Package: MRCorge 0.1.0

Wenmin Zhang

MRCorge: Mendelian Randomization based on the core gene hypothesis for polygenic exposures

This package performs Mendelian Randomization (MR) analyses based on the core gene hypothesis for polygenic exposures. MR CORGE identifies a small number of putative core instruments that are more likely to affect genes with a direct biological role in an exposure and obtains causal effect estimates based on these instruments, thereby reducing the risk of horizontal pleiotropy.

Authors:Wenmin Zhang [aut, cre], Tianyuan Lu [aut]

MRCorge_0.1.0.tar.gz
MRCorge_0.1.0.zip(r-4.7)MRCorge_0.1.0.zip(r-4.6)MRCorge_0.1.0.zip(r-4.5)
MRCorge_0.1.0.tgz(r-4.6-any)MRCorge_0.1.0.tgz(r-4.5-any)
MRCorge_0.1.0.tar.gz(r-4.7-any)MRCorge_0.1.0.tar.gz(r-4.6-any)
MRCorge_0.1.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
card.svg |card.png
MRCorge/json (API)

# Install 'MRCorge' in R:
install.packages('MRCorge', repos = c('https://mrcieu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/zhwm/mrcorge/issues

Pkgdown/docs site:https://zhwm.github.io

On CRAN:

Conda:

3.30 score 4 stars 6 scripts 3 exports 88 dependencies

Last updated from:f2464f6e07. Checks:7 WARNING, 2 OK. Indexed: no.

TargetResultTimeFilesSyslog
linux-devel-x86_64WARNING141
source / vignettesOK209
linux-release-x86_64WARNING134
macos-release-arm64WARNING77
macos-oldrel-arm64WARNING99
windows-develWARNING78
windows-releaseWARNING77
windows-oldrelWARNING86
wasm-releaseOK123

Exports:mrcorgeplot_mrcorgeQstatistic

Dependencies:askpassbase64encbslibcachemclicodetoolscowplotcpp11crosstalkcurldata.tabledigestdplyrevaluatefarverfastmapfontawesomeforeachfsgenericsggplot2glmnetglueGPArotationgridExtragtablehighrhtmltoolshtmlwidgetshttrieugwasrisobanditeratorsjquerylibjsonliteknitrlabelinglaterlatticelazyevallifecyclemagrittrMASSMatrixmemoisemimemnormtMRMixMRPRESSOnlmeopensslotelpbapplypillarpkgconfigplotlyplyrpromisespsychpurrrR6RadialMRrappdirsRColorBrewerRcppRcppEigenreshape2rlangrmarkdownS7sassscalesshapestringistringrsurvivalsystibbletidyrtidyselecttinytexTwoSampleMRutf8vctrsviridisLitewithrxfunyaml

Negative control example: HDL->CAD

Rendered fromHDL_CAD.Rmdusingknitr::rmarkdownon May 15 2026.

Last update: 2024-07-17
Started: 2024-07-17