text":"Phenotype: Acute otitis externa, noninfective
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.298
N cases: 435
N controls: 367005"}
{"pvalue":0.706,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Other otitis externa (chronic)","text":"Phenotype: Other otitis externa (chronic)
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.706
N cases: 1700
N controls: 367005"}
{"pvalue":0.0274,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Otitis externa","text":"Phenotype: Otitis externa
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0274
N cases: 6547
N controls: 367005"}
{"pvalue":0.569,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Conductive hearing loss, unspecified","text":"Phenotype: Conductive hearing loss, unspecified
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.569
N cases: 2398
N controls: 331736"}
{"pvalue":0.183,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Deaf mutism, not elsewhere classified","text":"Phenotype: Deaf mutism, not elsewhere classified
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.183
N cases: 147
N controls: 331736"}
{"pvalue":0.289,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Sudden idiopathic hearing loss","text":"Phenotype: Sudden idiopathic hearing loss
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.289
N cases: 2848
N controls: 331736"}
{"pvalue":0.101,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Mixed conductive and sensorineural hearing loss","text":"Phenotype: Mixed conductive and sensorineural hearing loss
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.101
N cases: 3581
N controls: 331736"}
{"pvalue":0.604,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Other specified/unspecified hearing loss","text":"Phenotype: Other specified/unspecified hearing loss
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.604
N cases: 2105
N controls: 331736"}
{"pvalue":0.915,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Presbycusis","text":"Phenotype: Presbycusis
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.915
N cases: 4140
N controls: 331736"}
{"pvalue":0.0482,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Sensorineural hearing loss","text":"Phenotype: Sensorineural hearing loss
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0482
N cases: 32487
N controls: 331736"}
{"pvalue":0.789,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Other specified/unspecified diseases of inner ear","text":"Phenotype: Other specified/unspecified diseases of inner ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.789
N cases: 123
N controls: 359094"}
{"pvalue":0.659,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Labyrinthine fistula","text":"Phenotype: Labyrinthine fistula
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.659
N cases: 80
N controls: 359094"}
{"pvalue":0.373,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Labyrinthitis","text":"Phenotype: Labyrinthitis
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.373
N cases: 80
N controls: 359094"}
{"pvalue":0.25,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Acute mastoiditis","text":"Phenotype: Acute mastoiditis
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.25
N cases: 246
N controls: 352571"}
{"pvalue":0.804,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Chronic mastoiditis","text":"Phenotype: Chronic mastoiditis
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.804
N cases: 727
N controls: 352571"}
{"pvalue":0.0115,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Other/unspecified mastoiditis and related conditions","text":"Phenotype: Other/unspecified mastoiditis and related conditions
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0115
N cases: 122
N controls: 352571"}
{"pvalue":0.043,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Suppurative and unspecified otitis media","text":"Phenotype: Suppurative and unspecified otitis media
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.043
N cases: 14406
N controls: 352571"}
{"pvalue":0.636,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Ménière disease","text":"Phenotype: Ménière disease
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.636
N cases: 2746
N controls: 359094"}
{"pvalue":0.209,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Adhesive middle ear disease","text":"Phenotype: Adhesive middle ear disease
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.209
N cases: 444
N controls: 352571"}
{"pvalue":0.0442,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Diseases of middle ear and mastoid","text":"Phenotype: Diseases of middle ear and mastoid
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0442
N cases: 24706
N controls: 352571"}
{"pvalue":0.763,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Acute myringitis","text":"Phenotype: Acute myringitis
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.763
N cases: 167
N controls: 352571"}
{"pvalue":0.976,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Chronic myringitis","text":"Phenotype: Chronic myringitis
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.976
N cases: 106
N controls: 352571"}
{"pvalue":0.826,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Noise effects on inner ear","text":"Phenotype: Noise effects on inner ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.826
N cases: 1050
N controls: 359094"}
{"pvalue":0.0797,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Nonsuppurative otitis media","text":"Phenotype: Nonsuppurative otitis media
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0797
N cases: 8315
N controls: 352571"}
{"pvalue":0.248,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Otalgia","text":"Phenotype: Otalgia
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.248
N cases: 2004
N controls: 331736"}
{"pvalue":0.11,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Other disorders of ear","text":"Phenotype: Other disorders of ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.11
N cases: 45541
N controls: 331736"}
{"pvalue":0.898,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Other hearing loss","text":"Phenotype: Other hearing loss
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.898
N cases: 8833
N controls: 331736"}
{"pvalue":0.241,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Otitis media, unspecified","text":"Phenotype: Otitis media, unspecified
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.241
N cases: 3511
N controls: 352571"}
{"pvalue":0.604,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Otorrhagia","text":"Phenotype: Otorrhagia
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.604
N cases: 152
N controls: 331736"}
{"pvalue":0.511,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Otosclerosis","text":"Phenotype: Otosclerosis
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.511
N cases: 2269
N controls: 359094"}
{"pvalue":0.172,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Perichondritis of external ear","text":"Phenotype: Perichondritis of external ear
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.172
N cases: 431
N controls: 367005"}
{"pvalue":0.863,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Perforation of tympanic membrane","text":"Phenotype: Perforation of tympanic membrane
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.863
N cases: 2814
N controls: 352571"}
{"pvalue":0.29,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Other peripheral vertigo","text":"Phenotype: Other peripheral vertigo
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.29
N cases: 2523
N controls: 359094"}
{"pvalue":0.883,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Recurrent cholesteatoma of postmastoidectomy cavity","text":"Phenotype: Recurrent cholesteatoma of postmastoidectomy cavity
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.883
N cases: 87
N controls: 331736"}
{"pvalue":0.491,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Other disorders following mastoidectomy","text":"Phenotype: Other disorders following mastoidectomy
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.491
N cases: 89
N controls: 331736"}
{"pvalue":0.773,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Postprocedural disorders of ear and mastoid process, not elsewhere classified","text":"Phenotype: Postprocedural disorders of ear and mastoid process, not elsewhere classified
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.773
N cases: 206
N controls: 331736"}
{"pvalue":0.513,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Acquired stenosis of external ear canal","text":"Phenotype: Acquired stenosis of external ear canal
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.513
N cases: 217
N controls: 367005"}
{"pvalue":0.0126,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Acute suppurative otitis media","text":"Phenotype: Acute suppurative otitis media
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0126
N cases: 9850
N controls: 352571"}
{"pvalue":0.035,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Suppurative otitis media, unspecified","text":"Phenotype: Suppurative otitis media, unspecified
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.035
N cases: 722
N controls: 352571"}
{"pvalue":0.858,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Tinnitus","text":"Phenotype: Tinnitus
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.858
N cases: 7175
N controls: 331736"}
{"pvalue":0.168,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Vertigo of central origin","text":"Phenotype: Vertigo of central origin
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.168
N cases: 388
N controls: 359094"}
{"pvalue":0.739,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Disorders of vestibular function (Vertigo)","text":"Phenotype: Disorders of vestibular function (Vertigo)
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.739
N cases: 14918
N controls: 359094"}
{"pvalue":0.306,"sign":-1,"group":"H8: Ear and mastoid process diseases","label":"Vestibular neuronitis","text":"Phenotype: Vestibular neuronitis
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.306
N cases: 2379
N controls: 359094"}
{"pvalue":0.589,"sign":1,"group":"H8: Ear and mastoid process diseases","label":"Other/unspecified disorders of vestibular function","text":"Phenotype: Other/unspecified disorders of vestibular function
Category: H8: Ear and mastoid process diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.589
N cases: 891
N controls: 359094"}
{"pvalue":0.404,"sign":-1,"group":"K11: Digestive system diseases","label":"Inguinal hernia, bilateral","text":"Phenotype: Inguinal hernia, bilateral
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.404
N cases: 2998
N controls: 322586"}
{"pvalue":0.707,"sign":1,"group":"K11: Digestive system diseases","label":"Inguinal hernia, unilateral","text":"Phenotype: Inguinal hernia, unilateral
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.707
N cases: 705
N controls: 322586"}
{"pvalue":0.122,"sign":1,"group":"I9: Circulatory system diseases","label":"Hypotension due to drugs","text":"Phenotype: Hypotension due to drugs
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.122
N cases: 342
N controls: 376935"}
{"pvalue":0.673,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Hypothyroidism, drug reimbursement","text":"Phenotype: Hypothyroidism, drug reimbursement
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.673
N cases: 12040
N controls: 88531"}
{"pvalue":7.64e-08,"sign":-1,"group":"I9: Circulatory system diseases","label":"Abdominal aortic aneurysm (AAA)","text":"Phenotype: Abdominal aortic aneurysm (AAA)
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 7.64e-08
N cases: 3548
N controls: 349539"}
{"pvalue":0.00147,"sign":-1,"group":"I9: Circulatory system diseases","label":"Atrial fibrillation and flutter","text":"Phenotype: Atrial fibrillation and flutter
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00147
N cases: 45766
N controls: 191924"}
{"pvalue":0.0213,"sign":-1,"group":"I9: Circulatory system diseases","label":"Atrial fibrillation and flutter with reimbursement","text":"Phenotype: Atrial fibrillation and flutter with reimbursement
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0213
N cases: 21700
N controls: 191924"}
{"pvalue":0.922,"sign":1,"group":"I9: Circulatory system diseases","label":"Cerebral aneurysm, nonruptured","text":"Phenotype: Cerebral aneurysm, nonruptured
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.922
N cases: 2582
N controls: 342673"}
{"pvalue":0.00019,"sign":-1,"group":"I9: Circulatory system diseases","label":"Angina pectoris","text":"Phenotype: Angina pectoris
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.000191
N cases: 34456
N controls: 313400"}
{"pvalue":0.00001,"sign":-1,"group":"I9: Circulatory system diseases","label":"Coronary angioplasty","text":"Phenotype: Coronary angioplasty
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 1.24e-05
N cases: 14723
N controls: 313400"}
{"pvalue":4e-06,"sign":-1,"group":"I9: Circulatory system diseases","label":"Aortic aneurysm","text":"Phenotype: Aortic aneurysm
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 4e-06
N cases: 7395
N controls: 349539"}
{"pvalue":0.493,"sign":-1,"group":"I9: Circulatory system diseases","label":"Dissection of aorta","text":"Phenotype: Dissection of aorta
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.493
N cases: 881
N controls: 349539"}
{"pvalue":0.868,"sign":-1,"group":"I9: Circulatory system diseases","label":"Arterial embolism and thrombosis","text":"Phenotype: Arterial embolism and thrombosis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.868
N cases: 1735
N controls: 349539"}
{"pvalue":0.712,"sign":1,"group":"I9: Circulatory system diseases","label":"Arterial embolism and thrombosis of lower extremity artery","text":"Phenotype: Arterial embolism and thrombosis of lower extremity artery
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.712
N cases: 985
N controls: 349539"}
{"pvalue":0.754,"sign":-1,"group":"I9: Circulatory system diseases","label":"Other arterial embolism and thrombosis","text":"Phenotype: Other arterial embolism and thrombosis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.754
N cases: 812
N controls: 349539"}
{"pvalue":0.671,"sign":1,"group":"I9: Circulatory system diseases","label":"Other diseases of arteries and capillaries","text":"Phenotype: Other diseases of arteries and capillaries
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.671
N cases: 2679
N controls: 349539"}
{"pvalue":0.00006,"sign":-1,"group":"I9: Circulatory system diseases","label":"Atherosclerosis, excluding cerebral, coronary and PAD","text":"Phenotype: Atherosclerosis, excluding cerebral, coronary and PAD
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 5.56e-05
N cases: 15002
N controls: 349539"}
{"pvalue":0.753,"sign":1,"group":"I9: Circulatory system diseases","label":"AV-block","text":"Phenotype: AV-block
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.753
N cases: 5536
N controls: 286109"}
{"pvalue":0.00001,"sign":-1,"group":"I9: Circulatory system diseases","label":"Coronary artery bypass grafting","text":"Phenotype: Coronary artery bypass grafting
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 1.49e-05
N cases: 10938
N controls: 313400"}
{"pvalue":0.18,"sign":-1,"group":"I9: Circulatory system diseases","label":"Cardiac arrest","text":"Phenotype: Cardiac arrest
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.18
N cases: 2308
N controls: 191924"}
{"pvalue":0.832,"sign":1,"group":"I9: Circulatory system diseases","label":"Cardiomyopathies, Secondary/extrinsic","text":"Phenotype: Cardiomyopathies, Secondary/extrinsic
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.832
N cases: 156
N controls: 286109"}
{"pvalue":0.892,"sign":1,"group":"I9: Circulatory system diseases","label":"Alcoholic cardiomyopathy","text":"Phenotype: Alcoholic cardiomyopathy
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.892
N cases: 124
N controls: 371403"}
{"pvalue":0.621,"sign":-1,"group":"I9: Circulatory system diseases","label":"Cardiomyopathy","text":"Phenotype: Cardiomyopathy
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.621
N cases: 5874
N controls: 286109"}
{"pvalue":0.555,"sign":-1,"group":"I9: Circulatory system diseases","label":"Cardiomyopathy, Hypertrophic obstructive","text":"Phenotype: Cardiomyopathy, Hypertrophic obstructive
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.555
N cases: 519
N controls: 286109"}
{"pvalue":0.679,"sign":1,"group":"I9: Circulatory system diseases","label":"Cardiomyopathy in other diseases","text":"Phenotype: Cardiomyopathy in other diseases
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.679
N cases: 124
N controls: 286109"}
{"pvalue":0.895,"sign":-1,"group":"I9: Circulatory system diseases","label":"Cardiomyopathy, other and unspecified","text":"Phenotype: Cardiomyopathy, other and unspecified
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.895
N cases: 2412
N controls: 286109"}
{"pvalue":0.443,"sign":-1,"group":"I9: Circulatory system diseases","label":"Restrictive cardiomyopathy","text":"Phenotype: Restrictive cardiomyopathy
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.443
N cases: 96
N controls: 371403"}
{"pvalue":0.0653,"sign":-1,"group":"I9: Circulatory system diseases","label":"Calcific aortic valvular stenosis, operated","text":"Phenotype: Calcific aortic valvular stenosis, operated
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0653
N cases: 9153
N controls: 368124"}
{"pvalue":0.135,"sign":-1,"group":"I9: Circulatory system diseases","label":"Cerebral atherosclerosis","text":"Phenotype: Cerebral atherosclerosis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.135
N cases: 322
N controls: 376955"}
{"pvalue":0.832,"sign":1,"group":"I9: Circulatory system diseases","label":"Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere","text":"Phenotype: Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.832
N cases: 1949
N controls: 342673"}
{"pvalue":0.00003,"sign":-1,"group":"I9: Circulatory system diseases","label":"Major coronary heart disease event","text":"Phenotype: Major coronary heart disease event
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 2.86e-05
N cases: 43518
N controls: 333759"}
{"pvalue":0.412,"sign":-1,"group":"I9: Circulatory system diseases","label":"Conduction disorders","text":"Phenotype: Conduction disorders
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.412
N cases: 9949
N controls: 286109"}
{"pvalue":0.00003,"sign":-1,"group":"I9: Circulatory system diseases","label":"Coronary atherosclerosis","text":"Phenotype: Coronary atherosclerosis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 3.46e-05
N cases: 47550
N controls: 313400"}
{"pvalue":0.118,"sign":1,"group":"I9: Circulatory system diseases","label":"Dissection of cerebral arteries, nonruptured","text":"Phenotype: Dissection of cerebral arteries, nonruptured
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.118
N cases: 180
N controls: 342673"}
{"pvalue":0.239,"sign":1,"group":"I9: Circulatory system diseases","label":"Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified","text":"Phenotype: Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.239
N cases: 53156
N controls: 324121"}
{"pvalue":0.0949,"sign":-1,"group":"I9: Circulatory system diseases","label":"Dronedarone medication","text":"Phenotype: Dronedarone medication
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0949
N cases: 743
N controls: 286109"}
{"pvalue":0.574,"sign":1,"group":"I9: Circulatory system diseases","label":"Endocarditis","text":"Phenotype: Endocarditis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.574
N cases: 940
N controls: 286109"}
{"pvalue":0.501,"sign":-1,"group":"I9: Circulatory system diseases","label":"All-cause Heart Failure","text":"Phenotype: All-cause Heart Failure
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.501
N cases: 26872
N controls: 349361"}
{"pvalue":0.439,"sign":-1,"group":"I9: Circulatory system diseases","label":"Heart failure,strict (more control exclusions)","text":"Phenotype: Heart failure,strict (more control exclusions)
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.439
N cases: 27304
N controls: 328105"}
{"pvalue":0.438,"sign":-1,"group":"I9: Circulatory system diseases","label":"Heart failure,strict","text":"Phenotype: Heart failure,strict
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.438
N cases: 27304
N controls: 349973"}
{"pvalue":0.529,"sign":-1,"group":"I9: Circulatory system diseases","label":"Hypertensive encephalopathy","text":"Phenotype: Hypertensive encephalopathy
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.529
N cases: 96
N controls: 342673"}
{"pvalue":0.266,"sign":-1,"group":"I9: Circulatory system diseases","label":"Hypertrophic cardiomyopathy","text":"Phenotype: Hypertrophic cardiomyopathy
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.266
N cases: 1044
N controls: 376233"}
{"pvalue":0.203,"sign":1,"group":"I9: Circulatory system diseases","label":"Hypotension","text":"Phenotype: Hypotension
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.203
N cases: 4432
N controls: 371886"}
{"pvalue":0.18,"sign":1,"group":"I9: Circulatory system diseases","label":"Secondary hypertension","text":"Phenotype: Secondary hypertension
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.18
N cases: 2597
N controls: 191924"}
{"pvalue":0.783,"sign":1,"group":"I9: Circulatory system diseases","label":"Hypertension, essential","text":"Phenotype: Hypertension, essential
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.783
N cases: 92462
N controls: 265626"}
{"pvalue":0.943,"sign":1,"group":"I9: Circulatory system diseases","label":"Hypertension","text":"Phenotype: Hypertension
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.943
N cases: 111581
N controls: 265626"}
{"pvalue":0.597,"sign":1,"group":"I9: Circulatory system diseases","label":"Hypertensive Heart Disease","text":"Phenotype: Hypertensive Heart Disease
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.597
N cases: 8387
N controls: 265626"}
{"pvalue":0.0973,"sign":1,"group":"I9: Circulatory system diseases","label":"Hypertension, Pulmonary Arterial","text":"Phenotype: Hypertension, Pulmonary Arterial
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0973
N cases: 234
N controls: 265626"}
{"pvalue":0.44,"sign":-1,"group":"I9: Circulatory system diseases","label":"Hypertensive Renal Disease","text":"Phenotype: Hypertensive Renal Disease
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.44
N cases: 1022
N controls: 265626"}
{"pvalue":0.83,"sign":-1,"group":"I9: Circulatory system diseases","label":"Intracerebral haemmorrhage","text":"Phenotype: Intracerebral haemmorrhage
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.83
N cases: 3749
N controls: 339914"}
{"pvalue":0.00001,"sign":-1,"group":"I9: Circulatory system diseases","label":"Ischaemic heart disease, wide definition","text":"Phenotype: Ischaemic heart disease, wide definition
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 1.4e-05
N cases: 63744
N controls: 313533"}
{"pvalue":0.546,"sign":1,"group":"I9: Circulatory system diseases","label":"Nontraumatic intracranial haemmorrhage","text":"Phenotype: Nontraumatic intracranial haemmorrhage
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.546
N cases: 6530
N controls: 342673"}
{"pvalue":0.00467,"sign":-1,"group":"I9: Circulatory system diseases","label":"Death due to cardiac causes","text":"Phenotype: Death due to cardiac causes
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00467
N cases: 19295
N controls: 357982"}
{"pvalue":0.223,"sign":-1,"group":"I9: Circulatory system diseases","label":"Left bundle-branch block","text":"Phenotype: Left bundle-branch block
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.223
N cases: 1918
N controls: 286109"}
{"pvalue":0.316,"sign":1,"group":"I9: Circulatory system diseases","label":"Nonspecific lymphadenitis","text":"Phenotype: Nonspecific lymphadenitis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.316
N cases: 1808
N controls: 324121"}
{"pvalue":0.75,"sign":-1,"group":"I9: Circulatory system diseases","label":"Other noninfective disorders of lymphatic vessels and lymph nodes","text":"Phenotype: Other noninfective disorders of lymphatic vessels and lymph nodes
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.75
N cases: 901
N controls: 324121"}
{"pvalue":0.0334,"sign":1,"group":"I9: Circulatory system diseases","label":"Complications following myocardial infarction","text":"Phenotype: Complications following myocardial infarction
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0334
N cases: 226
N controls: 313400"}
{"pvalue":0.00158,"sign":-1,"group":"I9: Circulatory system diseases","label":"Myocardial infarction, strict","text":"Phenotype: Myocardial infarction, strict
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00158
N cases: 24185
N controls: 313400"}
{"pvalue":0.22,"sign":1,"group":"I9: Circulatory system diseases","label":"Myocarditis","text":"Phenotype: Myocarditis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.22
N cases: 1521
N controls: 191924"}
{"pvalue":0.488,"sign":-1,"group":"I9: Circulatory system diseases","label":"Non-ischemic cardiomyopathy","text":"Phenotype: Non-ischemic cardiomyopathy
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.488
N cases: 9926
N controls: 303607"}
{"pvalue":0.807,"sign":1,"group":"I9: Circulatory system diseases","label":"Nonischemic cardiomyopathy","text":"Phenotype: Nonischemic cardiomyopathy
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.807
N cases: 1639
N controls: 311340"}
{"pvalue":0.256,"sign":-1,"group":"I9: Circulatory system diseases","label":"Non-rheumatic valve diseases","text":"Phenotype: Non-rheumatic valve diseases
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.256
N cases: 20772
N controls: 286109"}
{"pvalue":0.649,"sign":-1,"group":"I9: Circulatory system diseases","label":"Other aneurysm","text":"Phenotype: Other aneurysm
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.649
N cases: 1530
N controls: 349539"}
{"pvalue":0.677,"sign":1,"group":"I9: Circulatory system diseases","label":"Other arrhythmias","text":"Phenotype: Other arrhythmias
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.677
N cases: 28079
N controls: 286109"}
{"pvalue":0.479,"sign":-1,"group":"I9: Circulatory system diseases","label":"Other or ill-defined heart diseases","text":"Phenotype: Other or ill-defined heart diseases
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.479
N cases: 1524
N controls: 286109"}
{"pvalue":0.514,"sign":-1,"group":"I9: Circulatory system diseases","label":"Other intracranial haemorrhages","text":"Phenotype: Other intracranial haemorrhages
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.514
N cases: 768
N controls: 342673"}
{"pvalue":0.179,"sign":-1,"group":"I9: Circulatory system diseases","label":"Other other unspecified disorders of the circulatory system","text":"Phenotype: Other other unspecified disorders of the circulatory system
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.179
N cases: 1002
N controls: 371886"}
{"pvalue":0.685,"sign":1,"group":"I9: Circulatory system diseases","label":"Other peripheral vascular diseases","text":"Phenotype: Other peripheral vascular diseases
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.685
N cases: 2230
N controls: 349539"}
{"pvalue":0.177,"sign":1,"group":"I9: Circulatory system diseases","label":"Paroxysmal tachycardia","text":"Phenotype: Paroxysmal tachycardia
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.177
N cases: 9604
N controls: 191924"}
{"pvalue":0.114,"sign":1,"group":"I9: Circulatory system diseases","label":"Other diseases of pericardium","text":"Phenotype: Other diseases of pericardium
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.114
N cases: 1135
N controls: 286109"}
{"pvalue":0.0395,"sign":1,"group":"I9: Circulatory system diseases","label":"Pericarditis","text":"Phenotype: Pericarditis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0395
N cases: 979
N controls: 286109"}
{"pvalue":0.886,"sign":1,"group":"I9: Circulatory system diseases","label":"DVT of lower extremities","text":"Phenotype: DVT of lower extremities
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.886
N cases: 9109
N controls: 324121"}
{"pvalue":0.00046,"sign":1,"group":"I9: Circulatory system diseases","label":"Phlebitis and thrombophlebitis (not including DVT)","text":"Phenotype: Phlebitis and thrombophlebitis (not including DVT)
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.000465
N cases: 7037
N controls: 324121"}
{"pvalue":0.00719,"sign":-1,"group":"I9: Circulatory system diseases","label":"Status post-ami","text":"Phenotype: Status post-ami
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00719
N cases: 3030
N controls: 313400"}
{"pvalue":0.0938,"sign":1,"group":"I9: Circulatory system diseases","label":"Progressive vascular leukoencephalopathy","text":"Phenotype: Progressive vascular leukoencephalopathy
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0938
N cases: 673
N controls: 342673"}
{"pvalue":0.961,"sign":-1,"group":"I9: Circulatory system diseases","label":"Pulmonary embolism","text":"Phenotype: Pulmonary embolism
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.961
N cases: 9243
N controls: 367108"}
{"pvalue":0.197,"sign":1,"group":"I9: Circulatory system diseases","label":"Portal vein thrombosis","text":"Phenotype: Portal vein thrombosis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.197
N cases: 360
N controls: 324121"}
{"pvalue":0.557,"sign":-1,"group":"I9: Circulatory system diseases","label":"Right bundle-branch block","text":"Phenotype: Right bundle-branch block
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.557
N cases: 954
N controls: 286109"}
{"pvalue":2.87e-07,"sign":-1,"group":"I9: Circulatory system diseases","label":"Coronary revascularization (ANGIO or CABG)","text":"Phenotype: Coronary revascularization (ANGIO or CABG)
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 2.87e-07
N cases: 23139
N controls: 313400"}
{"pvalue":0.0686,"sign":1,"group":"I9: Circulatory system diseases","label":"Rheumatic fever incl heart disease","text":"Phenotype: Rheumatic fever incl heart disease
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0686
N cases: 976
N controls: 376301"}
{"pvalue":0.578,"sign":1,"group":"I9: Circulatory system diseases","label":"Rheumatic fever with heart involvement","text":"Phenotype: Rheumatic fever with heart involvement
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.578
N cases: 138
N controls: 376301"}
{"pvalue":0.174,"sign":1,"group":"I9: Circulatory system diseases","label":"Rheumatic fever without mention of heart involvement","text":"Phenotype: Rheumatic fever without mention of heart involvement
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.174
N cases: 97
N controls: 377180"}
{"pvalue":0.0148,"sign":1,"group":"I9: Circulatory system diseases","label":"Rheumatic valve diseases","text":"Phenotype: Rheumatic valve diseases
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0148
N cases: 703
N controls: 376301"}
{"pvalue":0.83,"sign":1,"group":"I9: Circulatory system diseases","label":"Aneurysms, operations, SAH","text":"Phenotype: Aneurysms, operations, SAH
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.83
N cases: 5342
N controls: 342673"}
{"pvalue":0.444,"sign":1,"group":"I9: Circulatory system diseases","label":"Subarachnoid haemmorrhage","text":"Phenotype: Subarachnoid haemmorrhage
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.444
N cases: 3289
N controls: 339922"}
{"pvalue":0.791,"sign":1,"group":"I9: Circulatory system diseases","label":"Secondary right heart disease","text":"Phenotype: Secondary right heart disease
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.791
N cases: 1068
N controls: 367108"}
{"pvalue":0.643,"sign":-1,"group":"I9: Circulatory system diseases","label":"Sequelae of cerebrovascular disease","text":"Phenotype: Sequelae of cerebrovascular disease
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.643
N cases: 11408
N controls: 342673"}
{"pvalue":0.27,"sign":-1,"group":"I9: Circulatory system diseases","label":"Occlusion and stenosis of arteries, not leading to stroke","text":"Phenotype: Occlusion and stenosis of arteries, not leading to stroke
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.27
N cases: 406
N controls: 342673"}
{"pvalue":0.123,"sign":-1,"group":"I9: Circulatory system diseases","label":"Embolic stroke","text":"Phenotype: Embolic stroke
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.123
N cases: 1373
N controls: 342673"}
{"pvalue":0.0115,"sign":-1,"group":"I9: Circulatory system diseases","label":"Embolic stroke with flimmer","text":"Phenotype: Embolic stroke with flimmer
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0115
N cases: 679
N controls: 331511"}
{"pvalue":0.119,"sign":-1,"group":"I9: Circulatory system diseases","label":"Stroke, excluding SAH","text":"Phenotype: Stroke, excluding SAH
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.119
N cases: 25398
N controls: 339920"}
{"pvalue":0.0244,"sign":-1,"group":"I9: Circulatory system diseases","label":"Thoracic aortic aneurysm","text":"Phenotype: Thoracic aortic aneurysm
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0244
N cases: 3510
N controls: 349539"}
{"pvalue":0.0947,"sign":1,"group":"I9: Circulatory system diseases","label":"Thromboangiitis obliterans","text":"Phenotype: Thromboangiitis obliterans
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0947
N cases: 108
N controls: 349539"}
{"pvalue":0.909,"sign":1,"group":"I9: Circulatory system diseases","label":"Nonpyogenic thrombosis of intracranial venous system","text":"Phenotype: Nonpyogenic thrombosis of intracranial venous system
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.909
N cases: 231
N controls: 342673"}
{"pvalue":0.653,"sign":1,"group":"I9: Circulatory system diseases","label":"Other embolism and thrombosis","text":"Phenotype: Other embolism and thrombosis
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.653
N cases: 3861
N controls: 324121"}
{"pvalue":0.732,"sign":-1,"group":"I9: Circulatory system diseases","label":"Transient ischemic attack","text":"Phenotype: Transient ischemic attack
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.732
N cases: 18398
N controls: 342294"}
{"pvalue":0.0215,"sign":-1,"group":"I9: Circulatory system diseases","label":"Unstable angina pectoris","text":"Phenotype: Unstable angina pectoris
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0215
N cases: 13304
N controls: 333375"}
{"pvalue":0.557,"sign":1,"group":"I9: Circulatory system diseases","label":"Varicose veins","text":"Phenotype: Varicose veins
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.557
N cases: 29539
N controls: 324121"}
{"pvalue":0.524,"sign":1,"group":"I9: Circulatory system diseases","label":"Oesophageal varices","text":"Phenotype: Oesophageal varices
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.524
N cases: 1017
N controls: 324121"}
{"pvalue":0.801,"sign":-1,"group":"I9: Circulatory system diseases","label":"Varicose veins of other sites","text":"Phenotype: Varicose veins of other sites
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.801
N cases: 1866
N controls: 324121"}
{"pvalue":0.162,"sign":1,"group":"I9: Circulatory system diseases","label":"Vascular diseases of the intestine","text":"Phenotype: Vascular diseases of the intestine
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.162
N cases: 966
N controls: 349539"}
{"pvalue":0.437,"sign":-1,"group":"I9: Circulatory system diseases","label":"Vascular syndromes of brain in cerebrovascular disorders","text":"Phenotype: Vascular syndromes of brain in cerebrovascular disorders
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.437
N cases: 1180
N controls: 359161"}
{"pvalue":0.119,"sign":-1,"group":"I9: Circulatory system diseases","label":"Other disorders of veins","text":"Phenotype: Other disorders of veins
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.119
N cases: 12630
N controls: 324121"}
{"pvalue":0.252,"sign":-1,"group":"I9: Circulatory system diseases","label":"Valvular heart disease excluding rheumatic fever","text":"Phenotype: Valvular heart disease excluding rheumatic fever
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.252
N cases: 20929
N controls: 286109"}
{"pvalue":0.374,"sign":1,"group":"I9: Circulatory system diseases","label":"Venous thromboembolism","text":"Phenotype: Venous thromboembolism
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.374
N cases: 19372
N controls: 357905"}
{"pvalue":0.844,"sign":1,"group":"N14: Genitourinary system diseases","label":"Interstitial cystitis (chronic), drug-induced","text":"Phenotype: Interstitial cystitis (chronic), drug-induced
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.844
N cases: 87
N controls: 377190"}
{"pvalue":0.182,"sign":-1,"group":"J10: Respiratory system diseases","label":"Abscess of lung","text":"Phenotype: Abscess of lung
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.182
N cases: 390
N controls: 375800"}
{"pvalue":0.478,"sign":-1,"group":"J10: Respiratory system diseases","label":"Unspecified acute lower respiratory infection","text":"Phenotype: Unspecified acute lower respiratory infection
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.478
N cases: 4616
N controls: 356404"}
{"pvalue":0.186,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute upper respiratory infections of multiple and unspecified sites","text":"Phenotype: Acute upper respiratory infections of multiple and unspecified sites
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.186
N cases: 36445
N controls: 308166"}
{"pvalue":0.253,"sign":-1,"group":"J10: Respiratory system diseases","label":"Adult respiratory distress syndrome","text":"Phenotype: Adult respiratory distress syndrome
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.253
N cases: 328
N controls: 372077"}
{"pvalue":0.822,"sign":-1,"group":"J10: Respiratory system diseases","label":"Pneumoconiosis due to asbestos and other mineral fibres","text":"Phenotype: Pneumoconiosis due to asbestos and other mineral fibres
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.822
N cases: 610
N controls: 372962"}
{"pvalue":0.00111,"sign":1,"group":"J10: Respiratory system diseases","label":"Asthma/COPD (KELA code 203)","text":"Phenotype: Asthma/COPD (KELA code 203)
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00111
N cases: 41495
N controls: 311286"}
{"pvalue":0.00015,"sign":1,"group":"J10: Respiratory system diseases","label":"Asthma (more control exclusions)","text":"Phenotype: Asthma (more control exclusions)
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.000153
N cases: 42163
N controls: 202399"}
{"pvalue":0.00024,"sign":1,"group":"J10: Respiratory system diseases","label":"Asthma (only as main-diagnosis) (more control exclusions)","text":"Phenotype: Asthma (only as main-diagnosis) (more control exclusions)
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.000236
N cases: 34343
N controls: 202399"}
{"pvalue":0.134,"sign":1,"group":"J10: Respiratory system diseases","label":"Bronchitis, not specified as acute or chronic","text":"Phenotype: Bronchitis, not specified as acute or chronic
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.134
N cases: 2816
N controls: 311286"}
{"pvalue":0.772,"sign":-1,"group":"J10: Respiratory system diseases","label":"Bronchiectasis","text":"Phenotype: Bronchiectasis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.772
N cases: 2188
N controls: 311286"}
{"pvalue":0.0968,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute bronchiolitis","text":"Phenotype: Acute bronchiolitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0968
N cases: 1953
N controls: 356404"}
{"pvalue":0.475,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute bronchitis","text":"Phenotype: Acute bronchitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.475
N cases: 15393
N controls: 356404"}
{"pvalue":0.155,"sign":1,"group":"J10: Respiratory system diseases","label":"Unspecified chronic bronchitis","text":"Phenotype: Unspecified chronic bronchitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.155
N cases: 1150
N controls: 311286"}
{"pvalue":0.0102,"sign":1,"group":"J10: Respiratory system diseases","label":"Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours","text":"Phenotype: Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0102
N cases: 233
N controls: 372962"}
{"pvalue":0.311,"sign":1,"group":"J10: Respiratory system diseases","label":"Chronic laryngitis and laryngotracheitis","text":"Phenotype: Chronic laryngitis and laryngotracheitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.311
N cases: 4319
N controls: 283342"}
{"pvalue":0.843,"sign":1,"group":"J10: Respiratory system diseases","label":"Chronic rhinitis, nasopharyngitis and pharyngitis","text":"Phenotype: Chronic rhinitis, nasopharyngitis and pharyngitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.843
N cases: 10868
N controls: 283342"}
{"pvalue":0.0815,"sign":1,"group":"J10: Respiratory system diseases","label":"Chronic sinusitis","text":"Phenotype: Chronic sinusitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0815
N cases: 16395
N controls: 283342"}
{"pvalue":0.00015,"sign":1,"group":"J10: Respiratory system diseases","label":"Chronic diseases of tonsils and adenoids","text":"Phenotype: Chronic diseases of tonsils and adenoids
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.000147
N cases: 43325
N controls: 283342"}
{"pvalue":0.81,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute nasopharyngitis(common cold)","text":"Phenotype: Acute nasopharyngitis(common cold)
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.81
N cases: 3956
N controls: 308166"}
{"pvalue":0.159,"sign":1,"group":"J10: Respiratory system diseases","label":"COPD","text":"Phenotype: COPD
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.159
N cases: 18266
N controls: 311286"}
{"pvalue":0.335,"sign":1,"group":"J10: Respiratory system diseases","label":"Emphysema","text":"Phenotype: Emphysema
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.335
N cases: 1885
N controls: 311286"}
{"pvalue":0.51,"sign":-1,"group":"J10: Respiratory system diseases","label":"Acute epiglottitis","text":"Phenotype: Acute epiglottitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.51
N cases: 418
N controls: 308166"}
{"pvalue":0.554,"sign":1,"group":"J10: Respiratory system diseases","label":"Lung diseases due to external agents","text":"Phenotype: Lung diseases due to external agents
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.554
N cases: 4315
N controls: 372962"}
{"pvalue":0.118,"sign":-1,"group":"J10: Respiratory system diseases","label":"Hypersensitivity pneumonitis due to organic dust","text":"Phenotype: Hypersensitivity pneumonitis due to organic dust
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.118
N cases: 446
N controls: 372962"}
{"pvalue":0.0655,"sign":-1,"group":"J10: Respiratory system diseases","label":"All influenza","text":"Phenotype: All influenza
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0655
N cases: 8555
N controls: 314673"}
{"pvalue":0.34,"sign":1,"group":"J10: Respiratory system diseases","label":"Influenza and pneumonia","text":"Phenotype: Influenza and pneumonia
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.34
N cases: 62604
N controls: 314673"}
{"pvalue":0.729,"sign":-1,"group":"J10: Respiratory system diseases","label":"Pneumoconiosis due to other inorganic dusts","text":"Phenotype: Pneumoconiosis due to other inorganic dusts
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.729
N cases: 112
N controls: 372962"}
{"pvalue":0.00847,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute laryngitis and tracheitis","text":"Phenotype: Acute laryngitis and tracheitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00847
N cases: 4158
N controls: 308166"}
{"pvalue":0.00008,"sign":1,"group":"J10: Respiratory system diseases","label":"Chronic lower respiratory diseases","text":"Phenotype: Chronic lower respiratory diseases
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 8.37e-05
N cases: 65991
N controls: 311286"}
{"pvalue":0.302,"sign":1,"group":"J10: Respiratory system diseases","label":"Other acute lower respiratory infections","text":"Phenotype: Other acute lower respiratory infections
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.302
N cases: 20873
N controls: 356404"}
{"pvalue":0.224,"sign":1,"group":"J10: Respiratory system diseases","label":"Nasal polyp","text":"Phenotype: Nasal polyp
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.224
N cases: 6255
N controls: 283342"}
{"pvalue":0.026,"sign":-1,"group":"J10: Respiratory system diseases","label":"Suppurative and necrotic conditions of lower respiratory tract","text":"Phenotype: Suppurative and necrotic conditions of lower respiratory tract
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.026
N cases: 1477
N controls: 375800"}
{"pvalue":0.00083,"sign":-1,"group":"J10: Respiratory system diseases","label":"Peritonsillar abscess","text":"Phenotype: Peritonsillar abscess
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.000834
N cases: 7510
N controls: 283342"}
{"pvalue":0.719,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute pharyngitis","text":"Phenotype: Acute pharyngitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.719
N cases: 4747
N controls: 308166"}
{"pvalue":0.0178,"sign":1,"group":"J10: Respiratory system diseases","label":"Other diseases of pleura","text":"Phenotype: Other diseases of pleura
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0178
N cases: 15441
N controls: 361836"}
{"pvalue":0.0332,"sign":1,"group":"J10: Respiratory system diseases","label":"Pleural effusion","text":"Phenotype: Pleural effusion
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0332
N cases: 4513
N controls: 361836"}
{"pvalue":0.00759,"sign":1,"group":"J10: Respiratory system diseases","label":"Other pleural conditions","text":"Phenotype: Other pleural conditions
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00759
N cases: 2985
N controls: 361836"}
{"pvalue":0.42,"sign":1,"group":"J10: Respiratory system diseases","label":"Pleural plaque","text":"Phenotype: Pleural plaque
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.42
N cases: 2819
N controls: 361836"}
{"pvalue":0.0197,"sign":1,"group":"J10: Respiratory system diseases","label":"Bacterial pneumoniae","text":"Phenotype: Bacterial pneumoniae
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0197
N cases: 16244
N controls: 314673"}
{"pvalue":0.0174,"sign":1,"group":"J10: Respiratory system diseases","label":"Pneumonia due to Haemophilus influenzae","text":"Phenotype: Pneumonia due to Haemophilus influenzae
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0174
N cases: 87
N controls: 314673"}
{"pvalue":0.0629,"sign":1,"group":"J10: Respiratory system diseases","label":"All pneumoniae","text":"Phenotype: All pneumoniae
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0629
N cases: 58174
N controls: 319103"}
{"pvalue":0.676,"sign":1,"group":"J10: Respiratory system diseases","label":"Pneumonitis due to solids and liquids","text":"Phenotype: Pneumonitis due to solids and liquids
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.676
N cases: 2326
N controls: 372962"}
{"pvalue":0.153,"sign":-1,"group":"J10: Respiratory system diseases","label":"Pneumonia due to other infectious organisms, not elsewhere classified","text":"Phenotype: Pneumonia due to other infectious organisms, not elsewhere classified
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.153
N cases: 830
N controls: 314673"}
{"pvalue":0.605,"sign":1,"group":"J10: Respiratory system diseases","label":"Pneumonia due to Streptococcus pneumoniae","text":"Phenotype: Pneumonia due to Streptococcus pneumoniae
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.605
N cases: 1245
N controls: 314673"}
{"pvalue":0.795,"sign":-1,"group":"J10: Respiratory system diseases","label":"Pneumothorax","text":"Phenotype: Pneumothorax
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.795
N cases: 1999
N controls: 361836"}
{"pvalue":0.129,"sign":1,"group":"J10: Respiratory system diseases","label":"Pulmonary eosinophilia, not elsewhere classified","text":"Phenotype: Pulmonary eosinophilia, not elsewhere classified
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.129
N cases: 324
N controls: 372077"}
{"pvalue":0.716,"sign":-1,"group":"J10: Respiratory system diseases","label":"Pulmonary oedema","text":"Phenotype: Pulmonary oedema
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.716
N cases: 477
N controls: 372077"}
{"pvalue":0.011,"sign":-1,"group":"J10: Respiratory system diseases","label":"Pyothorax","text":"Phenotype: Pyothorax
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.011
N cases: 1120
N controls: 375800"}
{"pvalue":0.67,"sign":1,"group":"J10: Respiratory system diseases","label":"Respiratory conditions due to other external agents","text":"Phenotype: Respiratory conditions due to other external agents
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.67
N cases: 510
N controls: 372962"}
{"pvalue":0.489,"sign":1,"group":"J10: Respiratory system diseases","label":"Other diseases of the respiratory system","text":"Phenotype: Other diseases of the respiratory system
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.489
N cases: 6381
N controls: 370896"}
{"pvalue":0.541,"sign":1,"group":"J10: Respiratory system diseases","label":"Deviated nasal septum","text":"Phenotype: Deviated nasal septum
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.541
N cases: 11680
N controls: 283342"}
{"pvalue":0.194,"sign":1,"group":"J10: Respiratory system diseases","label":"Pneumoconiosis due to dust containing silica","text":"Phenotype: Pneumoconiosis due to dust containing silica
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.194
N cases: 92
N controls: 372962"}
{"pvalue":0.208,"sign":-1,"group":"J10: Respiratory system diseases","label":"Simple and mucopurulent chronic bronchitis","text":"Phenotype: Simple and mucopurulent chronic bronchitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.208
N cases: 1299
N controls: 311286"}
{"pvalue":0.325,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute sinusitis","text":"Phenotype: Acute sinusitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.325
N cases: 20520
N controls: 308166"}
{"pvalue":0.108,"sign":1,"group":"J10: Respiratory system diseases","label":"Tonsillectomy","text":"Phenotype: Tonsillectomy
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.108
N cases: 27449
N controls: 349828"}
{"pvalue":0.164,"sign":-1,"group":"J10: Respiratory system diseases","label":"Other and unspecified tonsillitis","text":"Phenotype: Other and unspecified tonsillitis
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.164
N cases: 13190
N controls: 308166"}
{"pvalue":0.00339,"sign":1,"group":"J10: Respiratory system diseases","label":"Other diseases of upper respiratory tract","text":"Phenotype: Other diseases of upper respiratory tract
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00339
N cases: 93935
N controls: 283342"}
{"pvalue":0.334,"sign":1,"group":"J10: Respiratory system diseases","label":"Acute upper respiratory infections","text":"Phenotype: Acute upper respiratory infections
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.334
N cases: 69111
N controls: 308166"}
{"pvalue":0.281,"sign":1,"group":"J10: Respiratory system diseases","label":"Viral pneumonia","text":"Phenotype: Viral pneumonia
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.281
N cases: 3394
N controls: 314673"}
{"pvalue":0.141,"sign":1,"group":"J10: Respiratory system diseases","label":"Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified","text":"Phenotype: Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified
Category: J10: Respiratory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.141
N cases: 19530
N controls: 283342"}
{"pvalue":0.895,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Pain in joint","text":"Phenotype: Pain in joint
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.895
N cases: 27688
N controls: 205355"}
{"pvalue":0.453,"sign":1,"group":"K11: Digestive system diseases","label":"Abrasion of teeth","text":"Phenotype: Abrasion of teeth
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.453
N cases: 149
N controls: 259234"}
{"pvalue":0.463,"sign":1,"group":"K11: Digestive system diseases","label":"Abscess of anal and rectal regions","text":"Phenotype: Abscess of anal and rectal regions
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.463
N cases: 2595
N controls: 301931"}
{"pvalue":0.204,"sign":1,"group":"K11: Digestive system diseases","label":"Achalasia of cardia","text":"Phenotype: Achalasia of cardia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.204
N cases: 506
N controls: 320387"}
{"pvalue":0.896,"sign":-1,"group":"K11: Digestive system diseases","label":"Acute gastritis","text":"Phenotype: Acute gastritis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.896
N cases: 2370
N controls: 320387"}
{"pvalue":0.107,"sign":1,"group":"K11: Digestive system diseases","label":"Acute pancreatitis","text":"Phenotype: Acute pancreatitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.107
N cases: 6223
N controls: 330903"}
{"pvalue":0.0409,"sign":1,"group":"K11: Digestive system diseases","label":"Intestinal adhesions without obstruction","text":"Phenotype: Intestinal adhesions without obstruction
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0409
N cases: 2370
N controls: 301931"}
{"pvalue":0.0261,"sign":1,"group":"K11: Digestive system diseases","label":"Alcoholic gastritis","text":"Phenotype: Alcoholic gastritis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0261
N cases: 430
N controls: 320387"}
{"pvalue":0.768,"sign":1,"group":"K11: Digestive system diseases","label":"Alcoholic liver disease","text":"Phenotype: Alcoholic liver disease
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.768
N cases: 2761
N controls: 366450"}
{"pvalue":0.0218,"sign":-1,"group":"K11: Digestive system diseases","label":"Anomalies of dental arch relationship, including avohilmo","text":"Phenotype: Anomalies of dental arch relationship, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0218
N cases: 6260
N controls: 371017"}
{"pvalue":0.632,"sign":-1,"group":"K11: Digestive system diseases","label":"Recurring oral aphthae","text":"Phenotype: Recurring oral aphthae
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.632
N cases: 1221
N controls: 376056"}
{"pvalue":0.184,"sign":-1,"group":"K11: Digestive system diseases","label":"Recurring oral aphthae, including avohilmo","text":"Phenotype: Recurring oral aphthae, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.184
N cases: 3577
N controls: 373700"}
{"pvalue":0.069,"sign":1,"group":"K11: Digestive system diseases","label":"Acute appendicitis","text":"Phenotype: Acute appendicitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.069
N cases: 28745
N controls: 346283"}
{"pvalue":0.225,"sign":1,"group":"K11: Digestive system diseases","label":"Appendectomy","text":"Phenotype: Appendectomy
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.225
N cases: 26013
N controls: 351264"}
{"pvalue":0.773,"sign":-1,"group":"K11: Digestive system diseases","label":"Other appendicitis","text":"Phenotype: Other appendicitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.773
N cases: 2545
N controls: 346283"}
{"pvalue":0.831,"sign":1,"group":"K11: Digestive system diseases","label":"Asymmetry of jaw","text":"Phenotype: Asymmetry of jaw
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.831
N cases: 369
N controls: 376908"}
{"pvalue":0.251,"sign":1,"group":"K11: Digestive system diseases","label":"Excessive attrition of teeth","text":"Phenotype: Excessive attrition of teeth
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.251
N cases: 840
N controls: 259234"}
{"pvalue":0.121,"sign":-1,"group":"K11: Digestive system diseases","label":"Barrett oesophagus","text":"Phenotype: Barrett oesophagus
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.121
N cases: 1123
N controls: 320387"}
{"pvalue":0.513,"sign":1,"group":"K11: Digestive system diseases","label":"Other diseases of biliary tract","text":"Phenotype: Other diseases of biliary tract
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.513
N cases: 2294
N controls: 330903"}
{"pvalue":0.232,"sign":-1,"group":"K11: Digestive system diseases","label":"Dental caries 1, only avohilmo","text":"Phenotype: Dental caries 1, only avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.232
N cases: 161113
N controls: 216164"}
{"pvalue":0.887,"sign":1,"group":"K11: Digestive system diseases","label":"Dental caries 2","text":"Phenotype: Dental caries 2
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.887
N cases: 25095
N controls: 352182"}
{"pvalue":0.577,"sign":1,"group":"K11: Digestive system diseases","label":"Dentinal caries","text":"Phenotype: Dentinal caries
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.577
N cases: 7680
N controls: 259234"}
{"pvalue":0.658,"sign":1,"group":"K11: Digestive system diseases","label":"Crohn disease (strict definition, require KELA, min 2 HDR)","text":"Phenotype: Crohn disease (strict definition, require KELA, min 2 HDR)
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.658
N cases: 1665
N controls: 375445"}
{"pvalue":0.504,"sign":-1,"group":"K11: Digestive system diseases","label":"Cholangitis (primary sclerosing, PSC)","text":"Phenotype: Cholangitis (primary sclerosing, PSC)
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.504
N cases: 1715
N controls: 330903"}
{"pvalue":0.00146,"sign":1,"group":"K11: Digestive system diseases","label":"Cholecystectomy","text":"Phenotype: Cholecystectomy
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00146
N cases: 26778
N controls: 350499"}
{"pvalue":0.968,"sign":-1,"group":"K11: Digestive system diseases","label":"Cholecystitis","text":"Phenotype: Cholecystitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.968
N cases: 4299
N controls: 330903"}
{"pvalue":0.00064,"sign":1,"group":"K11: Digestive system diseases","label":"Cholelithiasis","text":"Phenotype: Cholelithiasis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.000638
N cases: 37041
N controls: 330903"}
{"pvalue":0.296,"sign":-1,"group":"K11: Digestive system diseases","label":"Chronic gastritis","text":"Phenotype: Chronic gastritis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.296
N cases: 9570
N controls: 320387"}
{"pvalue":0.569,"sign":1,"group":"K11: Digestive system diseases","label":"Chronic hepatitis, not elsewhere classified","text":"Phenotype: Chronic hepatitis, not elsewhere classified
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.569
N cases: 885
N controls: 366450"}
{"pvalue":0.0437,"sign":1,"group":"K11: Digestive system diseases","label":"Chronic pancreatitis","text":"Phenotype: Chronic pancreatitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0437
N cases: 3320
N controls: 330903"}
{"pvalue":0.567,"sign":-1,"group":"K11: Digestive system diseases","label":"Coeliac disease","text":"Phenotype: Coeliac disease
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.567
N cases: 3690
N controls: 361055"}
{"pvalue":0.531,"sign":-1,"group":"K11: Digestive system diseases","label":"Constipation","text":"Phenotype: Constipation
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.531
N cases: 36022
N controls: 341255"}
{"pvalue":0.00834,"sign":-1,"group":"K11: Digestive system diseases","label":"Crossbite","text":"Phenotype: Crossbite
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00834
N cases: 1678
N controls: 375599"}
{"pvalue":0.316,"sign":-1,"group":"K11: Digestive system diseases","label":"Crowding of teeth, including avohilmo","text":"Phenotype: Crowding of teeth, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.316
N cases: 2468
N controls: 374809"}
{"pvalue":0.512,"sign":-1,"group":"K11: Digestive system diseases","label":"Deep bite , including avohilmo","text":"Phenotype: Deep bite , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.512
N cases: 2804
N controls: 374473"}
{"pvalue":0.572,"sign":-1,"group":"K11: Digestive system diseases","label":"Deep bite that required surgery","text":"Phenotype: Deep bite that required surgery
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.572
N cases: 293
N controls: 376984"}
{"pvalue":0.618,"sign":-1,"group":"K11: Digestive system diseases","label":"Dentofacial anomalies [including malocclusion]","text":"Phenotype: Dentofacial anomalies [including malocclusion]
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.618
N cases: 9866
N controls: 259234"}
{"pvalue":0.236,"sign":-1,"group":"K11: Digestive system diseases","label":"Deposits [accretions] on teeth","text":"Phenotype: Deposits [accretions] on teeth
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.236
N cases: 1974
N controls: 259234"}
{"pvalue":0.0333,"sign":1,"group":"K11: Digestive system diseases","label":"Diaphragmatic hernia","text":"Phenotype: Diaphragmatic hernia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0333
N cases: 11757
N controls: 322586"}
{"pvalue":0.877,"sign":-1,"group":"K11: Digestive system diseases","label":"Other diseases of liver","text":"Phenotype: Other diseases of liver
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.877
N cases: 5052
N controls: 366450"}
{"pvalue":0.899,"sign":1,"group":"K11: Digestive system diseases","label":"Disorders of oesophagus in diseases classified elsewhere","text":"Phenotype: Disorders of oesophagus in diseases classified elsewhere
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.899
N cases: 523
N controls: 320387"}
{"pvalue":0.522,"sign":1,"group":"K11: Digestive system diseases","label":"Other disorders of teeth and supporting structures","text":"Phenotype: Other disorders of teeth and supporting structures
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.522
N cases: 6850
N controls: 259234"}
{"pvalue":0.224,"sign":-1,"group":"K11: Digestive system diseases","label":"Distal bite , including avohilmo","text":"Phenotype: Distal bite , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.224
N cases: 771
N controls: 376506"}
{"pvalue":0.917,"sign":1,"group":"K11: Digestive system diseases","label":"Diverticular disease of intestine","text":"Phenotype: Diverticular disease of intestine
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.917
N cases: 30649
N controls: 301931"}
{"pvalue":0.751,"sign":1,"group":"K11: Digestive system diseases","label":"Duodenal ulcer","text":"Phenotype: Duodenal ulcer
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.751
N cases: 3520
N controls: 320387"}
{"pvalue":0.838,"sign":1,"group":"K11: Digestive system diseases","label":"Embedded teeth, including avohilmo","text":"Phenotype: Embedded teeth, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.838
N cases: 2429
N controls: 374848"}
{"pvalue":0.459,"sign":-1,"group":"K11: Digestive system diseases","label":"Embedded and impacted teeth , including avohilmo","text":"Phenotype: Embedded and impacted teeth , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.459
N cases: 8139
N controls: 369138"}
{"pvalue":0.655,"sign":-1,"group":"K11: Digestive system diseases","label":"Noninfective enteritis and colitis","text":"Phenotype: Noninfective enteritis and colitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.655
N cases: 17350
N controls: 359927"}
{"pvalue":0.842,"sign":1,"group":"K11: Digestive system diseases","label":"Erosion of teeth","text":"Phenotype: Erosion of teeth
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.842
N cases: 425
N controls: 259234"}
{"pvalue":0.0218,"sign":1,"group":"K11: Digestive system diseases","label":"Erosion of teeth, including avohilmo","text":"Phenotype: Erosion of teeth, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0218
N cases: 5521
N controls: 371756"}
{"pvalue":0.394,"sign":1,"group":"K11: Digestive system diseases","label":"Tooth eruption problems , including avohilmo","text":"Phenotype: Tooth eruption problems , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.394
N cases: 3805
N controls: 373472"}
{"pvalue":0.844,"sign":1,"group":"K11: Digestive system diseases","label":"Femoral hernia","text":"Phenotype: Femoral hernia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.844
N cases: 1267
N controls: 322586"}
{"pvalue":0.325,"sign":-1,"group":"K11: Digestive system diseases","label":"Fibrosis and cirrhosis of liver","text":"Phenotype: Fibrosis and cirrhosis of liver
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.325
N cases: 1841
N controls: 366450"}
{"pvalue":0.911,"sign":-1,"group":"K11: Digestive system diseases","label":"Colonic or urogenital fistula","text":"Phenotype: Colonic or urogenital fistula
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.911
N cases: 8879
N controls: 368398"}
{"pvalue":0.636,"sign":1,"group":"K11: Digestive system diseases","label":"Functional dyspepsia","text":"Phenotype: Functional dyspepsia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.636
N cases: 8875
N controls: 320387"}
{"pvalue":0.269,"sign":1,"group":"K11: Digestive system diseases","label":"Other diseases of gallbladder","text":"Phenotype: Other diseases of gallbladder
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.269
N cases: 1200
N controls: 330903"}
{"pvalue":0.465,"sign":1,"group":"K11: Digestive system diseases","label":"Gastroduodenal ulcer","text":"Phenotype: Gastroduodenal ulcer
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.465
N cases: 9216
N controls: 320387"}
{"pvalue":0.0289,"sign":-1,"group":"K11: Digestive system diseases","label":"Other disorders of gingiva or/and edentulous alveolar ridge","text":"Phenotype: Other disorders of gingiva or/and edentulous alveolar ridge
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0289
N cases: 899
N controls: 259234"}
{"pvalue":0.0652,"sign":-1,"group":"K11: Digestive system diseases","label":"Gingival hyperplasia","text":"Phenotype: Gingival hyperplasia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0652
N cases: 379
N controls: 259234"}
{"pvalue":0.898,"sign":1,"group":"K11: Digestive system diseases","label":"Gingivitis and periodontal diseases","text":"Phenotype: Gingivitis and periodontal diseases
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.898
N cases: 87497
N controls: 259234"}
{"pvalue":0.115,"sign":-1,"group":"K11: Digestive system diseases","label":"Gastrojejunal ulcer","text":"Phenotype: Gastrojejunal ulcer
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.115
N cases: 324
N controls: 320387"}
{"pvalue":0.145,"sign":1,"group":"K11: Digestive system diseases","label":"Gastric ulcer","text":"Phenotype: Gastric ulcer
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.145
N cases: 5935
N controls: 320387"}
{"pvalue":0.2,"sign":-1,"group":"K11: Digestive system diseases","label":"Haemmorrhoids and perianal venous thrombosis","text":"Phenotype: Haemmorrhoids and perianal venous thrombosis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.2
N cases: 8583
N controls: 301931"}
{"pvalue":0.764,"sign":1,"group":"K11: Digestive system diseases","label":"Hepatic failure, not elsewhere classified","text":"Phenotype: Hepatic failure, not elsewhere classified
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.764
N cases: 948
N controls: 366450"}
{"pvalue":0.723,"sign":1,"group":"K11: Digestive system diseases","label":"Inguinal hernia","text":"Phenotype: Inguinal hernia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.723
N cases: 32335
N controls: 322586"}
{"pvalue":0.182,"sign":1,"group":"K11: Digestive system diseases","label":"Hernia","text":"Phenotype: Hernia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.182
N cases: 54691
N controls: 322586"}
{"pvalue":0.682,"sign":1,"group":"K11: Digestive system diseases","label":"Hypertrophy of tongue papillae","text":"Phenotype: Hypertrophy of tongue papillae
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.682
N cases: 268
N controls: 377009"}
{"pvalue":0.253,"sign":-1,"group":"K11: Digestive system diseases","label":"Hypoplasia of dental enamel","text":"Phenotype: Hypoplasia of dental enamel
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.253
N cases: 218
N controls: 376688"}
{"pvalue":0.118,"sign":1,"group":"K11: Digestive system diseases","label":"Tooth agenesis EXCLUDE clefts and syndromes , including avohilmo","text":"Phenotype: Tooth agenesis EXCLUDE clefts and syndromes , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.118
N cases: 920
N controls: 375469"}
{"pvalue":0.0819,"sign":-1,"group":"K11: Digestive system diseases","label":"Hypoplasia of dental enamel , including avohilmo","text":"Phenotype: Hypoplasia of dental enamel , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0819
N cases: 540
N controls: 376737"}
{"pvalue":0.161,"sign":-1,"group":"K11: Digestive system diseases","label":"Hypoplasia of dental enamel, prenatal , including avohilmo","text":"Phenotype: Hypoplasia of dental enamel, prenatal , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.161
N cases: 94
N controls: 377183"}
{"pvalue":0.98,"sign":-1,"group":"K11: Digestive system diseases","label":"Inflammatory bowel disease, strict (require KELA)","text":"Phenotype: Inflammatory bowel disease, strict (require KELA)
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.98
N cases: 7625
N controls: 369652"}
{"pvalue":0.922,"sign":1,"group":"K11: Digestive system diseases","label":"Irritable bowel syndrome","text":"Phenotype: Irritable bowel syndrome
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.922
N cases: 9323
N controls: 301931"}
{"pvalue":0.0419,"sign":1,"group":"K11: Digestive system diseases","label":"Paralytic ileus and intestinal obstruction","text":"Phenotype: Paralytic ileus and intestinal obstruction
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0419
N cases: 8660
N controls: 301931"}
{"pvalue":0.472,"sign":-1,"group":"K11: Digestive system diseases","label":"Impacted teeth , including avohilmo","text":"Phenotype: Impacted teeth , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.472
N cases: 5435
N controls: 371842"}
{"pvalue":0.97,"sign":-1,"group":"K11: Digestive system diseases","label":"Impaction of intestines","text":"Phenotype: Impaction of intestines
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.97
N cases: 189
N controls: 301931"}
{"pvalue":0.927,"sign":1,"group":"K11: Digestive system diseases","label":"Other diseases of intestines","text":"Phenotype: Other diseases of intestines
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.927
N cases: 75346
N controls: 301931"}
{"pvalue":0.244,"sign":1,"group":"K11: Digestive system diseases","label":"Intussusception","text":"Phenotype: Intussusception
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.244
N cases: 555
N controls: 301931"}
{"pvalue":0.758,"sign":-1,"group":"K11: Digestive system diseases","label":"Other diseases of jaws","text":"Phenotype: Other diseases of jaws
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.758
N cases: 1958
N controls: 259234"}
{"pvalue":0.968,"sign":-1,"group":"K11: Digestive system diseases","label":"IBD patients in KELA-register","text":"Phenotype: IBD patients in KELA-register
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.968
N cases: 7625
N controls: 359927"}
{"pvalue":0.692,"sign":-1,"group":"K11: Digestive system diseases","label":"Other diseases of lip and oral mucosa","text":"Phenotype: Other diseases of lip and oral mucosa
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.692
N cases: 4895
N controls: 259234"}
{"pvalue":0.642,"sign":-1,"group":"K11: Digestive system diseases","label":"Diseases of liver","text":"Phenotype: Diseases of liver
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.642
N cases: 10827
N controls: 366450"}
{"pvalue":0.342,"sign":1,"group":"K11: Digestive system diseases","label":"Major anomalies of jaw size , including avohilmo","text":"Phenotype: Major anomalies of jaw size , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.342
N cases: 719
N controls: 376558"}
{"pvalue":0.25,"sign":1,"group":"K11: Digestive system diseases","label":"Intestinal malabsorption","text":"Phenotype: Intestinal malabsorption
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.25
N cases: 1228
N controls: 361055"}
{"pvalue":0.377,"sign":-1,"group":"K11: Digestive system diseases","label":"Mandibular hypoplasia","text":"Phenotype: Mandibular hypoplasia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.377
N cases: 166
N controls: 377111"}
{"pvalue":0.388,"sign":-1,"group":"K11: Digestive system diseases","label":"Impacted maxillary canine","text":"Phenotype: Impacted maxillary canine
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.388
N cases: 183
N controls: 377094"}
{"pvalue":0.117,"sign":-1,"group":"K11: Digestive system diseases","label":"Palatinal maxillary canine","text":"Phenotype: Palatinal maxillary canine
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.117
N cases: 154
N controls: 377123"}
{"pvalue":0.12,"sign":1,"group":"K11: Digestive system diseases","label":"Impacted maxillary molar","text":"Phenotype: Impacted maxillary molar
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.12
N cases: 1375
N controls: 375902"}
{"pvalue":0.018,"sign":-1,"group":"K11: Digestive system diseases","label":"Maxillary prognathism","text":"Phenotype: Maxillary prognathism
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.018
N cases: 105
N controls: 377172"}
{"pvalue":0.817,"sign":-1,"group":"K11: Digestive system diseases","label":"Mesial bite","text":"Phenotype: Mesial bite
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.817
N cases: 219
N controls: 377058"}
{"pvalue":0.0107,"sign":-1,"group":"K11: Digestive system diseases","label":"Molar incisor enamel hypoplasia, with caries","text":"Phenotype: Molar incisor enamel hypoplasia, with caries
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0107
N cases: 187
N controls: 368407"}
{"pvalue":0.0929,"sign":-1,"group":"K11: Digestive system diseases","label":"Molar incisor enamel hypoplasia , including avohilmo","text":"Phenotype: Molar incisor enamel hypoplasia , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0929
N cases: 589
N controls: 376688"}
{"pvalue":0.827,"sign":1,"group":"K11: Digestive system diseases","label":"Missing teeth due to accident, extraction or parodontitis","text":"Phenotype: Missing teeth due to accident, extraction or parodontitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.827
N cases: 3291
N controls: 259234"}
{"pvalue":0.593,"sign":1,"group":"K11: Digestive system diseases","label":"Mandibular prognathia AND surgery (LeFortI or BSSRO)","text":"Phenotype: Mandibular prognathia AND surgery (LeFortI or BSSRO)
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.593
N cases: 118
N controls: 377064"}
{"pvalue":0.523,"sign":1,"group":"K11: Digestive system diseases","label":"Mandibular prognathia AND surgery (LeFortI or BSSO or LeFortI AND BSSO) , including avohilmo","text":"Phenotype: Mandibular prognathia AND surgery (LeFortI or BSSO or LeFortI AND BSSO) , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.523
N cases: 213
N controls: 377064"}
{"pvalue":0.966,"sign":-1,"group":"K11: Digestive system diseases","label":"Mandibular prognathia , including avohilmo","text":"Phenotype: Mandibular prognathia , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.966
N cases: 347
N controls: 376930"}
{"pvalue":0.714,"sign":-1,"group":"K11: Digestive system diseases","label":"Mandibular retrognathia AND surgery (BSSRO)","text":"Phenotype: Mandibular retrognathia AND surgery (BSSRO)
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.714
N cases: 666
N controls: 376611"}
{"pvalue":0.754,"sign":-1,"group":"K11: Digestive system diseases","label":"Mandibular retrognathia","text":"Phenotype: Mandibular retrognathia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.754
N cases: 1703
N controls: 375574"}
{"pvalue":0.46,"sign":-1,"group":"K11: Digestive system diseases","label":"Oesophagitis","text":"Phenotype: Oesophagitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.46
N cases: 1520
N controls: 320387"}
{"pvalue":0.523,"sign":1,"group":"K11: Digestive system diseases","label":"Oesophageal obstruction","text":"Phenotype: Oesophageal obstruction
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.523
N cases: 993
N controls: 320387"}
{"pvalue":0.218,"sign":1,"group":"K11: Digestive system diseases","label":"Diseases of oesophagus, stomach and duodenum","text":"Phenotype: Diseases of oesophagus, stomach and duodenum
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.218
N cases: 56890
N controls: 320387"}
{"pvalue":0.436,"sign":-1,"group":"K11: Digestive system diseases","label":"Ulcer of oesophagus, drug-induced","text":"Phenotype: Ulcer of oesophagus, drug-induced
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.436
N cases: 137
N controls: 377140"}
{"pvalue":0.613,"sign":-1,"group":"K11: Digestive system diseases","label":"Ulcer of oesophagus","text":"Phenotype: Ulcer of oesophagus
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.613
N cases: 2064
N controls: 320387"}
{"pvalue":0.885,"sign":-1,"group":"K11: Digestive system diseases","label":"Open bite , including avohilmo","text":"Phenotype: Open bite , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.885
N cases: 1255
N controls: 376022"}
{"pvalue":0.0664,"sign":-1,"group":"K11: Digestive system diseases","label":"Open bite that required surgery (Lefort1 or BSSRO)","text":"Phenotype: Open bite that required surgery (Lefort1 or BSSRO)
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0664
N cases: 237
N controls: 377040"}
{"pvalue":0.952,"sign":-1,"group":"K11: Digestive system diseases","label":"Cysts of oral region, not elsewhere classified","text":"Phenotype: Cysts of oral region, not elsewhere classified
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.952
N cases: 1223
N controls: 259234"}
{"pvalue":0.654,"sign":1,"group":"K11: Digestive system diseases","label":"Diseases of oral cavity, salivary glands and jaws","text":"Phenotype: Diseases of oral cavity, salivary glands and jaws
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.654
N cases: 118043
N controls: 259234"}
{"pvalue":0.0331,"sign":-1,"group":"K11: Digestive system diseases","label":"Oral leukoplakia","text":"Phenotype: Oral leukoplakia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0331
N cases: 474
N controls: 376803"}
{"pvalue":0.171,"sign":-1,"group":"K11: Digestive system diseases","label":"Oral leukoplakia, including avohilmo","text":"Phenotype: Oral leukoplakia, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.171
N cases: 686
N controls: 376591"}
{"pvalue":0.895,"sign":1,"group":"K11: Digestive system diseases","label":"Oral leukoplakia and related diseases","text":"Phenotype: Oral leukoplakia and related diseases
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.895
N cases: 1531
N controls: 375746"}
{"pvalue":0.955,"sign":-1,"group":"K11: Digestive system diseases","label":"Oral leukoplakia and related diseases, including avohilmo","text":"Phenotype: Oral leukoplakia and related diseases, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.955
N cases: 2382
N controls: 374895"}
{"pvalue":0.327,"sign":1,"group":"K11: Digestive system diseases","label":"Oral lichen ruber planus, hypothyreosis or thyroxin","text":"Phenotype: Oral lichen ruber planus, hypothyreosis or thyroxin
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.327
N cases: 327
N controls: 376950"}
{"pvalue":0.175,"sign":1,"group":"K11: Digestive system diseases","label":"Oral lichen ruber planus","text":"Phenotype: Oral lichen ruber planus
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.175
N cases: 510
N controls: 376767"}
{"pvalue":0.0232,"sign":1,"group":"K11: Digestive system diseases","label":"Oral lichen ruber planus, including avohilmo","text":"Phenotype: Oral lichen ruber planus, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0232
N cases: 1319
N controls: 375958"}
{"pvalue":0.193,"sign":1,"group":"K11: Digestive system diseases","label":"Oral lichen ruber planus, wide definition","text":"Phenotype: Oral lichen ruber planus, wide definition
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.193
N cases: 5791
N controls: 371486"}
{"pvalue":0.3,"sign":-1,"group":"K11: Digestive system diseases","label":"Oral lichen ruber planus wide, hypothyreosis or thyroxin","text":"Phenotype: Oral lichen ruber planus wide, hypothyreosis or thyroxin
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.3
N cases: 1268
N controls: 376009"}
{"pvalue":0.00613,"sign":1,"group":"K11: Digestive system diseases","label":"Other and unspecified abdominal hernia","text":"Phenotype: Other and unspecified abdominal hernia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00613
N cases: 1088
N controls: 322586"}
{"pvalue":0.755,"sign":1,"group":"K11: Digestive system diseases","label":"Other diseases of anus and rectum","text":"Phenotype: Other diseases of anus and rectum
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.755
N cases: 9932
N controls: 301931"}
{"pvalue":0.455,"sign":-1,"group":"K11: Digestive system diseases","label":"Other diseases of appendix","text":"Phenotype: Other diseases of appendix
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.455
N cases: 303
N controls: 346283"}
{"pvalue":0.348,"sign":1,"group":"K11: Digestive system diseases","label":"Other diseases of the digestive system","text":"Phenotype: Other diseases of the digestive system
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.348
N cases: 16222
N controls: 361055"}
{"pvalue":0.342,"sign":1,"group":"K11: Digestive system diseases","label":"Other diseases of the digestive system","text":"Phenotype: Other diseases of the digestive system
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.342
N cases: 10589
N controls: 361055"}
{"pvalue":0.953,"sign":-1,"group":"K11: Digestive system diseases","label":"Other diseases of oesophagus","text":"Phenotype: Other diseases of oesophagus
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.953
N cases: 2936
N controls: 320387"}
{"pvalue":0.662,"sign":1,"group":"K11: Digestive system diseases","label":"Other diseases of stomach and duodenum","text":"Phenotype: Other diseases of stomach and duodenum
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.662
N cases: 1806
N controls: 320387"}
{"pvalue":0.66,"sign":1,"group":"K11: Digestive system diseases","label":"Other noninfective gastroenteritis and colitis","text":"Phenotype: Other noninfective gastroenteritis and colitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.66
N cases: 7988
N controls: 359927"}
{"pvalue":0.563,"sign":1,"group":"K11: Digestive system diseases","label":"Other functional intestinal disorders","text":"Phenotype: Other functional intestinal disorders
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.563
N cases: 16311
N controls: 301931"}
{"pvalue":0.778,"sign":1,"group":"K11: Digestive system diseases","label":"Other gastritis (incl. Duodenitis)","text":"Phenotype: Other gastritis (incl. Duodenitis)
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.778
N cases: 7514
N controls: 320387"}
{"pvalue":0.0837,"sign":1,"group":"K11: Digestive system diseases","label":"Other or unspecified ileus, impaction or obstruction","text":"Phenotype: Other or unspecified ileus, impaction or obstruction
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0837
N cases: 5925
N controls: 301931"}
{"pvalue":0.695,"sign":1,"group":"K11: Digestive system diseases","label":"Other inflammatory liver diseases","text":"Phenotype: Other inflammatory liver diseases
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.695
N cases: 1821
N controls: 366450"}
{"pvalue":0.41,"sign":-1,"group":"K11: Digestive system diseases","label":"Other diseases of intestine","text":"Phenotype: Other diseases of intestine
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.41
N cases: 3131
N controls: 301931"}
{"pvalue":0.531,"sign":-1,"group":"K11: Digestive system diseases","label":"Other diseases of peritoneum","text":"Phenotype: Other diseases of peritoneum
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.531
N cases: 1289
N controls: 374197"}
{"pvalue":0.807,"sign":-1,"group":"K11: Digestive system diseases","label":"Overjet","text":"Phenotype: Overjet
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.807
N cases: 492
N controls: 376785"}
{"pvalue":0.965,"sign":-1,"group":"K11: Digestive system diseases","label":"Other diseases of pancreas","text":"Phenotype: Other diseases of pancreas
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.965
N cases: 1791
N controls: 330903"}
{"pvalue":0.39,"sign":1,"group":"K11: Digestive system diseases","label":"Paralytic ileus","text":"Phenotype: Paralytic ileus
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.39
N cases: 1065
N controls: 301931"}
{"pvalue":0.391,"sign":-1,"group":"K11: Digestive system diseases","label":"Parodontitis or/and operation codes","text":"Phenotype: Parodontitis or/and operation codes
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.391
N cases: 27833
N controls: 349444"}
{"pvalue":0.37,"sign":-1,"group":"K11: Digestive system diseases","label":"Parodontitis or operation codes","text":"Phenotype: Parodontitis or operation codes
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.37
N cases: 30377
N controls: 346900"}
{"pvalue":0.301,"sign":1,"group":"K11: Digestive system diseases","label":"Chronic periapical parodontitis","text":"Phenotype: Chronic periapical parodontitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.301
N cases: 6466
N controls: 259234"}
{"pvalue":0.247,"sign":1,"group":"K11: Digestive system diseases","label":"Perforation of oesophagus","text":"Phenotype: Perforation of oesophagus
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.247
N cases: 114
N controls: 320387"}
{"pvalue":0.184,"sign":-1,"group":"K11: Digestive system diseases","label":"Chronic periodontitis, complicated","text":"Phenotype: Chronic periodontitis, complicated
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.184
N cases: 2462
N controls: 374815"}
{"pvalue":0.616,"sign":-1,"group":"K11: Digestive system diseases","label":"Chronic periodontitis","text":"Phenotype: Chronic periodontitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.616
N cases: 4434
N controls: 259234"}
{"pvalue":0.981,"sign":1,"group":"K11: Digestive system diseases","label":"Periodontal disease, other/unspecified","text":"Phenotype: Periodontal disease, other/unspecified
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.981
N cases: 92
N controls: 289780"}
{"pvalue":0.176,"sign":-1,"group":"K11: Digestive system diseases","label":"Diseases of peritoneum","text":"Phenotype: Diseases of peritoneum
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.176
N cases: 3080
N controls: 374197"}
{"pvalue":0.173,"sign":-1,"group":"K11: Digestive system diseases","label":"Acute peritonitis","text":"Phenotype: Acute peritonitis
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.173
N cases: 1810
N controls: 374197"}
{"pvalue":0.338,"sign":1,"group":"K11: Digestive system diseases","label":"Postprocedural disorders of digestive system, not elsewhere classified","text":"Phenotype: Postprocedural disorders of digestive system, not elsewhere classified
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.338
N cases: 821
N controls: 361055"}
{"pvalue":0.628,"sign":-1,"group":"K11: Digestive system diseases","label":"Colitis, primary sclerosing, strict definition","text":"Phenotype: Colitis, primary sclerosing, strict definition
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.628
N cases: 297
N controls: 375562"}
{"pvalue":0.189,"sign":-1,"group":"K11: Digestive system diseases","label":"Peptic ulcer","text":"Phenotype: Peptic ulcer
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.189
N cases: 264
N controls: 320387"}
{"pvalue":0.434,"sign":1,"group":"K11: Digestive system diseases","label":"Dental pulpitis 1, only avohilmo","text":"Phenotype: Dental pulpitis 1, only avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.434
N cases: 81713
N controls: 295564"}
{"pvalue":0.61,"sign":-1,"group":"K11: Digestive system diseases","label":"Dental pulpitis 3","text":"Phenotype: Dental pulpitis 3
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.61
N cases: 4261
N controls: 373016"}
{"pvalue":0.0542,"sign":1,"group":"K11: Digestive system diseases","label":"Diseases of pulp and periapical tissues","text":"Phenotype: Diseases of pulp and periapical tissues
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0542
N cases: 12078
N controls: 259234"}
{"pvalue":0.213,"sign":1,"group":"K11: Digestive system diseases","label":"Pathological resorption of teeth","text":"Phenotype: Pathological resorption of teeth
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.213
N cases: 154
N controls: 259234"}
{"pvalue":0.0643,"sign":-1,"group":"K11: Digestive system diseases","label":"Maxillary retrognathism , including avohilmo","text":"Phenotype: Maxillary retrognathism , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0643
N cases: 443
N controls: 376834"}
{"pvalue":0.538,"sign":1,"group":"K11: Digestive system diseases","label":"Diseases of salivary glands","text":"Phenotype: Diseases of salivary glands
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.538
N cases: 6269
N controls: 259234"}
{"pvalue":0.0238,"sign":-1,"group":"K11: Digestive system diseases","label":"Scissor bite , including avohilmo","text":"Phenotype: Scissor bite , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0238
N cases: 518
N controls: 376759"}
{"pvalue":0.502,"sign":-1,"group":"K11: Digestive system diseases","label":"Stomatitis and related lesions","text":"Phenotype: Stomatitis and related lesions
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.502
N cases: 2459
N controls: 259234"}
{"pvalue":0.854,"sign":-1,"group":"K11: Digestive system diseases","label":"Supernumerary teeth EXCLUDE clefts and syndromes","text":"Phenotype: Supernumerary teeth EXCLUDE clefts and syndromes
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.854
N cases: 103
N controls: 377174"}
{"pvalue":0.109,"sign":-1,"group":"K11: Digestive system diseases","label":"Supernumerary teeth EXCLUDE clefts and syndromes , including avohilmo","text":"Phenotype: Supernumerary teeth EXCLUDE clefts and syndromes , including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.109
N cases: 220
N controls: 376724"}
{"pvalue":0.994,"sign":1,"group":"K11: Digestive system diseases","label":"Other diseases of hard tissues of teeth","text":"Phenotype: Other diseases of hard tissues of teeth
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.994
N cases: 3132
N controls: 259234"}
{"pvalue":0.172,"sign":1,"group":"K11: Digestive system diseases","label":"Disease of hard tissues of teeth, NOS","text":"Phenotype: Disease of hard tissues of teeth, NOS
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.172
N cases: 125
N controls: 259234"}
{"pvalue":0.511,"sign":1,"group":"K11: Digestive system diseases","label":"Disorders of tooth development and eruption","text":"Phenotype: Disorders of tooth development and eruption
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.511
N cases: 1579
N controls: 259234"}
{"pvalue":0.489,"sign":-1,"group":"K11: Digestive system diseases","label":"Toxic liver disease","text":"Phenotype: Toxic liver disease
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.489
N cases: 388
N controls: 366450"}
{"pvalue":0.594,"sign":-1,"group":"K11: Digestive system diseases","label":"Ulcerative colitis (strict definition, require KELA, min 2 HDR)","text":"Phenotype: Ulcerative colitis (strict definition, require KELA, min 2 HDR)
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.594
N cases: 5034
N controls: 371530"}
{"pvalue":0.103,"sign":1,"group":"K11: Digestive system diseases","label":"Umbilical hernia","text":"Phenotype: Umbilical hernia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.103
N cases: 8510
N controls: 322586"}
{"pvalue":0.572,"sign":1,"group":"K11: Digestive system diseases","label":"Vascular disorders of the intestines","text":"Phenotype: Vascular disorders of the intestines
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.572
N cases: 1802
N controls: 301931"}
{"pvalue":0.132,"sign":1,"group":"K11: Digestive system diseases","label":"Ventral hernia","text":"Phenotype: Ventral hernia
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.132
N cases: 7628
N controls: 322586"}
{"pvalue":0.664,"sign":1,"group":"K11: Digestive system diseases","label":"Volvulus","text":"Phenotype: Volvulus
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.664
N cases: 702
N controls: 301931"}
{"pvalue":0.871,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Cutaneous abscess, furuncle and carbuncle","text":"Phenotype: Cutaneous abscess, furuncle and carbuncle
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.871
N cases: 8157
N controls: 355969"}
{"pvalue":0.621,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Acanthosis nigricans","text":"Phenotype: Acanthosis nigricans
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.621
N cases: 93
N controls: 353088"}
{"pvalue":0.549,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Acne conglobata","text":"Phenotype: Acne conglobata
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.549
N cases: 128
N controls: 361140"}
{"pvalue":0.0117,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Acne","text":"Phenotype: Acne
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0117
N cases: 2787
N controls: 361140"}
{"pvalue":0.795,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified acne","text":"Phenotype: Other and unspecified acne
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.795
N cases: 335
N controls: 361140"}
{"pvalue":0.327,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Acquired keratosis [keratoderma] palmaris et plantaris","text":"Phenotype: Acquired keratosis [keratoderma] palmaris et plantaris
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.327
N cases: 115
N controls: 353088"}
{"pvalue":0.0471,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Actinic keratosis","text":"Phenotype: Actinic keratosis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0471
N cases: 11081
N controls: 364831"}
{"pvalue":0.0373,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Allergic contact dermatitis","text":"Phenotype: Allergic contact dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0373
N cases: 4336
N controls: 336589"}
{"pvalue":0.505,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Androgenic alopecia","text":"Phenotype: Androgenic alopecia
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.505
N cases: 195
N controls: 201019"}
{"pvalue":0.433,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Alopecia areata","text":"Phenotype: Alopecia areata
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.433
N cases: 682
N controls: 361140"}
{"pvalue":0.479,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Apocrine sweat disorders, other sweat gland disorders","text":"Phenotype: Apocrine sweat disorders, other sweat gland disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.479
N cases: 106
N controls: 361140"}
{"pvalue":1.36e-07,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Atopic dermatitis","text":"Phenotype: Atopic dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 1.36e-07
N cases: 13473
N controls: 336589"}
{"pvalue":0.559,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Atrophic disorders of skin","text":"Phenotype: Atrophic disorders of skin
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.559
N cases: 3839
N controls: 353088"}
{"pvalue":0.0832,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified atrophic disorders of skin","text":"Phenotype: Other and unspecified atrophic disorders of skin
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0832
N cases: 115
N controls: 353088"}
{"pvalue":0.209,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other bullous disorders","text":"Phenotype: Other bullous disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.209
N cases: 710
N controls: 375767"}
{"pvalue":0.326,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Bullous disorders","text":"Phenotype: Bullous disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.326
N cases: 1510
N controls: 375767"}
{"pvalue":0.168,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Cellulitis","text":"Phenotype: Cellulitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.168
N cases: 6683
N controls: 355969"}
{"pvalue":0.897,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Chloasma","text":"Phenotype: Chloasma
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.897
N cases: 95
N controls: 353088"}
{"pvalue":0.581,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Chronic ulcer of skin, not elsewhere classified","text":"Phenotype: Chronic ulcer of skin, not elsewhere classified
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.581
N cases: 1840
N controls: 353088"}
{"pvalue":0.103,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Corns and callosities","text":"Phenotype: Corns and callosities
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.103
N cases: 1978
N controls: 353088"}
{"pvalue":0.0634,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Cutis laxa senilis","text":"Phenotype: Cutis laxa senilis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0634
N cases: 184
N controls: 364831"}
{"pvalue":0.88,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Decubitus ulcer and pressure area","text":"Phenotype: Decubitus ulcer and pressure area
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.88
N cases: 1479
N controls: 353088"}
{"pvalue":0.107,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Dermatitis herpetiformis","text":"Phenotype: Dermatitis herpetiformis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.107
N cases: 483
N controls: 375767"}
{"pvalue":0.00011,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Dermatitis and eczema","text":"Phenotype: Dermatitis and eczema
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.000107
N cases: 40688
N controls: 336589"}
{"pvalue":0.119,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified dermatitis","text":"Phenotype: Other and unspecified dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.119
N cases: 21951
N controls: 336589"}
{"pvalue":0.312,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Nummular dermatitis","text":"Phenotype: Nummular dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.312
N cases: 2164
N controls: 336589"}
{"pvalue":0.3,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Disorders of skin appendages","text":"Phenotype: Disorders of skin appendages
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.3
N cases: 16137
N controls: 361140"}
{"pvalue":0.762,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Dyshidrosis [pompholyx]","text":"Phenotype: Dyshidrosis [pompholyx]
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.762
N cases: 405
N controls: 336589"}
{"pvalue":0.816,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other epidermal thickening","text":"Phenotype: Other epidermal thickening
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.816
N cases: 1112
N controls: 353088"}
{"pvalue":0.646,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified epidermal thickening","text":"Phenotype: Other and unspecified epidermal thickening
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.646
N cases: 685
N controls: 353088"}
{"pvalue":0.58,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Erythema multiforme","text":"Phenotype: Erythema multiforme
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.58
N cases: 612
N controls: 364583"}
{"pvalue":0.47,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Erythema nodosum","text":"Phenotype: Erythema nodosum
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.47
N cases: 814
N controls: 364583"}
{"pvalue":0.966,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other erythematous conditions","text":"Phenotype: Other erythematous conditions
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.966
N cases: 878
N controls: 364583"}
{"pvalue":0.919,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Universal erythroderma, KELA reimbursement","text":"Phenotype: Universal erythroderma, KELA reimbursement
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.919
N cases: 389
N controls: 364583"}
{"pvalue":0.843,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Erythema intertrigo","text":"Phenotype: Erythema intertrigo
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.843
N cases: 570
N controls: 336589"}
{"pvalue":0.324,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Exfoliative dermatitis","text":"Phenotype: Exfoliative dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.324
N cases: 298
N controls: 336589"}
{"pvalue":0.631,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Factitial dermatitis","text":"Phenotype: Factitial dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.631
N cases: 135
N controls: 353088"}
{"pvalue":0.24,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other follicular disorders","text":"Phenotype: Other follicular disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.24
N cases: 1918
N controls: 361140"}
{"pvalue":0.609,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Follicular cysts of skin and subcutaneous tissue","text":"Phenotype: Follicular cysts of skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.609
N cases: 5459
N controls: 361140"}
{"pvalue":0.0268,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified follicular disorders","text":"Phenotype: Other and unspecified follicular disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0268
N cases: 971
N controls: 361140"}
{"pvalue":0.174,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Dermatitis due to ingested food","text":"Phenotype: Dermatitis due to ingested food
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.174
N cases: 955
N controls: 336589"}
{"pvalue":0.634,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Foreign body granuloma of skin and subcutaneous tissue","text":"Phenotype: Foreign body granuloma of skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.634
N cases: 87
N controls: 353088"}
{"pvalue":0.914,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Granuloma annulare","text":"Phenotype: Granuloma annulare
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.914
N cases: 354
N controls: 353088"}
{"pvalue":0.178,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified granulomatous disorders of skin and subcutaneous tissue","text":"Phenotype: Other and unspecified granulomatous disorders of skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.178
N cases: 91
N controls: 353088"}
{"pvalue":0.926,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Granulomatous disorders of skin and subcutaneous tissue","text":"Phenotype: Granulomatous disorders of skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.926
N cases: 679
N controls: 353088"}
{"pvalue":0.355,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Hair colour and hair shaft abnormalities","text":"Phenotype: Hair colour and hair shaft abnormalities
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.355
N cases: 113
N controls: 361140"}
{"pvalue":0.409,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other nonscarring hair loss","text":"Phenotype: Other nonscarring hair loss
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.409
N cases: 198
N controls: 361140"}
{"pvalue":0.8,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified nonscarring hair loss","text":"Phenotype: Other and unspecified nonscarring hair loss
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.8
N cases: 147
N controls: 361140"}
{"pvalue":0.801,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Cicatricial alopecia [scarring hair loss]","text":"Phenotype: Cicatricial alopecia [scarring hair loss]
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.801
N cases: 187
N controls: 361140"}
{"pvalue":0.449,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Hidradenitis suppurativa","text":"Phenotype: Hidradenitis suppurativa
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.449
N cases: 931
N controls: 361140"}
{"pvalue":0.0637,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Hirsutism in women","text":"Phenotype: Hirsutism in women
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0637
N cases: 458
N controls: 201019"}
{"pvalue":0.366,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other hypertrichosis","text":"Phenotype: Other hypertrichosis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.366
N cases: 82
N controls: 361140"}
{"pvalue":0.524,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified hypertrophic disorders of skin","text":"Phenotype: Other and unspecified hypertrophic disorders of skin
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.524
N cases: 143
N controls: 353088"}
{"pvalue":0.939,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Hypertrophic scar","text":"Phenotype: Hypertrophic scar
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.939
N cases: 1476
N controls: 353088"}
{"pvalue":0.171,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Impetigo","text":"Phenotype: Impetigo
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.171
N cases: 1215
N controls: 355969"}
{"pvalue":0.252,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Infective dermatitis","text":"Phenotype: Infective dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.252
N cases: 3405
N controls: 336589"}
{"pvalue":0.0365,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Infections of the skin and subcutaneous tissue","text":"Phenotype: Infections of the skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0365
N cases: 21308
N controls: 355969"}
{"pvalue":0.162,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other local infections of skin and subcutaneous tissue","text":"Phenotype: Other local infections of skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.162
N cases: 2801
N controls: 355969"}
{"pvalue":0.663,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Dermatitis due to substances taken internally","text":"Phenotype: Dermatitis due to substances taken internally
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.663
N cases: 2469
N controls: 336589"}
{"pvalue":0.726,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Lichen planus","text":"Phenotype: Lichen planus
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.726
N cases: 3597
N controls: 364071"}
{"pvalue":0.486,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Lichen planus, including avohilmo","text":"Phenotype: Lichen planus, including avohilmo
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.486
N cases: 5015
N controls: 372262"}
{"pvalue":0.571,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Lichen sclerosus et atrophicus","text":"Phenotype: Lichen sclerosus et atrophicus
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.571
N cases: 2445
N controls: 353088"}
{"pvalue":0.333,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Lichen simplex chronicus","text":"Phenotype: Lichen simplex chronicus
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.333
N cases: 901
N controls: 336589"}
{"pvalue":0.51,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Lichen simplex chronicus and prurigo","text":"Phenotype: Lichen simplex chronicus and prurigo
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.51
N cases: 1703
N controls: 336589"}
{"pvalue":0.116,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Livedoid vasculitis","text":"Phenotype: Livedoid vasculitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.116
N cases: 86
N controls: 353088"}
{"pvalue":0.868,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified localized connective tissue disorders","text":"Phenotype: Other and unspecified localized connective tissue disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.868
N cases: 82
N controls: 353088"}
{"pvalue":0.904,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other localized connective tissue disorders","text":"Phenotype: Other localized connective tissue disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.904
N cases: 493
N controls: 353088"}
{"pvalue":0.643,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Localized scleroderma [morphea]","text":"Phenotype: Localized scleroderma [morphea]
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.643
N cases: 361
N controls: 353088"}
{"pvalue":0.688,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Lupus erythematosus","text":"Phenotype: Lupus erythematosus
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.688
N cases: 652
N controls: 353088"}
{"pvalue":0.11,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Acute lymphadenitis","text":"Phenotype: Acute lymphadenitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.11
N cases: 1812
N controls: 355969"}
{"pvalue":0.706,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Nail disorders","text":"Phenotype: Nail disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.706
N cases: 2254
N controls: 361140"}
{"pvalue":0.461,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Nail dystrophy","text":"Phenotype: Nail dystrophy
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.461
N cases: 167
N controls: 361140"}
{"pvalue":0.372,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Ingrowing nail","text":"Phenotype: Ingrowing nail
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.372
N cases: 1477
N controls: 361140"}
{"pvalue":0.603,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Onycholysis","text":"Phenotype: Onycholysis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.603
N cases: 153
N controls: 361140"}
{"pvalue":0.605,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified nail disorders","text":"Phenotype: Other and unspecified nail disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.605
N cases: 453
N controls: 361140"}
{"pvalue":0.877,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Necrobiosis lipoidica, not elsewhere classified","text":"Phenotype: Necrobiosis lipoidica, not elsewhere classified
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.877
N cases: 161
N controls: 353088"}
{"pvalue":0.592,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified skin changes due to chronic exposure to nonionizing radiation","text":"Phenotype: Other and unspecified skin changes due to chronic exposure to nonionizing radiation
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.592
N cases: 353
N controls: 364831"}
{"pvalue":0.891,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other acute skin changes due to ultraviolet radiation","text":"Phenotype: Other acute skin changes due to ultraviolet radiation
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.891
N cases: 996
N controls: 364831"}
{"pvalue":0.917,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified acute skin changes due to ultraviolet radiation","text":"Phenotype: Other and unspecified acute skin changes due to ultraviolet radiation
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.917
N cases: 732
N controls: 364831"}
{"pvalue":0.811,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified bullous disorders","text":"Phenotype: Other and unspecified bullous disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.811
N cases: 242
N controls: 375767"}
{"pvalue":0.0208,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other contact dermatitis","text":"Phenotype: Other contact dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0208
N cases: 2490
N controls: 336589"}
{"pvalue":0.614,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other disorders of skin and subcutaneous tissue, not elsewhere classified","text":"Phenotype: Other disorders of skin and subcutaneous tissue, not elsewhere classified
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.614
N cases: 4387
N controls: 353088"}
{"pvalue":0.682,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other infiltrative disorders of skin and subcutaneous tissue","text":"Phenotype: Other infiltrative disorders of skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.682
N cases: 120
N controls: 353088"}
{"pvalue":0.0538,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other melanin hyperpigmentation","text":"Phenotype: Other melanin hyperpigmentation
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0538
N cases: 510
N controls: 353088"}
{"pvalue":0.748,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other disorders of skin and subcutaneous tissue","text":"Phenotype: Other disorders of skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.748
N cases: 24189
N controls: 353088"}
{"pvalue":0.173,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other disorders of pigmentation","text":"Phenotype: Other disorders of pigmentation
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.173
N cases: 1080
N controls: 353088"}
{"pvalue":0.00984,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Papulosquamous disorders","text":"Phenotype: Papulosquamous disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00984
N cases: 13206
N controls: 364071"}
{"pvalue":0.158,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other papulosquamous disorders","text":"Phenotype: Other papulosquamous disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.158
N cases: 263
N controls: 364071"}
{"pvalue":0.269,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified papulosquamous disorders","text":"Phenotype: Other and unspecified papulosquamous disorders
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.269
N cases: 139
N controls: 364071"}
{"pvalue":0.512,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pityriasis lichenoides chronica","text":"Phenotype: Pityriasis lichenoides chronica
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.512
N cases: 103
N controls: 364071"}
{"pvalue":0.661,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified parapsoriasis","text":"Phenotype: Other and unspecified parapsoriasis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.661
N cases: 113
N controls: 364071"}
{"pvalue":0.764,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Parapsoriasis","text":"Phenotype: Parapsoriasis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.764
N cases: 488
N controls: 364071"}
{"pvalue":0.935,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Bullous pemphigoid","text":"Phenotype: Bullous pemphigoid
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.935
N cases: 507
N controls: 375767"}
{"pvalue":0.491,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified pemphigoid","text":"Phenotype: Other and unspecified pemphigoid
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.491
N cases: 186
N controls: 375767"}
{"pvalue":0.448,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pemphigus","text":"Phenotype: Pemphigus
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.448
N cases: 162
N controls: 375767"}
{"pvalue":0.76,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Perioral dermatitis","text":"Phenotype: Perioral dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.76
N cases: 465
N controls: 361140"}
{"pvalue":0.543,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified disorders of pigmentation","text":"Phenotype: Other and unspecified disorders of pigmentation
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.543
N cases: 181
N controls: 353088"}
{"pvalue":0.863,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pigmented purpuric dermatosis","text":"Phenotype: Pigmented purpuric dermatosis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.863
N cases: 230
N controls: 353088"}
{"pvalue":0.835,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pilonidal cyst","text":"Phenotype: Pilonidal cyst
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.835
N cases: 2739
N controls: 355969"}
{"pvalue":0.535,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pityriasis rosea","text":"Phenotype: Pityriasis rosea
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.535
N cases: 182
N controls: 364071"}
{"pvalue":0.441,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Polymorphous light eruption","text":"Phenotype: Polymorphous light eruption
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.441
N cases: 194
N controls: 364831"}
{"pvalue":0.538,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other prurigo","text":"Phenotype: Other prurigo
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.538
N cases: 283
N controls: 336589"}
{"pvalue":0.266,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Prurigo nodularis","text":"Phenotype: Prurigo nodularis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.266
N cases: 606
N controls: 336589"}
{"pvalue":0.586,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pruritus","text":"Phenotype: Pruritus
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.586
N cases: 2994
N controls: 336589"}
{"pvalue":0.00088,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Psoriasis","text":"Phenotype: Psoriasis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.000876
N cases: 9267
N controls: 364071"}
{"pvalue":0.904,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Guttate psoriasis","text":"Phenotype: Guttate psoriasis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.904
N cases: 343
N controls: 364071"}
{"pvalue":0.0233,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified psoriasis","text":"Phenotype: Other and unspecified psoriasis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0233
N cases: 1667
N controls: 364071"}
{"pvalue":0.188,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Generalized pustular psoriasis","text":"Phenotype: Generalized pustular psoriasis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.188
N cases: 89
N controls: 364071"}
{"pvalue":0.191,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pustulosis palmaris et plantaris","text":"Phenotype: Pustulosis palmaris et plantaris
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.191
N cases: 1112
N controls: 364071"}
{"pvalue":0.024,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Psoriasis vulgaris","text":"Phenotype: Psoriasis vulgaris
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.024
N cases: 5759
N controls: 364071"}
{"pvalue":0.966,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pyoderma gangrenosum","text":"Phenotype: Pyoderma gangrenosum
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.966
N cases: 154
N controls: 353088"}
{"pvalue":0.0753,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pyoderma","text":"Phenotype: Pyoderma
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0753
N cases: 537
N controls: 355969"}
{"pvalue":0.849,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Pyogenic granuloma","text":"Phenotype: Pyogenic granuloma
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.849
N cases: 412
N controls: 353088"}
{"pvalue":0.679,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Rhinophyma","text":"Phenotype: Rhinophyma
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.679
N cases: 135
N controls: 361140"}
{"pvalue":0.349,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified rosacea","text":"Phenotype: Other and unspecified rosacea
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.349
N cases: 2210
N controls: 361140"}
{"pvalue":0.647,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Scar conditions and fibrosis of skin","text":"Phenotype: Scar conditions and fibrosis of skin
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.647
N cases: 1027
N controls: 353088"}
{"pvalue":0.989,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Seborrhoeic dermatitis","text":"Phenotype: Seborrhoeic dermatitis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.989
N cases: 2688
N controls: 336589"}
{"pvalue":0.627,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Seborrhoeic keratosis","text":"Phenotype: Seborrhoeic keratosis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.627
N cases: 5835
N controls: 353088"}
{"pvalue":0.878,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified disorders of skin and subcutaneous tissue","text":"Phenotype: Other and unspecified disorders of skin and subcutaneous tissue
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.878
N cases: 1950
N controls: 353088"}
{"pvalue":0.909,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Striae atrophicae","text":"Phenotype: Striae atrophicae
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.909
N cases: 281
N controls: 353088"}
{"pvalue":0.475,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Ulcer of lower limb, not elsewhere classified","text":"Phenotype: Ulcer of lower limb, not elsewhere classified
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.475
N cases: 3784
N controls: 353088"}
{"pvalue":0.304,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Allergic urticaria","text":"Phenotype: Allergic urticaria
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.304
N cases: 2386
N controls: 364583"}
{"pvalue":0.88,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Cholinergic urticaria","text":"Phenotype: Cholinergic urticaria
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.88
N cases: 130
N controls: 364583"}
{"pvalue":0.178,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Urticaria due to cold and heat","text":"Phenotype: Urticaria due to cold and heat
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.178
N cases: 209
N controls: 364583"}
{"pvalue":0.034,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Dermatographic urticaria","text":"Phenotype: Dermatographic urticaria
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.034
N cases: 1848
N controls: 364583"}
{"pvalue":0.83,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Idiopathic urticaria","text":"Phenotype: Idiopathic urticaria
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.83
N cases: 518
N controls: 364583"}
{"pvalue":0.114,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified urticaria","text":"Phenotype: Other and unspecified urticaria
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.114
N cases: 6381
N controls: 364583"}
{"pvalue":0.0194,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Urticaria","text":"Phenotype: Urticaria
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0194
N cases: 10175
N controls: 364583"}
{"pvalue":0.118,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Other and unspecified vasculitis limited to skin","text":"Phenotype: Other and unspecified vasculitis limited to skin
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.118
N cases: 600
N controls: 353088"}
{"pvalue":0.435,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Vitiligo","text":"Phenotype: Vitiligo
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.435
N cases: 260
N controls: 353088"}
{"pvalue":0.694,"sign":1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Xerosis cutis","text":"Phenotype: Xerosis cutis
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.694
N cases: 326
N controls: 353088"}
{"pvalue":0.885,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Localized skin eruption due to drugs and medicaments","text":"Phenotype: Localized skin eruption due to drugs and medicaments
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.885
N cases: 272
N controls: 377005"}
{"pvalue":0.968,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Abscess of tendon sheath","text":"Phenotype: Abscess of tendon sheath
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.968
N cases: 145
N controls: 275212"}
{"pvalue":0.72,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Achilles tendinitis","text":"Phenotype: Achilles tendinitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.72
N cases: 3113
N controls: 270964"}
{"pvalue":0.116,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Adhesive capsulitis of shoulder","text":"Phenotype: Adhesive capsulitis of shoulder
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.116
N cases: 5538
N controls: 275212"}
{"pvalue":0.772,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Algoneurodystrophy","text":"Phenotype: Algoneurodystrophy
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.772
N cases: 888
N controls: 358014"}
{"pvalue":0.592,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other acquired deformities of ankle and foot","text":"Phenotype: Other acquired deformities of ankle and foot
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.592
N cases: 207
N controls: 240862"}
{"pvalue":0.235,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Ankylosis of joint","text":"Phenotype: Ankylosis of joint
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.235
N cases: 153
N controls: 240862"}
{"pvalue":0.00018,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Ankylosing spondylitis","text":"Phenotype: Ankylosing spondylitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.000183
N cases: 2860
N controls: 270964"}
{"pvalue":0.00466,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Ankylosing spondylitis, strict definition","text":"Phenotype: Ankylosing spondylitis, strict definition
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00466
N cases: 1193
N controls: 374621"}
{"pvalue":0.0228,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Arthropathies in other diseases classified elsewhere","text":"Phenotype: Arthropathies in other diseases classified elsewhere
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0228
N cases: 1060
N controls: 240862"}
{"pvalue":0.512,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Arthropathies","text":"Phenotype: Arthropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.512
N cases: 136415
N controls: 240862"}
{"pvalue":0.353,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Arthrosis","text":"Phenotype: Arthrosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.353
N cases: 73710
N controls: 240862"}
{"pvalue":0.285,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Artrosis, including avohilmo","text":"Phenotype: Artrosis, including avohilmo
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.285
N cases: 96500
N controls: 280777"}
{"pvalue":0.34,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Gonarthrosis","text":"Phenotype: Gonarthrosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.34
N cases: 44688
N controls: 240862"}
{"pvalue":0.398,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Gonarthrosis, primary, with knee surgery","text":"Phenotype: Gonarthrosis, primary, with knee surgery
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.398
N cases: 19126
N controls: 337196"}
{"pvalue":0.743,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other arthrosis","text":"Phenotype: Other arthrosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.743
N cases: 20949
N controls: 240862"}
{"pvalue":0.0665,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Polyarthrosis","text":"Phenotype: Polyarthrosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0665
N cases: 6185
N controls: 240862"}
{"pvalue":0.189,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Coxarthrosis,","text":"Phenotype: Coxarthrosis,
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.189
N cases: 22254
N controls: 240862"}
{"pvalue":0.142,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Coxarthrosis, primary, with hip surgery","text":"Phenotype: Coxarthrosis, primary, with hip surgery
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.142
N cases: 14990
N controls: 357221"}
{"pvalue":0.134,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Coxarthrosis, primary","text":"Phenotype: Coxarthrosis, primary
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.134
N cases: 20056
N controls: 357221"}
{"pvalue":0.0723,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Atlantoaxial subluxation","text":"Phenotype: Atlantoaxial subluxation
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0723
N cases: 176
N controls: 270964"}
{"pvalue":0.0825,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Synovial cyst of popliteal space [Baker]","text":"Phenotype: Synovial cyst of popliteal space [Baker]
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0825
N cases: 2084
N controls: 275212"}
{"pvalue":0.758,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Behçet disease","text":"Phenotype: Behçet disease
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.758
N cases: 85
N controls: 365533"}
{"pvalue":0.682,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Bicipital tendinitis","text":"Phenotype: Bicipital tendinitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.682
N cases: 1317
N controls: 275212"}
{"pvalue":0.261,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Biomechanical lesions, not elsewhere classified","text":"Phenotype: Biomechanical lesions, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.261
N cases: 1105
N controls: 373303"}
{"pvalue":0.714,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Disorders of continuity of bone","text":"Phenotype: Disorders of continuity of bone
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.714
N cases: 2543
N controls: 358014"}
{"pvalue":0.0488,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other disorders of bone density and structure","text":"Phenotype: Other disorders of bone density and structure
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0488
N cases: 677
N controls: 358014"}
{"pvalue":0.907,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified disorders of bone/cartilage","text":"Phenotype: Other specified/unspecified disorders of bone/cartilage
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.907
N cases: 769
N controls: 358014"}
{"pvalue":0.474,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Hypertrophy of bone","text":"Phenotype: Hypertrophy of bone
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.474
N cases: 84
N controls: 358014"}
{"pvalue":0.308,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other bursal cyst","text":"Phenotype: Other bursal cyst
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.308
N cases: 393
N controls: 275212"}
{"pvalue":0.608,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other bursitis of elbow","text":"Phenotype: Other bursitis of elbow
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.608
N cases: 169
N controls: 275212"}
{"pvalue":0.85,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other bursitis of hip","text":"Phenotype: Other bursitis of hip
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.85
N cases: 492
N controls: 275212"}
{"pvalue":0.716,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other bursitis of knee","text":"Phenotype: Other bursitis of knee
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.716
N cases: 347
N controls: 275212"}
{"pvalue":0.0328,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other bursitis, not elsewhere classified","text":"Phenotype: Other bursitis, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0328
N cases: 282
N controls: 275212"}
{"pvalue":0.669,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other bursopathies","text":"Phenotype: Other bursopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.669
N cases: 3988
N controls: 275212"}
{"pvalue":0.86,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Calcaneal spur","text":"Phenotype: Calcaneal spur
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.86
N cases: 300
N controls: 275212"}
{"pvalue":0.999,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Calcific tendinitis of shoulder","text":"Phenotype: Calcific tendinitis of shoulder
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.999
N cases: 1646
N controls: 275212"}
{"pvalue":0.467,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Calcific tendinitis","text":"Phenotype: Calcific tendinitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.467
N cases: 240
N controls: 275212"}
{"pvalue":0.904,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other articular cartilage disorders","text":"Phenotype: Other articular cartilage disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.904
N cases: 723
N controls: 240862"}
{"pvalue":0.672,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Cervicalgia","text":"Phenotype: Cervicalgia
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.672
N cases: 6684
N controls: 270964"}
{"pvalue":0.137,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Cervical disc disorders","text":"Phenotype: Cervical disc disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.137
N cases: 13394
N controls: 270964"}
{"pvalue":0.358,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Cervicobrachial syndrome","text":"Phenotype: Cervicobrachial syndrome
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.358
N cases: 7353
N controls: 270964"}
{"pvalue":0.857,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Cervicocranial syndrome","text":"Phenotype: Cervicocranial syndrome
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.857
N cases: 3149
N controls: 270964"}
{"pvalue":0.964,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Chondromalacia","text":"Phenotype: Chondromalacia
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.964
N cases: 794
N controls: 370709"}
{"pvalue":0.858,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Chondropathies","text":"Phenotype: Chondropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.858
N cases: 4850
N controls: 370709"}
{"pvalue":0.689,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist","text":"Phenotype: Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.689
N cases: 385
N controls: 275212"}
{"pvalue":0.699,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Polyarteritis with lung involvement [Churg-Strauss]/EGPA","text":"Phenotype: Polyarteritis with lung involvement [Churg-Strauss]/EGPA
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.699
N cases: 99
N controls: 365533"}
{"pvalue":0.25,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Acquired clawhand, clubhand, clawfoot and clubfoot","text":"Phenotype: Acquired clawhand, clubhand, clawfoot and clubfoot
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.25
N cases: 131
N controls: 240862"}
{"pvalue":0.422,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified systemic involvement of connective tissue","text":"Phenotype: Other specified/unspecified systemic involvement of connective tissue
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.422
N cases: 1676
N controls: 365533"}
{"pvalue":0.632,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Contracture of joint","text":"Phenotype: Contracture of joint
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.632
N cases: 329
N controls: 240862"}
{"pvalue":0.515,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other crystal arthropathies","text":"Phenotype: Other crystal arthropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.515
N cases: 444
N controls: 240862"}
{"pvalue":0.171,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other acquired deformities of musculoskeletal system and connective tissue","text":"Phenotype: Other acquired deformities of musculoskeletal system and connective tissue
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.171
N cases: 1249
N controls: 373303"}
{"pvalue":0.814,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Deforming dorsopathies","text":"Phenotype: Deforming dorsopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.814
N cases: 9672
N controls: 270964"}
{"pvalue":0.0858,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified deforming dorsopathies","text":"Phenotype: Other specified/unspecified deforming dorsopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0858
N cases: 530
N controls: 270964"}
{"pvalue":0.811,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Radial styloid tenosynovitis [de Quervain]","text":"Phenotype: Radial styloid tenosynovitis [de Quervain]
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.811
N cases: 1552
N controls: 275212"}
{"pvalue":0.353,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other dermatomyositis","text":"Phenotype: Other dermatomyositis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.353
N cases: 143
N controls: 365533"}
{"pvalue":0.543,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Dermatopolymyositis, unspecified","text":"Phenotype: Dermatopolymyositis, unspecified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.543
N cases: 147
N controls: 365533"}
{"pvalue":0.874,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Diastasis of muscle","text":"Phenotype: Diastasis of muscle
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.874
N cases: 162
N controls: 275212"}
{"pvalue":0.0361,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Infection of intervertebral disc (pyogenic)","text":"Phenotype: Infection of intervertebral disc (pyogenic)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0361
N cases: 296
N controls: 270964"}
{"pvalue":0.919,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Discitis, unspecified","text":"Phenotype: Discitis, unspecified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.919
N cases: 422
N controls: 270964"}
{"pvalue":0.171,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies","text":"Phenotype: Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.171
N cases: 1354
N controls: 275212"}
{"pvalue":0.514,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Dorsalgia","text":"Phenotype: Dorsalgia
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.514
N cases: 59438
N controls: 270964"}
{"pvalue":0.308,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other/unspecified dorsalgia","text":"Phenotype: Other/unspecified dorsalgia
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.308
N cases: 14075
N controls: 270964"}
{"pvalue":0.286,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Dorsopathies","text":"Phenotype: Dorsopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.286
N cases: 106313
N controls: 270964"}
{"pvalue":0.764,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified dorsopathies","text":"Phenotype: Other specified/unspecified dorsopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.764
N cases: 996
N controls: 270964"}
{"pvalue":0.554,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other dorsopathies, not elsewhere classified","text":"Phenotype: Other dorsopathies, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.554
N cases: 79212
N controls: 270964"}
{"pvalue":0.855,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Palmar fascial fibromatosis [Dupuytren]","text":"Phenotype: Palmar fascial fibromatosis [Dupuytren]
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.855
N cases: 5128
N controls: 275212"}
{"pvalue":0.367,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Early lumbar disc prolapse, operated","text":"Phenotype: Early lumbar disc prolapse, operated
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.367
N cases: 8351
N controls: 368926"}
{"pvalue":0.291,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Enteropathic arthropathies","text":"Phenotype: Enteropathic arthropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.291
N cases: 655
N controls: 240862"}
{"pvalue":0.363,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Enthesopathies of lower limb, excluding foot","text":"Phenotype: Enthesopathies of lower limb, excluding foot
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.363
N cases: 7125
N controls: 270964"}
{"pvalue":0.0264,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other/unspecified enthesopathies of lower limb, excluding foot","text":"Phenotype: Other/unspecified enthesopathies of lower limb, excluding foot
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0264
N cases: 2066
N controls: 270964"}
{"pvalue":0.849,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other/unspecified enthesopathies, not elsewhere classified","text":"Phenotype: Other/unspecified enthesopathies, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.849
N cases: 2763
N controls: 275212"}
{"pvalue":0.662,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other enthesopathies","text":"Phenotype: Other enthesopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.662
N cases: 10581
N controls: 275212"}
{"pvalue":0.955,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Fatigue fracture of vertebra","text":"Phenotype: Fatigue fracture of vertebra
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.955
N cases: 106
N controls: 270964"}
{"pvalue":0.952,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Hypertrophy of (infrapatellar) fat pad","text":"Phenotype: Hypertrophy of (infrapatellar) fat pad
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.952
N cases: 294
N controls: 275212"}
{"pvalue":0.959,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Fibroblastic disorders","text":"Phenotype: Fibroblastic disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.959
N cases: 7952
N controls: 275212"}
{"pvalue":0.35,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other fibroblastic disorders","text":"Phenotype: Other fibroblastic disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.35
N cases: 109
N controls: 275212"}
{"pvalue":0.328,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Fibromyalgia","text":"Phenotype: Fibromyalgia
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.328
N cases: 2314
N controls: 275212"}
{"pvalue":0.38,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Deformity of finger(s)","text":"Phenotype: Deformity of finger(s)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.38
N cases: 162
N controls: 240862"}
{"pvalue":0.845,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Flat foot [pes planus] (acquired)","text":"Phenotype: Flat foot [pes planus] (acquired)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.845
N cases: 2677
N controls: 240862"}
{"pvalue":0.527,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Residual foreign body in soft tissue","text":"Phenotype: Residual foreign body in soft tissue
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.527
N cases: 1368
N controls: 275212"}
{"pvalue":0.46,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Ankylosing hyperostosis [Forestier]","text":"Phenotype: Ankylosing hyperostosis [Forestier]
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.46
N cases: 354
N controls: 270964"}
{"pvalue":0.116,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Ganglion","text":"Phenotype: Ganglion
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.116
N cases: 7270
N controls: 275212"}
{"pvalue":0.358,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Giant cell arteritis","text":"Phenotype: Giant cell arteritis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.358
N cases: 996
N controls: 365533"}
{"pvalue":0.125,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Gluteal tendinitis","text":"Phenotype: Gluteal tendinitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.125
N cases: 854
N controls: 270964"}
{"pvalue":0.0578,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Gout","text":"Phenotype: Gout
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0578
N cases: 8489
N controls: 240862"}
{"pvalue":0.867,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other deformity of hallux (acquired)","text":"Phenotype: Other deformity of hallux (acquired)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.867
N cases: 223
N controls: 240862"}
{"pvalue":0.383,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Hallux rigidus","text":"Phenotype: Hallux rigidus
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.383
N cases: 4459
N controls: 240862"}
{"pvalue":0.614,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Hallux valgus (acquired)","text":"Phenotype: Hallux valgus (acquired)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.614
N cases: 14726
N controls: 240862"}
{"pvalue":0.744,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other hammer toe(s) (acquired)","text":"Phenotype: Other hammer toe(s) (acquired)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.744
N cases: 5625
N controls: 240862"}
{"pvalue":0.434,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Thrombotic microangiopathy","text":"Phenotype: Thrombotic microangiopathy
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.434
N cases: 165
N controls: 365533"}
{"pvalue":0.492,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Hypersensitivity angiitis","text":"Phenotype: Hypersensitivity angiitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.492
N cases: 135
N controls: 365533"}
{"pvalue":0.815,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Hypermobility syndrome","text":"Phenotype: Hypermobility syndrome
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.815
N cases: 1481
N controls: 365533"}
{"pvalue":0.0188,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Iliotibial band syndrome","text":"Phenotype: Iliotibial band syndrome
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0188
N cases: 279
N controls: 270964"}
{"pvalue":0.789,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Impingement syndrome of shoulder","text":"Phenotype: Impingement syndrome of shoulder
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.789
N cases: 8676
N controls: 275212"}
{"pvalue":0.523,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Infective bursitis","text":"Phenotype: Infective bursitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.523
N cases: 743
N controls: 275212"}
{"pvalue":0.488,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other infective (teno)synovitis","text":"Phenotype: Other infective (teno)synovitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.488
N cases: 106
N controls: 275212"}
{"pvalue":0.116,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other intervertebral disc disorders","text":"Phenotype: Other intervertebral disc disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.116
N cases: 37636
N controls: 270964"}
{"pvalue":0.46,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Juvenile rheuma","text":"Phenotype: Juvenile rheuma
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.46
N cases: 692
N controls: 240862"}
{"pvalue":0.929,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Juvenile osteochondrosis","text":"Phenotype: Juvenile osteochondrosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.929
N cases: 953
N controls: 370709"}
{"pvalue":0.235,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Internal derangement of knee","text":"Phenotype: Internal derangement of knee
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.235
N cases: 35511
N controls: 240862"}
{"pvalue":0.505,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Kyphosis","text":"Phenotype: Kyphosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.505
N cases: 317
N controls: 270964"}
{"pvalue":0.136,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Lateral epicondylitis","text":"Phenotype: Lateral epicondylitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.136
N cases: 4278
N controls: 275212"}
{"pvalue":0.602,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other specified acquired deformities of limbs","text":"Phenotype: Other specified acquired deformities of limbs
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.602
N cases: 133
N controls: 240862"}
{"pvalue":0.31,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Unequal limb length (acquired)","text":"Phenotype: Unequal limb length (acquired)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.31
N cases: 234
N controls: 240862"}
{"pvalue":0.962,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Pain in limb","text":"Phenotype: Pain in limb
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.962
N cases: 30485
N controls: 275212"}
{"pvalue":0.856,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Loose body in joint","text":"Phenotype: Loose body in joint
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.856
N cases: 665
N controls: 240862"}
{"pvalue":0.604,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Low back pain","text":"Phenotype: Low back pain
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.604
N cases: 29329
N controls: 270964"}
{"pvalue":0.346,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Lower back pain or/and sciatica","text":"Phenotype: Lower back pain or/and sciatica
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.346
N cases: 41815
N controls: 335462"}
{"pvalue":0.524,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Mixed connective tissue disease","text":"Phenotype: Mixed connective tissue disease
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.524
N cases: 1849
N controls: 375428"}
{"pvalue":0.788,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Medial epicondylitis","text":"Phenotype: Medial epicondylitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.788
N cases: 1062
N controls: 275212"}
{"pvalue":0.023,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Meniscus derangement","text":"Phenotype: Meniscus derangement
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.023
N cases: 24158
N controls: 240862"}
{"pvalue":0.313,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Metatarsalgia","text":"Phenotype: Metatarsalgia
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.313
N cases: 2726
N controls: 275212"}
{"pvalue":0.271,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Microscopic polyangiitis","text":"Phenotype: Microscopic polyangiitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.271
N cases: 143
N controls: 375364"}
{"pvalue":0.755,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Monoarthritis, not elsewhere classified","text":"Phenotype: Monoarthritis, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.755
N cases: 1282
N controls: 240862"}
{"pvalue":0.17,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Multifocal fibrosclerosis","text":"Phenotype: Multifocal fibrosclerosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.17
N cases: 161
N controls: 365533"}
{"pvalue":0.32,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Muscle wasting and atrophy, not elsewhere classified","text":"Phenotype: Muscle wasting and atrophy, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.32
N cases: 163
N controls: 275212"}
{"pvalue":0.768,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other specified disorders of muscle","text":"Phenotype: Other specified disorders of muscle
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.768
N cases: 805
N controls: 275212"}
{"pvalue":0.617,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Disorders of muscles","text":"Phenotype: Disorders of muscles
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.617
N cases: 3008
N controls: 275212"}
{"pvalue":0.777,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Muscle strain","text":"Phenotype: Muscle strain
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.777
N cases: 815
N controls: 275212"}
{"pvalue":0.609,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Contracture of muscle","text":"Phenotype: Contracture of muscle
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.609
N cases: 97
N controls: 275212"}
{"pvalue":0.0815,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other disorders of the musculoskeletal system and connective tissue","text":"Phenotype: Other disorders of the musculoskeletal system and connective tissue
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0815
N cases: 3974
N controls: 373303"}
{"pvalue":0.616,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Myalgia","text":"Phenotype: Myalgia
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.616
N cases: 7024
N controls: 275212"}
{"pvalue":0.51,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Myositis","text":"Phenotype: Myositis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.51
N cases: 692
N controls: 275212"}
{"pvalue":0.109,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Necrotizing fasciitis","text":"Phenotype: Necrotizing fasciitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.109
N cases: 101
N controls: 275212"}
{"pvalue":0.852,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified necrotizing vasculopathies","text":"Phenotype: Other specified/unspecified necrotizing vasculopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.852
N cases: 368
N controls: 365533"}
{"pvalue":0.433,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Neuralgia and neuritis, unspecified","text":"Phenotype: Neuralgia and neuritis, unspecified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.433
N cases: 1413
N controls: 275212"}
{"pvalue":0.15,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Olecranon bursitis","text":"Phenotype: Olecranon bursitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.15
N cases: 1681
N controls: 275212"}
{"pvalue":0.973,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Osteopathies and chondropathies","text":"Phenotype: Osteopathies and chondropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.973
N cases: 19263
N controls: 358014"}
{"pvalue":0.848,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other osteochondropathies","text":"Phenotype: Other osteochondropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.848
N cases: 2091
N controls: 370709"}
{"pvalue":0.244,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Osteomalacia","text":"Phenotype: Osteomalacia
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.244
N cases: 224
N controls: 358014"}
{"pvalue":0.828,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Osteomyelitis","text":"Phenotype: Osteomyelitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.828
N cases: 1758
N controls: 358014"}
{"pvalue":0.776,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Osteomyelitis of vertebra","text":"Phenotype: Osteomyelitis of vertebra
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.776
N cases: 89
N controls: 270964"}
{"pvalue":0.719,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Osteonecrosis","text":"Phenotype: Osteonecrosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.719
N cases: 1385
N controls: 358014"}
{"pvalue":0.929,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Osteopathy in diseases classified elsewhere","text":"Phenotype: Osteopathy in diseases classified elsewhere
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.929
N cases: 166
N controls: 358014"}
{"pvalue":0.243,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Osteoporosis","text":"Phenotype: Osteoporosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.243
N cases: 7300
N controls: 358014"}
{"pvalue":0.95,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other disorders of bone","text":"Phenotype: Other disorders of bone
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.95
N cases: 6568
N controls: 358014"}
{"pvalue":0.333,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other joint disorders","text":"Phenotype: Other joint disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.333
N cases: 81676
N controls: 240862"}
{"pvalue":0.689,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other overlap syndromes","text":"Phenotype: Other overlap syndromes
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.689
N cases: 501
N controls: 365533"}
{"pvalue":0.571,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other/unspecified soft tissue disorders related to use, overuse and pressure","text":"Phenotype: Other/unspecified soft tissue disorders related to use, overuse and pressure
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.571
N cases: 800
N controls: 275212"}
{"pvalue":0.408,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Paget disease","text":"Phenotype: Paget disease
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.408
N cases: 115
N controls: 358014"}
{"pvalue":0.998,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Palindromic rheumatism","text":"Phenotype: Palindromic rheumatism
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.998
N cases: 285
N controls: 240862"}
{"pvalue":0.99,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Panniculitis affecting regions of neck and back","text":"Phenotype: Panniculitis affecting regions of neck and back
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.99
N cases: 1115
N controls: 270964"}
{"pvalue":0.671,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Panniculitis, unspecified","text":"Phenotype: Panniculitis, unspecified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.671
N cases: 279
N controls: 275212"}
{"pvalue":0.237,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Recurrent dislocation of patella","text":"Phenotype: Recurrent dislocation of patella
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.237
N cases: 1645
N controls: 240862"}
{"pvalue":0.997,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other disorders of patella","text":"Phenotype: Other disorders of patella
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.997
N cases: 6333
N controls: 240862"}
{"pvalue":0.34,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Patellar tendinitis","text":"Phenotype: Patellar tendinitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.34
N cases: 439
N controls: 270964"}
{"pvalue":0.186,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Peroneal tendinitis","text":"Phenotype: Peroneal tendinitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.186
N cases: 361
N controls: 270964"}
{"pvalue":0.944,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Plantar fascial fibromatosis","text":"Phenotype: Plantar fascial fibromatosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.944
N cases: 2768
N controls: 275212"}
{"pvalue":0.219,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Polyarteritis nodosa","text":"Phenotype: Polyarteritis nodosa
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.219
N cases: 185
N controls: 365533"}
{"pvalue":0.647,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Polyarteritis nodosa and related conditions","text":"Phenotype: Polyarteritis nodosa and related conditions
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.647
N cases: 373
N controls: 365533"}
{"pvalue":0.0951,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Polyarthritis, unspecified","text":"Phenotype: Polyarthritis, unspecified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0951
N cases: 1047
N controls: 240862"}
{"pvalue":0.0458,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Polyarthropathies","text":"Phenotype: Polyarthropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0458
N cases: 32199
N controls: 240862"}
{"pvalue":0.123,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Polymyalgia rheumatica","text":"Phenotype: Polymyalgia rheumatica
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.123
N cases: 3501
N controls: 365533"}
{"pvalue":0.0336,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Polymyositis","text":"Phenotype: Polymyositis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0336
N cases: 225
N controls: 365533"}
{"pvalue":0.541,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Postprocedural musculoskeletal disorders, not elsewhere classified","text":"Phenotype: Postprocedural musculoskeletal disorders, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.541
N cases: 1725
N controls: 373303"}
{"pvalue":0.991,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Prepatellar bursitis","text":"Phenotype: Prepatellar bursitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.991
N cases: 1210
N controls: 275212"}
{"pvalue":0.492,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Psoas tendinitis","text":"Phenotype: Psoas tendinitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.492
N cases: 105
N controls: 270964"}
{"pvalue":0.011,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Psoriatic arthropathies","text":"Phenotype: Psoriatic arthropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.011
N cases: 3186
N controls: 240862"}
{"pvalue":0.0287,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Pyogenic arthritis","text":"Phenotype: Pyogenic arthritis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0287
N cases: 2029
N controls: 240862"}
{"pvalue":0.144,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Radiculopathy","text":"Phenotype: Radiculopathy
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.144
N cases: 5550
N controls: 270964"}
{"pvalue":0.734,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Reactive arthropathies","text":"Phenotype: Reactive arthropathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.734
N cases: 2813
N controls: 240862"}
{"pvalue":0.808,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Recurrent dislocation and subluxation of joint","text":"Phenotype: Recurrent dislocation and subluxation of joint
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.808
N cases: 2240
N controls: 240862"}
{"pvalue":0.00169,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Rheumatoid arthritis","text":"Phenotype: Rheumatoid arthritis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00169
N cases: 12555
N controls: 240862"}
{"pvalue":0.32,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Rheumatism, unspecified","text":"Phenotype: Rheumatism, unspecified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.32
N cases: 4674
N controls: 275212"}
{"pvalue":0.243,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Rotator cuff syndrome","text":"Phenotype: Rotator cuff syndrome
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.243
N cases: 24061
N controls: 275212"}
{"pvalue":0.695,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other rupture of muscle","text":"Phenotype: Other rupture of muscle
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.695
N cases: 148
N controls: 275212"}
{"pvalue":0.84,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Sacrococcygeal disorders, not elsewhere classified","text":"Phenotype: Sacrococcygeal disorders, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.84
N cases: 872
N controls: 270964"}
{"pvalue":0.12,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Sacroiliitis, not elsewhere classified","text":"Phenotype: Sacroiliitis, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.12
N cases: 1394
N controls: 270964"}
{"pvalue":0.0981,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Sciatica+with lumbago","text":"Phenotype: Sciatica+with lumbago
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0981
N cases: 18569
N controls: 270964"}
{"pvalue":0.048,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Scoliosis","text":"Phenotype: Scoliosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.048
N cases: 2529
N controls: 270964"}
{"pvalue":0.0766,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Short Achilles tendon (acquired)","text":"Phenotype: Short Achilles tendon (acquired)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0766
N cases: 652
N controls: 275212"}
{"pvalue":0.0285,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Bursitis of shoulder","text":"Phenotype: Bursitis of shoulder
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0285
N cases: 651
N controls: 275212"}
{"pvalue":0.489,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Shoulder lesions","text":"Phenotype: Shoulder lesions
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.489
N cases: 34594
N controls: 275212"}
{"pvalue":0.159,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other shoulder lesions","text":"Phenotype: Other shoulder lesions
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.159
N cases: 2663
N controls: 275212"}
{"pvalue":0.986,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Sicca syndrome [Sjögren]","text":"Phenotype: Sicca syndrome [Sjögren]
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.986
N cases: 2495
N controls: 365533"}
{"pvalue":0.0364,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Soft tissue disorders related to use, overuse and pressure","text":"Phenotype: Soft tissue disorders related to use, overuse and pressure
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0364
N cases: 8236
N controls: 275212"}
{"pvalue":0.922,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Soft tissue disorders","text":"Phenotype: Soft tissue disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.922
N cases: 102065
N controls: 275212"}
{"pvalue":0.956,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified soft tissue disorders","text":"Phenotype: Other specified/unspecified soft tissue disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.956
N cases: 1475
N controls: 275212"}
{"pvalue":0.681,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other soft tissue disorders, not elsewhere classified","text":"Phenotype: Other soft tissue disorders, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.681
N cases: 43190
N controls: 275212"}
{"pvalue":0.615,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Spinal osteochondrosis","text":"Phenotype: Spinal osteochondrosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.615
N cases: 318
N controls: 270964"}
{"pvalue":0.884,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Spinal enthesopathy","text":"Phenotype: Spinal enthesopathy
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.884
N cases: 1145
N controls: 270964"}
{"pvalue":0.698,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Spinal instabilities","text":"Phenotype: Spinal instabilities
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.698
N cases: 839
N controls: 270964"}
{"pvalue":0.00019,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Spinal stenosis","text":"Phenotype: Spinal stenosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.000189
N cases: 18989
N controls: 270964"}
{"pvalue":0.75,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified inflammatory spondylopathies","text":"Phenotype: Other specified/unspecified inflammatory spondylopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.75
N cases: 1448
N controls: 270964"}
{"pvalue":0.11,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Spondylolisthesis/Spondylolysis","text":"Phenotype: Spondylolisthesis/Spondylolysis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.11
N cases: 5766
N controls: 270964"}
{"pvalue":0.515,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Spondylopathies in diseases classified elsewhere","text":"Phenotype: Spondylopathies in diseases classified elsewhere
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.515
N cases: 286
N controls: 270964"}
{"pvalue":0.0362,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Spondylopathies","text":"Phenotype: Spondylopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0362
N cases: 38276
N controls: 270964"}
{"pvalue":0.914,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Other specified/unspecified spondylopathies","text":"Phenotype: Other specified/unspecified spondylopathies
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.914
N cases: 693
N controls: 270964"}
{"pvalue":0.00577,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Spondylosis","text":"Phenotype: Spondylosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00577
N cases: 19892
N controls: 270964"}
{"pvalue":0.515,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Spontaneous rupture of synovium and tendon","text":"Phenotype: Spontaneous rupture of synovium and tendon
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.515
N cases: 2313
N controls: 275212"}
{"pvalue":0.388,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Synovial hypertrophy, not elsewhere classified","text":"Phenotype: Synovial hypertrophy, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.388
N cases: 273
N controls: 275212"}
{"pvalue":0.442,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Disorders of synovium and tendon","text":"Phenotype: Disorders of synovium and tendon
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.442
N cases: 20492
N controls: 275212"}
{"pvalue":0.0588,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Disorders of synovium and tendon in diseases classified elsewhere","text":"Phenotype: Disorders of synovium and tendon in diseases classified elsewhere
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0588
N cases: 529
N controls: 275212"}
{"pvalue":0.386,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Systemic disorders of connective tissue in diseases classified elsewhere","text":"Phenotype: Systemic disorders of connective tissue in diseases classified elsewhere
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.386
N cases: 113
N controls: 365533"}
{"pvalue":0.421,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Systemic connective tissue disorders","text":"Phenotype: Systemic connective tissue disorders
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.421
N cases: 11744
N controls: 365533"}
{"pvalue":0.486,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Systemic sclerosis","text":"Phenotype: Systemic sclerosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.486
N cases: 619
N controls: 365533"}
{"pvalue":0.366,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Temporal arteritis","text":"Phenotype: Temporal arteritis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.366
N cases: 891
N controls: 365533"}
{"pvalue":0.686,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Oher contracture of tendon (sheath)","text":"Phenotype: Oher contracture of tendon (sheath)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.686
N cases: 91
N controls: 275212"}
{"pvalue":0.245,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other/unspecified synovitis and tenosynovitis","text":"Phenotype: Other/unspecified synovitis and tenosynovitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.245
N cases: 3704
N controls: 275212"}
{"pvalue":0.62,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Pain in thoracic spine","text":"Phenotype: Pain in thoracic spine
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.62
N cases: 4651
N controls: 270964"}
{"pvalue":0.23,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Tibial collateral bursitis [Pellegrini-Stieda]","text":"Phenotype: Tibial collateral bursitis [Pellegrini-Stieda]
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.23
N cases: 270
N controls: 270964"}
{"pvalue":0.658,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Chondrocostal junction syndrome [Tietze]","text":"Phenotype: Chondrocostal junction syndrome [Tietze]
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.658
N cases: 912
N controls: 370709"}
{"pvalue":0.256,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Other deformities of toe(s)","text":"Phenotype: Other deformities of toe(s)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.256
N cases: 975
N controls: 240862"}
{"pvalue":0.18,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Torticollis","text":"Phenotype: Torticollis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.18
N cases: 460
N controls: 270964"}
{"pvalue":0.151,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Transient synovitis","text":"Phenotype: Transient synovitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.151
N cases: 209
N controls: 275212"}
{"pvalue":0.735,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Trigger finger","text":"Phenotype: Trigger finger
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.735
N cases: 4284
N controls: 275212"}
{"pvalue":0.104,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Trochanteric bursitis","text":"Phenotype: Trochanteric bursitis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.104
N cases: 3529
N controls: 275212"}
{"pvalue":0.264,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Valgus deformity, not elsewhere classified","text":"Phenotype: Valgus deformity, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.264
N cases: 191
N controls: 240862"}
{"pvalue":0.584,"sign":-1,"group":"M13: Musculoskeletal system diseases","label":"Varus deformity, not elsewhere classified","text":"Phenotype: Varus deformity, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.584
N cases: 298
N controls: 240862"}
{"pvalue":0.0122,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Collapsed vertebra, not elsewhere classified","text":"Phenotype: Collapsed vertebra, not elsewhere classified
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0122
N cases: 193
N controls: 270964"}
{"pvalue":0.831,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Villonodular synovitis (pigmented)","text":"Phenotype: Villonodular synovitis (pigmented)
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.831
N cases: 212
N controls: 240862"}
{"pvalue":0.809,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Wegener granulomatosis","text":"Phenotype: Wegener granulomatosis
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.809
N cases: 413
N controls: 365533"}
{"pvalue":0.783,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Degenerative macular diseases, drug-induced","text":"Phenotype: Degenerative macular diseases, drug-induced
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.783
N cases: 84
N controls: 377193"}
{"pvalue":0.173,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Degenerative macular diseases","text":"Phenotype: Degenerative macular diseases
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.173
N cases: 3473
N controls: 344569"}
{"pvalue":0.382,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Macular cyst","text":"Phenotype: Macular cyst
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.382
N cases: 491
N controls: 344569"}
{"pvalue":0.139,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Macular hole","text":"Phenotype: Macular hole
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.139
N cases: 1266
N controls: 344569"}
{"pvalue":0.695,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Macular pucker","text":"Phenotype: Macular pucker
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.695
N cases: 3576
N controls: 344569"}
{"pvalue":0.236,"sign":1,"group":"G6: Nervous system diseases","label":"Migraine, unspecified, drug-induced","text":"Phenotype: Migraine, unspecified, drug-induced
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.236
N cases: 186
N controls: 377091"}
{"pvalue":0.761,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other abnormal uterine and caginal bleeding","text":"Phenotype: Other abnormal uterine and caginal bleeding
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.761
N cases: 10319
N controls: 107564"}
{"pvalue":0.528,"sign":1,"group":"N14: Genitourinary system diseases","label":"Acute nephritic syndrome","text":"Phenotype: Acute nephritic syndrome
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.528
N cases: 581
N controls: 371635"}
{"pvalue":0.0735,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Acute renal failure","text":"Phenotype: Acute renal failure
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0735
N cases: 5908
N controls: 363177"}
{"pvalue":0.669,"sign":1,"group":"N14: Genitourinary system diseases","label":"Amenorrhoea","text":"Phenotype: Amenorrhoea
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.669
N cases: 2220
N controls: 107564"}
{"pvalue":0.177,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Abscess of Bartholin gland","text":"Phenotype: Abscess of Bartholin gland
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.177
N cases: 699
N controls: 188295"}
{"pvalue":0.506,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Cyst of Bartholin Gland","text":"Phenotype: Cyst of Bartholin Gland
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.506
N cases: 1055
N controls: 188295"}
{"pvalue":0.643,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other and unspecified disease of Bartholin gland","text":"Phenotype: Other and unspecified disease of Bartholin gland
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.643
N cases: 807
N controls: 188295"}
{"pvalue":0.52,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Benign mammary dysplasia","text":"Phenotype: Benign mammary dysplasia
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.52
N cases: 4329
N controls: 193973"}
{"pvalue":0.797,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Other disorders of breast","text":"Phenotype: Other disorders of breast
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.797
N cases: 3450
N controls: 193973"}
{"pvalue":0.145,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Disorders of breast","text":"Phenotype: Disorders of breast
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.145
N cases: 16897
N controls: 193973"}
{"pvalue":0.201,"sign":1,"group":"N14: Genitourinary system diseases","label":"Calculus of kidney and ureter","text":"Phenotype: Calculus of kidney and ureter
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.201
N cases: 9713
N controls: 366693"}
{"pvalue":0.401,"sign":1,"group":"N14: Genitourinary system diseases","label":"Calculus of lower urinary tract","text":"Phenotype: Calculus of lower urinary tract
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.401
N cases: 1398
N controls: 366693"}
{"pvalue":0.355,"sign":1,"group":"N14: Genitourinary system diseases","label":"All dysplastic lesions of the cervix uteri","text":"Phenotype: All dysplastic lesions of the cervix uteri
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.355
N cases: 8025
N controls: 202845"}
{"pvalue":0.32,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Dysplastic lesion of unknown severity of the cervix uteri","text":"Phenotype: Dysplastic lesion of unknown severity of the cervix uteri
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.32
N cases: 242
N controls: 210628"}
{"pvalue":0.879,"sign":1,"group":"N14: Genitourinary system diseases","label":"HSIL lesion of the cervix uteri","text":"Phenotype: HSIL lesion of the cervix uteri
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.879
N cases: 5459
N controls: 205411"}
{"pvalue":0.116,"sign":1,"group":"N14: Genitourinary system diseases","label":"LSIL lesion of the cervix uteri","text":"Phenotype: LSIL lesion of the cervix uteri
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.116
N cases: 3207
N controls: 207663"}
{"pvalue":0.155,"sign":1,"group":"N14: Genitourinary system diseases","label":"Chronic nephritic syndrome","text":"Phenotype: Chronic nephritic syndrome
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.155
N cases: 1098
N controls: 371635"}
{"pvalue":0.583,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Chronic kidney disease","text":"Phenotype: Chronic kidney disease
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.583
N cases: 9073
N controls: 363177"}
{"pvalue":0.661,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Chronic tubulo-interstitial nephritis","text":"Phenotype: Chronic tubulo-interstitial nephritis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.661
N cases: 1127
N controls: 338942"}
{"pvalue":0.125,"sign":1,"group":"N14: Genitourinary system diseases","label":"Cystitis","text":"Phenotype: Cystitis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.125
N cases: 18080
N controls: 328001"}
{"pvalue":0.816,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Cyst of kidney","text":"Phenotype: Cyst of kidney
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.816
N cases: 1696
N controls: 373761"}
{"pvalue":0.211,"sign":1,"group":"N14: Genitourinary system diseases","label":"Dialysis","text":"Phenotype: Dialysis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.211
N cases: 1004
N controls: 363177"}
{"pvalue":0.305,"sign":1,"group":"N14: Genitourinary system diseases","label":"Disorders resulting from impaired renal tubular function","text":"Phenotype: Disorders resulting from impaired renal tubular function
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.305
N cases: 859
N controls: 373761"}
{"pvalue":0.472,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Endometriosis diagnosis and infertility diagnosis occurring together","text":"Phenotype: Endometriosis diagnosis and infertility diagnosis occurring together
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.472
N cases: 3206
N controls: 201035"}
{"pvalue":0.606,"sign":1,"group":"N14: Genitourinary system diseases","label":"Endometriosis ASRM stages 1,2","text":"Phenotype: Endometriosis ASRM stages 1,2
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.606
N cases: 5769
N controls: 205101"}
{"pvalue":0.877,"sign":1,"group":"N14: Genitourinary system diseases","label":"Endometriosis ASRM stages 3,4","text":"Phenotype: Endometriosis ASRM stages 3,4
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.877
N cases: 7574
N controls: 203296"}
{"pvalue":0.306,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Deep endometriosis","text":"Phenotype: Deep endometriosis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.306
N cases: 2856
N controls: 203296"}
{"pvalue":0.498,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Endometriosis of fallopian tube","text":"Phenotype: Endometriosis of fallopian tube
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.498
N cases: 213
N controls: 107564"}
{"pvalue":0.28,"sign":1,"group":"N14: Genitourinary system diseases","label":"Endometriosis","text":"Phenotype: Endometriosis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.28
N cases: 15088
N controls: 107564"}
{"pvalue":0.232,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Endometriosis of intestine","text":"Phenotype: Endometriosis of intestine
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.232
N cases: 436
N controls: 107564"}
{"pvalue":0.573,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Unspecified/other endometriosis","text":"Phenotype: Unspecified/other endometriosis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.573
N cases: 2982
N controls: 107564"}
{"pvalue":0.694,"sign":1,"group":"N14: Genitourinary system diseases","label":"Endometriosis of ovary","text":"Phenotype: Endometriosis of ovary
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.694
N cases: 5867
N controls: 107564"}
{"pvalue":0.44,"sign":1,"group":"N14: Genitourinary system diseases","label":"Endometriosis of pelvic peritoneum","text":"Phenotype: Endometriosis of pelvic peritoneum
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.44
N cases: 5628
N controls: 107564"}
{"pvalue":0.652,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Endometriosis of rectovaginal septum and vagina","text":"Phenotype: Endometriosis of rectovaginal septum and vagina
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.652
N cases: 2456
N controls: 107564"}
{"pvalue":0.168,"sign":1,"group":"N14: Genitourinary system diseases","label":"Adenomyosis (Endometriosis of uterus)","text":"Phenotype: Adenomyosis (Endometriosis of uterus)
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.168
N cases: 4267
N controls: 107564"}
{"pvalue":0.953,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Erosion and ectropion of cervix uteri","text":"Phenotype: Erosion and ectropion of cervix uteri
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.953
N cases: 830
N controls: 107564"}
{"pvalue":0.0597,"sign":1,"group":"N14: Genitourinary system diseases","label":"Inflammatory diseases of female pelvic organs","text":"Phenotype: Inflammatory diseases of female pelvic organs
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0597
N cases: 22575
N controls: 188295"}
{"pvalue":0.237,"sign":1,"group":"N14: Genitourinary system diseases","label":"All dysplastic lesions of the cervix uteri, vagina or vulva","text":"Phenotype: All dysplastic lesions of the cervix uteri, vagina or vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.237
N cases: 9227
N controls: 201643"}
{"pvalue":0.43,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva","text":"Phenotype: Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.43
N cases: 302
N controls: 210568"}
{"pvalue":0.626,"sign":1,"group":"N14: Genitourinary system diseases","label":"HSIL lesion of the cervix uteri, vagina or vulva","text":"Phenotype: HSIL lesion of the cervix uteri, vagina or vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.626
N cases: 5996
N controls: 204874"}
{"pvalue":0.0843,"sign":1,"group":"N14: Genitourinary system diseases","label":"LSIL lesion of the cervix uteri, vagina or vulva","text":"Phenotype: LSIL lesion of the cervix uteri, vagina or vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0843
N cases: 4102
N controls: 206768"}
{"pvalue":0.114,"sign":1,"group":"N14: Genitourinary system diseases","label":"Noninflammatory disorders of female genital tract","text":"Phenotype: Noninflammatory disorders of female genital tract
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.114
N cases: 103306
N controls: 107564"}
{"pvalue":0.283,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Female infertility","text":"Phenotype: Female infertility
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.283
N cases: 13142
N controls: 107564"}
{"pvalue":0.943,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Fistulae involving female genital tract","text":"Phenotype: Fistulae involving female genital tract
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.943
N cases: 424
N controls: 107564"}
{"pvalue":0.375,"sign":1,"group":"N14: Genitourinary system diseases","label":"Pain and other conditions associated with female genital organs and menstrual cycle","text":"Phenotype: Pain and other conditions associated with female genital organs and menstrual cycle
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.375
N cases: 6976
N controls: 107564"}
{"pvalue":0.258,"sign":1,"group":"N14: Genitourinary system diseases","label":"Female genital prolapse","text":"Phenotype: Female genital prolapse
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.258
N cases: 17150
N controls: 107564"}
{"pvalue":0.121,"sign":1,"group":"N14: Genitourinary system diseases","label":"Female pelvic inflammatory disorders in diseases classified elsewhere","text":"Phenotype: Female pelvic inflammatory disorders in diseases classified elsewhere
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.121
N cases: 98
N controls: 188295"}
{"pvalue":0.173,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Female infertility, associated with anovulation","text":"Phenotype: Female infertility, associated with anovulation
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.173
N cases: 2441
N controls: 107564"}
{"pvalue":0.32,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Female infertility, cervigal, vaginal, other or unspecified origin","text":"Phenotype: Female infertility, cervigal, vaginal, other or unspecified origin
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.32
N cases: 11348
N controls: 107564"}
{"pvalue":0.961,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Female infertility, tubal origin","text":"Phenotype: Female infertility, tubal origin
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.961
N cases: 1483
N controls: 107564"}
{"pvalue":0.67,"sign":1,"group":"N14: Genitourinary system diseases","label":"Female infertility, uterine origin","text":"Phenotype: Female infertility, uterine origin
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.67
N cases: 99
N controls: 107564"}
{"pvalue":0.167,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Galactorrhea","text":"Phenotype: Galactorrhea
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.167
N cases: 272
N controls: 193973"}
{"pvalue":0.793,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other disorders of the genitourinary system","text":"Phenotype: Other disorders of the genitourinary system
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.793
N cases: 3607
N controls: 373670"}
{"pvalue":0.454,"sign":1,"group":"N14: Genitourinary system diseases","label":"Glomerular disorders in diseases classified elsewhere","text":"Phenotype: Glomerular disorders in diseases classified elsewhere
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.454
N cases: 3374
N controls: 371635"}
{"pvalue":0.107,"sign":1,"group":"N14: Genitourinary system diseases","label":"Glomerulonephritis","text":"Phenotype: Glomerulonephritis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.107
N cases: 1605
N controls: 375672"}
{"pvalue":0.825,"sign":1,"group":"N14: Genitourinary system diseases","label":"Glomerular diseases","text":"Phenotype: Glomerular diseases
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.825
N cases: 5642
N controls: 371635"}
{"pvalue":0.339,"sign":1,"group":"N14: Genitourinary system diseases","label":"Habitual aborter","text":"Phenotype: Habitual aborter
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.339
N cases: 571
N controls: 107564"}
{"pvalue":0.366,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Henoch-Schönlein purpura nephritis (HSPN)","text":"Phenotype: Henoch-Schönlein purpura nephritis (HSPN)
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.366
N cases: 94
N controls: 377183"}
{"pvalue":0.0448,"sign":1,"group":"N14: Genitourinary system diseases","label":"Hydrocele","text":"Phenotype: Hydrocele
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0448
N cases: 5221
N controls: 119297"}
{"pvalue":0.0388,"sign":1,"group":"N14: Genitourinary system diseases","label":"Hydronephrosis","text":"Phenotype: Hydronephrosis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0388
N cases: 3252
N controls: 338942"}
{"pvalue":0.752,"sign":1,"group":"N14: Genitourinary system diseases","label":"Hypertrophy of breast in women and men","text":"Phenotype: Hypertrophy of breast in women and men
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.752
N cases: 6105
N controls: 359487"}
{"pvalue":0.69,"sign":1,"group":"N14: Genitourinary system diseases","label":"Hypertrophy of breast","text":"Phenotype: Hypertrophy of breast
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.69
N cases: 5212
N controls: 193973"}
{"pvalue":0.0229,"sign":1,"group":"N14: Genitourinary system diseases","label":"IgA nephropathy (IgA glomerulonephritis)","text":"Phenotype: IgA nephropathy (IgA glomerulonephritis)
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0229
N cases: 592
N controls: 376685"}
{"pvalue":0.867,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Impotence","text":"Phenotype: Impotence
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.867
N cases: 1264
N controls: 119297"}
{"pvalue":0.819,"sign":1,"group":"N14: Genitourinary system diseases","label":"Inflammatory disease of cervix uteri","text":"Phenotype: Inflammatory disease of cervix uteri
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.819
N cases: 1847
N controls: 188295"}
{"pvalue":0.92,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Inflammatory disorders of male genital organs, not elsewhere classified","text":"Phenotype: Inflammatory disorders of male genital organs, not elsewhere classified
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.92
N cases: 357
N controls: 119297"}
{"pvalue":1,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Inflammatory disorders of breast","text":"Phenotype: Inflammatory disorders of breast
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 1
N cases: 1668
N controls: 193973"}
{"pvalue":0.696,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Inflammatory disease of uterus","text":"Phenotype: Inflammatory disease of uterus
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.696
N cases: 4337
N controls: 188295"}
{"pvalue":0.219,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Isolated proteinuria with specified morphological lesion","text":"Phenotype: Isolated proteinuria with specified morphological lesion
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.219
N cases: 288
N controls: 371635"}
{"pvalue":0.947,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other disorders of kidney and ureter","text":"Phenotype: Other disorders of kidney and ureter
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.947
N cases: 3516
N controls: 373761"}
{"pvalue":0.0265,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Unspecified lump in breast","text":"Phenotype: Unspecified lump in breast
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0265
N cases: 4681
N controls: 193973"}
{"pvalue":0.784,"sign":1,"group":"N14: Genitourinary system diseases","label":"Diseases of male genital organs","text":"Phenotype: Diseases of male genital organs
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.784
N cases: 47110
N controls: 119297"}
{"pvalue":0.685,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Disorders of male genital organs in diseases classified elsewhere","text":"Phenotype: Disorders of male genital organs in diseases classified elsewhere
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.685
N cases: 142
N controls: 119297"}
{"pvalue":0.0075,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Male infertility","text":"Phenotype: Male infertility
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0075
N cases: 1271
N controls: 119297"}
{"pvalue":0.0328,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other menopausal disorders","text":"Phenotype: Other menopausal disorders
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0328
N cases: 4777
N controls: 107564"}
{"pvalue":0.408,"sign":1,"group":"N14: Genitourinary system diseases","label":"Menorrhagia","text":"Phenotype: Menorrhagia
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.408
N cases: 21496
N controls: 107564"}
{"pvalue":0.0198,"sign":1,"group":"N14: Genitourinary system diseases","label":"Irregular menses","text":"Phenotype: Irregular menses
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0198
N cases: 17228
N controls: 179322"}
{"pvalue":0.0815,"sign":1,"group":"N14: Genitourinary system diseases","label":"Excessive, frequent and irregular menstruation","text":"Phenotype: Excessive, frequent and irregular menstruation
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0815
N cases: 36824
N controls: 107564"}
{"pvalue":0.241,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Unspecified nephritic syndrome","text":"Phenotype: Unspecified nephritic syndrome
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.241
N cases: 584
N controls: 371635"}
{"pvalue":0.495,"sign":1,"group":"N14: Genitourinary system diseases","label":"Nephrotic syndrome","text":"Phenotype: Nephrotic syndrome
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.495
N cases: 853
N controls: 371635"}
{"pvalue":0.24,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Neuromuscular dysfunction of bladder","text":"Phenotype: Neuromuscular dysfunction of bladder
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.24
N cases: 2618
N controls: 328001"}
{"pvalue":0.0772,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other obstructive and reflux uropathy","text":"Phenotype: Other obstructive and reflux uropathy
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0772
N cases: 3832
N controls: 338942"}
{"pvalue":0.176,"sign":1,"group":"N14: Genitourinary system diseases","label":"Oligomenorrhoea","text":"Phenotype: Oligomenorrhoea
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.176
N cases: 1065
N controls: 107564"}
{"pvalue":0.0463,"sign":1,"group":"N14: Genitourinary system diseases","label":"Orchitis and epididymitis","text":"Phenotype: Orchitis and epididymitis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0463
N cases: 2688
N controls: 119297"}
{"pvalue":0.464,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other disorders of bladder","text":"Phenotype: Other disorders of bladder
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.464
N cases: 3435
N controls: 328001"}
{"pvalue":0.682,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Other disorders of male genital organs","text":"Phenotype: Other disorders of male genital organs
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.682
N cases: 936
N controls: 119297"}
{"pvalue":0.62,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Other specified disorders of kidney and ureter","text":"Phenotype: Other specified disorders of kidney and ureter
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.62
N cases: 875
N controls: 373761"}
{"pvalue":0.00967,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other female pelvic inflammatory diseases","text":"Phenotype: Other female pelvic inflammatory diseases
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00967
N cases: 5117
N controls: 188295"}
{"pvalue":0.775,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other inflammation of vagina/vulva","text":"Phenotype: Other inflammation of vagina/vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.775
N cases: 1013
N controls: 188295"}
{"pvalue":0.975,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other noninflammatory disorders of cervix uteri","text":"Phenotype: Other noninflammatory disorders of cervix uteri
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.975
N cases: 1426
N controls: 107564"}
{"pvalue":0.654,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament","text":"Phenotype: Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.654
N cases: 778
N controls: 107564"}
{"pvalue":0.583,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other noninflammatory disorders of uterus, except cervix","text":"Phenotype: Other noninflammatory disorders of uterus, except cervix
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.583
N cases: 8752
N controls: 107564"}
{"pvalue":0.949,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Other noninflammatory disorders of vagina","text":"Phenotype: Other noninflammatory disorders of vagina
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.949
N cases: 2358
N controls: 107564"}
{"pvalue":0.0573,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other noninflammatory disorders of vulva and perineum","text":"Phenotype: Other noninflammatory disorders of vulva and perineum
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0573
N cases: 2660
N controls: 107564"}
{"pvalue":0.883,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other disorders of penis","text":"Phenotype: Other disorders of penis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.883
N cases: 2643
N controls: 119297"}
{"pvalue":0.684,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Ovarian hyperstimulation (induction)","text":"Phenotype: Ovarian hyperstimulation (induction)
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.684
N cases: 436
N controls: 197728"}
{"pvalue":0.0958,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Torsion of ovary, ovarian pedicle and fallopian tube","text":"Phenotype: Torsion of ovary, ovarian pedicle and fallopian tube
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0958
N cases: 642
N controls: 107564"}
{"pvalue":0.0123,"sign":1,"group":"N14: Genitourinary system diseases","label":"Ovarian cyst","text":"Phenotype: Ovarian cyst
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0123
N cases: 20750
N controls: 107564"}
{"pvalue":0.512,"sign":1,"group":"N14: Genitourinary system diseases","label":"Redundant prepuce, phimosis and paraphimosis","text":"Phenotype: Redundant prepuce, phimosis and paraphimosis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.512
N cases: 6859
N controls: 119297"}
{"pvalue":0.778,"sign":1,"group":"N14: Genitourinary system diseases","label":"Polyp of the female genital tract","text":"Phenotype: Polyp of the female genital tract
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.778
N cases: 14324
N controls: 107564"}
{"pvalue":0.653,"sign":1,"group":"N14: Genitourinary system diseases","label":"Postmenopausal atrophic vaginitis","text":"Phenotype: Postmenopausal atrophic vaginitis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.653
N cases: 2534
N controls: 107564"}
{"pvalue":0.73,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Postmenopausal bleeding","text":"Phenotype: Postmenopausal bleeding
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.73
N cases: 11582
N controls: 107564"}
{"pvalue":0.878,"sign":1,"group":"N14: Genitourinary system diseases","label":"Premenstrual syndrome","text":"Phenotype: Premenstrual syndrome
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.878
N cases: 247
N controls: 107564"}
{"pvalue":0.0743,"sign":1,"group":"N14: Genitourinary system diseases","label":"Prolapse and hernia of ovary and fallopian tube","text":"Phenotype: Prolapse and hernia of ovary and fallopian tube
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0743
N cases: 1157
N controls: 107564"}
{"pvalue":0.479,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other disorders of prostate","text":"Phenotype: Other disorders of prostate
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.479
N cases: 991
N controls: 119297"}
{"pvalue":0.384,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Inflammatory diseases of prostate (prostatitis)","text":"Phenotype: Inflammatory diseases of prostate (prostatitis)
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.384
N cases: 3760
N controls: 119297"}
{"pvalue":0.762,"sign":1,"group":"N14: Genitourinary system diseases","label":"Hyperplasia of prostate","text":"Phenotype: Hyperplasia of prostate
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.762
N cases: 30066
N controls: 119297"}
{"pvalue":0.766,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Acute tubulo-interstitial nephritis","text":"Phenotype: Acute tubulo-interstitial nephritis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.766
N cases: 23912
N controls: 338942"}
{"pvalue":0.065,"sign":1,"group":"N14: Genitourinary system diseases","label":"Recurrent and persistent haematuria","text":"Phenotype: Recurrent and persistent haematuria
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.065
N cases: 216
N controls: 371635"}
{"pvalue":0.443,"sign":1,"group":"N14: Genitourinary system diseases","label":"Unspecified renal colic","text":"Phenotype: Unspecified renal colic
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.443
N cases: 152
N controls: 366693"}
{"pvalue":0.245,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Renal tubulo-interstitial diseases","text":"Phenotype: Renal tubulo-interstitial diseases
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.245
N cases: 38335
N controls: 338942"}
{"pvalue":0.569,"sign":1,"group":"N14: Genitourinary system diseases","label":"Renal tubulo-interstitial disorders in diseases classified elsewhere","text":"Phenotype: Renal tubulo-interstitial disorders in diseases classified elsewhere
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.569
N cases: 246
N controls: 338942"}
{"pvalue":0.696,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Other renal tubulo-interstitial diseases","text":"Phenotype: Other renal tubulo-interstitial diseases
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.696
N cases: 663
N controls: 338942"}
{"pvalue":0.179,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Renal failure","text":"Phenotype: Renal failure
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.179
N cases: 14100
N controls: 363177"}
{"pvalue":0.802,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Unspecified kidney failure","text":"Phenotype: Unspecified kidney failure
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.802
N cases: 2577
N controls: 363177"}
{"pvalue":0.00901,"sign":1,"group":"N14: Genitourinary system diseases","label":"Salpingitis and oophoritis","text":"Phenotype: Salpingitis and oophoritis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.00901
N cases: 5768
N controls: 188295"}
{"pvalue":0.707,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Spermatocele","text":"Phenotype: Spermatocele
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.707
N cases: 2214
N controls: 119297"}
{"pvalue":0.961,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Torsion of testis","text":"Phenotype: Torsion of testis
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.961
N cases: 529
N controls: 119297"}
{"pvalue":0.852,"sign":1,"group":"N14: Genitourinary system diseases","label":"Tubulo-interstitial nephritis, not specified as acute or chronic","text":"Phenotype: Tubulo-interstitial nephritis, not specified as acute or chronic
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.852
N cases: 2110
N controls: 338942"}
{"pvalue":0.157,"sign":1,"group":"N14: Genitourinary system diseases","label":"Ulcer of vagina/vulva","text":"Phenotype: Ulcer of vagina/vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.157
N cases: 560
N controls: 188295"}
{"pvalue":0.916,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Unspecified contracted kidney","text":"Phenotype: Unspecified contracted kidney
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.916
N cases: 142
N controls: 373761"}
{"pvalue":0.183,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Urethral stricture","text":"Phenotype: Urethral stricture
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.183
N cases: 1597
N controls: 328001"}
{"pvalue":0.151,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other disorders of urethra and urinary system","text":"Phenotype: Other disorders of urethra and urinary system
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.151
N cases: 32905
N controls: 328001"}
{"pvalue":0.795,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Urethritis and urethral syndrome","text":"Phenotype: Urethritis and urethral syndrome
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.795
N cases: 616
N controls: 328001"}
{"pvalue":0.345,"sign":1,"group":"N14: Genitourinary system diseases","label":"Other diseases of urinary system","text":"Phenotype: Other diseases of urinary system
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.345
N cases: 49276
N controls: 328001"}
{"pvalue":0.137,"sign":-1,"group":"N14: Genitourinary system diseases","label":"Uterine polyps","text":"Phenotype: Uterine polyps
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.137
N cases: 2871
N controls: 107564"}
{"pvalue":0.965,"sign":1,"group":"N14: Genitourinary system diseases","label":"All dysplastic lesions of the vagina","text":"Phenotype: All dysplastic lesions of the vagina
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.965
N cases: 641
N controls: 210229"}
{"pvalue":0.445,"sign":-1,"group":"N14: Genitourinary system diseases","label":"HSIL lesion of the vagina","text":"Phenotype: HSIL lesion of the vagina
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.445
N cases: 335
N controls: 210535"}
{"pvalue":0.377,"sign":1,"group":"N14: Genitourinary system diseases","label":"LSIL lesion of the vagina","text":"Phenotype: LSIL lesion of the vagina
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.377
N cases: 344
N controls: 210526"}
{"pvalue":0.125,"sign":1,"group":"N14: Genitourinary system diseases","label":"Vaginitis/vulvovaginitis/vulvitis/abscess of vulva","text":"Phenotype: Vaginitis/vulvovaginitis/vulvitis/abscess of vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.125
N cases: 4648
N controls: 188295"}
{"pvalue":0.478,"sign":1,"group":"N14: Genitourinary system diseases","label":"All dysplastic lesions of the vulva","text":"Phenotype: All dysplastic lesions of the vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.478
N cases: 1118
N controls: 209752"}
{"pvalue":0.271,"sign":1,"group":"N14: Genitourinary system diseases","label":"HSIL lesion of the vulva","text":"Phenotype: HSIL lesion of the vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.271
N cases: 391
N controls: 210479"}
{"pvalue":0.665,"sign":1,"group":"N14: Genitourinary system diseases","label":"LSIL lesion of the vulva","text":"Phenotype: LSIL lesion of the vulva
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.665
N cases: 770
N controls: 210100"}
{"pvalue":0.0606,"sign":1,"group":"N14: Genitourinary system diseases","label":"Vulvovaginal ulceration/inflammation in other diseases","text":"Phenotype: Vulvovaginal ulceration/inflammation in other diseases
Category: N14: Genitourinary system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0606
N cases: 1494
N controls: 188295"}
{"pvalue":0.63,"sign":1,"group":"M13: Musculoskeletal system diseases","label":"Osteonecrosis due to drugs","text":"Phenotype: Osteonecrosis due to drugs
Category: M13: Musculoskeletal system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.63
N cases: 264
N controls: 377013"}
{"pvalue":0.287,"sign":1,"group":"G6: Nervous system diseases","label":"Other drug-induced secondary parkinsonism","text":"Phenotype: Other drug-induced secondary parkinsonism
Category: G6: Nervous system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.287
N cases: 234
N controls: 377043"}
{"pvalue":0.31,"sign":1,"group":"I9: Circulatory system diseases","label":"Phlebitis and thrombophlebitis of lower extremities, unspecified, drug-induced","text":"Phenotype: Phlebitis and thrombophlebitis of lower extremities, unspecified, drug-induced
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.31
N cases: 253
N controls: 377024"}
{"pvalue":0.252,"sign":-1,"group":"I9: Circulatory system diseases","label":"Phlebitis and thrombophlebitis of other deep vessels of lower extremities, drug-induced","text":"Phenotype: Phlebitis and thrombophlebitis of other deep vessels of lower extremities, drug-induced
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.252
N cases: 86
N controls: 377191"}
{"pvalue":0.678,"sign":1,"group":"I9: Circulatory system diseases","label":"Phlebitis and thrombophlebitis of superficial vessels of lower extremities, drug-induced","text":"Phenotype: Phlebitis and thrombophlebitis of superficial vessels of lower extremities, drug-induced
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.678
N cases: 83
N controls: 377194"}
{"pvalue":0.173,"sign":-1,"group":"L12: Skin and subcutaneous tissue diseases","label":"Psoriasis (vulgaris), strict definition","text":"Phenotype: Psoriasis (vulgaris), strict definition
Category: L12: Skin and subcutaneous tissue diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.173
N cases: 679
N controls: 364071"}
{"pvalue":0.6,"sign":-1,"group":"Q17: Congenital diseases","label":"Ankyloglossia","text":"Phenotype: Ankyloglossia
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.6
N cases: 365
N controls: 376912"}
{"pvalue":0.0542,"sign":-1,"group":"Q17: Congenital diseases","label":"Atrial septal defect","text":"Phenotype: Atrial septal defect
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0542
N cases: 1070
N controls: 373043"}
{"pvalue":0.34,"sign":-1,"group":"Q17: Congenital diseases","label":"Atrioventricular septal defect","text":"Phenotype: Atrioventricular septal defect
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.34
N cases: 108
N controls: 377169"}
{"pvalue":0.755,"sign":-1,"group":"Q17: Congenital diseases","label":"Balanced rearrangements and structural markers, not elsewhere classified","text":"Phenotype: Balanced rearrangements and structural markers, not elsewhere classified
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.755
N cases: 92
N controls: 376808"}
{"pvalue":0.528,"sign":-1,"group":"Q17: Congenital diseases","label":"Chromosomal abnormalities, not elsewhere classified","text":"Phenotype: Chromosomal abnormalities, not elsewhere classified
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.528
N cases: 469
N controls: 376808"}
{"pvalue":0.698,"sign":1,"group":"Q17: Congenital diseases","label":"Caries in Clefts patients , including avohilmo","text":"Phenotype: Caries in Clefts patients , including avohilmo
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.698
N cases: 230
N controls: 377047"}
{"pvalue":0.1,"sign":1,"group":"Q17: Congenital diseases","label":"Cleft hard palate NOS","text":"Phenotype: Cleft hard palate NOS
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.1
N cases: 125
N controls: 376605"}
{"pvalue":0.0776,"sign":1,"group":"Q17: Congenital diseases","label":"Cleft lip and palate","text":"Phenotype: Cleft lip and palate
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0776
N cases: 148
N controls: 376582"}
{"pvalue":0.294,"sign":1,"group":"Q17: Congenital diseases","label":"Cleft lip, lip and palate or palate","text":"Phenotype: Cleft lip, lip and palate or palate
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.294
N cases: 444
N controls: 376833"}
{"pvalue":0.742,"sign":1,"group":"Q17: Congenital diseases","label":"Cleft palate","text":"Phenotype: Cleft palate
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.742
N cases: 290
N controls: 376833"}
{"pvalue":0.0412,"sign":-1,"group":"Q17: Congenital diseases","label":"Complex cardiac defects","text":"Phenotype: Complex cardiac defects
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0412
N cases: 165
N controls: 377112"}
{"pvalue":0.231,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital deformities of feet","text":"Phenotype: Congenital deformities of feet
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.231
N cases: 674
N controls: 374712"}
{"pvalue":0.575,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital deformities of hip","text":"Phenotype: Congenital deformities of hip
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.575
N cases: 451
N controls: 374712"}
{"pvalue":0.373,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital ichthyosis","text":"Phenotype: Congenital ichthyosis
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.373
N cases: 89
N controls: 374727"}
{"pvalue":0.64,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital lens malformations","text":"Phenotype: Congenital lens malformations
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.64
N cases: 123
N controls: 375350"}
{"pvalue":0.836,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of anterior segment of eye","text":"Phenotype: Congenital malformations of anterior segment of eye
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.836
N cases: 222
N controls: 375350"}
{"pvalue":0.218,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital malformations of breast","text":"Phenotype: Congenital malformations of breast
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.218
N cases: 420
N controls: 374727"}
{"pvalue":0.926,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital malformations of cardiac chambers and connections","text":"Phenotype: Congenital malformations of cardiac chambers and connections
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.926
N cases: 168
N controls: 373043"}
{"pvalue":0.548,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of the circulatory system","text":"Phenotype: Congenital malformations of the circulatory system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.548
N cases: 4234
N controls: 373043"}
{"pvalue":0.00976,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital malformations and deformations of the musculoskeletal system","text":"Phenotype: Congenital malformations and deformations of the musculoskeletal system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00976
N cases: 2565
N controls: 374712"}
{"pvalue":0.324,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital malformations of ear causing impairment of hearing","text":"Phenotype: Congenital malformations of ear causing impairment of hearing
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.324
N cases: 102
N controls: 375350"}
{"pvalue":0.251,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of eye, ear, face and neck","text":"Phenotype: Congenital malformations of eye, ear, face and neck
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.251
N cases: 1927
N controls: 375350"}
{"pvalue":0.24,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of eyelid, lacrimal apparatus and orbit","text":"Phenotype: Congenital malformations of eyelid, lacrimal apparatus and orbit
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.24
N cases: 219
N controls: 375350"}
{"pvalue":0.571,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital malformations of gallbladder, bile ducts and liver","text":"Phenotype: Congenital malformations of gallbladder, bile ducts and liver
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.571
N cases: 222
N controls: 376152"}
{"pvalue":0.616,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of genital organs","text":"Phenotype: Congenital malformations of genital organs
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.616
N cases: 2867
N controls: 374410"}
{"pvalue":0.877,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital malformations of great arteries","text":"Phenotype: Congenital malformations of great arteries
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.877
N cases: 579
N controls: 373043"}
{"pvalue":0.138,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital malformations of the musculoskeletal system, not elsewhere classified","text":"Phenotype: Congenital malformations of the musculoskeletal system, not elsewhere classified
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.138
N cases: 354
N controls: 374712"}
{"pvalue":0.612,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of the nervous system","text":"Phenotype: Congenital malformations of the nervous system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.612
N cases: 563
N controls: 376714"}
{"pvalue":0.28,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of oesophagus","text":"Phenotype: Congenital malformations of oesophagus
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.28
N cases: 110
N controls: 376152"}
{"pvalue":0.32,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of ovaries, fallopian tubes and broad ligaments","text":"Phenotype: Congenital malformations of ovaries, fallopian tubes and broad ligaments
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.32
N cases: 1615
N controls: 374410"}
{"pvalue":0.749,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of posterior segment of eye","text":"Phenotype: Congenital malformations of posterior segment of eye
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.749
N cases: 134
N controls: 375350"}
{"pvalue":0.138,"sign":-1,"group":"Q17: Congenital diseases","label":"Congenital malformations of pulmonary and tricuspid valves","text":"Phenotype: Congenital malformations of pulmonary and tricuspid valves
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.138
N cases: 210
N controls: 373043"}
{"pvalue":0.0713,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of the respiratory system","text":"Phenotype: Congenital malformations of the respiratory system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0713
N cases: 454
N controls: 376823"}
{"pvalue":0.592,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of spine and bony thorax","text":"Phenotype: Congenital malformations of spine and bony thorax
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.592
N cases: 152
N controls: 374712"}
{"pvalue":0.264,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of trachea and bronchus","text":"Phenotype: Congenital malformations of trachea and bronchus
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.264
N cases: 253
N controls: 376823"}
{"pvalue":0.251,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of the urinary system","text":"Phenotype: Congenital malformations of the urinary system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.251
N cases: 1569
N controls: 375708"}
{"pvalue":0.867,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital malformations of uterus and cervix","text":"Phenotype: Congenital malformations of uterus and cervix
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.867
N cases: 574
N controls: 374410"}
{"pvalue":0.928,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital musculoskeletal deformities of head, face, spine and chest","text":"Phenotype: Congenital musculoskeletal deformities of head, face, spine and chest
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.928
N cases: 316
N controls: 374712"}
{"pvalue":0.55,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital obstructive defects of renal pelvis and congenital malformations of ureter","text":"Phenotype: Congenital obstructive defects of renal pelvis and congenital malformations of ureter
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.55
N cases: 491
N controls: 375708"}
{"pvalue":0.121,"sign":-1,"group":"Q17: Congenital diseases","label":"Conotruncal defects","text":"Phenotype: Conotruncal defects
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.121
N cases: 375
N controls: 376902"}
{"pvalue":0.755,"sign":-1,"group":"Q17: Congenital diseases","label":"Craniosynostosis EXCLUDE syndromes","text":"Phenotype: Craniosynostosis EXCLUDE syndromes
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.755
N cases: 714
N controls: 376563"}
{"pvalue":0.929,"sign":-1,"group":"Q17: Congenital diseases","label":"Cystic kidney disease","text":"Phenotype: Cystic kidney disease
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.929
N cases: 865
N controls: 375708"}
{"pvalue":0.949,"sign":1,"group":"Q17: Congenital diseases","label":"Down's syndrome","text":"Phenotype: Down's syndrome
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.949
N cases: 94
N controls: 376808"}
{"pvalue":0.515,"sign":-1,"group":"Q17: Congenital diseases","label":"Ehlers-Danlos syndrome","text":"Phenotype: Ehlers-Danlos syndrome
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.515
N cases: 236
N controls: 377041"}
{"pvalue":0.823,"sign":-1,"group":"Q17: Congenital diseases","label":"Hypospadias","text":"Phenotype: Hypospadias
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.823
N cases: 103
N controls: 374410"}
{"pvalue":0.571,"sign":1,"group":"Q17: Congenital diseases","label":"Congenital deformities of hip","text":"Phenotype: Congenital deformities of hip
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.571
N cases: 2891
N controls: 374386"}
{"pvalue":0.296,"sign":1,"group":"Q17: Congenital diseases","label":"Left ventricular outflow tract obstruction, narrow definition","text":"Phenotype: Left ventricular outflow tract obstruction, narrow definition
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.296
N cases: 1243
N controls: 376034"}
{"pvalue":0.197,"sign":-1,"group":"Q17: Congenital diseases","label":"Other chromosome abnormalities, not elsewhere classified","text":"Phenotype: Other chromosome abnormalities, not elsewhere classified
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.197
N cases: 102
N controls: 376808"}
{"pvalue":0.831,"sign":-1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of brain","text":"Phenotype: Other congenital malformations of brain
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.831
N cases: 123
N controls: 376714"}
{"pvalue":0.0519,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of circulatory system","text":"Phenotype: Other congenital malformations of circulatory system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.0519
N cases: 647
N controls: 373043"}
{"pvalue":0.79,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of the digestive system","text":"Phenotype: Other congenital malformations of the digestive system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.79
N cases: 1125
N controls: 376152"}
{"pvalue":0.614,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of ear","text":"Phenotype: Other congenital malformations of ear
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.614
N cases: 363
N controls: 375350"}
{"pvalue":0.488,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of face and neck","text":"Phenotype: Other congenital malformations of face and neck
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.488
N cases: 798
N controls: 375350"}
{"pvalue":0.615,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of female genitalia","text":"Phenotype: Other congenital malformations of female genitalia
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.615
N cases: 234
N controls: 374410"}
{"pvalue":0.829,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations","text":"Phenotype: Other congenital malformations
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.829
N cases: 2550
N controls: 374727"}
{"pvalue":0.465,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of heart","text":"Phenotype: Other congenital malformations of heart
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.465
N cases: 163
N controls: 373043"}
{"pvalue":0.291,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of intestine","text":"Phenotype: Other congenital malformations of intestine
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.291
N cases: 217
N controls: 376152"}
{"pvalue":0.846,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of kidney","text":"Phenotype: Other congenital malformations of kidney
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.846
N cases: 94
N controls: 375708"}
{"pvalue":0.103,"sign":-1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of limb(s)","text":"Phenotype: Other congenital malformations of limb(s)
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.103
N cases: 203
N controls: 374712"}
{"pvalue":0.583,"sign":-1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of male genital organs","text":"Phenotype: Other congenital malformations of male genital organs
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.583
N cases: 161
N controls: 374410"}
{"pvalue":0.817,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of nervous system","text":"Phenotype: Other congenital malformations of nervous system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.817
N cases: 239
N controls: 376714"}
{"pvalue":0.88,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations, not elsewhere classified","text":"Phenotype: Other congenital malformations, not elsewhere classified
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.88
N cases: 212
N controls: 374727"}
{"pvalue":0.238,"sign":-1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of peripheral vascular system","text":"Phenotype: Other congenital malformations of peripheral vascular system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.238
N cases: 319
N controls: 373043"}
{"pvalue":0.295,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of skin","text":"Phenotype: Other congenital malformations of skin
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.295
N cases: 1129
N controls: 374727"}
{"pvalue":0.934,"sign":-1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of skull and face bones","text":"Phenotype: Other congenital malformations of skull and face bones
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.934
N cases: 85
N controls: 374712"}
{"pvalue":0.886,"sign":-1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of tongue, mouth and pharynx","text":"Phenotype: Other congenital malformations of tongue, mouth and pharynx
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.886
N cases: 327
N controls: 376152"}
{"pvalue":0.625,"sign":-1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of upper alimentary tract","text":"Phenotype: Other congenital malformations of upper alimentary tract
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.625
N cases: 175
N controls: 376152"}
{"pvalue":0.262,"sign":1,"group":"Q17: Congenital diseases","label":"Other congenital malformations of urinary system","text":"Phenotype: Other congenital malformations of urinary system
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.262
N cases: 121
N controls: 375708"}
{"pvalue":0.851,"sign":-1,"group":"Q17: Congenital diseases","label":"Other congenital musculoskeletal deformities","text":"Phenotype: Other congenital musculoskeletal deformities
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.851
N cases: 85
N controls: 374712"}
{"pvalue":0.13,"sign":-1,"group":"Q17: Congenital diseases","label":"Other osteochondrodysplasias","text":"Phenotype: Other osteochondrodysplasias
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.13
N cases: 213
N controls: 374712"}
{"pvalue":0.911,"sign":1,"group":"Q17: Congenital diseases","label":"Other specified congenital malformation syndromes affecting multiple systems","text":"Phenotype: Other specified congenital malformation syndromes affecting multiple systems
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.911
N cases: 441
N controls: 374727"}
{"pvalue":0.8,"sign":-1,"group":"Q17: Congenital diseases","label":"Phakomatoses, not elsewhere classified","text":"Phenotype: Phakomatoses, not elsewhere classified
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.8
N cases: 284
N controls: 374727"}
{"pvalue":0.217,"sign":1,"group":"Q17: Congenital diseases","label":"Renal agenesis and other reduction defects of kidney","text":"Phenotype: Renal agenesis and other reduction defects of kidney
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.217
N cases: 129
N controls: 375708"}
{"pvalue":0.288,"sign":-1,"group":"Q17: Congenital diseases","label":"Right ventricular outflow tract obstruction","text":"Phenotype: Right ventricular outflow tract obstruction
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.288
N cases: 225
N controls: 377052"}
{"pvalue":0.449,"sign":-1,"group":"Q17: Congenital diseases","label":"Septal defects","text":"Phenotype: Septal defects
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.449
N cases: 1744
N controls: 375533"}
{"pvalue":0.0466,"sign":-1,"group":"Q17: Congenital diseases","label":"Undescended testicle","text":"Phenotype: Undescended testicle
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0466
N cases: 261
N controls: 374410"}
{"pvalue":0.323,"sign":1,"group":"Q17: Congenital diseases","label":"Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly","text":"Phenotype: Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
Category: Q17: Congenital diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.323
N cases: 4984
N controls: 372293"}
{"pvalue":0.989,"sign":1,"group":"F5: Mental and behavioural disorders","label":"Use of hypnotics and sedatives","text":"Phenotype: Use of hypnotics and sedatives
Category: F5: Mental and behavioural disorders
rsID: rs2228145-C
Direction: 1
p-value: 0.989
N cases: 65814
N controls: 311463"}
{"pvalue":0.00771,"sign":-1,"group":"I9: Circulatory system diseases","label":"Statin medication","text":"Phenotype: Statin medication
Category: I9: Circulatory system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.00771
N cases: 127169
N controls: 250108"}
{"pvalue":0.638,"sign":-1,"group":"AB1: Infectious diseases","label":"Respiratory tuberculosis","text":"Phenotype: Respiratory tuberculosis
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.638
N cases: 1793
N controls: 374922"}
{"pvalue":0.677,"sign":1,"group":"K11: Digestive system diseases","label":"Temporomandibular joint disorders","text":"Phenotype: Temporomandibular joint disorders
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.677
N cases: 5668
N controls: 205355"}
{"pvalue":0.798,"sign":1,"group":"K11: Digestive system diseases","label":"Temporomandibular joint disorders, including avohilmo","text":"Phenotype: Temporomandibular joint disorders, including avohilmo
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: 1
p-value: 0.798
N cases: 13282
N controls: 363995"}
{"pvalue":0.105,"sign":-1,"group":"K11: Digestive system diseases","label":"Tongue abnormality","text":"Phenotype: Tongue abnormality
Category: K11: Digestive system diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.105
N cases: 1574
N controls: 375703"}
{"pvalue":0.0618,"sign":-1,"group":"E4: Endocrine, nutritional and metabolic diseases","label":"Vitamin deficiency","text":"Phenotype: Vitamin deficiency
Category: E4: Endocrine, nutritional and metabolic diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.0618
N cases: 1334
N controls: 354812"}
{"pvalue":0.567,"sign":-1,"group":"H7: Eye and adnexa diseases","label":"Wet age-related macular degeneration","text":"Phenotype: Wet age-related macular degeneration
Category: H7: Eye and adnexa diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.567
N cases: 4848
N controls: 252277"}
{"pvalue":0.617,"sign":-1,"group":"AB1: Infectious diseases","label":"Enteritis due to Yersinia enterocolitica","text":"Phenotype: Enteritis due to Yersinia enterocolitica
Category: AB1: Infectious diseases
rsID: rs2228145-C
Direction: -1
p-value: 0.617
N cases: 127
N controls: 371656"}