Package: simmrd 0.0.0.9000

Noah Lorincz-Comi

simmrd: Simulation of Mendelian Randomization data

This package generates simulation data to use in the evaluation of univariable or multivariable Mendelian Randomization methods. MR scenarios can include uncorrelated horizontal pleiotropy, correlated horizontal pleiotropy, weak instruments, winner's curse, and correlated SNP instruments.

Authors:Noah Lorincz-Comi [aut, cre]

simmrd_0.0.0.9000.tar.gz
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simmrd.pdf |simmrd.html✨
simmrd/json (API)

# Install 'simmrd' in R:

install.packages('simmrd', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/noahlorinczcomi/simmr/issues

On CRAN:

15 exports 3 stars 4.18 score 70 dependencies

Last updated 7 months agofrom:986323e3c9. Checks:OK: 7. Indexed: no.

Target	Result	Date
Doc / Vignettes	OK	Sep 16 2024
R-4.5-win	OK	Sep 16 2024
R-4.5-linux	OK	Sep 16 2024
R-4.4-win	OK	Sep 16 2024
R-4.4-mac	OK	Sep 16 2024
R-4.3-win	OK	Sep 16 2024
R-4.3-mac	OK	Sep 16 2024

Exports:adj_overlap ar1 biggwas classIVs generate_individual generate_summary makeBlocks parthcorr parthstd pfun plot_simdata plot_simdata_lower pruning setf std

Dependencies:abind backports BH boot broom car carData cli colorspace corrplot cowplot cpp11 Deriv doBy dplyr fansi farver generics ggplot2 ggpubr ggrepel ggsci ggsignif glue gridExtra gtable isoband labeling lattice lifecycle lme4 magrittr MASS Matrix MatrixModels mgcv microbenchmark minqa modelr munsell mvnfast nlme nloptr nnet numDeriv pbkrtest pillar pkgconfig polynom purrr quantreg R6 RColorBrewer Rcpp RcppArmadillo RcppEigen rlang rstatix scales SparseM stringi stringr survival tibble tidyr tidyselect utf8 vctrs viridisLite withr

Tutorial

Rendered fromtutorial.Rmdusingknitr::rmarkdownon Sep 16 2024.

Last update: 2024-01-05
Started: 2024-01-05

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
Helper function	adj_overlap
Helper function	ar1
Helper function	biggwas
Helper function	classIVs
An Individual-Level Data-Generating Function	generate_individual
An Summary Statistic Data-Generating Function	generate_summary
A function to make LD blocks	makeBlocks
Helper function	parthcorr
Helper function	parthstd
Helper function	pfun
Plot simulated data	plot_simdata
Helper function	plot_simdata_lower
Pruning SNPs	pruning
Helper function	setf
Helper function	std