Package: MRTool 0.0.0.9000

Anne-Sophie Kieslinger

MRTool: Simulating Data for Mendelian Randomization Scenarios Based on Genotype Data

This package can be used to simulate data in R for Mendelian Randomization scenarios including confounder, exposure and outcome. Recommended MR package is MendelianRandomization.

Authors:Anne-Sophie Kieslinger [aut, cre], Carl Beuchel [aut]

MRTool_0.0.0.9000.tar.gz
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MRTool.pdf |MRTool.html✨
MRTool/json (API)

# Install 'MRTool' in R:

install.packages('MRTool', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/askieslinger/mrtool/issues

On CRAN:

1.70 score 1 stars 7 exports 91 dependencies

Last updated 5 years agofrom:eea664f1c3. Checks:ERROR: 1 WARNING: 6. Indexed: no.

Target	Result	Date
Doc / Vignettes	FAIL	Oct 26 2024
R-4.5-win	WARNING	Oct 26 2024
R-4.5-linux	WARNING	Oct 26 2024
R-4.4-win	WARNING	Oct 26 2024
R-4.4-mac	WARNING	Oct 26 2024
R-4.3-win	WARNING	Oct 26 2024
R-4.3-mac	WARNING	Oct 26 2024

Exports:cal_betas CreateMRInputObject get_corrs SetMRParams sim_and_mr SimulateMRData transform_results

Dependencies:arrangements askpass backports base64enc broom bslib cachem cli codetools colorspace cpp11 crosstalk curl data.table DEoptimR digest dplyr evaluate fansi farver fastmap fontawesome foreach fs generics ggplot2 glmnet glue gmp gtable highr htmltools htmlwidgets httr isoband iterators iterpc jquerylib jsonlite knitr labeling later lattice lazyeval lifecycle magrittr MASS Matrix MatrixModels memoise MendelianRandomization mgcv mime munsell nlme numDeriv openssl pillar pkgconfig plotly promises purrr quantreg R6 rappdirs RColorBrewer Rcpp RcppArmadillo RcppEigen rjson rlang rmarkdown robustbase sass scales shape SparseM stringi stringr survival sys tibble tidyr tidyselect tinytex utf8 vctrs viridisLite withr xfun yaml

Vignettes and/or manual for this package failed to build, some documents may be unavailable. Please inspect thebuild logs for more information.

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
calculates betacoefficients from explained variances	cal_betas
Create MRInput Object	CreateMRInputObject
calculate correlation for a datatable of snps	get_corrs
MRTool: A package to simulate data for mendelian randomization	MRTool
Set MR Parameters (betacoefficients)	SetMRParams
Simulate U,X and Y and run MR on them	sim_and_mr
Simulate MR Data	SimulateMRData
Transform result of iterations of simulation and MR	transform_results