1. alspac::current
    Current data
  2. alspac::sources
  3. BESIDEMR::AMD_HDL
    Effect of HDL choesterol on age-related macular degeneration (AMD)
  4. BWMR::ExampleData
    Example Mendelian randomization genotype summary level dataset
  5. CheckSumStats::ara_test_dat
    A example dataset of genetic summary data for arachidonic acid
  6. CheckSumStats::charge_top_hits
    GWAS top hits for arachidonic acid in the CHARGE consortium
  7. CheckSumStats::charge_top_hits_cleaned
    GWAS top hits for arachidonic acid in the CHARGE consortium after post-GWAS cleaning
  8. CheckSumStats::glioma_test_dat
    A example dataset of genetic summary data
  9. CheckSumStats::refdat_1000G_superpops
    A dataset of reference allele frequencies from 1000 genomes superpopulations
  10. CIVMR::ADNI
    ADNI Data.
    data.frame|491 x 4
  11. CIVMR::G
  12. CIVMR::MR
    data.frame|500 x 8
  13. CIVMR::X
  14. CIVMR::Y
  15. CIVMR::Z
  16. CIVMR::simulation
    simulation Data.
    data.frame|500 x 7
  17. ColliderBias::testData
    Sample simulated genome-wide association study (GWAS) summary statisitcs for analysis.
  18. EpiViz::EpiViz_data1
    Example data: Mendelian randomization results from an analysis of BMI measured in European men and women and 123 metabolites
  19. EpiViz::EpiViz_data2
    Example data: Mendelian randomization results from an analysis of BMI measured in European men and 123 metabolites
  20. EpiViz::EpiViz_data3
    Example data: Mendelian randomization results from an analysis of BMI measured in European women and 123 metabolites
  21. geni.plots::genes_pos_b37
  22. geni.plots::genes_pos_b38
  23. geni.plots::geni_test_manhattan
    GENI plots test data for the Manhattan plot
  24. geni.plots::geni_test_phewas
    GENI plots test data for the PheWAS plot
  25. geni.plots::geni_test_region
    GENI plots test data for the regional plot
  26. geni.plots::geni_test_stack_region
    GENI plots test data for the stacked regional plot
  27. geni.plots::recomb_b37
  28. geni.plots::recomb_b38
  29. gsmr::gsmr_data
  30. gsmr::ldrho
  31. gsmr::snp_coeff
  32. gsmr::snp_coeff_id
  33. gsmr2::gsmr_data
  34. gsmr2::ldrho
  35. gsmr2::snp_coeff
  36. gsmr2::snp_coeff_id
  37. GWASBrewer::AF
  38. GWASBrewer::ld_mat_list
  39. GWASBrewer::snpdata
  40. GwasDataImport::build_ref
  41. GwasDataImport::mart36
  42. GwasDataImport::mart37
  43. GwasDataImport::mart38
  44. hdi::riboflavin
    Riboflavin data set
    data.frame|71 x 2
  45. indexevent::testData
    Simulated effects on incidence and prognosis
  46. ivmodel::card.data
    Card (1995) Data
  47. ivmodel::icu.data
    Pseudo-data based on Branson and Keele (2020)
  48. metaboprep::ng_anno
    Nightingale Health metabolomics annotation data set
  49. midoc::bmi
    Child body mass index data
  50. mr.pivw::Bx_exp
    Example data
  51. mr.pivw::Bxse_exp
    Example data
  52. mr.pivw::By_exp
    Example data
  53. mr.pivw::Byse_exp
    Example data
  54. mr.raps::bmi.ais
    Effect of Body Mass Index (BMI) on Acute Ischemic Stroke (AIS)
  55. mr.raps::bmi.bmi
    "Effect" of Body Mass Index (BMI) on Body Mass Index (BMI)
  56. mr.raps::bmi.cad
    Effect of Body Mass Index (BMI) on Coronary Artery Disease (CAD)
  57. mr.raps::bmi.sbp
    Effect of Body Mass Index (BMI) on Systolic Blood Pressure (SBP)
  58. mr.raps::cad.bmi
    Effect of Coronary Artery Disease (CAD) on Body Mass Index (BMI) (To study reverse causality)
  59. mr.raps::cad.cad
    Effect of Coronary Artery Disease (BMI) on Coronary Artery Disease (CAD)
  60. mr.raps::crp.cad
    Effect of C-Reactive Protein on Coronary Artery Disease (CAD)
  61. mr.raps::lipid.cad
    Effect of blood lipids (LDL cholesterol, HDL cholesterol, Triglycerides) on Cardiovascular disease risk
  62. MRAPSS::C
  63. MRAPSS::MHC.SNPs
  64. MRAPSS::MRdat
  65. MRAPSS::Omega
  66. MRAPSS::w_hm3.snplist
    spec_tbl_df|1217311 x 3
  67. mrbayes::bmi_insulin
    Dataset from Richmond et. al 2017 investigating the association of BMI on insulin resistance
  68. mrbayes::dodata
    Dataset from Do et al., Nat Gen, 2013 containing summary level data on associations of genotypes with lipid traits and the risk of coronary heart diseases
  69. MRBEE::hapmap3
    HapMap3 and UKBB Genotype SNP Data
  70. MRchecks::test_data
  71. mrclust::DBP_CAD
    Genetic association data from diastolic blood pressure (DBP) and coronary artery disease (CAD) GWAS.
  72. mrclust::PP_CAD
    Genetic association data from pulse pressure (PP) and coronary artery disease (CAD) GWAS.
  73. mrclust::SBP_CAD
    Genetic association data from systolic blood pressure (SBP) and coronary artery disease (CAD) GWAS.
  74. MRcML::T2D_FG
  75. MRCorge::Alcohol_CAD
  76. MRCorge::BMI_CAD
  77. MRCorge::HDL_CAD
  78. MRCorge::Height_CognitivePerformance
  79. MRCorge::IGF1_Height
  80. MRCorge::LDL_CAD
  81. MRCorge::Urate_Gout
  82. MRCorge::VitaminD_CAD
  83. MrDAG::LBT2MD_data
    MrDAG data set: Lifestyle and behavioural exposures that might impact mental health phenotypes
    matrix|708 x 13
  84. MrDAG::MD2LBT_data
    MrDAG data set: Mental health phenotypes that might impact lifestyle and behavioural traits
    matrix|470 x 13
  85. MRInstruments::aries_mqtl
    Data frame of mQTLs from ARIES study
  86. MRInstruments::blueprint_monocyte_eqtl
    Data frame of eQTLs (monocyte cells) from the BLUEPRINT study
  87. MRInstruments::drug_interactions
    Drug interactions
  88. MRInstruments::gene_trials
    Drug trial information regarding target genes
  89. MRInstruments::gtex_eqtl
    Data frame of cis-eQTLs from GTEx study (version 6p)
  90. MRInstruments::gwas_catalog
    Data frame of GWAS significant SNPs obtained from the EBI GWAS catalog
  91. MRInstruments::metab_qtls
    Data frame of QTLs of metabolites
  92. MRInstruments::mrbase_instruments
    Data frame of GWAS significant SNPs obtained from the EBI GWAS catalog
  93. MRInstruments::proteomic_qtls
    Data frame of proteomic QTLs from Deming et al 2016
  94. MRMix::BMI15
  95. MRMix::MDD18
  96. MRMix::sumstats
  97. MRMix::sumstats_std
  98. MRPATH::bmi_t2d
    Effect of Body Mass Index (BMI) on Type-2 Diabetes (T2D)
  99. MRPATH::hdl_chd
    Effect of HDL Cholesterol (HDL-C) on Coronary Heart Disease (CHD)
  100. MRPC::MRPCtruth
    Graphs used as truth in simulation
  101. MRPC::data_GEUVADIS
    GEUVADIS data with 62 eQTL-gene sets
  102. MRPC::data_GEUVADIS_combined
    Combined genotype and gene expression data from 62 eQTL-gene sets in 373 Europeans from GEUVADIS
    matrix|373 x 194
  103. MRPC::data_examples
    Example data under simple and complex models
  104. MRPC::data_with_outliers
    Example data with outliers
  105. MRPC::data_without_outliers
    Example data without outliers
  106. MRPC::simu_data_M0
    Data for Model 0
  107. MRPC::simu_data_M1
    Data for Model 1
  108. MRPC::simu_data_M2
    Data for Model 2
  109. MRPC::simu_data_M3
    Data for Model 3
  110. MRPC::simu_data_M4
    Data for Model 4
  111. MRPC::simu_data_layered
    Data for the layered model
  112. MRPC::simu_data_multiparent
    Data for the multiple-parent model
  113. MRPC::simu_data_starshaped
    Data for the star model
  114. MRPRESSO::SummaryStats
    Simulated toy dataset
  115. mrsensemakr::sim_data
    Simulated Data
  116. MVMR::rawdat_mvmr
    Raw multivariable MR summary data using lipid fractions as exposures and systolic blood pressure as an outcome.
  117. PPMR::Exampleindividual
    Individual level dataset
  118. PPMR::Examplesummary
    Summary level dataset
  119. prop.coloc::GLP1R
    GLP1R summary data included in the package
  120. RadialMR::data_radial
    Two Sample Summary GWAS data published in Do et al (2014).
  121. RMVMR::rawdat_rmvmr
    Raw multivariable MR summary data using lipid fractions as exposures and systolic blood pressure as an outcome.
  122. SlopeHunter::data_example
    Simulated effects on quantitative incidence and prognosis traits
  123. SUMnlmr::LDL_CAD
    UK Biobank dataset containing the allele score-associations with ldl-cholesterol and CAD diagnosis, by 10 quantiles of residual ldl.
  124. SUMnlmr::LDL_CAD_covar
    UK Biobank dataset containing the allele score-associations with ldl-cholesterol and CAD diagnosis adjusted for age, sex and first 10 principle components, by 10 quantiles of residual ldl.
  125. SUMnlmr::bmi_acm
    Hunt dataset containing the allele score-associations with bmi and all cause mortality, by 100 quantiles of residual BMI. As used in the paper "Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses" https://doi.org/10.1136/bmj.l1042
  126. SUMnlmr::generated_data
    Artificial genetic & phenotype data, for purposes of package tests