Package: MRBEE 0.1.0

Noah Lorincz-Comi

MRBEE: Mendelian Randomization using Bias-Corrected Estimating Equation and Iterative Pleiotropy Testing

This package performs multivariate Mendelian randomization. It is characterized by the removal of measurement error bias caused by the estimation error of GWAS effect size estimates using an unbiased estimating function in measurement error analysis. It also utilizes a pleiotropy test to dynamically detect and remove potential pleiotropy, making the causal effect robust to pleiotropy.

Authors:Noah Lorincz-Comi [aut, cre], Yihe Yang [aut]

MRBEE_0.1.0.tar.gz
MRBEE_0.1.0.zip(r-4.5)MRBEE_0.1.0.zip(r-4.4)MRBEE_0.1.0.zip(r-4.3)
MRBEE_0.1.0.tgz(r-4.5-any)MRBEE_0.1.0.tgz(r-4.4-any)MRBEE_0.1.0.tgz(r-4.3-any)
MRBEE_0.1.0.tar.gz(r-4.5-noble)MRBEE_0.1.0.tar.gz(r-4.4-noble)
MRBEE_0.1.0.tgz(r-4.4-emscripten)MRBEE_0.1.0.tgz(r-4.3-emscripten)
MRBEE.pdf |MRBEE.html✨
MRBEE/json (API)

# Install 'MRBEE' in R:
install.packages('MRBEE', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/noahlorinczcomi/mrbee/issues

Datasets:
  • hapmap3 - HapMap3 and UKBB Genotype SNP Data

On CRAN:

Conda:

3.00 score 5 stars 7 scripts 6 exports 7 dependencies

Last updated 6 months agofrom:6295549a1f. Checks:1 OK, 8 WARNING. Indexed: no.

TargetResultLatest binary
Doc / VignettesOKMar 25 2025
R-4.5-winWARNINGMar 25 2025
R-4.5-macWARNINGMar 25 2025
R-4.5-linuxWARNINGMar 25 2025
R-4.4-winWARNINGMar 25 2025
R-4.4-macWARNINGMar 25 2025
R-4.4-linuxWARNINGMar 25 2025
R-4.3-winWARNINGMar 25 2025
R-4.3-macWARNINGMar 25 2025

Exports:errorCovfilter_alignJoint.testMRBEE.IMRPMRBEE.IMRP.EggerMRBEE.IMRP.UV

Dependencies:data.tableFDRestimationlatticeMASSMatrixrbibutilsRdpack