Package: MRBEE 1.0.0

Noah Lorincz-Comi

MRBEE: Mendelian Randomization using Bias-Corrected Estimating Equation and Iterative Pleiotropy Testing

This package performs multivariate Mendelian randomization. It is characterized by the removal of measurement error bias caused by the estimation error of GWAS effect size estimates using an unbiased estimating function in measurement error analysis. It also utilizes a pleiotropy test to dynamically detect and remove potential pleiotropy, making the causal effect robust to pleiotropy.

Authors:Noah Lorincz-Comi [aut, cre], Yihe Yang [aut]

MRBEE_1.0.0.tar.gz
MRBEE_1.0.0.zip(r-4.7-any)MRBEE_1.0.0.zip(r-4.6-any)MRBEE_1.0.0.zip(r-4.5-any)
MRBEE_1.0.0.tgz(r-4.6-any)MRBEE_1.0.0.tgz(r-4.5-any)
MRBEE_1.0.0.tar.gz(r-4.7-any)MRBEE_1.0.0.tar.gz(r-4.6-any)
MRBEE_1.0.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
MRBEE/json (API)

# Install 'MRBEE' in R:
install.packages('MRBEE', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/noahlorinczcomi/mrbee/issues

Datasets:
  • hapmap3 - HapMap3 and UKBB Genotype SNP Data

On CRAN:

Conda:

3.16 score 9 stars 16 scripts 6 exports 7 dependencies

Last updated from:07c060cac5. Checks:7 NOTE, 2 OK. Indexed: no.

TargetResultTimeFilesSyslog
linux-develNOTE180
source / vignettesOK238
linux-releaseNOTE183
macos-releaseNOTE177
macos-oldrelNOTE154
windows-develNOTE113
windows-releaseNOTE118
windows-oldrelNOTE112
wasm-releaseOK119

Exports:errorCovfilter_alignJoint.testMRBEE.IMRPMRBEE.IMRP.EggerMRBEE.IMRP.UV

Dependencies:data.tableFDRestimationlatticeMASSMatrixrbibutilsRdpack