Package: MVMR 0.4.8

Tom Palmer

MVMR: MVMR

An R package for performing multivariable Mendelian randomization analyses.

Authors:Wes Spiller [aut], Jack Bowden [aut], Eleanor Sanderson [aut], Tom Palmer [aut, cre]

MVMR_0.4.8.tar.gz
MVMR_0.4.8.zip(r-4.7)MVMR_0.4.8.zip(r-4.6)MVMR_0.4.8.zip(r-4.5)
MVMR_0.4.8.tgz(r-4.6-any)MVMR_0.4.8.tgz(r-4.5-any)
MVMR_0.4.8.tar.gz(r-4.7-any)MVMR_0.4.8.tar.gz(r-4.6-any)
MVMR_0.4.8.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
MVMR/json (API)

# Install 'MVMR' in R:
install.packages('MVMR', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/wspiller/mvmr/issues

Pkgdown/docs site:https://wspiller.github.io

Datasets:
  • rawdat_mvmr - Raw multivariable MR summary data using lipid fractions as exposures and systolic blood pressure as an outcome.

On CRAN:

Conda:

8.38 score 54 stars 1 packages 356 scripts 10 exports 2 dependencies

Last updated from:bceaa38088. Checks:9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-x86_64OK140
source / vignettesOK248
linux-release-x86_64OK119
macos-release-arm64OK134
macos-oldrel-arm64OK115
windows-develOK84
windows-releaseOK88
windows-oldrelOK97
wasm-releaseOK123

Exports:format_mvmrivw_mvmrmrmvinput_to_mvmr_formatmvmrphenocov_mvmrpleiotropy_mvmrqhet_mvmrsnpcov_mvmrstrength_mvmrstrhet_mvmr

Dependencies:bootparallelly

Estimating phenotypic correlations
Covariance and Phenotypic correlations in MVMR | References
Rendered fromestimating-phenotypic-correlations.rmdusingknitr::rmarkdown

Last update: 2026-05-15
Started: 2026-05-15

Multivariable MR Tutorial
Overview | Workflow | Step 1: Obtain summary data | Estimating pairwise covariances between SNP associations | Step 2: Format summary data | Step 3: Test for weak instruments | Step 4: Test for horizontal pleiotropy using conventional Q-statistic estimation | Step 5: Estimate causal effects | Step 6: Robust causal effect estimation. | References
Rendered fromMVMR.rmdusingknitr::rmarkdown

Last update: 2026-05-15
Started: 2020-04-15