Package: tryx Title: MR-TRYX (treasure your exceptions) Version: 0.2.1 Authors@R: c( person("Gibran", "Hemani", , "g.hemani@bristol.ac.uk", role = c("aut", "cre")), person("Yoonsu", "Cho", , "yoonsu.cho@bristol.ac.uk", role = "aut") ) Description: Heterogeneity in MR analyses can arise due to horizontal pleiotropy. This package uses MR-Base to identify possible traits that can explain the heterogeneity, with a view to identifying novel putative associations, and adjusting for their influences to reduce heterogeneity and improve power. License: MIT + file LICENSE URL: https://mrcieu.r-universe.dev/tryx, https://explodecomputer.github.io/tryx/, https://github.com/explodecomputer/tryx BugReports: https://github.com/explodecomputer/tryx/issues Depends: R (>= 4.1.0) Imports: dplyr, ggplot2, ggrepel, glmnet, magrittr, R6, RadialMR, tibble, tidyr, TwoSampleMR Suggests: igraph, knitr, rmarkdown, simulateGP, testthat VignetteBuilder: knitr Remotes: explodecomputer/simulateGP, MRCIEU/TwoSampleMR, WSpiller/RadialMR Config/roxygen2/version: 8.1.0 Encoding: UTF-8 Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libssl-dev Repository: https://mrcieu.r-universe.dev Date/Publication: 2026-09-26 16:12:57 UTC RemoteUrl: https://github.com/explodecomputer/tryx RemoteRef: refs/pull/26/head RemoteSha: d927e26f3919ce35e125738549fb87470999f3df NeedsCompilation: no Packaged: 2026-10-20 12:21:35 UTC; root Author: Gibran Hemani [aut, cre], Yoonsu Cho [aut] Maintainer: Gibran Hemani