Package: MRBEE 1.0.0

Noah Lorincz-Comi

MRBEE: Mendelian Randomization using Bias-Corrected Estimating Equation and Iterative Pleiotropy Testing

This package performs multivariate Mendelian randomization. It is characterized by the removal of measurement error bias caused by the estimation error of GWAS effect size estimates using an unbiased estimating function in measurement error analysis. It also utilizes a pleiotropy test to dynamically detect and remove potential pleiotropy, making the causal effect robust to pleiotropy.

Authors:Noah Lorincz-Comi [aut, cre], Yihe Yang [aut]

MRBEE_1.0.0.tar.gz
MRBEE_1.0.0.zip(r-4.7)MRBEE_1.0.0.zip(r-4.6)MRBEE_1.0.0.zip(r-4.5)
MRBEE_1.0.0.tgz(r-4.6-any)MRBEE_1.0.0.tgz(r-4.5-any)
MRBEE_1.0.0.tar.gz(r-4.7-any)MRBEE_1.0.0.tar.gz(r-4.6-any)
MRBEE_1.0.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
MRBEE/json (API)

# Install 'MRBEE' in R:
install.packages('MRBEE', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/noahlorinczcomi/mrbee/issues

Datasets:
  • hapmap3 - HapMap3 and UKBB Genotype SNP Data

On CRAN:

Conda:

3.13 score 9 stars 15 scripts 6 exports 7 dependencies

Last updated from:07c060cac5. Checks:7 NOTE, 2 OK. Indexed: no.

TargetResultTimeFilesSyslog
linux-devel-x86_64NOTE167
source / vignettesOK198
linux-release-x86_64NOTE158
macos-release-arm64NOTE212
macos-oldrel-arm64NOTE163
windows-develNOTE122
windows-releaseNOTE113
windows-oldrelNOTE114
wasm-releaseOK132

Exports:errorCovfilter_alignJoint.testMRBEE.IMRPMRBEE.IMRP.EggerMRBEE.IMRP.UV

Dependencies:data.tableFDRestimationlatticeMASSMatrixrbibutilsRdpack