Package: mrclust 0.1.0

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mrclust: Identifying Clustered Heterogeneity in Mendelian Randomization Analyses

Performs likelihood based clustering on univariate observations with known uncertainty (via standard error data), whilst accounting for possible null and junk components in the sample.

Authors:Christopher Neal Foley

mrclust_0.1.0.tar.gz
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mrclust_0.1.0.tgz(r-4.4-any)mrclust_0.1.0.tgz(r-4.3-any)
mrclust_0.1.0.tar.gz(r-4.5-noble)mrclust_0.1.0.tar.gz(r-4.4-noble)
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mrclust.pdf |mrclust.html✨
mrclust/json (API)

# Install 'mrclust' in R:

install.packages('mrclust', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/cnfoley/mrclust/issues

Datasets:

DBP_CAD - Genetic association data from diastolic blood pressure (DBP) and coronary artery disease (CAD) GWAS.
PP_CAD - Genetic association data from pulse pressure (PP) and coronary artery disease (CAD) GWAS.
SBP_CAD - Genetic association data from systolic blood pressure (SBP) and coronary artery disease (CAD) GWAS.

On CRAN:

2.82 score 12 stars 11 scripts 3 exports 89 dependencies

Last updated 3 years agofrom:039ed855bd. Checks:ERROR: 1 WARNING: 6. Indexed: no.

Target	Result	Date
Doc / Vignettes	FAIL	Oct 26 2024
R-4.5-win	WARNING	Oct 26 2024
R-4.5-linux	WARNING	Oct 26 2024
R-4.4-win	WARNING	Oct 26 2024
R-4.4-mac	WARNING	Oct 26 2024
R-4.3-win	WARNING	Oct 26 2024
R-4.3-mac	WARNING	Oct 26 2024

Exports:mr_clust_em pr_clust two_stage_plot

Dependencies:arrangements askpass base64enc bslib cachem cli codetools colorspace cpp11 crosstalk curl data.table DEoptimR digest dplyr evaluate fansi farver fastmap fontawesome foreach fs generics ggplot2 glmnet glue gmp gtable highr htmltools htmlwidgets httr isoband iterators iterpc jquerylib jsonlite knitr labeling later lattice lazyeval lifecycle magrittr MASS Matrix MatrixModels memoise MendelianRandomization mgcv mime munsell nlme numDeriv openssl pillar pkgconfig plotly promises purrr quantreg R6 rappdirs RColorBrewer Rcpp RcppArmadillo RcppEigen rjson rlang rmarkdown robustbase sass scales shape SparseM stringi stringr survival sys tibble tidyr tidyselect tinytex utf8 vctrs viridisLite withr xfun yaml

Vignettes and/or manual for this package failed to build, some documents may be unavailable. Please inspect thebuild logs for more information.

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
Genetic association data from diastolic blood pressure (DBP) and coronary artery disease (CAD) GWAS.	DBP_CAD
MR-Clust mixture model fitting	mr_clust_em
Genetic association data from pulse pressure (PP) and coronary artery disease (CAD) GWAS.	PP_CAD
Cluster size and assignemnt probabilities	pr_clust
Genetic association data from systolic blood pressure (SBP) and coronary artery disease (CAD) GWAS.	SBP_CAD
Plotting clustered ratio-estimates	two_stage_plot